• Journal of Photoscience
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• 제9권2호
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• pp.451-453
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• 2002

A new concept of "photo" -antisense method has been evaluated, where the inhibition of gene expression by the conventional antisense method is enhanced by photochemical binding between antisense oligonucleotides conjugated with photo-reactive compound and target mRNA or DNA. Fluorescein labeled oligodeoxyribonucleotides (F-DNA) was delivered to cell nuclei in the encapsulated form in multilamellar lecithin liposomes with neutral charge. F-DNA was previously shown to photo-bind to the complementary stranded DNA, and the delivery system using neutral liposome to be effective in normal human keratinocytes. In the present study, we used human kidney cancer G401.2/6TG.1 cell line to be advantageous in reproducible experiments. p53 was adopted as a target gene since antisense sequence information has been accumulated. The nuclear localization ofF-DNA was identified by comparing the fluorescence ofF-DNA with that of Hoechst 33258 under fluorescence microscope. After 7hr incubation to accumulate p53 protein induced by UV -B, p53 protein was quantified by Western blot. After 2hrs from F-DNA application, about 30% of cell population incorporated F-DNA in their nuclei with some morphological change possibly due to liposomal toxicity. Irradiation of visible light longer than 400nm from solar simulator at this time enhanced the inhibitory action of antisense F-DNA. The present results suggest that photo-antisense method is promising to control gene expression in time and space dependent manner. Further improvement of F-DNA delivery to cancer cells in the stability and toxicity is in progress. progress.

• Bulletin of the Korean Chemical Society
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• 제33권10호
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• pp.3407-3412
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• 2012

The Ti incorporation at Fe-site in the double perovskite lattice of $Sr_2FeNbO_6$ (SFNO) system is studied. The Ti concentration optimization yielded an efficient photocatalyst. At an optimum composition of Ti as x = 0.07 in $Sr_2Fe_{1-x}Ti_xNbO_6$, the photocatalyst exhibited 2 times the quantum yield for photolysis of $H_2O$ in presence of $CH_3OH$, than its undoped counterpart under visible light (${\lambda}{\geq}420nm$). Heavily Ti-doped $Sr_2Fe_{1-x}Ti_xNbO_6$ lattice exhibited poor photochemical properties due to the existence of constituent impurity phases as observed in the structural characterization, as well as deteriorated optical absorption. The higher electron-density acquired by n-type doping seem to be responsible for the more efficient charge separation in $Sr_2Fe_{1-x}Ti_xNbO_6$ (0.05 < x < 0.4) and thus consequently displays higher photocatalytic activity. The Ti incorporated structure also found to yield stable photocatalyst.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• 제44권8호
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• pp.741-757
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• 2016

Over 60 years has passed since mankinds started space exploration beyond the Earth with lunar explorer Luna 1 launched by Soviet Union. Unprecedently remarkable outcomes have been obtained by sending unmanned spacecrafts to most planets in the solar system and having the lander landed on the approaching comet toward the Earth even though any evidence of life presence has not been discovered yet. Only moon is an natural object beyond the earth on which human beings landed. Many countries are planning to send humans to the moon or mars to build colonies and to survive with substantiality. Korean lunar exploration program has officially started as of 2016 after its plan including lunar exploration has been specified in the series of National Space Promotion Plan since Korea initiated space development in early 1990s. In this paper, the plan for Korean space exploration is summarized with reviewing overseas space exploration program status and trends.

• Journal of Korean Society for Atmospheric Environment
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• 제24권4호
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• pp.423-438
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• 2008

BEIS2 (Biogenic Emissions Inventory System version 2) and BEIS3.12 (BEIS version 3.12) were used to estimate hourly biogenic emissions over South Korea using a set of vegetation and meteorological data simulated with the MM5 (Mesoscale Model version 5). Two biogenic emission models utilized different emission factors and showed different responses to solar radiations, resulting in about $10{\sim}20%$ difference in the nationwide isoprene emission estimates. Among the 11-vegetation classes, it was found that mixed forest and deciduous forest are the most important vegetation classes producing isoprene emissions over South Korea comprising ${\sim}90%$ of the total. The simulated isoprene concentrations over Seoul metropolitan area show that diurnal and daily variations match relatively well with the PAMS (Photochemical Air Monitoring Station) measurements during the period of June 3${\sim}$June 10, 2004. Compared to BEIS2, BEIS3.12 yielded ${\sim}35%$ higher isoprene concentrations during daytime and presented better matches to the high peaks observed over the Seoul area. This study showed that the importance of vegetation data and emission factors to estimate biogenic emissions. Thus, it is expected to improve domestic vegetation categories and emission factors in order to better represent biogenic emissions over South Korea.

