• 한국방사선학회논문지
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• 제17권5호
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• pp.767-773
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• 2023

본 연구에서는 폐용적에 영향을 미치는 관련 인자들과 폐기능 환기장애에 대한 유의성을 평가하고자 하였다. 실험대상으로는 저선량 흉부 CT검사와 폐활량검사를 동시에 수행한 정상 성인 남·여 206명을 선정하였으며 실험방법으로는 저선량 흉부 CT검사로 획득한 폐 CT 영상을 이용하여 폐용적을 딥러닝 기반의 AVIEW LCS 자동진단 프로그램을 이용하여 측정하였다. 그리고 폐활량계를 이용하여 폐기능을 측정한 결과를 획득하였으며 폐용적에 영향을 미치는 관련 인자로 성별 및 BMI를 선정하여 폐용적과의 독립표본 T-test를 통하여 유의성을 평가하고자 하였다. 실험결과 성별에 따른 폐용적의 평가에서 남성의 모든 폐용적이 여성의 모든 폐용적보다 크다는 것을 확인할 수 있었다. 성별 및 폐용적에 대한 각각의 평균값을 이용한 독립표본 T-test 결과 남성이 여성보다 모든 폐용적이 더 크다는 결과는 유의한 결과를 나타내었다(p<0.001). 그리고 BMI 지수에 따른 폐용적의 평가에서 BMI 지수 24 이상의 성인의 모든 폐용적이 BMI 지수 24 미만의 모든 폐용적보다 크다는 것을 확인할 수 있었다. 그러나 BMI 지수 및 폐용적에 대한 각각의 평균값을 이용한 독립표본 T-test 결과 BMI 지수 24 이상이 BMI 지수 24 미만보다 모든 폐용적이 더 크다는 결과는 유의한 결과를 나타내지 않았다(p<0.055). 폐기능 환기장애 유무에 따른 폐용적의 평가에서 폐기능 환기 정상성인의 모든 폐용적이 폐기능 환기 장애성인의 모든 폐용적보다 크다는 것을 확인할 수 있었다. 그리고 폐기능 환기장애 유무 및 폐용적에 대한 각각의 평균값을 이용한 독립표본 T-test 결과 폐기능 환기 정상성인이 폐기능 환기 장애성인보다 모든 폐용적이 더 크다는 결과는 유의한 결과를 나타내었다(p<0.001). 폐용적과 폐활량 검사 결과는 폐 건강을 평가하는데 가장 중요한 지표이며, 이 두 지표를 함께 사용하여 폐 기능을 평가하는 것이 가장 정확한 평가 방법이다. 그러므로 본 연구에서는 폐용적과 폐활량 검사에 대한 향후 유사 연구 시 폐기능 환기 정상 성인과 폐기능 환기 장애 성인에 대한 폐용적 평균값을 제시하여 기초자료로 활용될 것이라고 사료된다.

• 대한임상검사과학회지
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• 제41권1호
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• pp.1-5
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• 2009

The Platelet Function Analyzer (PFA)$^{(R)}$-100 measures the ability of platelets activated in a high-shear environment to occlude an aperture in a membrane treated with collagen and epinephrine (CEPI) or collagen and ADP (CADP). The time taken for the flow across the membrane to stop (closure time, CT) is recorded. The aim of this study was to assess the potential of the PFA$^{(R)}$-100 as a primary clinical screening tool using the wide spectrum of clinical samples assessed for platelet function as well as to perform the optimal algorithm for the use of PFA$^{(R)}$-100. We established the reference interval in 460 hospital inpatients defined as having normal platelet function based on classical laboratory tests. The reference interval by using the range $5^{th}$ and $95^{th}$ percentile was 84~251 seconds for males CEPI-CT and 85~249 seconds for females CEPI-CT. A total of 1,200 inpatients were enrolled to identify impaired hemostasis before surgical interventions. The abnormal group showing prolonged CEPI-CT was 303 cases (18.9%). Only 3 cases had both abnormal CEPI-CT and CADP-CT. Several factors including sample errors, drugs, hematologic abnoralities were contributed to unexpected prolonged CEPI-CT for screening test. The von Willebrand factor (vWF:Ag) assay was performed only in one patient to verify the algorithm for the use of PFA$^{(R)}$-100. The PFA$^{(R)}$-100 was sensitive and rapid method for primary screening test of platelet dysfunction, so we can substitute it for the bleeding time in routine clinical practice.

