• Title/Summary/Keyword: tested result

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Correlation between mEPSC Amplitude and Rise Time upon the Blockade of AMPA Receptor Desensitization at Hippocampal Synapses

  • Jung, Su-Hyun;Choi, Suk-Woo
    • The Korean Journal of Physiology and Pharmacology
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    • v.6 no.2
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    • pp.81-85
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    • 2002
  • Conventional views of synaptic transmission generally overlook the possibility of 'postfusional-control' the regulation of the speed or completeness of transmitter release upon vesicular fusion. However, such regulation often occurs in non-neuronal cells where the dynamics of fusion-pore opening is critical for the speed of transmitter release. In case of synapses, the slower the transmitter release, the smaller the size and rate-of-rise of postsynaptic responses would be expected if postsynaptic neurotransmitter receptors were not saturated. This prediction was tested at hippocampal synapses where postsynaptic AMPA-type glutamate receptors (AMPAR) were not generally saturated. Here, we found that the small miniature excitatory postsynaptic currents (mEPSCs) showed significantly slower rise times than the large mEPSCs when the sucrose-induced mEPSCs recorded in cyclothiazide (CTZ), a blocker for AMPAR desensitization, were sorted by size. The slow rise time of the small mEPSCs might result from slow release through a non-expanding fusion pore, consistent with postfusional control of neurotransmitter release at central synapses.

Contour detection of hippocampus using Dynamic Contour Model and Region Growing (영역확장법과 동적외곽선모델을 이용한 해마(hippocampus)의 외곽선 검출)

  • Jang, D.P.;Kim, H.D.;Lee, D.S.;Kim, S.I.
    • Proceedings of the KOSOMBE Conference
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    • v.1997 no.05
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    • pp.116-118
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    • 1997
  • In hippocampal morphology Abnormalities, including unilateral or bilateral volume loss, are known to occur in epilepsy, Alzheimer's disease, and in certain amnestic syndromes. To detect such abnormalities in hippocampal morphology, we present a method that combines region growing and dynamic contour model to detect hippocampus from MRI brain data. The segmentation process is performed two steps. First region growing with a seed point is performed in the region of hippocampus and the initial contour of dynamic contour model is obtained. Second, the initial contour is modified on the basis of criteria that integrate energy with contour smoothness and the image gradient along the contour. As a result, this method improves fairly sensitivity to the choice of the initial seed point, which is often seen by conventional contour model. The power and practicality of this method have been tested on two brain datasets. Thus, we have developed an effective algorithm to extract hippocampus from MRI brain data.

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AUTOMATIC DETECTION OF EPILEPTIFORM ACTIVITY USING WAVELET AND ARTIFICIAL NEURAL NETWORK (웨이브렛과 신경회로망을 이용한 간질 파형 자동 검출)

  • Park, H.S.;Park, C.H.;Lee, Y.H.;Lee, D.S.;Kim, S.I.
    • Proceedings of the KOSOMBE Conference
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    • v.1997 no.05
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    • pp.358-361
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    • 1997
  • This paper describes a multichannel epileptic seizure detection algorithm based on wavelet transform(WT), artificial neural network(ANN) and expert system. First, through the WT, a small number of wavelet coefficients is used to represent the single channel epileptic spike. Next, 3-layer feed-forward network employing the error back propagation algorithm is trained and tested using parameters obtained above. Finally, 16 channel expert system which is based on clinical experience is introduced as a artifact rejection and reliable detection. The suggested algorithm was implemented on personal computer(PC). Two main events i.e., epileptiform and normal activities, were selected from 32 person's EEGs(normal: 20, seizure disorder: 12) in consensus among experts. The result was that WT reduced data input size and ANN detected 97 of the 100 EEGs containing definite spike - sensitivity of 97%. Expert rule system was capable of rejecting a wide variety of artifacts commonly found in EEG recordings. It also reduced false positive detections of ANN.