• Journal of the Mineralogical Society of Korea
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• 제24권1호
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• pp.31-36
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• 2011

Meteorites are extraterrestrial solid rock fragments that fell from the outer space. Investigating mineral magnetic properties of the Meteorites is essential in understanding the evolution of planets and asteroids in the Solar System. In particular, magnetic characterization of magnetic mineral can provide constraints on the progress of differentiation in ancient planetary bodies. In the present study, ratio of thermoremanent magnetization (TRM) over saturation isothermal remanent magnetization (SIRM) was applied to diagnose the magnetic minerals in meteorites and igneous rocks. Distinctive classification of TRM/SIRM suggests that kamacite, tetrataenite, magnetite, and (Cr,Ti)-rich iron oxide are responsible for the magnetization of H5 Richardton, LL6 St. Severin, ALH84001, and DaG476, respectively. The TRM/SIRM ratio could be an efficient tool in identifying magnetic minerals especially when rocks or meteorites contain unstable material under heating.

• Journal of Astronomy and Space Sciences
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• 제14권2호
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• pp.375-380
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• 1997

The accuracy of user position by GPS is heavily dependent upon the accuracy of satellite position which is usually transmitted to GPS users in radio signals. The real-time satellite position information directly obtained from broadcast ephimerides has the accuracy of 3~10 meters which is very unsatisfactory to measure 100km baseline to the accuracy of less than a few mili-meters. There are globally at present seven orbit analysis centers capable of generating precise GPS ephimerides and their orbit quality is of the order of about 10cm. Therefore, precise orbit model and phase processing technique were reviewed and consequently precise GPS ephimerides were produced after processing the phase observables of 28 global GPS stations for 1 day. Initial 6 orbit parameters and 2 solar radiation coefficients were estimated using batch least square algorithm and the final results were compared with the orbit of IGS, the International GPS Service for Goedynamics.

• Journal of Magnetics
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• 제21권4호
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• pp.509-515
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• 2016

We report on development of a ground-based bi-axial Search-Coil Magnetometer (SCM) designed to measure time-varying magnetic fields associated with magnetosphere-ionosphere coupling processes. The instrument provides two-axis magnetic field wave vector data in the Ultra Low Frequency or ULF (1 mHz to 5 Hz) range. ULF waves are well known to play an important role in energy transport and loss in geospace. The SCM will primarily be used to observe generation and propagation of the subclass of ULF waves. The analog signals produced by the search-coil magnetic sensors are amplified and filtered over a specified frequency range via electronics. Data acquisition system digitizes data at 10 samples/s rate with 16-bit resolution. Test results show that the resolution of the magnetometer reaches $0.1pT/{\sqrt{Hz}}$ at 1 Hz, and demonstrate its satisfactory performance, detecting geomagnetic pulsations. This instrument is scheduled to be installed at the Korean Antarctic station, Jang Bogo, in the austral summer 2016-2017.

• Journal of the Korean Society of Industry Convergence
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• 제26권5호
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• pp.953-965
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• 2023

The stratospheric drones are developed to perform missions such as weather observation, communication relay, surveillance, and reconnaissance at 18km to 20km, where climate change is minimal and there is no worry about a collision with aircraft. It uses solar panels for daytime flights and energy stored in batteries for night flights, providing many advantages over existing satellites. The electrical and power systems essential for stratospheric drone flight must ensure reliability, efficiency, and lightness by selecting the optimal circuit topology. Therefore, it is necessary to analyze the circuit topology of various types of multi-level inverters with high redundancy that can ensure the reliability and efficiency of the motor driving power required for stable long-term flight of stratospheric drones. By quantifying the switch element voltage drop and the number and weight of inverter components for each topology, we evaluate efficiency and lightness and propose the most suitable circuit topology for stratospheric drones.

• Korean Chemical Engineering Research
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• 제58권3호
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• pp.416-423
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• 2020

Majority of over 100 kW capacity photo voltaic (PV) power generation system was constructed on the plate ground of soil. Rarely PV system installed on concrete or building but it usually be under 25 kW capacity. On the soil ground the weeds growen up and it's shadow influenced to decrease of amount of PV power generation. This work analysis the weeds shadow's effect to decrease of PV power generation with 100 kW capacity of real PV power generation system in Yeungnam University, Finally the weed shadow"s influence value through the real field monitoring Data is suggested for give a standard management time of weeds to avoid the negative influence on whole power plant. Moreover the hot spot which is generated by long term partial shallow on PV module also can detected with the result of this work. It also suggested as a standard value of monitoring Data.

• Korean Journal of Remote Sensing
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• 제39권3호
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• pp.257-268
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• 2023

Sea ice plays an important role in Earth's climate by regulating the amount of solar energy absorbed and controlling the exchange of heat and material across the air-sea interface. Its growth, drift, and melting are monitored on a regular basis by satellite observations. However, low-resolution products with passive microwave radiometer have reduced accuracy during summer to autumn when the ice surface changes rapidly. Synthetic aperture radar (SAR) observations are emerging as a powerful complementary, but previous researches have mainly focused on winter ice. In this study, sea ice drift tracking was evaluated and analyzed using SAR images and tracker with global positioning system (GPS) during late summer-early autumn period when ice surface condition changes a lot. The results showed that observational uncertainty increases compared to winter period, however, the correlation coefficient with GPS measurements was excellent at 0.98, and the performance of the ice tracking algorithm was proportional to the sea ice concentration with a correlation coefficient of 0.59 for ice concentrations above 50%.