• 제목/요약/키워드: tailored medicine

검색결과 235건 처리시간 0.026초

사상체질의학을 적용한 국내 간호연구 동향 분석 (Trends in Nursing Research using Sasang Constitutional Theory)

  • 김윤영;권지혜;이시우;유종향
    • 동서간호학연구지
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    • 제18권1호
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    • pp.40-46
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    • 2012
  • Purpose: This research aimed to acquire the trends of Korean nursing research on Sasang constitutional theory. Methods: Total of 25 research articles selected from 17 nursing journals published in Korea since 1990. Data were analyzed by descriptive statistics. Results: Experimental studies preferred to non-experimental research design. The subjects were mostly adult or geriatric population. Most frequently used intervention was diet based on Sasang constitutional theory, and health-related factors were most frequently used as variables. Conclusion: The Sasang constitutional theory considers personal differences important, so it may be suitable for individually tailored nursing care. Therefore, continuous nursing studies using interventions based on Sasang constitutional theory are needed to establish it as one of evidence-based nursing interventions.

Treatment of Complete Persistent Sciatic Artery with Distal Thromboembolism by Thromboembolectomy Only

  • Choi, Yun Kyung;Ahn, Jae Ho;Kim, Kwan Chang;Won, Tae Hee
    • Journal of Chest Surgery
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    • 제45권5호
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    • pp.342-344
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    • 2012
  • A persistent sciatic artery (PSA) is very rare congenital vascular anomaly which is present in 0.025% to 0.04% of the population by an angiographic study. A PSA is usually combined with aneurismal disease or thromboembolic events because of its arteriosclerosis and vessel wall degeneration. The treatments of symptomatic PSA are comprised of exclusion of PSA from circulation and bypass surgery for the lower limb. However, surgical treatment should be tailored to its anatomy and presentation. We report a successful treatment of PSA with distal thromboembolism by thromboembolectomy without bypass surgery.

Recent advances in surveillance colonoscopy for dysplasia in inflammatory bowel disease

  • Soo-Young Na;Won Moon
    • Clinical Endoscopy
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    • 제55권6호
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    • pp.726-735
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    • 2022
  • Inflammatory bowel disease (IBD) has a global presence with rapidly increasing incidence and prevalence. Patients with IBD including those with ulcerative colitis and Crohn's disease have a higher risk of developing colorectal cancer (CRC) compared to the general population. Risk factors for CRC in patients with IBD include long disease duration, extensive colitis, primary sclerosing cholangitis, family history of CRC, stricture, and prior dysplasia. Surveillance colonoscopy for CRC in patients with IBD should be tailored to individualized risk factors and requires careful monitoring every year to every five years. The current surveillance techniques are based on several guidelines. Chromoendoscopy with targeted biopsy is being recommended increasingly, and high-definition colonoscopy is gradually replacing standard-definition colonoscopy. However, it remains unclear whether chromoendoscopy, virtual chromoendoscopy, or white-light endoscopy has better efficiency when a high-definition scope is used. With the development of new endoscopic instruments and techniques, the paradigm of surveillance strategy has gradually changed. In this review, we discuss cutting-edge surveillance colonoscopy in patients with IBD including a review of literature.

Infectious and Non-infectious Complications of Peritoneal Dialysis in Children

  • Cho, Min Hyun
    • Childhood Kidney Diseases
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    • 제24권2호
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    • pp.63-68
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    • 2020
  • Despite the many advantages of peritoneal dialysis (PD) in children with end-stage renal disease, there exist redoubtable complications of PD that should be overcome. To prevent and manage these complications, a multidisciplinary team should provide support highly tailored for each child and family, based on the standardized practice guidelines for the management of pediatric PD. In this review, we summarize the clinical manifestations and management of several complications of PD.

두경부암에서 정밀의료 (Precision Medicine in Head and Neck Cancer)

  • 박혜성;강진형
    • 대한두경부종양학회지
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    • 제39권1호
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    • pp.1-9
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    • 2023
  • Technological advancement in human genome analysis and ICT (information & communication technologies) brought 'precision medicine' into our clinical practice. Precision medicine is a novel medical approach that provides personalized treatments tailored to each individual by precisely segmenting patient populations, based on robust data including a person's genetic information, disease information, lifestyle information, etc. Precision medicine has a potential to be applied to treating a range of tumors, in addition to non-small cell lung cancer, in which precision oncology has been actively practiced. In this article, we are reviewing precision medicine in head and neck cancer (HNC) with focus on tumor agnostic biomarkers and treatments such as NTRK, MSI-H/dMMR, TMB-H and BRAF V600E, all of which were recently approved by U.S. Food and Drug Administration (FDA).

