• Journal of the Korea Society of Computer and Information
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• v.15 no.10
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• pp.229-237
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• 2010

Recently, forest management objectives become more complex and complicated, and spatial constraints were necessarily considered for ecological stability. Now forest planning is required to provide an optimized solution that is able to achieve a number of management objectives and constraints. In this study, we developed a decision supporting system based on the one of dynamic planning techniques, Tabu Search (TS) heuristic algorithm, which enable one to generate an optimized solution for given objectives and constraints. For this purpose, we analyzed the logical flow of the algorithm and designed the subsequence of processes. To develop a high-performance computing system, we examined a number of strategy to minimize execution time and workloads in each process and to maximize efficiency of using system resources. We examined two model based on the original TS algorithm and revised version of TS algorithm and compared their performance in optimization process. The results showed high performance of the developed system in providing feasible solutions for several management objectives and constraints. Moreover, the revised version of TS algorithm was appeared to be more stable for providing results with minimum variation. The developed system is expected to use for developing forest management plans in Korea.

• Journal of Navigation and Port Research
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• v.39 no.1
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• pp.23-28
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• 2015

This paper is to identify the dynamic phenomenon of the marine pollution management that is connected directly or indirectly by using system dynamics analysis. The method used herein is based on system dynamics analysis that analyzed the sub-systems for marine pollution management. Furthermore designed feedback loop between system elements. And made total casual map of marine pollution management. The main results of the paper are the following : 1. It's necessary to equipments and technology development and law revision for feedback loop slump of initial measures delay in oil spill. 2. It should be come up with partnerships and new business for community corrosion non-proliferation caused by social conflicts. 3. Marine pollution management should be an obligation that must be minimized to include social conflicts in the community and national levels besides oil spill response on-site. This model confirmed the hidden cause of delay by existing response plans, manuals and programs. And oil spill response in broader sense is more important from now on. The result can be useful in the guidance of marine pollution and management.

• Korean Journal of Environmental Biology
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• v.34 no.1
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• pp.56-62
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• 2016

Pest population density models are very important to monitor the initial occurrence and to understand the continuous fluctuation pattern of pest in pest management. This is one of the major issues in agriculture because these predictions make pesticides more effective and environmental impact of pesticides less. In this study, we combined and predicted the mortality change of pest caused by pesticides with temperature change and population dynamic model. Sensitive strain of two-spotted spider mite (Tetranychus urticae Koch) with kidney bean leaf as host was exposed to mixed acaricide, Acrinathrin-Spiromesifen and organotin acaricide, Azocyclotin, at 20, 25, 30, and $35^{\circ}C$, respectively. There was significant difference in mortality of T. urticae among pesticides and temperatures. We used DYMEX to simulate population density of T. urticae and predicted that the initial management time and number of chemical control would be changed in the future with climate change. There would be implications for strategies for pest management and selection process of pesticide in the future corresponding climate change.

• Korean Journal of Environment and Ecology
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• v.29 no.3
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• pp.410-420
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• 2015

In order to estimate the influence of environmental factors on zooplankton communities in lentic freshwater ecosystems, 20 reservoirs and wetlands were monitored by season in 2013. A total of 109 species of zooplankton were identified during the study period. Zooplankton assemblage showed a different distribution in its density and diversity in accordance with the seasons. In particular, the density of zooplankton (98 species and 603ind. L-1) was the most in autumn when compared to the other seasons. In order to effectively analyze zooplankton distribution that are affected by various environmental factors, a Self-Organizing Map (SOM) was used, which extracts information through competitive and adaptive properties. A total of 11 variables (8 environment factors and 3 groups of zooplankton) were patterned on to the SOM. Based on a U-matrix, four clusters were identified from the model. Among zooplankton communities, rotifer displayed a positive relationship with water temperature, and cladocerans and copepod were positively related to conductivity, chlorophyll a, and nutrient factor (i. e. TN and TP). In contrast, high dissolved oxygen appeared to have a negative effect on zooplankton distribution. Consequently, the SOM results depicted a clear pattern of zooplankton density clusters partitioned by environmental factors, which play a key role in determining the seasonal distribution of zooplankton groups in lentic freshwater ecosystem.

