• Title/Summary/Keyword: target and strategies

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A Comparative Study on the Self-help Approach in Rural Development between Vietnam's New Rural Development and Korea's Saemaul Undong

  • Do, Trang Thu;Nguyen, Hanh Thi My;Vu, Trang Thu
    • East Asian Economic Review
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    • v.20 no.1
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    • pp.91-125
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    • 2016
  • Vietnam's "Doi Moi", initiated in 1986, translated to high economic growth and rapid urbanization for the country, but also widened the gap between rural and urban areas. Vietnam's National Target Program on New Rural Development for 2010-2020 was aimed at developing the rural economy and improving the living standards of rural people, but after five years the urban-rural gap remains substantial. Two of the main reasons are the lack of investment capital and lack of effective ways to mobilize community involvement. In contrast, during the 1970s, rural areas in Korea experienced huge improvements under the "Saemaul Undong" movement. The program's success at promoting sustainable development in Korea's rural areas has inspired rural programs in other developing countries. In this paper, we compare and contrast the two movements to provide explanations for the different results between the two countries. Based on this analysis, and policy implications stemming from it, we recommend resource mobilization strategies to change villagers' attitude and increase their involvement in Vietnam's rural development movement, aligning with the inclusivity principle "people know, people discuss, people do and people check".

Marketing Strategies of Fashion Brands -Focused on the British, French, Italian Luxury Fashion Brands- (패션브랜드의 마케팅 전략에 관한 연구 -영국, 프랑스, 이탈리아 력셔리 패션브랜드를 중심으로-)

  • Lee, Hae-Yun;Park, Kwang-Hee
    • The Korean Fashion and Textile Research Journal
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    • v.9 no.2
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    • pp.211-220
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    • 2007
  • The purpose of this study is to analyze characteristics and marketing strategies of the British, French and Italian luxury fashion brands. The subjects of this study are 27 fashion brands which have more than 50 years of tradition and are also members of the Walpole, Comit$\acute{e}$ Colbert, and Altagamma. The common marketing strategies of the luxury fashion brands were; the renewals in the product concept which harmonized traditional elements with modern elements which are designed to meet the needs of new target consumers, the renewals in the promotion such as the large scale of advertising, the frequent publications about the brands, sponsorship of events, the renewals and expansion of distribution channels in global fashion cities, the opening of flagship shop and the renovation of existing shops. Simultaneous renewals in product concepts, in promotion and in distribution will be an effective marketing strategy. Also, a continuous investment in renewal strategies is a key to the success of luxury fashion brand renewals.

Comparison of Effects of Thought Suppression and Thought Substitution Strategies Using Thought Avoidance Training (생각회피훈련을 이용한 생각억제와 생각대체 전략의 효과비교)

  • Shin, Young-Eun;Min, Yoonki;Lee, Young-Chang
    • Science of Emotion and Sensibility
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    • v.24 no.1
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    • pp.3-10
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    • 2021
  • This study examined the effect of intentional thought avoidance(i.e., thought suppression and thought substitution) using "Think and No Think" task. Two syllable words were selected, and recall test was performed with a single subject group. recall accuracy of them was measured in two recall conditions(cue recall and target recall) and four training conditions(thought, thought suppression, thought substitution, and baseline). The results showed that recall accuracy in cue recall condition was better than in target recall condition, regardless of training conditions, and recall accuracy in thought condition was better than in other training conditions, regardless of recall conditions. Also there was significant interaction between recall and training conditions: For thought suppression. there was no difference between two recall conditions, whereas for thought substitution, recall accuracy in cue recall condition was better than in target condition. These findings indicate that thought avoidance strategies, including both thought suppression and thought substitution, are effective in avoiding the specific thought intentionally, and thought suppression and thought substitution could be applied by different mechanism.

A Study on the effect of reference groups influences on public attitude (준거집단이 공중행동에 미치는 효과에 관한 연구)

  • Kim, Seong Hwan
    • Journal of Industrial Convergence
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    • v.2 no.2
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    • pp.47-68
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    • 2004
  • The term "social marketing" was first introduced in 1971 to describe the use of marketing principles and techniques to advance a social cause, idea, or behavior. Social Marketing is a strategy for changing behavior. It utilizes concepts of market segmentation, consumer research, product concept development and testing, directed communication, facilitation, incentives, and exchange theory to maximize the target adopters' response. Social marketing requires knowledge of each target-adopter group, including its 1. social demographic characteristics, 2. psychological profile and 3. behavioral characteristics. To know the target adopters in these three related ways enables social marketer to make more accurate predictions. In addition to differentiating among and selecting target adopter groups, the social marketer will identify influence-holding groups, or influentials, who can affect a program's success. Great changes and opportunities exist to produce changes in the ways that individuals and groups think and behave and in meeting human needs. The balance of the scales of social change, we hope, will shift away from the use of force and violence to the use of persuasion and voluntary action. I trust that this dissertation will be useful highlighting the strategies and means of peaceful, planned social change designed to elevate the quality of life.

