• Journal of Clinical Nutrition
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• 제10권2호
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• pp.38-44
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• 2018

Purpose: Parenteral nutrition (PN) is known to provide therapeutic beneficial improvements in malnourished patients for whom enteral nutrition is not feasible. The objective of this study was to investigate the current clinical characteristics and utilization of PN in Korea. Methods: We analyzed the Health Insurance Review Agency National Inpatients Sample database from 2014 to 2016, which included 13% of all hospitalized patients in Korea. Adult patients aged 20 years or older and receiving premixed multi-chamber bag containing PN were included for this study. Patient characteristics, admission type, primary diagnosis, and hospital demographics were evaluated. SAS version 9.4 was used for data analysis. Results: From 2014 to 2016, 149,504 patients received premixed PN, with 226,281 PN prescriptions being written. The mean patient age was 65.0 years, and 81,876 patients (54.8%) were male. Premixed 3-chamber bag and 2-chamber bag PN solutions were utilized in 131,808 (88.2%) and 32,033 (21.4%) patients, respectively. The number of patients hospitalized through the emergency department were 70,693 (47.3%), whereas 43,125 patients (28.8%) were administered PN in intensive care units. In the adult PN patients, the highest primary diagnosis was malignant neoplasm of the stomach (8,911, 6.0%), followed by organism unspecified pneumonia (7,008, 4.7%), and gastroenteritis and colitis of unspecified origin (6,381, 4.3%). Overall, 34% of adult PN patients were diagnosed with malignancies, the most common being neoplasm of the stomach (17.7%), neoplasm of bronchus/lung (11.2%), neoplasm of colon (11.1%), and neoplasm of liver/intrahepatic bile ducts (10.0%). PN solutions were most frequently administered in the metropolitan area (55.0%) and in hospitals with more than 1,000 beds (23.6%). Conclusion: PN was commonly administered in older patients, with primary diagnosis of malignancy in a significant number of cases. This study is the first large-scale description of PN-prescribing patterns in real-world clinical practice in South Korea.

• 대한두경부종양학회지
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• 제21권1호
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• pp.21-25
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• 2005

Background and Objectives: The popularity of complementary and alternative medicine(CAM) has grown at an astonishing rate in recent years. Because patients are interested in CAM and want to use it, physicians also should be concerned about CAM and know about the current situation of its usage. In this study, we tried to determine the prevalence of CAM use in the patients with head and neck cancer and correlate with demographics and tumor characteristics. Materials and Methods: A total of 87 patients with head and neck cancer previously treated with surgery at Seoul National University Hospital from March through June, 2004 were enrolled in this study. The patients were completed, questionnaire about the use of CAM and demographic information. Tumor characteristics were obtained from the patient's medical records. Results: Of the 87 patients, 33 patients(37.9%) use at least one CAM. There was no statistically significant correlation between patient's data and prevalence of CAM use. Of those patients using CAM, 16(48.5%) of 33 were using 2 or more therapies. The majority of agents used by patients in this study are mushrooms such as Phellinus and Reishi, followed by dietary therapy. A majority(60.6%) of patients were introduced to alternative medicine by friends or family members. Conclusion: Considerable cancer patients use CAM. Head and neck oncologists should inform themselves about CAM to counsel and educate the patients. Further scientific investigations on promising CAM agents may help advance cancer treatment.

• 대한한의학회지
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• 제30권5호
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• pp.163-173
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• 2009

Objective: This study sought a clinical analysis of hepatobiliary cancer patients treated by oriental medical therapy. Methods: 312 hepatobiliary cancer patients treated in East-west Cancer Center of Dunsan Oriental Hospital from October 2004 to September 2008 were reviewed. These patients' general characteristics and clinical change after treatment were investigated. Results: 83.3% of patients' tumors were stage IV. The median survival period of stage IV patients was 107.0$\pm$82.2 (IVa), 207.0$\pm$26.8 (IVb) days (hepatocellular carcinoma), 132.0$\pm$15.8 days (cholangiocarcinoma), and 203.0$\pm$24.6 days (gallbladder carcinoma). Conclusions: This study presents the general characteristics of hepatobiliary cancer patients treated by Oriental medical therapies, and thus would be valuable for further studies of Oriental medicine-based cancer treatments.