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Electrical and NO Conversion Characteristics of Dielectric Barrier Discharge Process (질소산화물 제거를 위한 무성 방전 공정의 전기 및 NO 전환 특성)

  • Lee, Yong-Hwan;Jeong, Jae-U;Jo, Mu-Hyeon
    • The Transactions of the Korean Institute of Electrical Engineers C
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    • v.51 no.1
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    • pp.15-21
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    • 2002
  • We investigated effects of electrical, physical, and chemical parameters on energy transfer, NO conversion, and light emission in the dielectric barrier discharge (DBD) process. As gap distance between electrodes increased, discharge onset voltage increased. However, as gap distance between electrodes increased, electric field which initiates discharge showed approximately the same value, 30kV/cm. The discharge onset voltage of the coarse surface electrode was lower than that of the smooth surface electrode. And, energy transfer was slightly enhanced in the coarse electrode condition. However, NO conversion rate decreased with the coarse surface electrode because more uniform discharge can be obtained on the smooth surface electrode. The NO conversion rate increased with decreasing the initial concentration, so the DBD process is more feasible in the lower concentration condition. The variation of gas residence time tested at the same energy density in the experiment did not affect on the NO conversion. The result shows that the NO conversion rate mainly depends on the energy density. The DBD process is able to adjust on plasma-photocatalyst process because it emits the short wavelength light in the range of ultraviolet. The intensity of light emission increased with the increase of the energy transfer to the reactor and the gas flow rate.

Application of microgravity for detecting the mineshaft (폐갱도 확인을 위한 고정밀중력탐사)

  • Rim Hyoungrae;Park Yeong-Sue;Lim Mutaek;Koo Sung Bon;Jung Hyun Key;Kim Hag Soo;Jung Chang Ho;Kwon Byoung Doo
    • 한국지구물리탐사학회:학술대회논문집
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    • 2005.05a
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    • pp.251-254
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    • 2005
  • Microgravity survey was carried out in order to detect an abandoned mineshaft. We tested the feasibility of cavity detection by means of numerical modeling and applied microgravity survey to detecting an abandoned mineshaft in the vicinity of Hawson mines, Junnam. The result shows the response of mineshaft where we expected.

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SYNTHESIS OF STEREO-MATE THROUGH THE FUSION OF A SINGLE AERIAL PHOTO AND LIDAR DATA

  • Chang, Ho-Wook;Choi, Jae-Wan;Kim, Hye-Jin;Lee, Jae-Bin;Yu, Ki-Yun
    • Proceedings of the KSRS Conference
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    • v.1
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    • pp.508-511
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    • 2006
  • Generally, stereo pair images are necessary for 3D viewing. In the absence of quality stereo-pair images, it is possible to synthesize a stereo-mate suitable for 3D viewing with a single image and a depth-map. In remote sensing, DEM is usually used as a depth-map. In this paper, LiDAR data was used instead of DEM to make a stereo pair from a single aerial photo. Each LiDAR point was assigned a brightness value from the original single image by registration of the image and LiDAR data. And then, imaginary exposure station and image plane were assumed. Finally, LiDAR points with already-assigned brightness values were back-projected to the imaginary plane for synthesis of a stereo-mate. The imaginary exposure station and image plane were determined to have only a horizontal shift from the original image's exposure station and plane. As a result, the stereo-mate synthesized in this paper fulfilled epipolar geometry and yielded easily-perceivable 3D viewing effect together with the original image. The 3D viewing effect was tested with anaglyph at the end.