• Journal of Ginseng Research
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• v.46 no.1
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• pp.156-166
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• 2022

Background: Panax ginseng Meyer (P. ginseng), a herb distributed in Korea, China and Japan, exerts benefits on diverse inflammatory conditions. However, the underlying mechanism and active ingredients remains largely unclear. Herein, we aimed to explore the active ingredients of P. ginseng against inflammation and elucidate underlying mechanisms. Methods: Inflammation model was constructed by lipopolysaccharide (LPS) in C57BL/6 mice and RAW264.7 macrophages. Molecular docking, molecular dynamics, surface plasmon resonance imaging (SPRi) and immunofluorescence were utilized to predict active component. Results: P. ginseng significantly inhibited LPS-induced lung injury and the expression of proinflammatory factors, including TNF-α, IL-6 and IL-1β. Additionally, P. ginseng blocked fluorescencelabeled LPS (LPS488) binding to the membranes of RAW264.7 macrophages, the phosphorylation of nuclear factor-κB (NF-κB) and mitogen-activated protein kinases (MAPKs). Furthermore, molecular docking demonstrated that ginsenoside Ro (GRo) docked into the LPS binding site of toll like receptor 4 (TLR4)/myeloid differentiation factor 2 (MD2) complex. Molecular dynamic simulations showed that the MD2-GRo binding conformation was stable. SPRi demonstrated an excellent interaction between TLR4/ MD2 complex and GRo (K_D value of 1.16 × 10^-9 M). GRo significantly inhibited LPS488 binding to cell membranes. Further studies showed that GRo markedly suppressed LPS-triggered lung injury, the transcription and secretion levels of TNF-α, IL-6 and IL-1β. Moreover, the phosphorylation of NF-κB and MAPKs as well as the p65 subunit nuclear translocation were inhibited by GRo dose-dependently. Conclusion: Our results suggest that GRo exerts anti-inflammation actions by direct inhibition of TLR4 signaling pathway.

• Journal of Aerospace System Engineering
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• v.18 no.1
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• pp.37-45
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• 2024

This paper presents a design approach for passive vibration control to reduce vertical vibrations transmitted to the control unit during hovering flight of a quadrotor drone. Ground vibration test simulation based on finite element model was performed for forced vibration analysis of the quadrotor drone. First, modal analysis was performed to evaluate dynamic characteristics. Forced vibration response analysis was then performed to obtain the steady-state response within the operating frequency range under the hovering flight condition. Furthermore, to obtain the vibration reduction effect, a viscous damping tape was applied at positions that could induce vibrations transmitted to the control unit under the same conditions. Such a passive vibration control approach was investigated. Relevant vibration reduction effect was assessed with respect to the application of damping materials and the attachment position.

• Smart Media Journal
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• v.13 no.3
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• pp.18-26
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• 2024

Road surface monitoring is essential for maintaining road environment safety through managing risk factors like rutting and crack detection. Using autonomous driving-based UGVs with high-performance 2D laser sensors enables more precise measurements. However, the increased energy consumption of these sensors is limited by constrained battery capacity. In this paper, we propose a fusion sensor system for efficient surface monitoring with UGVs. The proposed system combines color information from cameras and depth information from line laser sensors to accurately detect surface displacement. Furthermore, a dynamic sampling algorithm is applied to control the scanning frequency of line laser sensors based on the detection status of monitoring targets using camera sensors, reducing unnecessary energy consumption. A power consumption model of the fusion sensor system analyzes its energy efficiency considering various crack distributions and sensor characteristics in different mission environments. Performance analysis demonstrates that setting the power consumption of the line laser sensor to twice that of the saving state when in the active state increases power consumption efficiency by 13.3% compared to fixed sampling under the condition of λ=10, µ=10.

