• 한국콘텐츠학회논문지
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• 제14권7호
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• pp.550-558
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• 2014

본 연구의 목적은 학생들의 자가학습을 기반으로 한 활동을 소개 적용하고, 이에 대한 학습자의 태도를 알아보는데 있다. 본 연구는 충청도 권에 위치한 A 대학교에서 실시하였으며, 총 28명의 학생이 참여하였다. 본 연구에서 제시된 과업녹음활동은 McCormick과 Vercellotti(2013), Stillwell, Curabba, Alexander, Kidd, Kim, Stone과 Wyle(2010)의 활동을 수정 보완하여 제시하였다[14][19]. 과업녹음활동의 3단계는 준비단계, 과업녹음활동단계, 그리고 평가단계로 구성되었다. 연구방법으로 설문지와 학생저널이 사용되었고, 질적으로 수집, 분석되었다. 본 연구의 결과로 과업녹음활동은 의사소통 위주의 수업뿐만 아니라 시험기반의 토익스피킹수업에서도 적용가능하며, 학생들 또한 토익스피킹 과업 학습에 있어서 자가전사와 자가수정에 긍정적인 태도를 보였다. 본 연구의 시사점으로 시험기반의 수업에서 과업녹음활동은 학생들을 자기주도적인 학습자로 나아가는데 도움을 줄 수 있으며, 학생들의 영어능숙도에 따른 가이드라인을 제공함으로써 학습에 대한 자가성찰 활동을 발전시킬 수 있을 것이다. 이때, 학생들은 스스로의 학습에 대한 적극적인 태도가 필요할 것이다.

• 한국간호교육학회지
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• 제5권2호
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• pp.285-299
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• 1999

The Effect of Curriculum with voluntary program on Self-Actualization in Nursing Students. The purpose of this study was to identify the effect of the voluntary program experience with curriculum on self-actualization in nursing college students and to guide the desirable voluntary activity of college students. The research design utilized in this study was one group pretest-posttest design. The data were gathered two times with self-actualization test. First data were gathered before voluntary activity. And second data were gathered after instruction and five times voluntary activity. The data were analized by frequency, t-test, paired t-test and ANOVA using the SAS program. The results were as follows: The scores of self-actualization in nursing students belonged to normal range. Before voluntary activity, the scores were significantly higher than standardized group in Nature of Man, Constructive Scale (P<.001), and the scores were significantly lower than standardized group in Feeling Reactivity Scale(P<.05) and Capacity for Intimate Construct Sscale (P<.001). After the activity the scores were significantly higher than standardized group in Self Actualizing Values Scale(P<.001), Existentiality (P<.01), Spontaneity Scale (P<.001). Self Acceptance Scale(P<.05) and Nature of Man, Constructive Scale (P<.001). After the activity the scores were significantly increased more than before the activity in Inner Directed Scale (P<.001). Self Actualizing Values Scale (P<.001), Feeling Reactivity Scale (P<.001), Capacity for Intimate Construct Sscale (P<.001). Spontaneity Scale (P<.01), Time Competent Scale (P<.05) and Existentiality (P<.05). And the scores were not significantly increased more than before the activity in Self Regard Scale, Self Acceptance Scale and Nature of Man, Constructive Scale. The results of this study showed that voluntary activities were effective self-actualization. So, it is thought that voluntary program is necessary in the curriculum for nursing college students. This study suggests as follows : 1) It is necessary to inspect the self-actualization test after various experience of voluntary activity in college students. 2) It is necessary to grope the plans to activate the social service programs. 3) It is necessary to study continious and voluntary social service of college students.

• 근관절건강학회지
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• 제20권2호
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• pp.102-111
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• 2013

Purpose: This study was conducted to examine the effects of a fall prevention education on the fall-related knowledge, prevention activity of the elderly hospitalized in internal medicine department. Methods: A nonequivalent control group pretest-posttest design was used for this study. A total of 44 patients of the elderly hospitalized in internal medicine department were randomly divided into the experimental group (n=22) and the control group (n=22). The experimental group received about an half hour, fall prevention education at the admission day, 3days and 5days after admission, while the control group received the usual care. The outcome variables were measured before and after fall prevention education. Data were analyzed with $x^2$-test and t-test by using SPSS 12. Results: The experimental group showed significant improvement in fall-related knowledge and prevention activity. Conclusion: The fall prevention education was effective in increasing fall-related knowledge and prevention activity of the elderly hospitalized in internal medicine department. For reducing fall events, it is important to educate the elderly hospitalized about fall-related knowledge and prevention activity related to fall.