• Clinical and Experimental Pediatrics
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• 제58권10호
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• pp.380-385
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• 2015

Purpose: Croup is a common pediatric respiratory illness with symptoms of varying severity. Moreover, epiglottitis is a rare disease that can rapidly progress to life-threatening airway obstruction. Although the clinical course and treatments differ between croup and epiglottitis, they are difficult to differentiate on presentation. We aimed to compare the clinical characteristics of croup and epiglottitis in Emergency Department patients. Methods: The 2012 National Emergency Department Information System database of 146 Korean Emergency Departments was used to investigate patients aged ${\leq}18years$ presenting with croup or epiglottitis. Results: We analyzed 19,374 croup patients and 236 epiglottitis patients. The male:female sex ratios were 1.9:1 and 2.3:1 and mean ages were $2.2{\pm}2.0$ and $5.6{\pm}5.8years$, respectively. The peak incidence of croup was observed in July and that of epiglottitis was observed in May. The hospitalization rate was lower in croup than in epiglottitis patients, and the proportion of patients treated in the intensive care unit was lower among croup patients. The 3 most common chief complaints in both croup and epiglottitis patients were cough, fever, and dyspnea. Epiglottitis patients experienced dyspnea, sore throat, and vomiting more often than croup patients (P<0.05). Conclusion: Both groups had similar sex ratios, arrival times, 3 most common chief complaints, and 5 most common comorbidities. Epiglottitis patients had a lower incidence rate, higher mean age of onset, and higher hospitalization rate and experienced dyspnea, sore throat, and vomiting more often than croup patients. Our results may help in the differential diagnosis of croup and epiglottitis.

• 대한임상독성학회지
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• 제8권2호
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• pp.61-68
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• 2010

Purpose: Poisoning is a major health problem for the elderly, and poisoning can cause fatal side effects. However, the characteristics and clinical features of elderly patients with acute poisoning have not been well studied in the previous domestic research. So, we tried to analyze the clinical characteristics and toxic substances of the patients who were 65 years old or older and who were admitted to the regional emergency medical center due to acute poisoning. Methods: We retrospectively reviewed the medical records and poisoning protocols of the patients who were 65 years of age or older and who had with acute poisoning and who visited the ED in our emergency center from January 2005 to December 2009. We collected the demographic information, the gender, the underlying diseases, the causes and toxic substances, the initial presentation, the treatment and the outcomes. Results: A total of 2179 poisoned patients visited the hospital during 5 years, and among them 244 were 65 years of age or older (11.2%). The mean age was $75.6{\pm}6.9$ years and the male:female ratio was 1:1.7. The most common cause of poisoning was suicide (73.4%) and the most common source of poisonous substances was their own drugs. Of the substances used for poisoning, benzodiazepine was the most common drug (25.8%), followed by sedatives other than benzodiazepine (25.4%), insecticide (12.7%), chemical agents (12.3%) and herbicides (8.2%). The most common initial presentation was mental change (64.8%). When comparing the factors between the three elderly groups, there was no difference in gender, the cause, the substances and the underlying disease. The outcomes of treatment included ICU admission (56.1%), a good condition at discharge (12.7%) and admission to a general ward (12.7%). The overall mortality rate was 10.2% for the elderly patients. Conclusion: In this Korean study, unlike the foreign studies, the most common cause of poisoning in elderly patients was intentional poisoning. The admission rate was 68.8% and mortality rate was 10.2%.

