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Screening for Anti-inflammatory Activities in Extracts from Korean Herb Medicines (국산 생약 추출물의 항염증 활성 스크리닝)

  • An, Sang Mi;Kim, Hyoung Gun;Choi, Eun Jung;Hwang, Hyoung Hoon;Lee, Eunseok;Baek, Ji Hwoon;Boo, Yong Chool;Koh, Jae Sook
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.40 no.1
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    • pp.95-108
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    • 2014
  • Cosmetics are products used over long periods by the public, and their safety is very important. Contact dermatitis induced by cosmetics is the result of an inflammatory response of the skin to direct irritancy. The initial event that this inflammatory response is observed is the release of pro-inflammatory cytokines. In this study, the anti-inflammatory activities of extracts from Korean herb medicines were investigated using RAW264.7 macrophage. Among the fifty one extracts tested, the ethanol extracts from Biotae Orientalis Folium, Biotae Orientalis Folium (roasted), Cyperi Rhizoma, Nepetae Spica, Benincasae Semen, Dioscoreae Rhizoma, Dioscoreae Rhizoma (roasted), Mori Ramulus, Pini Ramulus and Alismatis Rhizoma reduced the cytotoxicity and inhibited the productions of Nitric oxide (NO) and cytokines such as interleukin (IL)-1${\beta}$, IL-6 and tumor necrosis factor (TNF)-${\alpha}$n lipopolysaccharide (LPS)-induced RAW264.7 macrophage. Additionally, they didn't induce the skin irritation when tested the human patch test. Overall, the result of this study suggests that the extracts of the ten Korean herb medicines are useful cosmetic agents for preventing the skin irritation.

Investigation into Bonding Characteristics of Tack Coat Materials for Asphalt Overlay on Concrete Pavement (콘크리트포장 위 아스팔트 덧씌우기용 택코팅 재료의 접착강도특성 연구)

  • Cho, Mun Jin
    • International Journal of Highway Engineering
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    • v.15 no.4
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    • pp.85-94
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    • 2013
  • PURPOSES: The performance of tack coat, commonly used for layer interface bonding, is affected by application rate and curing time. In this study, bonding strength tests were performed according to the application rate and curing time of asphalt emulsion. Based on finding from this study, optimum application rates and curing times are proposed. METHODS: In order to investigate bonding characteristic of asphalt emulsion, tests were performed on both asphalt concrete pavement and portland concrete pavement. Also, asphalt emulsions were tested at the application rate of 0, 0.2, 0.4, 0.6, and $0.8{\ell}/m^2$ and at the curing time of 0, 0.5, 1, 2, and 24 hours. Pull-off test and shear bonding strength test, which commonly used for bonding strength measurement of asphalt emulsion, were adopted for this study. To assess field performance under different testing condition, asphalt emulsions were applied to in-service pavement. Throughout coefficient of determination analysis between material index properties from asphalt emulsion and mechanical response from bonding strength tests, performance correlativity was analyzed. RESULTS: Test results show that optimum application rate for asphalt overlay on asphalt concrete pavement (AOA) and asphalt overlay on concrete pavement (AOC) was $0.4{\sim}0.5{\ell}/m^2$ and $0.3{\sim}0.5{\ell}/m^2$, respectively. According to the curing time increment, tensile strength and shear strength of AOC were increased to 22~44% and 20~39%, respectively. AOA case also show strength increment in tensile strength (42%) and shear strength (9%). We tested the applicability of tack coat materials at the field sites, and our findings demonstrated that the bonding (for D and E) and rapid curing (for B, C, and D, E) performances were superior than others. Among material index properties, there was a high correlation between penetration ratio and bonding strength test result. CONCLUSIONS : Result show that interlayer bonding strength was affected by asphalt emulsion type, application rate and curing time. AOC required slightly higher application ($0.1{\ell}/m^2$) than AOA. Both AOA and AOC cases show higher strength at longer curing time. Up to 2hours of curing, rapid strength increments were observed, but strength increment ratio was decreased after 2hours of curing. From the observed correlation between penetration ratio and bonding strength, it is expected that penetration ratio can be used as one of important factors affecting bonding strength analysis.