• 생명과학회지
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• 제10권5호
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• pp.524-528
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• 2000

택사(Alismatis Rhizoma)는 중국에서 많이 생산되고, 우리나라에서도 그 생산량의 50%이상이 전남 순천지방에서 생산되고 있는데, 옛부터 생약으로 많이 사용되어 왔으며, 최근 택사분말은 무좀에 도포약으로 쓰이고 있어 택사에는 다양한 생리활성이 있는 것으로 생각된다. 따라서 본 연구에서는 추출용매에 따른 택사 추출물에 대한 항균 및 항산화성에 대하여 조사하였다. Paper disc법에 의한 택사 추출물의 항균 test결과 물추출물에서는 거의 모든 시험균주에서 항균활성이 나타났으나, 메탄올 및 에탄올 추출에서는 그 활성이 작게 나타났으며, 시험균주중 Vibrio parahaemolyticus균에 가장 강한 항균활성을 나타내었다. Linoleic acid에 대한 항산화력의 조사에서 택사 물추출물 100$\mu{l}$첨가시 메탄올 및 에탄올 추출물은 항균효과 나타나지 않았고, 물추출물은 효과가 나타났으나 0.1% BHT첨가시 보다는 그 효과가 적었다.

• 한국미생물·생명공학회지
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• 제27권1호
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• pp.15-22
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• 1999

Various lactic acid bacteria were isolated from Korean Kimchi in order to study their antimutagenic substances. Ames test using Salmonella typhimurium TA98 and TA100 showed the strain KLAB21 to have the highest antimutagenic activity among the 230 isolated strains against MNNG (N-methyl-N'-nitro-N-nitrosoguanidine), NPD (4-nitro-O-phenylenediamine), NQO (4-nitrosoquinoline-1-oxide) and AFB1 (aflatoxin B1). The strain was identified as Lactobacillus plantarum based on its morphological, cultural and physiological characteristics. Antimutagenic activity of L. plantarum KLAB21 was found in culture supernatant suggesting the bacterium secrete antimutagenic substance in the media. No mutagenic activity was found in the culture supernatant. The isolated strain L. plantarum KLAB21 showed much higher antimutagenic activity than L. plantarum IAM1261 which is being used industrially for fermented milk production. The antimutagenic activity of L.plantarum KLAB21 was reconfirmed by the spore-rec assay using spores of Bacillus subtilis H17($Rec^+$) and M45($Rec^-$).

• 한국미생물·생명공학회지
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• 제20권1호
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• pp.1-5
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• 1992

유백피 추출물의 항세균 효과를 측정하기 위해 각각 다른 농도의 추출물의 함유한 배지에서 MIC를 측정하고, 증식에 미치는 영향을 조사한 결과는 다음과 같았다.이 추출물은 실험에서 사용된 세균 중 S.aureus, S.epidermidis, S.faecalis, B.subtilis, M.luteus와 같은 그람 양성균 및 E.coli, S.typhi, P.vulgaris, P.aeruginosa와 같은 그람 음성균에서 높았고, K.pneumoniae에 대해서는 항균력을 나타내지 않았다. 이 추출물 중의 항세균 효과를 가진 물질은 $121^{\circ}C$에서 20분간 멸균한 후에도 항세균 효과에는 별다른 변화가 없었다.

• 대한본초학회지
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• 제21권2호
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• pp.47-53
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• 2006

Objectives : This study was conducted to determine if Scutellaria baicalensis can be used in cosmetic emulsion cream for patients with atopic dermatitis. Methods : Scutellaria baicalensis extract was obtained with the use of butylene glycol through the pressurized solvent extraction(PSE). The antioxidative activity was assessed through SOD-like activity measurement and skin irritating potential was tested using human patch test. Antimicrobial activity was measured by the clear zone formed against Staphylococcus aureus and Escherichia coli and the rheological effects on the emulsion creams were examined using oscillation test. Results : The SOD-like activity increased dose-dependently and was about 90% at 1,000ppm of Scutellaria baicalesis extract. And Scutellaria baicalensis extract did not show any potential to be irritating to the human skin, but it could not be used as an antimicrobial agent for its poor antimicrobial activity against Staphylococcus aureus. The complex modulus decreased by 1,000 pascals and the loss angle also decreased by 20% with the addition of Scutellaria baicalensis extract into the cosmetic emulsion creams, that is, the extract can confer more elastic property on the vehicle. Conclusion : From those results, Scutellaria baicalensis extract can be effectively used as an antioxidant and reinforces the elastic skincare film formed by the application of cream for patients with atopic dermatitis.

