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Effects of Combined Cognitive and Physical Exercise Program on Cognitive and Physical Functions in Older Adults with Mild Cognitive Impairment

  • Hyungyu Cha;Hyeyeon Shim;Geonwoo Kim;Seunghoon Bae;Changmin Lee;Youngjun Choi;Wonjae Choi
    • Physical Therapy Rehabilitation Science
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    • v.13 no.1
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    • pp.43-52
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    • 2024
  • Objective: This study aimed to investigate the impact of a 12-week combined cognitive and physical exercise program on cognitive and physical functions in older adults diagnosed with mild cognitive impairment (MCI). Design: A one-group pretest-posttest study. Methods: Twelve participants with MCI engaged in a weekly 60-minute session of combined cognitive and physical exercise program. Cognitive function was assessed using the Montreal Cognitive Assessment (MoCA), while physical function was evaluated through measures of muscle strength, postural balance, and walking capabilities. Muscle strength assessments included the arm curl test, handgrip strength, and the 5 sit-to-stand test. Postural balance was evaluated using the one-leg stance test, timed up-and-go test, functional reach test, and four square step test. Walking function was analyzed through a gait analysis device. Pre- and post-intervention measurements were compared to determine the effects of the exercise program. Results: The results demonstrated significant improvements in MoCA, arm curl test, timed up-and-go test, walking speed, and cadence following the 12-week intervention (p<0.05). MoCA scores revealed enhanced cognitive performance, while measures of muscle strength, including the arm curl test, exhibited significant changes. Improvements in timed up-and-go test scores indicated enhanced mobility, accompanied by increased walking speed and cadence, as evidenced by gait analysis. Conclusions: This study suggests that a structured 12-week program incorporating both cognitive and physical exercises can lead to meaningful improvements in cognitive and physical functions among older adults with MCI.

Neuroprotective Effects of Sopung-tang(Shufeng-tang) on Cognition and Motor Function Recovery after Ischemic Brain Injury in Rats (소풍탕이 허혈성 뇌손상 흰쥐의 인지 및 운동기능회복에 미치는 효과)

  • Chu, Min-Gyu;Choi, Jin-Bong;Shin, Mi-Suk;Kim, Sun-Jong
    • Journal of Korean Medicine Rehabilitation
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    • v.18 no.2
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    • pp.45-60
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    • 2008
  • Objectives : Sopung-tang(Shufeng-tang) is a famous herbal prescription that treated ischemic brain injury. This study was designed to evaluate the effects of Sopung-tang(Shufeng-tang) on congnition and motor function recovery after ischemic brain injury in rats. Methods : Male rats were divided into 4 groups. Those rats caused ischemic brain injury by occlusion of MCA as Longa method. Control group I was per os normal saline for 7 days after ischemic brain injury. Control group II was per os normal saline for 14 days after ischemic brain injury. Experimental group I(Ex I) was taken with Sopung-tang(Shufeng-tang) for 7 days after ischemic brain injury. Experimental group II(Ex II) was taken with Sopung-tang(Shufeng-tang) for 14 days after ischemic brain injury. The author carried out neurological, cognitive motor behavior tests and histological assessment. Neurological motor behavior tests consist of limb placement test, beam-walking test and horizontal wire test. Morris water maze test was used for cognitive motor behavior test. In the histological assessment test, TTC(2,3,5-triphenylteterazolium chloride) staining, Hematoxylin & Eosin staining and immunohistochemical staining were experimented. Results : 1. In neurological motor behavior tests, motor function recovery was significantly increased in the experimental groups as compared with control groups(p<0.05). Especially Ex II was significantly increased as compared with Ex I(p<0.05). 2. In Morris water maze test, congnitive motor function recovery was significantly increased in the experimental groups as compared with control group(p<0.05). Especially Ex II was significantly increased as compared with Ex I(p<0.05). 3. In the immunohistochemical staining for the expression of BDNF in hippocampus, more immune reaction was investigated in the experimental groups as compared with control groups. Especially most immune reaction was experimented in the EX II. Conclusions : According to the above results, Sopung-tang(Shufeng-tang) can treat on the congnition and motor function recovery after ischemic brain injury in rats. And it is effective method in expression of BDNF in hippocampus.