Study on the Promotion Effect of Ionic Liquid on CH4 Hydrate Formation (이온성 액체를 이용한 메탄 하이드레이트 생성 촉진효과 연구)

  • Shin, Ju-Young;Kim, Kisub;Kang, Seong-Pil;Mun, Sungyong
    • Korean Chemical Engineering Research
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    • v.51 no.4
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    • pp.500-505
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    • 2013
  • In this study, we investigated the kinetics of gas hydrate formation in the presence of ionic liquid (IL). Hydroxyethyl-methyl-morpholinium chloride (HEMM-Cl) was chosen as a material for the promotion effect test. Phase equilibrium curve for $CH_4$ hydrate with aqueous IL solution was obtained and its induction time and consumed amount of $CH_4$ gas were also measured. Aqueous solutions containing 20~20,000 ppm of HEMM-Cl was prepared and studied at 70 bar and 274.15 K. To compare the measured results to those of the conventional promoter, sodium dodecyl sulfate was also tested at the same condition. Result showed that the hydrate equilibrium curve was shifted toward higher pressure and lower temperature region. In addition, the induction time on $CH_4$ hydrate formation in the presence of IL was not shown. The amount of consumed $CH_4$ was increased with the whole range of tested concentration of IL and the highest consumption of $CH_4$ happened at 1,000 ppm of HEMM-Cl. HEMM-Cl induced and enhanced the $CH_4$ hydrate formation with a small amount of addition. Obtained result is expected to be applied for the development of technologies such as gas storage and transport using gas hydrates.

Improving the Accuracy of 3D Object-space Data Extracted from IKONOS Satellite Images - By Improving the Accuracy of the RPC Model (IKONOS 영상으로부터 추출되는 3차원 지형자료의 정확도 향상에 관한 연구 - RPC 모델의 위치정확도 보정을 통하여)

  • 이재빈;곽태석;김용일
    • Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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    • v.21 no.4
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    • pp.301-308
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    • 2003
  • This study describes the methodology that improves the accuracy of the 3D object-space data extracted from IKONOS satellite images by improving the accuracy of a RPC(Rational Polynomial Coefficient) model. For this purpose, we developed the algorithm to adjust a RPC model, and could improve the accuracy of a RPC model with this algorithm and geographically well-distributed GCPs(Ground Control Points). Furthermore, when a RPC model was adjusted with this algorithm, the effects of geographic distribution and the number of GCPs on the accuracy of the adjusted RPC model was tested. The results showed that the accuracy of the adjusted RPC model is affected more by the distribution of GCPs than by the number of GCPs. On the basis of this result, the algorithm using pseudo_GCPs was developed to improve the accuracy of a RPC model in case the distribution of GCPs was poor and the number of GCPs was not enough to adjust the RPC model. So, even if poorly distributed GCPs were used, the geographically adjusted RPC model could be obtained by using pseudo_GCPs. The less the pseudo_GCPs were used -that is, GCPs were more weighted than pseudo_GCPs in the observation matrix-, the more accurate the adjusted RPC model could be obtained, Finally, to test the validity of these algorithms developed in this study, we extracted 3D object-space coordinates using RPC models adjusted with these algorithms and a stereo pair of IKONOS satellite images, and tested the accuracy of these. The results showed that 3D object-space coordinates extracted from the adjusted RPC models was more accurate than those extracted from original RPC models. This result proves the effectiveness of the algorithms developed in this study.

A Study on the Properties & Application for High-Calcium Fly Ash (고칼슘 플라이애쉬의 특성 및 활용방안에 관한 연구)

  • Won, Cheol;Lee, Sang-Soo;Kwon, Yeong-Ho;Ahn, Jae-Hyen;Park, Chil-Lim
    • Magazine of the Korea Concrete Institute
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    • v.7 no.5
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    • pp.155-163
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    • 1995
  • The primary purpose of this study is to hvestigate reusal techniques of high calclun-i fly ash in the construct.ion field, which may contribute to the savings of construction materials and consenratlng environment. Furt.hcrrnore, it can setup material properties or characteristics requiremi for development of new materials. Firstly, chemical and physical cahraci.eristics of liigh~calciurn fly ash is arialyseti. And then, the usability of the concrete is tcsted by investigating the flowablility and strength development through parameters of various replace ment r,itios with respect to different nuxing conditions. Finally, the durability and mechanical properties(e1astic nlodulus of the concrete is tested. As the result of the study, the following conclusions are derived : (1) the quaritii y of the CaO The primary purpose of this study is to hvestigate reusal techniques of high calclun-i fly ash in the co:lstruct.ion field, which may contribute to the savings of construction materials and consenratlng environment. Furt.hcrrnore, it can setup material properties or characteristics requiremi for development of new materials. Firstly, chemical and physical cahraci.eristics of liigh~calciurn fly ash is arialyseti. And then, the usability of the concrete is tcsted by investigating the flowablility and strength development through parameters of various replace ment r,itios with respect to different nuxing conditions. Finally, the durability and mechanical properties(e1astic nlodulus of the concrete is tested. As the result of the study, the following conclusions are derived : (1) the quaritii y of the CaO

