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Antimicrobial Effects of Ethanol Extract of Yongdamgosam-hwan against Streptococcus mutans (용담고삼환(龍膽苦參丸) 에탄올 추출물의 Streptococcus mutans에 대한 항균활성에 관한 연구)

  • Yun, Yong-Il;Lee, Hae-Soo;Jung, Min-Ji;You, Seong-Il;Song, Yung-Sun;Kwon, Dong-Yeul
    • The Korea Journal of Herbology
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    • v.30 no.6
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    • pp.55-61
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    • 2015
  • Objectives : Yongdamgosam-hwan(YGH) has been used as a traditional medicine from old times for antiinflammatory effects. Streptococcus mutans(S. mutans) is known as a prime bacteria responsible for causing caries by forming a biofilm referred to as dental plaque on the tooth surface. But antimicrobial activity of YGH with dental disease is not sufficiently understood. This study was designed to investigate the effects of YGH ethanol extract on antimicrobial effect against Streptococcus mutans.Methods : The antimicrobial effect of YGH ethanol extract was assessed by the paper disk diffusion method and optical density method to determine minimum inhibition concentration(MIC), also observed by fractional inhibitory concentration index(FICI) and time-kill assay to figure out the synergic effect on the combination of YGH ethanol extract with antibiotics.Results : The YGH ethanol extract 500 μg was 7.5-8.5 mm diameter of clear zone of inhibition against Streptococcus mutans in a concentration-dependent manner and MIC was 250 μg/mL. The administration of the ethanol extract in combination with gentamicin and streptomycin induced a reduction of ≥4-8-fold in all tested bacteria. Furthermore, time-kill study was found that a combination of YGH ethanol extract with oxacillin and streptomycin produced a more rapid decrease in the concentration of bacteria CFU/mL than the YGH ethanol extract or antibiotics alone.Conclusions : As a result, the YGH ethanol extract has good antimicrobial effects. And the results suggest that YGH could be employed as a natural antibacterial agent in dental care products.

The Effect of a Au Based Bonding Agent Coating on Non-Precious Metals-Ceramic Bond Strength (비귀금속 합금에 적용한 Au Based Bonding Agent가 금속-도재 결합에 미치는 영향)

  • Lee, Jung-Hwan;Ahn, Jae-Seok
    • Journal of dental hygiene science
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    • v.9 no.4
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    • pp.405-412
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    • 2009
  • The purpose of this study investigated the effect of Au coating on adhesion between porcelain matrix and metal substructure interface. Titanium, Ni-Cr alloy and Co-Cr alloy are well known as proper metal for the dental restorations. The success of a porcelain fused to metal (PFM) restoration depends upon the quality of the porcelain-metal bond. However, adhesion between dental alloys and porcelain is related to diffusion of oxygen during ceramic firing. The excessive oxidized layers make hard adhesion between dental alloy and ceramic. Ni-Cr and Co-Cr specimens were divided into test and a control group and Titanium specimens were divided into three test groups and a control group. Each group had 20 specimens. The adhesion characteristics of porcelain and metal with Au coating layer and without Au coating layer were observed with scanning electron microscopy(SEM). The adhesion was evaluated by a biaxial flexure test and volume fraction of adherent porcelain was determined by SEM/EDS analysis. Result of this study suggest that Au coating layer is effective barrier to diffuse oxide layer completely protect non-precious alloys from oxidation during the porcelain firing. The SEM photomicrographs of cross-section specimens showed a smooth interface between Au coating layer and metals and porcelain which suggested proper chemical bonding, and no gap, porosity were observed. The mode of failure was mainly adhesive for Ti tested specimens, but mixed failures with adhesive and cohesive were observed in Ni-Cr and Co-Cr specimens. The adhesion between non-precious metals and porcelain would not be improved by Au coating agent. However, It is suggested that the continuous study is required further investigation and development.

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A Comparative Study of Aggregation Schemes for Concurrent Transmission over Multiple WLAN Interfaces (다중 무선랜 인터페이스 전송을 위한 결합 방식의 성능 연구)

  • Saputra, Yuris Mulya;Hwang, Hwanwoong;Yun, Ji-Hoon
    • Journal of the Institute of Electronics and Information Engineers
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    • v.51 no.7
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    • pp.18-25
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    • 2014
  • To increase wireless capacity, the concurrent use of multiple wireless interfaces on different frequency bands, called aggregation, can be considered. In this paper, we focus on aggregation of multiple Wi-Fi interfaces with packet-level traffic spreading between the interfaces. Two aggregation schemes, link bonding and multipath TCP (MPTCP), are tested and compared in a dualband Wi-Fi radio system with their Linux implementation. Various test conditions such as traffic types, network delay, locations, interface failures and configuration parameters are considered. Experimental results show that aggregation increases throughput performance significantly over the use of a single interface. Link bonding achieves lower throughput than MPTCP due to duplicate TCP acknowledgements (ACKs) resulting from packet reordering and filtering such duplicate ACKs out is considered as a possible solution. However, link bonding is fast responsive to links' status changes such as a link failure. It is shown that different combinations of interface weights for packet spread in link bonding result in different throughput performance, envisioning a spatio-temporal adaptation of the weights. We also develop a mathematical model of power consumption and compare the power efficiency of the schemes applying different power consumption profiles.