Factors Related to Balance Ability in Healthy Elderly (노인의 균형유지 능력에 영향을 미치는 요인)

  • Kim, Won-Ho;Yi, Chung-Hwi;Chung, Bo-In;Cho, Sang-Hyun
    • Physical Therapy Korea
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    • v.5 no.3
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    • pp.21-33
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    • 1998
  • The purposes of this study were to ascertain differences of the sensory system, central processing system, effector system, and balance ability according to general characteristics (sex, fall experience, and age), and to identify the contributions of the sensory, central processing, and effector system to balance ability in 83 healthy elderly subjects. The subjects were elderly (over 60 years) who live in Wonju City. All subjects participated in six tests (position sense test, visual acuity, vestibular stepping test, Mini-Mental Status Exam-Korea, strength of dorsiflexors, and Berg Balance Test). Collected data were analyzed by the independent t-test, one-way ANOVA, and stepwise multiple regression. The results were as follows: 1. The results of the six tests according to sex showed that vestibular function was significantly better in women than in men. But visual acuity, cognitive function, strength of dorsiflexors, and balance ability were significantly better in men than in women (p<0.05). 2. There were no significant differences in position sense, visual acuity, vestibular function, cognitive function, strength of dorsiflexors, and balance ability between fallers and non-fallers (p>0.05). 3. However, the results of the six tests according to age (group A: 60-69 years, group B: 70-79 years, group C: 80-89 years) showed significant differences in five tests. In the Scheff$\acute{e}$ test, position sense, visual acuity, and cognitive function showed significantly different results between in group A and group C: the strength of the dorsiflexors was significantly different between in group A and group B, and balance ability was significantly different between in group A and group C, and between in group B and group C (p<0.05). 4. Cognitive function and position sense were positively associated with balance ability. Their power of explanation regarding balance ability was 38% (p<0.05). These results suggest that cognitive function and position sense play an important role in balance ability. This would seem to suggest that programs for evaluation or improvement of elderly's balance ability in the elderly should consider cognitive function and position sense.

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A Clinical Study of the Effects of Chungganhaeju-tang on Alcoholic Fatty Liver (청간해주탕이 알코올성 지방간에 미치는 영향에 대한 임상적 연구)

  • 이장훈;박신명;김영철;우흥정
    • The Journal of Korean Medicine
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    • v.22 no.4
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    • pp.107-113
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    • 2001
  • Objectives : The aim of this study was to investigate effects of Chungganhaeju-tang on alcoholic fatty liver. Methods : Thirty patients with alcoholic fatty liver were included in this study. Chungganhaeju-tang was administered to subjects for 1 month. The changes of clinical symptoms and chemical liver function tests were evaluated before and after treatment. Results : Chungganhaeju-tang has effects on the improvement of clinical symptoms such as fatigue, anorexia, dyspepsia, nausea, and RUQ (Right Upper Quadrant) pain. On the chemical liver function test, serum AST, ALT, GGT, and TG level significantly decreased (P<0.05, by paired t-test). Conclusions : These results suggest that Chungganhaeju-tang has significant effects on the improvement of clinical symptoms and chemical liver function test with alcoholic fatty liver.

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On simple estimation technique for the reliability of exponential lifetime model

  • Al-Hemyari, Z.A.;Al-Saidy, Obaid M.;Al-Ali, A.R.
    • International Journal of Reliability and Applications
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    • v.14 no.2
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    • pp.79-96
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    • 2013
  • Exponential distribution plays a key role in engineering reliability and its applications. The exponential failure model has been studied for years. This article introduces two new preliminary test estimators for the reliability function (R(t)) in complete and censored samples from the exponential model with the use of a prior estimation (${\theta}_0$) of the mean (${\theta}$). The proposed preliminary test estimators are studied and compared numerically with the existing estimators. Computer-intensive calculations for bias and relative efficiency show that for, different values of levels of significance and for varying constants involved in the proposed estimators, the proposed estimators are far better than classical and existing estimators.

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Influencing Factors of Mentoring on Nursing Students (멘토링의 영향요인: 간호대학생을 대상으로)

  • Seol-Young Bang
    • Journal of the Korean Society of Industry Convergence
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    • v.26 no.5
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    • pp.733-741
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    • 2023
  • The purpose his study was a descriptive research study to identify the influencing factors of mentoring for nursing students, and was conducted with 120 nursing students. The collected data were subjected to real number and percentage, mean and standard deviation, t-test, ANOVA, Scheffe test, Pearson's correlation, and multiple regression analysis using SPSS/WIN 25.0. As a result of the study, mentoring was found to have a significant positive correlation with organizational socialization, core nursing competency, and clinical performance competency, and the explanatory power of the regression model was 64.1%. Since mentoring is an effective teaching method, based on this study, we propose a study to develop a structured mentoring program including organizational socialization, core nursing competency, and clinical performance competency to test the effectiveness. In addition, proposes a study to identify the relationship with various variables by dividing mentoring into sub-competencies of career development function, psychological stability function, and role model function.