Tailored Dietary Counseling Using Self-Administered Diet History Questionnaire is Effective for Health Promotion : Japanese Experience

  • Satoshi Sasaki;Yoshiko Takahashi;Kim, Mi-Kyung
    • Journal of Community Nutrition
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    • 제5권2호
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    • pp.112-119
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    • 2003
  • Dietary counseling is undoubtedly important for prevention and treatment of chronic diseases. Several dietary counseling methods have been developed and used in Japan to promote healthier diets. However, in Japan, few studies have established effective counseling methods. We developed a computer-assisted tailored dietary counseling system with self-administered diet history questionnaire (DHQ) to assess nutrient intakes and the feedbacks for counseling. We examined the effectiveness of the system in three studies , two among mildly-hypercholesterolemic and one among healthy subjects. We observed significant changes in intakes of targeted nutrients in all three studies. We also observed favorable changes in the corresponding serum and urinary biomarkers in two studies, i.e., non-significant change in serum cholesterol, serum carotene and vitamin C, and a significant change in 24-hour urinary excretion of sodium. In addition, one of the studies observed a significant modified dietary habit for one-year after the intervention was completed. No unfavorable change was observed for non-targeted nutrients in all three studies. The dietary counseling system with DHQ was concluded to be effective among motivated high-risk and healthy subjects. The system's application to other diseases and populations such as children, adolescents, and elderly, should be examined further. (J Community Nutrition 5(2) : 112-119, 2003)

Development of Drugs and Technology for Radiation Theragnosis

  • Jeong, Hwan-Jeong;Lee, Byung Chul;Ahn, Byeong-Cheol;Kang, Keon Wook
    • Nuclear Engineering and Technology
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    • 제48권3호
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    • pp.597-607
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    • 2016
  • Personalized medicine is tailored medical treatment that targets the individual characteristics of each patient. Theragnosis, combining diagnosis and therapy, plays an important role in selecting appropriate patients. Noninvasive in vivo imaging can trace small molecules, antibodies, peptides, nanoparticles, and cells in the body. Recently, imaging methods have been able to reveal molecular events in cells and tissues. Molecular imaging is useful not only for clinical studies but also for developing new drugs and new treatment modalities. Preclinical and early clinical molecular imaging shows biodistribution, pharmacokinetics, mechanisms of action, and efficacy. When therapeutic materials are labeled using radioisotopes, nuclear imaging with positron emission tomography or gamma camera can be used to treat diseases and monitor therapy simultaneously. Such nuclear medicine technology is defined as radiation theragnosis. We review the current development of drugs and technology for radiation theragnosis using peptides, albumin, nanoparticles, and cells.

Surgical Management of Intracranial Aneurysms in the Endovascular Era : Review Article

  • Mason, Alexander M.;Cawley, C. Michael III;Barrow, Daniel L.
    • Journal of Korean Neurosurgical Society
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    • 제45권3호
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    • pp.133-142
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    • 2009
  • The advent of endovascular therapy for intracranial aneurysms and the rapid advances in that field have supplanted microsurgical treatment for many intracranial aneurysms. Applying current outcome data and other parameters, nuances of selecting the modality of treatment for intracranial aneurysms are reviewed. Patient factors, such a age, co-morbidities, vasospasm and other medical conditions, are addressed. A custom-tailored multimodality treatment paradigm for the management of ruptured and unruptured aneurysms will maximize the favorable results seen in this difficult patient population.

Staged Repair after Hybrid Palliation for Interrupted Aortic Arch with Systemic Outflow Tract Obstruction

  • Lee, June;Kim, Yong Han;Lee, Cheul
    • Journal of Chest Surgery
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    • 제52권1호
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    • pp.32-35
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    • 2019
  • Surgical management of interrupted aortic arch (IAA) with systemic outflow tract obstruction is clearly a challenge. If both ventricles are adequate, the Yasui operation is a useful option. Otherwise, a staged approach through initial hybrid palliation and delayed biventricular repair, tailored to the degree of obstructed outflow, serves to avoid a high-risk neonatal procedure. Herein, we present a patient with IAA and severe systemic outflow tract obstruction whose treatment involved hybrid palliation, followed by a Yasui operation.

Home mechanical ventilation in children with chronic respiratory failure: a narrative review

  • Soyoung Kwak
    • Journal of Yeungnam Medical Science
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    • 제40권2호
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    • pp.123-135
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    • 2023
  • Advances in perinatal and pediatric intensive care and recent advances in mechanical ventilation during the last two decades have resulted in an exponential increase in the number of children undergoing home mechanical ventilation (HMV) treatment. Although its efficacy in chronic respiratory failure is well established, HMV in children is more complex than that in adults, and there are more considerations. This review outlines clinical considerations for HMV in children. The goal of HMV in children is not only to correct alveolar hypoventilation but also to maximize development as much as possible. The modes of ventilation and ventilator settings, including ventilation masks, tubing, circuits, humidification, and ventilator parameters, should be tailored to the patient's individual characteristics. To ensure effective HMV, education for the parent and caregiver is important. HMV continues to change the scope of treatment for chronic respiratory failure in children in that it decreases respiratory morbidity and prolongs life spans. Further studies on this topic with larger scale and systemic approach are required to ensure the better outcomes in this population.