• 한국임상보건과학회지
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• 제1권1호
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• pp.75-82
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• 2013

Purpose : The aim of this study was to identify the relation of cognition and visuospatial perception in stoke patients. Methods : A total of 16 stroke patients recruited from two hospital located in Donghae, Kang-won participated in this study(Right hemiplegia : twelve, Left hemiplegia : four). All participants scored higher than 20 point on the MMSE-K. To assess the cognitive function, we performed the Korean version of Mini Mental State Examination(MMSE-K), spatial perception domain of Lowenstein Occupational Therapy Cognition Assessment(LOTCA), Figure Color Copy(FCC), Linebisection Test(LBT) and Albert's test in stoke patients. Results: The Korean version of Mini Mental State Examination and spatial perception domain of Lowenstein Occupational Therapy Cognition Assessment were the highest points in sixty ages, Figure Color Copy is difference between Right hemiplegia and Left hemiplegia. Linebisection Test(LBT) and Albert's test had much relation, visuospatial perception had not relationship. Conclusion: Aging was cognition function and visuospatial perception had an interrelationship. visuospatial perception according to affected side in brain had an interrelationship but cognition function and visuospatial perception had not any interrelationship.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• 제21권3호
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• pp.147-152
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• 2010

Objectives : The purpose of this study was to investigate the deficits in executive function in children with ADHD and anxiety disorder, and further, to characterize executive function deficits among the two groups. Methods : Subjects consisted of 60 children between the ages of 5 and 14 (16 Normal, 24 ADHD, 20 Anxiety Disorder). Neuropsychological tests (KEDI-WISC, CCTT, STROOP, WCST, ROCF) for assessing cognitive and executive function were individually administered to all subjects. Results : There were no significant differences in FSIQ or PIQ among the three groups. However, the ADHD group tended to score lower on the VIQ and subtest of similarity, vocabulary, and digit span tests. The three groups did not significantly differ with respect to CCTT test results. On the STROOP test, the ADHD group showed poor performance on the word, color, and color-word subtests. The three groups did not exhibit significant differences in WCST test results ; however, the anxiety group performed poorly belonging to below 25 percentile rank on perseverative response. On the ROCF test, the ADHD group performed poorly with respect to their organization score and in particular, regarding copy and immediate recall. The anxiety group also performed poorly with regard to organization ; however, this was limited only to immediate recall. Conclusion : Children with ADHD displayed poor inhibition and organizational abilities compared to children with anxiety and normal controls. Further, children with anxiety disorder exhibited low cognitive flexibility and voluntary problem-solving abilities compared to ADHD children and normal controls. Based on these results, we suggest that the characteristics of executive dysfunction in ADHD and anxiety disorder in children are different.

• 동의생리병리학회지
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• 제23권5호
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• pp.1080-1086
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• 2009

This study was designed to investigate the effects of Gastrodiae Elata Pharmacopuncure at GB20 on motor control and cognitive dysfunction recovery after mild traumatic brain injury in rats. Rats were divided into three groups; (1) no treatment after traumatic brain injury(experiment I), (2) Treatment with NPA after traumatic brain injury(experiment II), (3) Treatment with GEP after traumatic brain injury(experiment III). In our study, we carried out behavioral test(Rotarod, Morris water maze) and immunohistochemistry study of the change BDNF in the hippocampus(pre, $7^{th}$, $14^{th}$ day). In Rotarod test(motor control function) was significantly increased in the experimental group III as compared with experimental group I, II on $7^{th}$(p<0.01) and $14^{th}$ day(p<0.001). In Morris water maze test(cognitive function) was significantly decreased in the experimental group III as compared with experimental group I, II on $14^{th}$ day(p<0.001). In immunohistochemistric response of BDNF in the hippocampus, the experimental group III was more immune response than the other groups on $14^{th}$ day. These results imply that Gastrodiae Elata Pharmacopuncure at GB20 can play a role in facilitating recovery of motor control and cognitive function after mild traumatic brain injury in rats.

• 성인간호학회지
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• 제20권2호
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• pp.209-218
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• 2008

Purpose: Regarding the respiratory function of patients with an artificial airway, this study compared the effects between normal saline with chest vibration and normal saline with expectorant mixture, administered before endotracheal suction. Methods: The study was conducted in the ICUs of one university hospital located in Incheon. The experimental group I received normal saline with chest vibration administered before endotracheal suction while the experimental group II received normal saline with expectorant mixture administered before endotracheal suction. For respiratory function, $PaO_2$, $PaCO_2$, and $O_2$ saturation were measured by ABGA at 3 minutes after endotracheal suction for both pre-test and post-test. Results: The two groups were not different significantly regarding $PaO_2$ level and $O_2$ saturation after the treatments, while, the experimental group II had lower $PaCO_2$ level than the experimental group I after the treatments (t = 2.075, p = .042). For experimental group II, post-test score of $PaCO_2$ level was significantly lower than that of the pre-test score (t = 1.842, p = .075). Conclusion: The administration of normal saline with expectorant mixture before endotracheal suction reduced $PaCO_2$ level and improved the respiratory function.

