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Anti-obesity effects of Chrysanthemum indicum L. in C57BL/6 mice induced by high fat diet (고지방식이로 유도된 C57BL/6 mice에서 감국이 미치는 비만억제 효과)

  • Choi, Jae Young;Lee, Ja-bok;Kim, Myeong-ok
    • Journal of Convergence for Information Technology
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    • v.11 no.4
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    • pp.111-121
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    • 2021
  • In order to determine the possibility that Chrysanthemum indicum L. cultured with Lactococcus lactis (CILL) is a material for obesity suppression food, the body weight, body fat mass, and T cells were determined in C57BL/6 mice induced by a high fat diet. The CILL (25.15±2.44 g) demonstrated weight loss from week 4 onward and maintained a low weight gain from week 1 to week 8 (1.00±0.53 g). The 8-week body weight (30.38±4.17 g) indicated loss of 13.15% when compared to the HFD (60% high fat diet, 34.99±2.09 g). Fat mass decreased to 10.3022±2.8813 g, and the absolute liver weight decreased relative to that in the HFD. CD4+ T cells were 4.84±1.33%, CD8+ T cells 7.02±2.26%, and CD4+CD8+ T cells 1.46±0.81%, which were all higher than those in the HFD. As a result, CILL can be used as a material for preventing obesity as an effective measure toward reducing weight when consumed orally.

Effects of Low-Dose Fractionated Total Body Irradiation on Murine Immune System (마우스에서 전신 저선량 분할 방사선 조사에 의한 면역학적 변화 평가)

  • Kim, Mi-Hyoung;Rhu, Sang-Young;Lim, Dae-Seog;Song, Jie-Young
    • Journal of Radiation Protection and Research
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    • v.39 no.3
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    • pp.134-141
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    • 2014
  • Along with the wide use of radiotherapy in cancer treatment, there is growing interest in beneficial effect of low-dose irradiation (LDI) in cancer therapy. Therefore, we investigate how LDI affects immune responses in mice model. Total body irradiation (TBI) on C57BL/6 mice was given at low-dose rate of $1mGy{\cdot}min^{-1}$ using $^{137}Cs$ source at three times for consecutive three days. Hematological examination, total cell numbers of spleen, populations and characteristics of splenocytes were determined. Total numbers of RBC or platelet in irradiated mice showed no significant changes. WBC counts were decreased in a dose-dependent manner 2 days after TBI, however, these differences are gradually waned until 28 days. Dose-dependent decrease in the number of splenocytes of TBI mice at day 2 was also improved as time progressed. While the level of Foxp3 mRNA was decreased, the frequency of $CD4^+$ T cells and $CD69^+$ cells in spleen was increased at day 2 and 14. Fractionated low-dose TBI on mice exhibited normal body weight with no distinguishable behavior during whole experimental periods. These results suggest that some parameters of immune system could be altered and evaluated by fractionated low-dose TBI and be used to broaden boundary of low dose radiation research.

Audio Stream Delivery Using AMR(Adaptive Multi-Rate) Coder with Forward Error Correction in the Internet (인터넷 환경에서 FEC 기능이 추가된 AMR음성 부호화기를 이용한 오디오 스트림 전송)

  • 김은중;이인성
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.26 no.12A
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    • pp.2027-2035
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    • 2001
  • In this paper, we present an audio stream delivery using the AMR (Adaptive Multi-Rate) coder that was adopted by ETSI and 3GPP as a standard vocoder for next generation IMT-2000 service in which includes combined sender (FEC) and receiver reconstruction technique in the Internet. By use of the media-specific FEC scheme, the possibility to recover lost packets can be much increased due to the addition of repair data to a main data stream, by which the contents of lost packets can be recovered. The AMR codec is based on the code-excited linear predictive (CELP) coding model. So we use a frame erasure concealment for CELP-based coders. The proposed scheme is evaluated with ITU-T G.729 (CS-ACELP) coder and AMR - 12.2 kbit/s through the SNR (Signal to Noise Ratio) and the MOS (Mean Opinion Score) test. The proposed scheme provides 1.1 higher in Mean Opinion Score value and 5.61 dB higher than AMR - 12.2 kbit/s in terms of SNR in 10% packet loss, and maintains the communicab1e quality speech at frame erasure rates lop to 20%.