Cytogenetic Study of Diploid and Triploid Marine Medaka, Oryzias dancena (해산송사리, Oryzias dancena 유도 3배체의 세포유전학적 연구)

  • Park, In-Seok;Gil, Hyun Woo;Lee, Tae Ho;Nam, Yoon Kwon;Ko, Min Gyun;Kim, Dong Soo
    • Korean Journal of Ichthyology
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    • v.28 no.4
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    • pp.215-222
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    • 2016
  • Triploidy was induced in the marine medaka, Oryzias dancena by cold shock treatment ($0^{\circ}C$) of fertilized eggs for 30, 45, or 60 min, applied two minutes after fertilization. The triploid genotype was induced by each of the thermal shock regimes tested. The best result was obtained when the eggs were treated for 45 min, which induced triploidy in all the resulting fish. Triploidy was confirmed using chromosomal and flow cytometer analyses, and erythrocyte measurements. The surface areas and volumes of the erythrocytes of triploid fish were significantly larger than those of diploid fish, and their chromosome number (3N=72) was 1.5 times greater that for the diploids (2N=48). Based on a flow cytometer analysis, the triploid fish had approximately 1.5 times the cellular DNA content (2.40 pg/cell) of the diploid specimens (1.61 pg/cell). Data from this study provide the basis for the development of unique models for studying reproductive confinement in transgenic fish.

Traffic Congestion Estimation by Adopting Recurrent Neural Network (순환인공신경망(RNN)을 이용한 대도시 도심부 교통혼잡 예측)

  • Jung, Hee jin;Yoon, Jin su;Bae, Sang hoon
    • The Journal of The Korea Institute of Intelligent Transport Systems
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    • v.16 no.6
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    • pp.67-78
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    • 2017
  • Traffic congestion cost is increasing annually. Specifically congestion caused by the CDB traffic contains more than a half of the total congestion cost. Recent advancement in the field of Big Data, AI paved the way to industry revolution 4.0. And, these new technologies creates tremendous changes in the traffic information dissemination. Eventually, accurate and timely traffic information will give a positive impact on decreasing traffic congestion cost. This study, therefore, focused on developing both recurrent and non-recurrent congestion prediction models on urban roads by adopting Recurrent Neural Network(RNN), a tribe in machine learning. Two hidden layers with scaled conjugate gradient backpropagation algorithm were selected, and tested. Result of the analysis driven the authors to 25 meaningful links out of 33 total links that have appropriate mean square errors. Authors concluded that RNN model is a feasible model to predict congestion.

Structural Analysis of Related Variables of Self-Determination Among Preschoolers': Mediating Effect of Preschoolers' Self-Esteem (유아의 자기결정력 관련변인에 대한 구조분석 : 유아의 자아존중감 매개효과를 중심으로)

  • Park, Geun Joo;Seo, So Jung
    • Korean Journal of Childcare and Education
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    • v.10 no.6
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    • pp.25-42
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    • 2014
  • The primary purpose of this study was to examine the variables as related to self-determination in preschoolers. In order to meet the purpose of this study preschoolers' self-determination, their playfulness, self-regulation, and self-esteem as well as goodness of fit between mother and child were taken into account as study variables of interest. Furthermore, the mediating effect of preschoolers' self-esteem in the effects of study variables on their self-esteem was examined. Three hundred thirty seven preschooler(aged 6-7 years old)-mother pairs who attended public subsidized child care facilities, located in Seoul and Gyeongi province were sampled. The data were obtained from mother-filled surveys, and on-site observations from both head teachers of the children as well as trained researchers. The obtained data were analyzed by using SPSS 21.0, and structural equation model (SEM) was tested with AMOS 21.0. The main results of this study were in the following. First, it was proven that self-determination of the preschoolers' influenced directly or indirectly on their self-esteem, their playfulness, and self-regulation, as well as goodness of mother-child fit. Also, the result pertaining to the mediational effects of child's self-esteem in the effects of study variables of interest on the child's self-determination were revealed. Along with results of this study, there is a strong need to empower the preschoolers' self-determination through improvement of their self-esteem in early childhood education and care as well as in family settings.