• 대한통합의학회지
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• 제8권3호
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• pp.21-31
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• 2020

Purpose : The purpose of this study was to determine the effects of a cognitive-exercise program using step on the cognitive function, gait, and depression of elderly with mild cognitive impairment. Methods : The subjects comprised 30 elderly people with mild cognitive impairment who used elderly welfare centers in the provinces A, B, and C between March 21 and June 7, 2019. They were divided into an experimental group (n=15) and a control group (n=15) before undergoing an experiment based on a pretest-posttest control group design. The lowenstein occupational therapy cognitive assessment-geriatric population was used to assess the subjects' cognitive function, while the 4-stage balance test, 30-second chair-stand test, timed up & go test, and functional reach test were employed to evaluate their gait. In addition, the beck depression inventory was used to measure their levels of depression. Results : The cognitive-exercise program using step enhanced the subjects' cognitive function and gait and reduced their levels of depression. Furthermore, statistically significant differences were found between the experimental group and the control group. Conclusion : The cognitive-exercise program using step promoted the process of sensorimotor and cognition through the learning process of various steps taking left and right steps and cognitive activities. It improves gait by activating the coordination of the musculoskeletal and nervous systems of the body and positively affecting posture control, balance, flexibility, and lower extremity muscles. It also relieved depression by performing successful step learning and cognitive activities with forward-looking (doing) that leads to pleasure and achievement. The present study confirmed the value of a cognitive-exercise program using step to treat multiple domains of functional decline in elderly patients with mild cognitive impairment. This is therefore proposed as an intervention program for this patient group.

• 한국구조물진단유지관리공학회 논문집
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• 제14권6호
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• pp.124-131
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• 2010

록볼트는 주변 지반의 지보 기능을 유리하게 활용하기 위한 부재로서 일반적으로 소요의 강도 이상을 가진 강재로 된 이형봉강을 활용하고 있다. 그러나, 부식성 요소가 많은 지하수 조건에서는 강재의 부식으로 인한 록볼트의 파괴로 터널 및 사면안정의 보수, 보강 및 유지관리 문제가 많이 발생하게 된다. 이러한 문제를 해결하고 영구적으로 사용가능한 터널 지보재로 활용하기 위한 실질적인 거동을 모사하여 GFRP 록볼트의 거동에 대한 실험적 평가를 실시하였다. 이 연구는 GFRP 록볼트의 인장성능 평가시험 및 전단성능 평가시험을 통해 도출된 GFRP 록볼트의 구조적 특성을 바탕으로 구조해석을 통한 사면안정해석을 실시하여 안전율을 평가하였다. 실험 결과 기존에 사용하던 강재 록볼트의 대체 재료로서 충분히 터널 지반의 안정성을 확보 할 수 있을 것으로 판단된다.

• PNF and Movement
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• 제17권2호
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• pp.199-206
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• 2019

Purpose: The purpose of this study was to evaluate the effects of a virtual upper extremity training program using the RAPAEL Smart Glove on upper extremity function in stroke survivors with chronic hemiparesis and to focus the training program development using the Smart Glove as a feasibility study. Methods: This study was conducted using a single group and pre-post test research design in the outpatient departments of local rehabilitation units. Ten chronic hemiparetic stroke survivors with a diagnosis of first stroke received therapeutic rehabilitation at the rehabilitation units. All the participants used a virtual reality program with the RAPAEL Smart Glove for 30 minutes per session 3 days a week over 8 weeks. They also received conventional occupational therapy with functional electrical stimulation for 40 minutes per session 3 days a week for 8 weeks as an additional therapy. To analyze the effects of this therapeutic intervention, four clinical measures, including the box-block test (BBT), the Wolf motor function test (WMFT), the trail-making score, the Jebsen Taylor hand function test (JTHFT), and grip strength, were used. Results: Upon completion of the intervention in week 8, all the participants demonstrated significant WMFT, JTT, BBT, grip strength, and trail-making score gains compared to the respective baselines at week 0. Conclusion: This study suggests that virtual upper extremity training using the RAPAEL Smart Glove has a reasonable and beneficial effects on upper extremity function in chronic hemiparetic stroke survivors.

• Physical Therapy Rehabilitation Science
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• 제11권1호
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• pp.32-42
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• 2022

Objective: This study was conducted to verify the effectiveness of a cognitive rehabilitation program consisting of physical exercises and mental activities for patients with chronic stroke with mild cognitive impairment (MCI). We aimed to investigate how this cognitive rehabilitation program affects patients' cognitive ability, depression, and sleep quality. Design: One group pretest-posttest design Methods: The study was conductedon 12 patients who participated in thecognitive rehabilitation complex exercise program for 16 weeks. The Korean version of the Montreal Cognitive Assessment (MoCA-K), Hamilton Depression Rating Scale (K-HDRS), and Pittsburgh Sleep Quality Index (PSQI) were used to evaluate the measured variables before and after study participation. The cognitive rehabilitation complex exercise program included 30 minutes of cognitive exercise and 30 minutes of Brill Exercise. The Wilcoxon signed-rank test was used to compare the variables before and after program participation. Cronbach's ɑ was used to assess the reliability of the test variables. Results: The post-program assessment showed a statistically significant increase in the MoCA-K score, which measures cognitive function (Z=-2.628, P=0.009). For depression ratings, there was a statistically significant decrease in the K-HDRS score (Z=-2.041, P=0.041). For sleep quality, although there was a numerical increase in the PSQI score, the difference was not statistically significant (Z=-0.702, P=0.483). The reliability test confirmed that all the individual test variables exhibited high reliability (cognitive function, 0.859; depression, 0.872; sleep, 0.822). Conclusions: We found that cognitive rehabilitation program used in this study had a positive effect on the cognitive function and depression in patients with chronic stroke with MCI.