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Time series Analysis of State-space Model and Multiplication ARIMA Model in Dissolved Oxygen Simulation (용존산소 농도모의시 상태공간모형과 승법 ARIMA모형의 시계열 분석)

  • 이원호;서인석;한양수
    • Journal of environmental and Sanitary engineering
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    • v.15 no.2
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    • pp.65-74
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    • 2000
  • The purpose of this study is to develop the stochastic stream water quality model for the intake station of Chung-Ju city waterworks in the Han river system. This model was based on the theory of Box-Jenkins Multiplicative ARIMA(SARIMA) and the state space model to simulate changes of water qualities. Variable of water qualities included in the model are temperature and dissolved oxygen(DO). The models development were based on the data obtained from Jan. 1990 to Dec. 1997 and followed the typical procedures of the Box-Jenkins method including identification and estimation. The seasonality of DO and temperature data to formulate for the SARIMA model are conspicuous and the period of revolution was twelve months. Both models had seasonality of twelve months and were formulates as SARIMA {TEX}$(2,1,1)(1,1,1)_{12}${/TEX} for DO and temperature. The models were validated by testing normality and independency of the residuals. The prediction ability of SARIMA model and state space model were tested using the data collected from Jan. 1998 to Oct. 1999. There were good agreements between the model predictions and the field measurements. The performance of the SARIMA model and state space model were examined through comparisons between the historical and generated monthly dissolved oxygen series. The result reveal that the state space model lead to the improved accuracy.

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Stability of Steel Frames with Weak Column-Strong Beam Considering P-Δ effect (P-Δ 효과를 고려한 기둥항복형 강구조 골조의 안정성)

  • Kim, Hee Dong;Lee, Myung Jae
    • Journal of Korean Society of Steel Construction
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    • v.15 no.4 s.65
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    • pp.457-466
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    • 2003
  • This study aimed to evaluate the stability of steel frames with weak column-strong beam and consider P-effect using the experimental approach. Towards this end, three specimens were tested under monotonic loading condition. Parameters of tests includes the stiffness of the column and the axial load ratio. Result showed that reduction in column stiffness promoted P- effect, which considerably influenced the frame's stability.

Development of a Tensile Force Measurement Device of Long Duration (인장력 상시 측정장치 개발에 관한 연구)

  • Shin, Kyung Jae;Hwang, Yun Ha
    • Journal of Korean Society of Steel Construction
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    • v.15 no.4 s.65
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    • pp.435-445
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    • 2003
  • Tension member is one of the most important elements in tension structure. An economical and reliable measurement method of a member's tensile force has yet to be developed, however. Several conventional measurement methods have some disadvantages when used for long-term, on-site measurement. A new tension-force measurement device was proposed to resolve measuring problems. Its principle was to use the bending part of the device as an elastic spring. The lateral deformation of the bending part due to tensile force can be measured to monitor the tensile force. This device was inserted in the tension member like a turn-buckle. Lateral deformation may be measured in the field at any time for the purpose of maintaining structures. Finite element analysis was used to design the shape and parametric study. Six specimens were tested within the elastic range. The test result showed that the elastic behavior or the bending part was consistent with the analysis' results.

Reduction of Simulation Number for Ship Handling Safety Assessment (선박운항 시뮬레이터 실험조건 축소화 연구)

  • Kwon, S.H.;Oh, H.S.
    • Journal of Korean Society of Industrial and Systems Engineering
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    • v.35 no.1
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    • pp.101-106
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    • 2012
  • Ship handling simulator is a virtual ship navigating system with three dimensional screen system and simulation programs. FTS simulation can produce theoretically infinite experiment tests without time constraint, but which results in collecting determinstic observations. RTS simulation can collect statistical observations but has disadvantage of spending at least 30 minutes for a single experiment. The previous studies suggested that the number of experiment conditions to be tested could be reduced to obtain random data with RTS simulation by focusing on highly difficult experiment condition for ship handling. It has the limitation of not estimating the distribution of ship handling difficulty for the route. In this paper, similarity and clustering analysis are suggested for reduction methodology of experiment conditions. Similarity of experiment conditions are measured as follows: euclidean distance of ship handling difficulty index and correlation matrix of distance differences from the designed route. Clustering analysis and multi-dimensional scaling are applied to classify experiment conditions with measured similarity into reducing the number of RTS simulation conditions. An empirical result on Dangin harbor is shown and discussed.