Quantification and Varietal Variation of Rutin in Mulberry Fruits (뽕나무 계통별 오디함유 rutin 분석 및 품종변이)

  • Kim Hyun-bok;Kim Sun-lim
    • Journal of Sericultural and Entomological Science
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    • v.46 no.1
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    • pp.1-5
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    • 2004
  • Rutin has many beneficial effects on human health. It was established that rutin antagonizes the increase of capillary fragility associated with hemorrhagic disease, reduces high blood pressure, decreases the permeability of the vessels, and has an antiedema effect, reduces the risk of arteriosclerosis, and shows antioxidant activity. Rutin analysis with mulberry fruits was carried out by high-performance liquid chromatography (HPLC) to reveal the possibility of source of functional food. As a result, mean content of fifty accessions was 0.14±0.050% DW. Among the tested fifty accessions, 'Sabangso' was showed the highest rutin in 0.29%DW, whereas 'Simseol' was the lowest content in 0.05% DW. Also, we researched the change of rutin content according to harvested date. The rutin contents of earlier harvested groups were higher than later harvested groups. Simultaneously, fruity characteristics as well as rutin content were researched and analyzed to select the functional mulberry varieties for the production of fruit. From the six accessions which were contained high rutin content, we selected three suitable varieties such as 'Ficus', 'Kangsun', and 'Palcheongsipyung'.

Improved Performance of Direct Carbon Fuel Cell by Catalytic Gasification of Ash-free Coal (무회분탄 연료의 촉매 가스화에 의한 직접탄소연료전지의 성능 향상)

  • Jin, Sunmi;Yoo, Jiho;Rhee, Young Woo;Choi, Hokyung;Lim, Jeonghwan;Lee, Sihyun
    • Clean Technology
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    • v.18 no.4
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    • pp.426-431
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    • 2012
  • Carbon-rich coal can be utilized as a fuel for direct carbon fuel cell (DCFC). However, left-behind ash after the electrochemical oxidation may hinder the electrochemical reactions. In this study, we produced ash-free coal (AFC) by thermal extraction and then tested it as a fuel for DCFC. DCFC was built based on solid oxide electrolyte and the electrochemical performance of AFC mixed with $K_2CO_3$ was compared with AFC only. Significantly enhanced power density was found by catalytic steam gasification of AFC. However, an increase of the power density by catalytic pyrolysis was negligible. This result indicated that a catalyst activated the steam gasification reactions, producing much more $H_2$ and thus increasing the power density, compared to AFC only. Results of a quantitative analysis showed much improved kinetics in AFC with $K_2CO_3$ in agreement with DCFC results. A secondary phase of potassium on yttria-stabilized zirconia (YSZ) surface was observed after the cell operation. This probably caused poor long-term behavior of AFC with $K_2CO_3$. A thin YSZ (30 ${\mu}m$ thick) was found to be higher in the power density than 0.9 mm of YSZ.

Interdependence of Corporate Governance Mechanisms and Managers' incentive-compensation system (기업 지배구조 통제장치와경영자 유인보상제도의 상호관련성)

  • Shin, Sung-Wook
    • Management & Information Systems Review
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    • v.35 no.1
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    • pp.287-305
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    • 2016
  • This study confirms that there is a correlation between managers' incentive-compensation system(introduction of the compensation committee) and corporate governance mechanisms (ownership structure, proportion of outside directors, debt ratio, competitive strength), and analyzes whether firm value is affected by corporate governance mechanisms. The purpose of this paper are empirically tested using 318 firm-year data listed on the KRX from 2001 to 2010 and 2SLS(two-stage least square method) were used for the analysis of the hypotheses. The results of empirical tests are as follows. Firstly, there is no correlation between introduction of the compensation committee and corporate governance mechanisms. In addition, the results show that there is a causal relationship between some variables. Secondly, results from the analysis of the impact of corporate governance mechanisms on firm value, only introduction of the compensation committee and foreign investors ownership were analyzed as a positive impact on the firm value. This result means that most domestic firm don't actively used for managers' incentive-compensation system as a useful control device for improving corporate governance.

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Tax Subsidy and Information Effect of Future Earnings (조세혜택과 미래이익의 정보효과)

  • Byun, Sun-Young;Kim, Jin-Wook;Jung, Hyun-Uk
    • Management & Information Systems Review
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    • v.35 no.4
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    • pp.123-140
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    • 2016
  • This study investigates whether tax subsidy is associated with the information effect of future earnings (Future Earnings Response Coefficient, hereafter 'FERC'). Prior studies related with tax subsidy suggest that high- tax subsidy is associated with high-Conservatism. And high-tax subsidy is associated with low-information asymmetry. The hypothesis is tested by using sample firms listed on the Korean Stock Exchange from the year of 2002 to the year of 2009 inclusively. We followed methodology of Tucker and Zarowin (2006). We find that the regression coefficient for tax $subsidy{\times}X_{t3}$ shows a significant positive sign. Also, we performed additional test after controlling for variables related with FERC. The regression coefficient for tax $subsidy{\times}X_{t3}$ is consistent with main results. This result means that the changes in the current stock price of higher-tax subsidy contain more information about their future earnings than the changes in the stock price of lower-abnormal audit hours. The evidence suggests that investors positively understand high-tax subsidy.

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