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Evaluation of the Genetic Toxicity of Synthetic Chemicals (XIV)-in vitro Chromosomal Aberration Assay with 11 Chemicals in Chinese Hamster Lung Cells

  • Kim, Youn-Jung;Ryu, Jae-Chun
    • Molecular & Cellular Toxicology
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    • v.2 no.2
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    • pp.89-96
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    • 2006
  • The detection of many synthetic chemicals used in industry that may pose a genetic hazard in our environment is of great concern at present. Since these substances are not limited to the original products, and enter the environment, they have become widespread environmental pollutants, thus leading to a variety of chemicals that possibly threaten the public health. In this respect, to regulate and to evaluate the chemical hazard will be important to environment and human health. The clastogenicity of 11 synthetic chemicals was evaluated in Chinese hamster lung fibroblast cells in vitro. 1-Chloro-3-bromopropane CAS No. 109-70-6) induced chromosomal aberrations with significance at the concentration of $185.0\;{\mu}g/mL\;and\;1,600\;{\mu}g/mL$ both in the presence and absence of metabolic activation system, respectively. Triphenyl phosphite (CAS No. 101-02-0), which is one of the most cytotoxic chemical among 11 chemicals tested revealed no clastogenicity in the range of $95.0-4.9\;{\mu}g/mL$ both in the presence and absence of metabolic activation system. From the results of chromosomal aberration assay with 11 synthetic chemicals in Chinese hamster lung cells in vitro, 1-chloro-3-bromopropane revealed a positive clastogenic result in this study.

Effect of Annealing on the Mechanical properties of Fe-6.5wt% Si Alloy (Fe-6.5wt% Si 합금의 역학 특성에 미치는 어닐링 효과)

  • Yun, Yeong-Gi;Yun, Hui-Seok;Hong, Seong-Gil
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.24 no.12
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    • pp.2909-2916
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    • 2000
  • 6.5wt% Si steel is widely known as an excellent magnetic material because its magnetostriction is nearly zero. The AX magnetic properties as magnetostriction of 6.5% Si steel were evaluated and compared with those of conventional 3% Si steel sheet. In this paper, the fracture behavior of the poly crystals and single crystals of Fe-6.5wt%Si alloy has been observed. Single crystals were prepared by Floating Zone(FZ) method, which melts the alloy by the use of high temperature electron beam in pure argon gas condition. And the single crystals were annealed at 500$^{\circ}C$ and 700$^{\circ}C$ respectively and tensile tested at room temperature. According to the result, B2 phase has more good elongation than DO$_3$ phase. It was also found that the fracture surfaces of the single crystals have hairline facets in same direction, and the facets change the direction according to the single crystal phase.

A study on the improvement of the local stress field using the theory of conjugate approximations and loubignac's iterative method (공액근사개념과 Loubignac의 반복계산법을 이용한 국부응력장 개선에 대한 연구)

  • Song, Kee-Nam
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.21 no.10
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    • pp.1598-1608
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    • 1997
  • Based on the application of te theory of conjugate approximations and the Loubignac's iterative method in a local region, a method to improve the stress filed in a displacement-formulated finite element solution has been proposed. The validity of the proposed method has been tested through two examples : a thick cylinder under internal pressure loading and an infinite plate with a central circular hole subjected to uniaxial tension. As a result of analysis of the examples, it was found that the stress field obtained for the local region model by the proposed method approximates well for the whole domain model. In addition, it was found that because of a significant decrease in the computing time to obtain the improved stress field, the proposed method is efficient and useful for the detailed stress analysis in local regions.

Application of Temperature Inversion by Using Spectral Radiation Intensities (파장별 복사강도를 사용한 온도 역계산의 적용)

  • Yang, Soo-Seok;Song, Tae-Ho
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.24 no.4
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    • pp.533-542
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    • 2000
  • Analytical experiments to determine the line-of-sight temperature distribution is conducted by using spectral radiation intensities. For this study, fourteen narrow bands of $25cm^{-1}$ interval in $CO_2\;4.3{\mu}m$ band ($2,050cm^{-1}$ to $2375cm^{-1}$) are selected. The applied system is a one-dimensional gas slab filled with 100% $CO_2$ gas at 1 atm. Two types of temperature profile are tested; parabolic and boundary layer types. Three kinds of radiation calculation are used in the iteration procedure for the temperature inversion; LBL(Line by Line), SNB(Statistical Narrow Band) and WNB(WSGGM. based Narrow Band) models. The LBL solution shows perfect agreement while some error of temperature prediction is caused by radiation modeling error when using SNB and WNB models. The inversion result shows that the WNB model may be used more accurately in spectral remote sensing techniques than the traditional SNB model.