• 동의신경정신과학회지
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• 제20권3호
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• pp.189-203
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• 2009

Objectives : This study was to analyze characteristics of MMPI profile, personality and defensive mechanism on 32 Hwa-byeng patients. Methods : 32 Hwa-byeng patients and 28 normal control group were administered the MMPI. The characteristics of MMPI profile and the clinical scales of personality and defensive mechanism were analyzed statistically. Results : 1. Half of female Hwa-byeng patients are in their forties, twelve patients are high school graduates, housewives seem to have Hwa-byeng more than workers, and married ones have Hwa-byeng more than singles, divorcees or separated one 2. 60.6% patients are getting stressed from their husbands(the specific reasons are infidelity(55%), incapability(25%) and violence(20%)). And the rest are from in-law(28.8%), children(6.4%) and their own parents(3.2%). 3. MMPI profile of Hwa-byeng patients appeared as a type of 3-1 elevated by the scale of 3(Hy) and 1 (Hs). And Hwa-byeng patients appeared significantly high in the rest of scales except L, K, Mf and Ma scales comparing to control group. 4. Hwa-byeng patients were classified into 3 groups. First group is "V" type which is high in K scale and low in 3 (Hy), 4(Pd), 6(Pa). Second group is "V" type which is high in K scale and high in 3(Hy), 4(Pd), 6(Pa). Third group is high in F scale and high in 1(Hs), Z(D), 3(Hy), 4(Pd), 6(Pa), 7(Pt), 8(Sc) and 0(Si). 5. The analysis on MMPI profiles indicates that the thirties are highier in F scale than the fifties, the fifties are highier in Hy scale than the forties, workers are highier in Pd scale than housewives, singles or divorcees are highier in Pa scale than the married. 6. The characteristics of personality in Hwa-byeng patients are as follows. They are significantly lower in HST, NAR and very higher in CPS, PAG, DEP, STY, AVD, SZD comparing to control group. Especially in AVD and SZD scales are appeared the highest.

• 동서간호학연구지
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• 제10권1호
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• pp.106-116
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• 2004

This study is about the quality of life of cerebral infarction patients' guardians. The subject of this study was a group of 159 guardians of patients diagnosed of cerebral infarction and being hospitalised in a general hospital located in Seoul. The measurement tool consisted of quality of life of cerebral infarction patients' guardian, self-esteem, burden of responsibility, family unity, health status of the guardian. The collected data have been processed using SPSS/PC 12.0 programme: The results of this study are as follows: 1. The point for quality of life of cerebral infarction patients' guardians was 3.08(five-point scale), and for the related factors, the points for self-esteem was 3.67, burden of responsibility was 3.26, family unity was 4.13, health status was 6.10(ten-point scale). 2. There was a significant difference in the quality of life according to Self-esteem, Burden of responsibility, Family unity and general characteristics. 3. In the quality of life of cerebral infarction patients' guardians, a positive correlation was noted in some factors according to the characteristics of the guardians such as health status, self-esteem, family unity, monthly income, and time spent for caring the patient. Whilst a negative correlation was noted in the others such as burden of responsibility and age of the guardian. By confirming the results above, it is concluded that we must understand the major factors which are related to quality of life, find the causes that deteriorate the quality of life, and apply proper nursing intervention to improve the quality of life of cerebral infarction patients' guardians.

• Pediatric Infection and Vaccine
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• 제20권2호
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• pp.89-97
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• 2013

목 적 : 국내 B형 인플루엔자의 임상 양상 및 A형 인플루엔자와 비교를 위해 후향적 연구를 시행하였다. 방 법 : 2011-2012 인플루엔자절기에 multiplex PCR로 인플루엔자가 진단된 소아청소년 입원 환자들의 의무 기록 분석으로 B형 인플루엔자의 임상 양상과 함께 같은 기간 A형 인플루엔자와의 차이점을 조사하였다. 결 과 : 연구 기간 동안 진단 된 145명 인플루엔자 환자 중, A형 인플루엔자 66명, B형 인플루엔자 78명이 있었고, 1명은 A, B형 인플루엔자가 동시에 진단되었다. 이들은 기침(88.2%), 콧물(77.1%), 가래(60.4%) 등 호흡기 증상을 호소하며, 하기도 감염(49.3%) 및 상기도 감염(31.9%)으로 진단된 경우가 많았다. B형과 A형 인플루엔자 환자의 주요 증상 및 검사실 소견은 차이가 없었고, A형에 비해 B형 인플루엔자 환자의 입원 전 발열기간이 길었다(3.0일 vs. 2.5일, P=0.043). 결 론 : 임상 양상만으로 B형과 A형 인플루엔자 감별은 제한성이 있고, B형 인플루엔자 환자의 입원 전 발열 기간 3일을 고려한다면 진단 후 치료보다 감염 전 예방이 중요하다.