• 분석과학
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• 제36권1호
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• pp.44-52
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• 2023

This protocol clarifies a simple and precise method for measuring the activity of xanthine oxidase (XO) enzyme inhibitor. XO enzyme, which accelerates oxidative stress-related disorders through its capacity to generate hydrogen peroxide and superoxide anion radicals (O₂^•-), has been found to be inhibited by several plant extracts. Enzyme samples were incubated with a suitable buffer containing adequate amounts of xanthine as a substrate to determine XO activity. The method depends on direct measurements of uric acid and hydrogen peroxide production to test XO with and without interference. The CUPRAC reagent (Cu(Nc)₂²⁺) was used to inhibit enzyme reaction after incubation was complete. The generated urate and peroxide reduced the Cu(II)-neocuproine complex (Cu(Nc)₂²⁺) to a brightly colored Cu(I)-neocuproine complex (Cu(Nc)₂⁺), which was assessed with a spectrophotometer at 450 nm. XO activity was found to be directly related to the increased absorbance of the colored Cu(I)-neocuproine complex (Cu(Nc)₂⁺). To eliminate catalase enzyme interference, the proposed method used sodium azide and was validated against XO activity using the UV method in matched samples with t-test analysis. The proposed assay can determine XO activity with high precision, as indicated by the correlation coefficient (R² = 0.9935) from comparison with the reference protocol.

• 한국학교보건학회지
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• 제30권2호
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• pp.146-153
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• 2017

Purpose: The purpose of this study was to identify the association between physical activity and vitamin D deficiency status among Korean adolescents. Methods: This is cross-sectional analysis of Korean adolescents aged 10-18 years from the 5th Korea National Health and Nutrition Examination Survey(KNHANES 2010-2012; n=2,384). We estimated the prevalence of vitamin D deficiency and identified the correlations with the strength of physical activity. $x^2$ test, t-test, and multiple logistic regression using complex sample analysis were done. The odds ratio of vitamin D deficiency by physical activity was calculated using complex sample multivariate logistic regression analysis. Results: The prevalence of vitamin D deficiency was 78.2%. The mean serum 25 (OH) D level in deficiency group and non-deficiency group was 14.4ng/mL, 23.7ng/mL respectively. Differences by age strata (the prevalence ranging from 68.5% to 86.3%) and gender (78.6% for boy and 84.5% for girl) were identified. Among adolescents aged 16-18 or girl in vigorous physical activity, a significant correlation between vitamin D deficiency and physical activity was observed, whereas no significant correlation were found among adolescents in moderate physical activity. Conclusion: In conclusion, vigorous physical activity was associated with vitamin D deficit in Korean adolescents. Thus, intervention programs enhancing vigorous activity than moderate activity need to be developed in schools and community.

• 대한본초학회지
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• 제22권4호
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• pp.51-58
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• 2007

Objectives : Investigation of the memory and cognitive enhancing effect of HT008-1 in scopolamine induced amnesia mice. Methods : At 60 min before acquisition trials, HT008-1 (30, 100, 300 mg/kg p.o.) was administered, and 30 min later, mice were injected with scopolamin (1.0 mg/kg, i.p.). In the passive avoidance test, acquisition trials were carried out 30 min after a single scopolamine treatment. Retention trials were carried out 24h after acquisition trials. Y-maze test was carried out 30 min after a single scopolamine treatment. Spontaneous alternation behavior during an 8-min session was recorded. Inhibitory effects of HT008-1 (0.01, 0.1, 1.0 mg/ml) on AChE activity was measured. Result : HT008-1 ameliorated scopolamine-induced learning impairments and spatial cognitive function in passive avoidance and Y-maze test, respectively. Moreover HT008-1 showed a significant inhibitory effect on AChE activity. Discussion: This study presented that eMultiherb mixture HT008-1 enhanced learning memory and spatial cognitive function in scopolamine-induced amnesia mice. These results suggest that the effect of HT008-1 may be dependent on the inhibition of AChE activity.