Effects on Salivation, Xerostomia and Halitosis in Elders after Oral Function Improvement Exercises (입체조가 노인의 타액분비량, 구내건조증 및 구취에 미치는 영향)

  • Kim, Young Jin;Park, Kyung Min
    • Journal of Korean Academy of Nursing
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    • v.42 no.6
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    • pp.898-906
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    • 2012
  • Purpose: The purpose of this study was to investigate effects of Oral Function Improvement Exercises on salivation, xerostomia and halitosis in elderly people. Methods: The participants in the study were 48 female community-dwelling elders in D city. The Oral Function Improvement Exercises were given 3 times a week, for a total of 24 times from August to October 2011. Spitting method, Visual Analogue Scale, and halimeter (mBA-21) were used to evaluate the effects of Oral Function Improvement Exercises on salivation, xerostomia, and halitosis. The data were analyzed using ${\chi}^2$-test and t-test with the SPSS program. Results: The experimental group had significantly better salivation, and less xerostomia and halitosis than the control group. Conclusion: The results indicate that Oral Function Improvement Exercises were effective for salivation, xerostomia and halitosis in the elders. Therefore, it was suggested that Oral Function Improvement Exercise are applicable in a community nursing intervention program to improve the quality of life for elders.

Relationship of Family Strengths, Family Function, Ego-Identity and Depression in Adolescence (청소년이 지각한 가족 건강성, 가족 기능, 자아정체감과 우울과의 관계)

  • Bae, Kyung-Eui;Kim, Eun-Ha
    • Child Health Nursing Research
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    • v.13 no.3
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    • pp.357-366
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    • 2007
  • Purpose: This study was conducted to survey and examine the relationship of family strengths, family function, ego-identity and depression in adolescence in Busan, and to provide basic data for a health promoting intervention to improve their family health. Method: Data were collected from four colleges in Busan and, 680 students were enrolled in the study. Descriptive statistics, t-test or ANOVA with Scheffe's test and Pearson's correlation coefficients were used to analyze the data. Results: The mean score for family strengths was 3.58, family function 4.31, ego-identity 55.4 and depression 17.9. The scores for family strengths differed significantly according to subjective social economic state and father's job, parent's religion, parent's marital status and family composition. The scores for family function differed significantly according to parent's religion, parent's marital status and subjective social economic state. The scores for ego-identity differed according to mother's education level, parent's religion, parent's marital status and family composition. There were a positive correlations between family strengths and family function, between family strengths and ego-identity, between family function and ego-identity. There were negative correlations between family strengths and depression, between family function and depression, between ego-identity and depression. Conclusion: In order to promote ego-identity and to decrease depression in adolescence, it is necessary to develop supporting interventions to develop family strengths.

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Cognitive Function in Non-Insulin Dependent Diabetic Patients (인슐린 비의존성 당뇨병 환자의 인지기능)

  • Jung, Mi-Ha;So, Hee-Young
    • The Korean Journal of Rehabilitation Nursing
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    • v.8 no.1
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    • pp.38-49
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    • 2005
  • Purpose: The purpose of this study was to examine the cognitive function in NIDDM patients. Method: The data were collected at MI OPD in C University hospital. with Digit Span Forward & Backward, Trail Making Test-A, Trail Making Test-B, and MMSE. Result: There were significant differences in DF, DB, TMT-A, and TMT-B according to gender, and in TMT-A according to living with spouse and comorbidity. There were significant differences in DF, DB, TMT-A, TMT-B, and MMSE according to monthly income, and in DF, TMT-A, and TMT-B according to hypertensive state. But, there was no difference in cognitive function score according to diabetes-related complication and diabetes treatment modality. There was a significant positive correlation between duration of NIDDM and TMT-A(r=.215, p=.025). The global cognition score was explained 42.1% of varient by age, duration of education, monthly income, and hypertensive state. Conclusion: As above results showed, among age, duration of education, monthly income, and hypertensive state, prevented and managed hypertensive state which is modifiable factor may reduce or delay cognitive function impairment in NIDDM patients. And DF & DB, TMT-A & B could be more utilized as useful cognitive function measurements because those tests reflected cognitive function in NIDDM patients better than MMSE.

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The Effects on the Pulmonary Function and Body Mass Index of 20's Men Obesity after Treadmill Exercise (트레드밀 훈련이 20대 남성 비만인의 폐기능 및 체질량지수에 미치는 영향)

  • Seo, Kyochul;Kim, Hyeonae
    • Journal of The Korean Society of Integrative Medicine
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    • v.4 no.4
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    • pp.13-19
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    • 2016
  • PURPOSE : The purpose of this study was to determine whether tredmill exercise increases pulmonary function and decreases body mass index of the 20s obesity. METHOD : Thirty obesity in their 20s were randomly assigned to on experimental group (n=15) or control group (n=15). Over the course of four weeks, the experimental group participated in tredmill exercise for 30 minutes three times per week and the control group participated in auto-med exercise for 30 minutes three times per week. Subjects were assessed pre-test and post-test by measurement of pulmonary function (tidal volume, inspiration reserve volume, expiratory reserve volume, vital capacity) and body mass index. RESULT : Our findings show that the experimental group had significant difference in expiratory reserve volume and vital capacity and body mass index (p<.05). In the comparison of the two groups, the experimental group had higher pulmonary function and lower body mass index than the control group. CONCLUSION : In this study, the experimental group showed greater improvement in pulmonary function than the control group, which indicates that the tredmill exercise is effective at increasing the pulmonary function and body mass index 20s obesity.