Performance of a Heat pipe with Axial Grooves Formed from Corrugated Plate (접힌 板材 로 만든 그루우브 를 갖는 熱파이프 에 관한 硏究)

  • 김태현;김기현
    • Transactions of the Korean Society of Mechanical Engineers
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    • v.9 no.1
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    • pp.47-55
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    • 1985
  • Heat pipe with axial grooves formed from corrugated plate in the adiabatic section is studied. The axial grooves made of thin corrugated plate decrease considerably the flow resistance in the adiabatic section without increasing the thermal resistance of the heat pipe, resulting in the increase of the capillary limit, especially in the cases of heat pipes that have long adiabatic section. In the theoretical analysis, it is assumed that the liquid flow in each section laminar and fully developed and Darcy's equation can be applied to each section neglecting the end-effects associated with each transitionary region. A heat pipe which consists of axially corrugated rectangular grooves in the adiabatic section and bronze mesh in the evaporator and codenser sections was made and tested. Comparison of the experimental results, using acetone as the working fluid, with the theoretical result shows satisfactory agreement.

Antitumor Activity of Health Food-C22 (건강식품 C-22의 항암 효과)

  • Jin, Wen-Yi;Yoo, Jae-Kuk;Park, Byeong-Wook;Chen, Quan-Cheng;Bae, Ki-Hwan
    • Korean Journal of Pharmacognosy
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    • v.39 no.3
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    • pp.237-240
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    • 2008
  • C-22 is one of health food made in Han Kook Shin Yak. For studying its antitumor activity, the 50% ethanol extract from C-22 was tested on BDF1 mice bearing LLC tumor cell by Teruhiro’s method. The samples were intraperitoneally injected to mice once a day with a daily dose of 50, 100, and 200 mg/kg for 14 consecutive days. Taxol was used as positive control with a dose of 50 mg/kg. As a result, the C-22's extracts dose dependently inhibited the tumor volume with the IRTV values of 28.7, 46.7, 58.9% and the IRTW values of 28.1, 46.0, 57.8% in 50, 100, and 200 mg/kg, respectively, while the Taxol showed antitumor activity with IRTV and IRTW values of 68.5 and 67.3% in 50 mg/kg. No loss of body weight was observed at any samples. This data suggested that the C-22's antitumor activity was enough to use as a cancer chemopreventive agent, and it will be used for preventing cancer as health food.

Phrase-based Topic and Sentiment Detection and Tracking Model using Incremental HDP

  • Chen, YongHeng;Lin, YaoJin;Zuo, WanLi
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.11 no.12
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    • pp.5905-5926
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    • 2017
  • Sentiments can profoundly affect individual behavior as well as decision-making. Confronted with the ever-increasing amount of review information available online, it is desirable to provide an effective sentiment model to both detect and organize the available information to improve understanding, and to present the information in a more constructive way for consumers. This study developed a unified phrase-based topic and sentiment detection model, combined with a tracking model using incremental hierarchical dirichlet allocation (PTSM_IHDP). This model was proposed to discover the evolutionary trend of topic-based sentiments from online reviews. PTSM_IHDP model firstly assumed that each review document has been composed by a series of independent phrases, which can be represented as both topic information and sentiment information. PTSM_IHDP model secondly depended on an improved time-dependency non-parametric Bayesian model, integrating incremental hierarchical dirichlet allocation, to estimate the optimal number of topics by incrementally building an up-to-date model. To evaluate the effectiveness of our model, we tested our model on a collected dataset, and compared the result with the predictions of traditional models. The results demonstrate the effectiveness and advantages of our model compared to several state-of-the-art methods.