• Asia-Pacific Journal of Business Venturing and Entrepreneurship
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• v.14 no.6
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• pp.11-27
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• 2019

The second venture "boom" diffusion strategy can be confirmed to be focused only on financing investment and finance, including achieving 5 trillion won annually in new venture investments, creating 20 unicorns, activating M&As and creating dynamic recovery markets. Of course, existing studies show that the fund is a very important policy for corporate growth, but various policy support will be needed to effectively scale up. To overcome these limitations, the scale-up support policies already in operation are analyzed by introducing scale-up policies in advanced countries such as the U.S. and Britain. It also aims to analyze domestic scale-up policies to draw up implications for establishing more effective scale-up policies. Academically, we are very lacking in research on scale-up at home and abroad, and we propose suggestions through this comparative study of policy cases to contribute to the promotion of various studies related to the scalability aspects of future research topics related to scale-up.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.36 no.2
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• pp.105-113
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• 2010

This study introduces a flexible approach to enhance skin permeation by using ethosomes with deformable lipid membranes as well as controllable sizes. To demonstrate this, a set of ethosomes encapsulating an anti-hair loss ingredient, Triaminodil$^{TM}$, as a model drug, were fabricated with varying their size, which was achieved by solely applying the different level of mechanical energy, while maintaining their chemical composition. After characterization of the ethosomes with dynamic light scattering, transmission electron microscopy, and deformability measurements, it was found that their membrane deformability depended on the particle size. Moreover, studies on in vitro skin permeation and murine anagen induction allowed us to figure out that the membrane deformability of ethosomes essentially affects delivery efficiency of Triaminodil$^{TM}$ through the skin. It was noticeable in our study that there existed an optimum particle size that can not only maximize the delivery of the drug through the skin, but also increase its actual dermatological activity. These findings offer a useful basis for understanding how ethosomes should be designed to improve delivery efficiency of encapsulated drugs therein in the aspects of changing their length scales and membrane properties.

• Korean Journal of Applied Biomechanics
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• v.31 no.1
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• pp.1-15
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• 2021

Objective: The aim of this study was to investigate 1) the difference in static lower extremity alignment (SLEA) according to a history of lateral ankle sprain (LAS), 2) to identify SLEA factors affecting LAS, and 3) to present the cut-off value and 4) the usefulness and limitations of the SLEA measurement. Method: This case-control study recruited 88 men (age: 27.78±4.69 yrs) and 39 women (age: 24.62±4.20 yrs) subjects with and without LAS. SLEA measurement protocol included Q angle, tibiofemoral angle, genu recurvatum, rear foot (RF) angle, tibal varum and torsion, navicular drop, ankle dorsiflexion range of motion (DF ROM). Independent t-test, logistic regression and receiver operating characteristic (ROC) curve were used for statistical analysis. Results: Men with a history of LAS had significantly smaller Q angles both in standing and in supine position, while women with a history of LAS had significantly greater DF ROM in non-weight bearing (NWB; p < 0.05). Logistic regression model suggests tibial varum (OR = 0.779, p = 0.021) and WB DF ROM (OR = 1.067, p = 0.045) were associated with LAS in men. In case of women, there were no significant SLEA factors for LAS, however, ROC curve analysis revealed standing RF angle (AUC = 0.647, p = 0.028) and NWB DF ROM (AUC = 0.648, p = 0.026) could be affecting factors for LAS. Conclusion: There are differences in SLEA according to the history of LAS, furthermore, the identified items were different by sex. In case of men, tibial varum and WB DF ROM affect LAS occurrence. Standing RF angle and NWB DF ROM of women could be a predictor for LAS. However, since the sensitivity and specificity in most of the SLEA measurements are low, kinematic in dynamic tasks should be considered together for a more accurate evaluation of LAS risk.