A Study on Photovoltaic Panel Monitoring Using Sentinel-1 InSAR Coherence (Sentinel-1 InSAR Coherence를 이용한 태양광전지 패널 모니터링 효율화 연구)

  • Yoon, Donghyeon;Lee, Moungjin;Lee, Seungkuk
    • Korean Journal of Remote Sensing
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    • v.37 no.2
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    • pp.233-243
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    • 2021
  • Photovoltaic panels are hazardous electronic waste that has heavy metal as one of the hazardous components. Each year, hazardous electronic waste is increasing worldwide and every heavy rainfall exposes the photovoltaic panel to become the source of heavy metal soil contamination. the development needs a monitoring technology for this hazardous exposure. this research use relationships between SAR temporal baseline and coherence of Sentinel-1 satellite to detected photovoltaic panel. Also, the photovoltaic plant detection tested using the difference between that photovoltaic panel and the other difference surface of coherence. The author tested the photovoltaic panel and its environment to calculate differences in coherence relationships. As a result of the experiment, the coherence of the photovoltaic panel, which is assumed to be a permanent scatterer, shows a bias that is biased toward a median value of 0.53 with a distribution of 0.50 to 0.65. Therefore, further research is needed to improve errors that may occur during processing. Additionally, the author found that the change detection using a temporal baseline is possible as the rate of reduction of coherence of photovoltaic panels differs from those of artificial objects such as buildings. This result could be an efficient way to continuously monitor regardless of weather conditions, which was a limitation of the existing optical satellite image-based photovoltaic panel detection research and to understand the spatial distribution in situations such as photovoltaic panel loss.

Toxin Gene and Antibiotic Resistance of Staphylococcus aureus and Bacillus cereus Isolated from Indoor Air in Cafeteria (급식실 실내공기에서 분리된 황색포도상구균과 바실러스 세레우스의 독소 유전자 및 항생제 내성)

  • Oh, Do-Gyung;Jo, Ah-Hyeon;Kim, Chan-Yeong;Jeong, Eun-Sun;Kim, Jung-Beom
    • Journal of Food Hygiene and Safety
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    • v.36 no.6
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    • pp.520-527
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    • 2021
  • In this study, toxin gene and antibiotic resistance of food poisoning strains isolated from indoor air in the cafeteria were analyzed to prevent food poisoning. Staphylococcus aureus (16 strains) and Bacillus cereus (37 strains) isolated from indoor air in child care center were tested. The toxin genes of S. aureus and B. cereus were detected by PCR assay. The antimicrobial susceptibility test followed the disc diffusion method described by the Clinical and Laboratory Standard Institute. The seg and sei toxin genes were detected in 11 of 16 S. aureus strains (68.6%). The nheA and nheB toxin genes were detected in 37 B. cereus strains. In this study, a total of 12 toxin gene patterns of B. cereus were found, among which the nheA-nheB-nheC toxin gene was found to be the most frequent pattern. The result of the antimicrobial susceptibility test of S. aureus revealed 93.8% and 87.5% resistance to ampicillin and penicillin antibiotics, but methicillin resistance S. aureus and vancomycin resistance S. aureus were not detected. All 37 B. cereus tested in this study were resistant to ampicillin and penicillin antibiotics. Based on the result of this study, it was judged that regular ventilation and air quality management were necessary to prevent food poisoning caused by S. aureus and B. cereus contaminated in the indoor air of child care centers.

Growth and Yield of Forage Rice Cultivar 'Yeongwoo' according to Nitrogen Application Amount in Reclaimed Paddy Field

