• Applied Chemistry for Engineering
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• v.29 no.3
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• pp.350-355
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• 2018

In this study, the effect of biomass torrefaction on the thermal and catalytic pyrolysis of cork oak was investigated. The thermal and catalytic pyrolysis behavior of cork oak (CO) and torrefied CO (TCO) were evaluated by comparing their thermogravimetric (TG) analysis results and product distributions of bio-oils obtained from the fast pyrolysis using a fixed bed reactor. TG and differential TG (DTG) curves of CO and TCO revealed that the elimination amount of hemicellulose in CO increased by applying the higher torrefaction temperature and longer torrefaction time. CO torrefaction also decreased the oil yield but increased that of solid char during the pyrolysis because the contents of cellulose and lignin in CO increased due to the elimination of hemicellulose during torrefaction. Selectivities of the levoglucosan and phenolics in TCO pyrolysis oil were higher than those in CO pyrolysis oil. The content of aromatic hydrocarbons in bio-oil increased by applying the catalytic pyrolysis of CO and TCO over HZSM-5 ($SiO_2/Al_2O_3=30$). Compared to CO, TCO showed the higher efficiency on the formation of aromatic hydrocarbons via the catalytic pyrolysis over HZSM-5 and the efficiency was maximized by applying the higher torrefaction and catalytic pyrolysis reaction temperatures of 280 and $600^{\circ}C$, respectively.

• Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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• v.31 no.6_1
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• pp.471-481
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• 2013

Recently, the frequency of debris flow disaster has increased, which is one of the natural disasters during extremely heavy rainfall condition. This paper described the analysis method about deposition characteristics of debris flow using topographic characteristics of debris flow path. First, we observed topographic changes by differencing high- resolution LiDAR DEMs acquired before and after the occurrence of debris flow event. We assumed that deposition on outside of debris flow path was generated by movements due to the inertia of debris flows. Then, we analyzed three topographic characteristics of debris flow path: slope in flow direction, transition angle of flow path, and the net efficiency(L/H) of debris flows defined by the ratio of transport length(L) and elevation difference(H). We applied this method to Umyeon Mountain debris flow event in July 2011. The results showed that deposition on outside of debris flow path due to the inertia of debris flows was significantly related to the transition angle of debris flow path. Also, we figured out that there were more frequent such depositions in locations where the ratio of 'transition angle / (L/H)' is over 8.

• Journal of Society of Preventive Korean Medicine
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• v.24 no.1
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• pp.1-14
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• 2020

Objectives : The purpose of this systematic review was to investigate the efficacy and safety of Sanjoin-tang (Suanzaoren decoction, SZRD) for insomnia in menopausal syndromes. Method : We searched the following databases: PubMed, Cochrane Library, EMBASE, China National Knowledge Infrastructure (CNKI), Chinese Science and Technique Journals Database (VIP), Wanfang, Research Information Service System (RISS), OASIS, Korean studies Information Service System (KISS), and National Digital Science Library (NDSL) databases. Randomized controlled trials (RCTs) or quasi-RCTs that used SZRD for women in menopause were included. The methodological quality of each RCT was assessed using the risk of bias tool. Results : In total, nine RCTs were finally included. The included RCTs had a high risk of bias across their domains. Three RCTs examined the effects of SZRD compared with western medicine (WM) in insomnia. Three RCTs showed favorable effects of SZRD with insomnia. Infrastructure also showed that SZRD resulted in better clinical WM (RR 1.19, 95% CI 1.07 to 1.32, P=0.001, I²=0%). Four RCTs showed favorable effects of Modified SZRD with insomnia. Infrastructure also showed that Modified SZRD resulted in better clinical WM (RR 1.13, 95% CI 1.04 to 1.23, P=0.004, I²=0%). Among the 4 RCTs, three RCTs showed an equivalent effect on the total Pittsburh Sleep Quality Index (PSQI). The meta-analysis also showed that Modified SZRD had a superior effect on the total of PSQI (total of PSQI : MD -2.55, 95% CI -3.72 to -1.37, P<0.0001, I²=85%). Only 2 trials reported adverse events and none reported severe adverse events. Conclusion : SZRD appears to be safe, but there is insufficient evidence to make a definitive conclusion because only a few studies reported adverse events. Due to the poor methodological quality of the included studies and the small number of trials included, the evidence cannot be reproduced and assessed. Well-designed RCTs with a larger sample size are needed in the future.