A Study on Quality of Rice-Yackwa (쌀을 이용한 약과의 조리과학적 연구)

  • 김주희;이경희;이영순
    • Korean journal of food and cookery science
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    • v.7 no.2
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    • pp.41-49
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    • 1991
  • Yackwa is a Korean traditional fried cake made by went flour, sesame oil and honey. This study was investigated to the Rice-Yackwa for the purpose of the improvement of Yackwa's quality and rice consumption by sensory evaluation and instrumental measurement. It was resulted that taste and flavor of Rice-Yackwas were better than those of Wheat-Yackwa by sensory evaluation. We tested whether the mesh of the rice (80,100,120) and swelling agents (baking power, soju : Korean alcholic beverage) affected the Rice-Yackwa's swelling or not. In result, not by soju but by baking powder Rice-Yackwas were swelled. But Rice-Yackwa was so hard, that the Yackwas were made by the two different compositions of mixed flour (rice : wheat ; 75:25, 50:50) exibited softer than those made by rice. The hardness of 25 g% mixed flour Yackwa was improved. And we examined the softening effect on rice and mixed flour Yackwa by the increasing storage periods (1, 2, 3, 5 days). Rice-Yackwa's hardness was changed more greatly than Wheat-Yackwa's by storage periods. In addition to we inspected the effluence of sesame oil in the pross of frying. Sesame oil (40%) was drown out the Rice-Yackwa.

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Analysis of Light Environment to Turfgrass Growth under the Roof Membrane on Stadium (경기장 지붕의 막구조가 잔디생육에 미치는 광환경에 대한 영향분석)

  • Joo Young Kyoo;Lee Dong Ik;Song Kyoo D.;Shim Gyu-Yul
    • Asian Journal of Turfgrass Science
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    • v.18 no.3
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    • pp.119-128
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    • 2004
  • This study was conducted to analyze the effect of roof membrane on light environment that influence on turfgrass growth under domed stadium. Roof structure on experimental plot was constructed with PTFE and PE same as Busan Asiad Main Stadium. Tested turfgrass species were combinations of cool-season grasses(Kentucky Bluegrass, perennial ryegrass, $KBG80+PR20\%,\;KBG33+PR33+Fine fescue33\%)$ and warm-season grasses(zoysiagrass, 'An-yang middle-leaf, 'Zenith', Bermudagrass) established with seeding or sodding. The experimental set-up and research work were initiated November 1999 and finished on August 2000 at near Busan Asiad Main Stadium. By the result of computer simulation of daylight radiant energies on the turf surface were lower than needs of normal sport turf growth. The shortage of radiant resulted pest infection on cool-season grass mixture compared with warm-season. But turf color and density showed the best results on Kentucky bluegrass or its mixture plot. Over all the results showed that the best quality of turfgrass growth was occurred on full sun area, and the next was under PTFE membrane. The application of artificial lighting system may increase the turfgrass growth under domed stadium(partially) covered with roof membrane.

The Effect of Chest Meridian Massage on Post- Anesthetic Recovery of General Anesthesia Patients (흉부경락마사지가 충수돌기 절제술 환자의 마취 후 회복에 미치는 효과)

  • Lee, Byung-Yup;Shon, Kyung-Hee
    • Korean Journal of Adult Nursing
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    • v.17 no.4
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    • pp.612-621
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    • 2005
  • Purpose: This study aims at confirming the effects of the chest meridian massage on the post-anesthetic recovery of general anesthesia appendectomy patients. Method: The research was post-test designed as a nonequivalent control group among quasi-experiments tested. The data was collected from June 20, 2003 to October 14, 2003 at a hospital in P city. In the collected data, using SPSS Win 10.0 program, these general features were analyzed by real numbers and percentages; the homogeneity among variables by $X^2-test$ and t-test and the research hypothesis by the t-test. Result: Hypothesis 1; The experimental group receiving the treatment of the chest meridian massage will have a much higher post-anesthetic recovery score than that of the control group not receiving it was supported(t=2.544, p=.014). Hypothesis 2; The experimental group receiving the treatment of the chest meridian massage will have a much shorter time of stay in the recovery room than that of the control group not receiving it was supported(t=-4.919, p=.000). Conclusion: According to these results, it may be concluded that Chest Meridian Massage is effective in producing a higher level of post-anesthetic recovery score and helps appendectomy patients reduce the time of stay in the recovery room. Therefore the chest meridian massage can be considered as an intervention therapy for directly nursing general anesthesia appendectomy patients.

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