• 보건행정학회지
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• 제31권3호
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• pp.292-300
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• 2021

Background: Medication adherence in hypertension is the most important to control blood pressure and prevent major complications. The purpose of this study was to identify factors affecting medication adherence and to examine the relationship between medication adherence and blood pressure control in Korea. Methods: This study used data from the 7th Korea national health and nutrition examination survey (2016-2018) of the Korea Disease Control and Prevention Agency. We selected 4,063 hypertensive patients from the data. And we choose socio-demographic, health behavior, healthcare utilization, and severity characteristics as hypertensive patient characteristics. Results: Of the patients with hypertension, 92.3% had shown adherence to medication as of 2016-2018 and shows variation according to the characteristic of patients. The cases with male, under 50 years old, urban area, single household, unmet medical services, less than 5 years of hypertension duration, no comorbidities (diabetes mellitus, myocardial infarction) showed significantly low medication adherence. After adjusting for confounders, adherent patients tended to have lower current systolic blood pressure (β=-10.846, p<0.001) and diastolic blood pressure (β=-5.018, p<0.001) than nonadherent patients. And, adherent patients increased the control odds of blood pressure compared with nonadherent patients (odds ratio, 3.02; 95% confidence interval, 2.21-4.12). Conclusion: This study confirmed that adherence to antihypertensive drugs was effective in controlling blood pressure. In order to more actively manage hypertensive patients at the national level, it is necessary to make an effort to improve the medication compliance of nonadherent groups, such as early-diagnosis patients, young patients under 50 years of age, and patients living alone.

• Journal of Korean Neurosurgical Society
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• 제38권1호
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• pp.28-34
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• 2005

Objective : This study is performed to compare older with younger groups about clinical characteristics and overall outcome of treatments for the intracranial aneurysms. Methods : We retrospectively investigated 633 patients with cerebral aneurysms who were admitted to our institute from January 2000 to May 2004. The authors divided the patients of cerebral aneurysm into two groups, one the third, fourth decades and the other eighth, ninth decades, analyzed clinical characteristics and overall outcome of treatments. Results : There were 57 patients [9.0%] under 39years old and 58 patients [9.2%] over 70. The female to male sex ratio was 0.5 : 1 in the younger group[YG] and 7.3 : 1 in the older group[OG], showing a female predominance with increasing age. In the YG, aneurysms were found in anterior communicating artery[A-com] [44.8%], middle cerebral artery [31.0%]. In the OG, aneurysm of posterior communicating artery [30.1%] was most common followed by that of A-com [26.9%]. More smokers and alcoholics were found in the YG. Older age was related to poor Hunt-Hess grade, Fisher's grade on admission, high incidence of unruptured aneurysms, and endovascular surgery. There was a higher prevalence of hypertension, intraventricular hematoma, hydrocephalus, and rebleeding in the preoperative state in the OG and postoperative complications including hydrocephalus, subdural fluid collection, and systemic complications. Overall outcome was poorer with advancing age [p=0.01]. Conclusion : The patients with aneurysms in the YG have distinct characteristics compared to those in the OG. Because of a good clinical grade on admission, a thin subarachnoid clot, and Low incidence of perioperative complications, the overall outcomes of the young patients were better than those of the old patients.