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Medical Services Specialization strategies of the Regional Public Hospital through Customer Segmentation (고객세분화를 통한 지방의료원의 의료서비스 전문화 전략)

  • Lee, Jin-Woo
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.16 no.7
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    • pp.4641-4650
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    • 2015
  • This study aims to further strengthen the medical expertise to offer specialized medical care specialization strategies to gain a competitive edge through the customer segmentation of the Regional Public Hospital. Investigation period was selected to study the inpatients 26,658 people January to December 2013. The method of analysis are Cluster analysis and Decision Tree Analysis. In conclusion, female, age over 60, and diseases in musculoskeletal system and connective tissue were commonly selected as identifiers of the target market of Regional Public Hospital. Customers in this target market are loyal to specialized medical service and keeping continuous relationship with these customers through communication and monitoring of results of provided medical service would be important because the effect of word of mouth propagated to other group of customers having equivalent scale of consumption is expected. And the concentration of the scope of medical service of Regional Public Hospital and the collaboration and mutual reliance of medical service under the strategic alliance with other institutions and private hospitals are also needed.

Simulation System Design and Development for Analysis of the Search Strategy for Underwater Targets (수중 표적 탐색전술 분석용 시뮬레이션 시스템 설계 및 개발)

  • Park, Young-Man;Shin, Seoung-Chul
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.13 no.12
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    • pp.2753-2758
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    • 2009
  • The Navy is trying to develop a sonar-operation strategy that efficiently searches for underwater targets. To develop an efficient sonar-operation strategy, a simulation system, which can analyze the efficiency of various operation strategies, is needed. The simulation executes the strategical operation by collecting information of sea environment, destroyer, sonar, and target. Also, it should be able to provide diverse information according to its progression. In this study, the simulation system that can evaluate and analyze the effectiveness of the search strategy for underwater targets in different environments was designed and developed. The simulation system was developed, utilizing the sonar equation and the lateral-range-curve, and it portrays many patterns of realistic movements of a target. This system will contribute to developing and improving efficient sonar-operation strategies to find underwater targets in the future.

A Systematic Literature Review of Manufacturing Companies' Innovation Strategies in Korea (한국의 제조기업 혁신전략에 대한 체계적 문헌 연구)

  • Seungyeon Moon
    • Journal of Technology Innovation
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    • v.31 no.2
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    • pp.135-172
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    • 2023
  • When discussing a company's technology management, manufacturing companies' innovation strategy is vital because it is connected to each company's competitive advantage in various ways, such as technology acquisition, R&D, and product innovation. The research on manufacturing companies' innovation strategies has been studied in various ways, such as performance and resources for innovation; however, very little research has been done to synthesize existing research outcomes. In this study, we conduct a systematic literature review of 51 articles related to manufacturing companies' innovation strategies. By doing so, we synthesized the results of extant studies based on three perspectives: the research target, the research focus, and the types of innovation strategies. In addition, I derived the unique properties of the research on manufacturing companies' innovation strategies. The analysis indicated that Korea's research on manufacturing companies' innovation strategies had been unequally distributed. Based on this, we suggested research agendas for future research on manufacturing companies' innovation strategies.

Identification of the Most Accessible Sites to Ribozymes on the Hepatitis C Virus Internal Ribosome Entry Site

  • Ryu, Kyung-Ju;Lee, Seong-Wook
    • BMB Reports
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    • v.36 no.6
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    • pp.538-544
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    • 2003
  • The hepatitis C virus (HCV) is a major causative agent of chronic hepatitis and hepatocellular carcinoma. The development of alternative antiviral therapies is warranted because current treatments for the HCV infection affect only a limited number of patients and lead to significant toxicities. The HCV genome is exclusively present in the RNA form; therefore, ribozyme strategies to target certain HCV sequences have been proposed as anti-HCV treatments. In this study, we determined which regions of the internal ribosome entry site (IRES) of HCV are accessible to ribozymes by employing an RNA mapping strategy that is based on a trans-splicing ribozyme library. We then discovered that the loop regions of the domain IIIb of HCV IRES appeared to be particularly accessible. Moreover, to verify if the target sites that were predicted to be accessible are truly the most accessible, we assessed the ribozyme activities by comparing not only the trans-splicing activities in vitro but also the trans-cleavage activities in cells of several ribozymes that targeted different sites. The ribozyme that could target the most accessible site identified by mapping studies was then the most active with high fidelity in cells as well as in vitro. These results demonstrate that the RNA mapping strategy represents an effective method to determine the accessible regions of target RNAs and have important implications for the development of various antiviral therapies which are based on RNA such as ribozyme, antisense, or siRNA.