  • Eun-Ji Song;Sun-Woong Yun;Ji-Hyeon Mun;In-Ha Lee;Su-Hwan Lee;Nam-Jin Chung
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.67 no.4
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    • pp.326-334
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    • 2022
  • This study was carried out to investigate the optimal nitrogen concentration level suitable for forage rice growth by hydroponic cultivation in the salinity concentration of 0.1~0.3% which is similar to that of Muan reclaimed paddy field, and based on this results, to estimate optimal nitrogen fertilization level by field experiment in Muan reclaimed paddy for maximum forage production by cultivation of Yeongwoo rice. As a result of the growth response to the salt and nitrogen concentrations in the hydroponic cultivation experiment, the growth amount increased as the nitrogen concentration increased in the range of 0~24 me/L in the absence of salt stress. However, at a salt concentration of 0.1~0.3%, the growth amount was the highest at a nitrogen concentration of 12 me/L, and at higher nitrogen concentrations of that, the rice growth decreased as the nitrogen concentration increased. Therefore, nitrogen concentration of 12 me/L was judged to be an appropriate concentration for forage rice growth at salt concentration of 0.1~0.3%, and a nitrogen fertilization amount level corresponding to a nitrogen concentration of 12 me/L was actually applied to the Muan reclaimed paddy field for forage rice cultivation during two years. The amount of nitrogen fertilizer was tested with three treatments, which are 18 kg/10a considered appropriate, and 1.5 times and 2 times of the appropriate amount, and the planting density was tested with 2 treatments of 15 hills/m2 and 26 hills/m2. As a result of the reclaimed paddy field experiment, the yield was the highest when nitrogen fertilizer was applied at 18 kg/10a in the planting density of both treatments. Looking at the yield according to planting density, the high planting density plot yielded higher than the low planting density plot. In other words, when the planting density was 26 hills/m2 and the nitrogen fertilization amount was 18 kg/10, the highest dry matter yield of 1,763 kg/10a was obtained. From the results of hydroponics and reclaimed field experiments, we could conclude that the productivity of forage rice decreased more as the nitrogen concentration increased when the nitrogen concentration was higher than the optimal level under salt stress.

The Effect of Influencer Characteristics on Continuous Use Intention of Live Commerce : Focusing on the Dual Mediating Effect of Interaction and Trust (라이브 커머스 인플루언서 특성이 지속 사용의도에 미치는 영향 : 상호작용성과 신뢰성의 이중매개효과를 중심으로)

  • Kim, Sung-jong;Chung, Byoung-gyu
    • Journal of Venture Innovation
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    • v.5 no.4
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    • pp.23-39
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    • 2022
  • This study was conducted to empirically analyze the factors influencing the intention to continue using live commerce, which was active as digital contacts become more prevailed due to the progress of the 4th industrial revolution and the COVID-19 pandemic. A research model was established by paying attention to the characteristics of influencers among various influencing factors. Influencer characteristics were subdivided into attractiveness, professionality, awareness, and entertainment. In addition, the dual mediating effect of interaction and trust was also tested between influencer's characteristics and the intention to continue using of live commerce. To this end, a survey was conducted targeting people who have experience using live commerce, and 300 valid samples were analyzed. The empirical analysis utilized SPSS 25.0 and Process Macro 4.0. As a result of the empirical analysis, it was found that attractiveness, professionality, awareness, and entertainment derived from the characteristics of influencers all had a significant positive (+) effect on the intention to continue using live commerce. The impact of the influence of variables that directly affect the intention to continue using was in the order of entertainment, awareness, professionality, and attractiveness. On the other hand, as a result of examining the dual mediating effect of interaction and trust, it was found that they all tested a mediating role between attractiveness, professionality, awareness, entertainment, and intention to continue using live commerce. Based on these research results, the academic and practical implications of this study were presented.

The Physical Properties of Polymer Concrete for Ultra Thin Bridge Deck Pavement (초박층 교면포장용 폴리머 콘크리트의 물리적 특성)

  • Kim, Hyeon Jun;Son, Yeong Hyo;Han, Bum Jin;Jung, Ji Eun;Park, Sun Kyu
    • Journal of the Korea institute for structural maintenance and inspection
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    • v.17 no.3
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    • pp.74-81
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    • 2013
  • This research was performed to identify physical properties of polysulfide epoxy polymer concrete for ultra-thin bridge deck pavement, and improve domestic applicability. With the optimum mix ratio determined from mixing experiments of polymer concretes, compressive, flexural, and bond strength were tested to identify its strength properties along with the freezing-thawing resistance test to evaluate its durability in harsh environments. As a result, the tested polymer concretes showed excellent performance in strength and deflection characteristic and all tested strength satisfied the criteria of American Concrete Institute. Moreover, it had better performance under variable temperatures comparing to other existing pavement materials. By the results of freezing-thawing resistance test and strength measurement for specimens underwent the freezing-thawing process, it can be judged that there is no such problem to the concrete's durability. In conclusion, the newly developed polymer concrete in this research has appropriate properties for use in ultra-thin pavement on bridge deck, and moreover it has superior applicability in comparison with former materials due to its improved temperature sensitivity.