• Biomolecules & Therapeutics
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• v.24 no.4
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• pp.363-370
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• 2016

Cardiovascular disease is the most common cause of death in diabetic patients. Hyperglycemia is the primary characteristic of diabetes and is associated with many complications. The role of hyperglycemia in the dysfunction of human cardiac progenitor cells that can regenerate damaged cardiac tissue has been investigated, but the exact mechanism underlying this association is not clear. Thus, we examined whether hyperglycemia could regulate mitochondrial dynamics and lead to cardiac progenitor cell dysfunction, and whether blocking glucose uptake could rescue this dysfunction. High glucose in cardiac progenitor cells results in reduced cell viability and decreased expression of cell cycle-related molecules, including CDK2 and cyclin E. A tube formation assay revealed that hyperglycemia led to a significant decrease in the tube-forming ability of cardiac progenitor cells. Fluorescent labeling of cardiac progenitor cell mitochondria revealed that hyperglycemia alters mitochondrial dynamics and increases expression of fission-related proteins, including Fis1 and Drp1. Moreover, we showed that specific blockage of GLUT1 improved cell viability, tube formation, and regulation of mitochondrial dynamics in cardiac progenitor cells. To our knowledge, this study is the first to demonstrate that high glucose leads to cardiac progenitor cell dysfunction through an increase in mitochondrial fission, and that a GLUT1 blocker can rescue cardiac progenitor cell dysfunction and downregulation of mitochondrial fission. Combined therapy with cardiac progenitor cells and a GLUT1 blocker may provide a novel strategy for cardiac progenitor cell therapy in cardiovascular disease patients with diabetes.

• Biomolecules & Therapeutics
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• v.26 no.6
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• pp.546-552
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• 2018

A comprehensive collection of proteins senses local changes in intracellular $Ca^{2+}$ concentrations ($[Ca^{2+}]_i$) and transduces these signals into responses to agonists. In the present study, we examined the effect of sphingosine-1-phosphate (S1P) on modulation of intracellular $Ca^{2+}$ concentrations in cat esophageal smooth muscle cells. To measure $[Ca^{2+}]_i$ levels in cat esophageal smooth muscle cells, we used a fluorescence microscopy with the Fura-2 loading method. S1P produced a concentration-dependent increase in $[Ca^{2+}]_i$ in the cells. Pretreatment with EGTA, an extracellular $Ca^{2+}$ chelator, decreased the S1P-induced increase in $[Ca^{2+}]_i$, and an L-type $Ca^{2+}$-channel blocker, nimodipine, decreased the effect of S1P. This indicates that $Ca^{2+}$ influx may be required for muscle contraction by S1P. When stimulated with thapsigargin, an intracellular calcium chelator, or 2-Aminoethoxydiphenyl borate (2-APB), an $InsP_3$ receptor blocker, the S1P-evoked increase in $[Ca^{2+}]_i$ was significantly decreased. Treatment with pertussis toxin (PTX), an inhibitor of $G_i$-protein, suppressed the increase in $[Ca^{2+}]_i$ evoked by S1P. These results suggest that the S1P-induced increase in $[Ca^{2+}]_i$ in cat esophageal smooth muscle cells occurs upon the activation of phospholipase C and subsequent release of $Ca^{2+}$ from the $InsP_3$-sensitive $Ca^{2+}$ pool in the sarcoplasmic reticulum. These results suggest that S1P utilized extracellular $Ca^{2+}$ via the L type $Ca^{2+}$ channel, which was dependent on activation of the $S1P_4$ receptor coupled to PTX-sensitive $G_i$ protein, via phospholipase C-mediated $Ca^{2+}$ release from the $InsP_3$-sensitive $Ca^{2+}$ pool in cat esophageal smooth muscle cells.

• Journal of the Korean Vacuum Society
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• v.22 no.6
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• pp.321-326
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• 2013