A prognosis discovering lethal-related genes in plants for target identification and inhibitor design (식물 치사관련 유전자를 이용하는 신규 제초제 작용점 탐색 및 조절물질 개발동향)

  • Hwang, I.T.;Lee, D.H.;Choi, J.S.;Kim, T.J.;Kim, B.T.;Park, Y.S.;Cho, K.Y.
    • The Korean Journal of Pesticide Science
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    • v.5 no.3
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    • pp.1-11
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    • 2001
  • New technologies will have a large impact on the discovery of new herbicide site of action. Genomics, combinatorial chemistry, and bioinformatics help take advantage of serendipity through tile sequencing of huge numbers of genes or the synthesis of large numbers of chemical compounds. There are approximately $10^{30}\;to\;10^{50}$ possible molecules in molecular space of which only a fraction have been synthesized. Combining this potential with having access to 50,000 plant genes in the future elevates tile probability of discovering flew herbicidal site of actions. If 0.1, 1.0 or 10% of total genes in a typical plant are valid for herbicide target, a plant with 50,000 genes would provide about 50, 500, and 5,000 targets, respectively. However, only 11 herbicide targets have been identified and commercialized. The successful design of novel herbicides depends on careful consideration of a number of factors including target enzyme selections and validations, inhibitor designs, and the metabolic fates. Biochemical information can be used to identify enzymes which produce lethal phenotypes. The identification of a lethal target site is an important step to this approach. An examination of the characteristics of known targets provides of crucial insight as to the definition of a lethal target. Recently, antisense RNA suppression of an enzyme translation has been used to determine the genes required for toxicity and offers a strategy for identifying lethal target sites. After the identification of a lethal target, detailed knowledge such as the enzyme kinetics and the protein structure may be used to design potent inhibitors. Various types of inhibitors may be designed for a given enzyme. Strategies for the selection of new enzyme targets giving the desired physiological response upon partial inhibition include identification of chemical leads, lethal mutants and the use of antisense technology. Enzyme inhibitors having agrochemical utility can be categorized into six major groups: ground-state analogues, group specific reagents, affinity labels, suicide substrates, reaction intermediate analogues, and extraneous site inhibitors. In this review, examples of each category, and their advantages and disadvantages, will be discussed. The target identification and construction of a potent inhibitor, in itself, may not lead to develop an effective herbicide. The desired in vivo activity, uptake and translocation, and metabolism of the inhibitor should be studied in detail to assess the full potential of the target. Strategies for delivery of the compound to the target enzyme and avoidance of premature detoxification may include a proherbicidal approach, especially when inhibitors are highly charged or when selective detoxification or activation can be exploited. Utilization of differences in detoxification or activation between weeds and crops may lead to enhance selectivity. Without a full appreciation of each of these facets of herbicide design, the chances for success with the target or enzyme-driven approach are reduced.

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Visualizing Live Chromatin Dynamics through CRISPR-Based Imaging Techniques

  • Chaudhary, Narendra;Im, Jae-Kyeong;Nho, Si-Hyeong;Kim, Hajin
    • Molecules and Cells
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    • v.44 no.9
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    • pp.627-636
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    • 2021
  • The three-dimensional organization of chromatin and its time-dependent changes greatly affect virtually every cellular function, especially DNA replication, genome maintenance, transcription regulation, and cell differentiation. Sequencing-based techniques such as ChIP-seq, ATAC-seq, and Hi-C provide abundant information on how genomic elements are coupled with regulatory proteins and functionally organized into hierarchical domains through their interactions. However, visualizing the time-dependent changes of such organization in individual cells remains challenging. Recent developments of CRISPR systems for site-specific fluorescent labeling of genomic loci have provided promising strategies for visualizing chromatin dynamics in live cells. However, there are several limiting factors, including background signals, off-target binding of CRISPR, and rapid photobleaching of the fluorophores, requiring a large number of target-bound CRISPR complexes to reliably distinguish the target-specific foci from the background. Various modifications have been engineered into the CRISPR system to enhance the signal-to-background ratio and signal longevity to detect target foci more reliably and efficiently, and to reduce the required target size. In this review, we comprehensively compare the performances of recently developed CRISPR designs for improved visualization of genomic loci in terms of the reliability of target detection, the ability to detect small repeat loci, and the allowed time of live tracking. Longer observation of genomic loci allows the detailed identification of the dynamic characteristics of chromatin. The diffusion properties of chromatin found in recent studies are reviewed, which provide suggestions for the underlying biological processes.