The effect of rapid thermal annealing (RTA) on the optical properties of digital-alloy InGaAlAs multiple quantum well (MQW) structures have been investigated by using photoluminescence (PL) and time-resolved PL measurements as a function of RTA temperature. The MQW samples were annealed from $700^{\circ}C$ to $850^{\circ}C$ for 30 s in a nitrogen atmosphere. The MQW sample annealed at $750^{\circ}C$ exhibited the strongest PL intensity and the narrowest FWHM (Full width at half maximum), indicating the reduced nonradiative recombination centers and the improved interfaces between the wells and barriers. The MQW samples annealed at $800^{\circ}C$ and $850^{\circ}C$ showed the decreased PL intensities and blueshifted PL peaks compared to $750^{\circ}C$-annealed sample. The blueshift of PL peak with increasing RTA temperatures are ascribed to the increase of aluminum due to intermixing of gallium (Ga) and aluminum (Al) in the interfaces of InGaAs/InAlAs short-period superlattices. The decrease of PL intensity after annealing at $800^{\circ}C$ and $850^{\circ}C$ are attributed to the interface roughening and lateral composition modulation caused by the interdiffusion of Ga and Al and indium segregation, respectively. With increasing RTA temperature the PL decay becomes slower, indicating the decrease of nonradiative defect centers. The optical properties of digital-alloy InGaAlAs MQW structures can be improved significantly with optimum RTA conditions.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.29 no.7
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• pp.550-559
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• 2018

The effectiveness of deep neural networks (DNNs) for detection and classification of micro-Doppler signals generated by human walking and background noise sources is investigated. Previous research included a complex process for extracting meaningful features that directly affect classifier performance, and this feature extraction is based on experiences and statistical analysis. However, because a DNN gradually reconstructs and generates features through a process of passing layers in a network, the preprocess for feature extraction is not required. Therefore, binary classifiers and multiclass classifiers were designed and analyzed in which multilayer perceptrons (MLPs) and DNNs were applied, and the effectiveness of DNNs for recognizing micro-Doppler signals was demonstrated. Experimental results showed that, in the case of MLPs, the classification accuracies of the binary classifier and the multiclass classifier were 90.3% and 86.1%, respectively, for the test dataset. In the case of DNNs, the classification accuracies of the binary classifier and the multiclass classifier were 97.3% and 96.1%, respectively, for the test dataset.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.20 no.11
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• pp.527-536
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• 2019

This study examines the degradation of PTT BCF and fading behavior of disperse dye by heat treatment and UV irradiation. The behavior in strength degradation of PTT BCF after treat treatment was examined by measuring the tensile strength of samples. The strength retention of PTT BCF rapidly decreased with increasing exposure time at 150℃. The K/S value decreased with increasing temperature and its trend accelerated with increasing exposure time on heat. The behavior on strength degradation of PTT BCF and the fading of disperse dye on it were studied under UV irradiation at various temperatures. The tensile strength of PTT BCF and the K/S value of the sample dyed with disperse dye after UV irradiation decreased with increasing temperature and exposure time. PTT BCF exposed under UV irradiation exhibited lower strength and K/S value compared with the sample after heat treatment. Additional study on the effects of additives used to improve the resistance to fading of disperse dye and degradation of PTT BCF revealed that antioxidant and UV absorbent in PTT BCF showed a small improvement in the strength degradation of PTT BCF and the fading of dye.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.21 no.11
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• pp.180-186
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• 2020

ICT convergence using smart livestock is that in the first-generation dairy smart farm model, each device made by several manufacturers uses its own communication method, limiting the mutual operation of each device. This study uses a model based on open control technology to secure interoperability of existing ICT devices and to manage data efficiently. The open integrated control derived from this process is the software interface structure of Open API. It is an observer that serves as real-time data collection according to the communication method of ICT devices and sensors located at each end. It consists of a broker that connects and transmits to the upper integrated management server. As a result of the performance analysis through verification of two first-generation dairy smart farm model sites, the average daily milk production increased compared to the previous year (farm A 5.13%, farm B 1.33%, p<0.05). Cow days open (DO) was reduced by 17.5% on farm A and 13.3% for farm B(p<0.05). Cows require an adaptation period after the introduction of the ICT device, but if continuous effects are observed, the effect of production can be expected to increase gradually.

• 대한공업교육학회지
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• v.38 no.1
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• pp.275-297
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• 2013

Invention Teacher Education(ITE) is composed of Invention Contents Standards(ICS) and Invention Education Standards(IES). The purpose of this study is to developing ICS of ITE. To achieve the goal, we used the methods of research; analyzing advanced research, content analysis, development, survey, verify the validity. The research results of this study is summarized as follows. ICS is composed of 10 large areas; the concept and characteristic of invention, invention and society, invetion in living, creativity development, invention and design, invention and solving problem, convergence of knowledge and invention, invention project, intellectual properties and patent application, invention and management of technology. 10 large areas has 20 core contents and 90 subordinate elements. ICS will be based on the academic of developing programming besides it will be reference of standards in the case of progressing invention education.