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Effects of Bedding Material Composition in Deep Litter Systems on Bedding Characteristics and Growth Performance of Limousin Calves

  • Meng, J.;Shi, F.H.;Meng, Qingxiang;Ren, L.P.;Zhou, Z.M.;Wu, H.;Zhao, L.P.
    • Asian-Australasian Journal of Animal Sciences
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    • v.28 no.1
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    • pp.143-150
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    • 2015
  • The objective of this study was to evaluate the effects of different litter mixture compositions on bedding system temperature, pH and volatile fatty acid and ammonia-N ($NH_3$-N) content, and the serum physico-chemical parameters and growth indices of calves. Thirty-two Limousin calves ($280{\pm}20kg$) were randomly assigned to four groups (n = 8 for each group) according to the bedding system used: i) control with soil only (CTR); ii) mixture with 50% paddy hulls (PH), 30% saw dusts (SD), 10% peat moss (PM) and 10% corn cobs (CC) (TRT1); iii) mixture with 15% PH, 15% SD, 10% PM, 40% CC, and 20% corn stover (CS) (TRT2); iv) mixture with 30% PH, 10% PM, 40% CC, and 20% CS (TRT3). The litter material combinations of different treatments were based on the cost of bedding system materials in China. The cost of four treatments from low to high: Control$NH_3$-N level (271.83 to 894.72 mg/kg) was lowest for TRT1 (p<0.0001) and highest for TRT2 (p<0.0001). The acetate, propionate and butyrate levels were highest for the control group (p<0.0001). In all the groups, the pH value (6.90 to 9.09) increased at the beginning and later remained stable at below 9.09. The temperature of deep litter increased at the first week and reached the maximum ($42.1^{\circ}C$) on day 38. 3,5,3'-Triiodothyronine ($T_3$) levels in the TRT1 group animals (p<0.0001) were lower than those in the control and TRT2 animals. 3,5,3',5'-Tetraiodothyronine ($T_4$) in the TRT1 group (p = 0.006) was lower than that in the other treatment groups. Cortisol (COR) in the control and TRT1 group was lower (p<0.0001) than that in the TRT2 and TRT3 groups. Corticosterone (CORt) in the control group was higher (p<0.0001) than that in the treatment groups. The findings indicate that the deep litter bedding systems provided better conditions for animal health and growth performance compared with the control system. Furthermore, the litter composition of TRT1 was found to be optimal among the three treatment groups.

Hemato-Biochemical Indices of Hanwoo Cattle Raised at Different Altitudes (서로 다른 고도에서 사육된 비육한우의 혈액-혈청 지수)

  • Ji, Joong-Ryong;Alam, Md. Rafiqul;Na, Chong-Sam;Kim, Nam-Soo
    • Journal of Veterinary Clinics
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    • v.28 no.2
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    • pp.219-224
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    • 2011
  • The health status of three groups of Hanwoo steers (n=157) aged 2-3 years, raised at three different altitudes (600 m, n=50; 200-400 m, n=58; plane land, n=49) and environment with more or less similar management have been evaluated through hematological, biochemical and globulin examinations in order to determine the optimum environment suitable for raising cattle while at the same time minimizing the risk of disease. Five mL of blood samples from each animal were collected by jugular veinipuncture and 2 mL was transferred to a tube containing EDTA for complete blood count (CBC) and 3 mL in lithium heparin for chemistry screening (CS) and immunoassay. Among the CBC parameters a significantly higher white blood cell count (tWBC), total red blood cell count (tRBC), hemoglobin (Hb) and packed cell volume (PCV) were noticed in the high altitude groups, whereas those were lower in the plane land group. In the CS parameters higher levels of aspartate aminotransferase (AST), creatinine, lactate dehydrogenase (LDH) and total bilirubin (TBL) were found in the plane land group, whereas those were lower in the high altitude groups. The total protein (significantly) and globulins were higher in the 600 m group. The results of this study revealed that the overall health status of the Hanwoo cattle based on the hemato-biochemical indices was superior in the highest altitude and inferior in the plane land group but all the parameters were within the reference range in all the groups. Therefore, for recommendation of a suitable environment at an appropriate altitude for raising cattle there need to be further studied along with the hemato-biochemical parameters; considering, breeding, feeding, management, marketing, waste disposal and other factors.

The Effects of Attitude to Death in the Hospice and Palliative Professionals on Their Terminal Care Stress (호스피스 완화의료 전문인력의 죽음에 대한 태도가 임종돌봄 스트레스에 미치는 영향)

  • Yang, Kyung Hee;Kwon, Seong Il
    • Journal of Hospice and Palliative Care
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    • v.18 no.4
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    • pp.285-293
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    • 2015
  • Purpose: This study was conducted to explore the effects of attitude to death in hospice and palliative professionals on their terminal care stress, and to analyze relationships among variables related to the two aforementioned parameters, such as depression and coping strategies. Methods: Participants were 131 hospice and palliative professionals from the cancer units of two tertiary hospitals and two general hospitals, two hospice facilities, two geriatric hospitals, and two convalescent hospitals in J province. Data were collected from April through June 2015 and analyzed using t-test, factor analysis, ANOVA ($Scheff{\acute{e}}$ test), ANCOVA, and Pearson's correlation and a path analysis using the SPSS/WIN 21.0 and AMOS 18.0 programs. Results: The score for attitude to death was low (2.63), and that for depression was 0.45. Among all, 16.0% of the participants showed need for depression management. They scored 3.82 on terminal care stress. The subcategory with the highest mark was inner conflicts on limitation given availability of medical services (4.04). The score on coping strategy was low (3.13). They used passive coping strategies such as interpersonal avoidance (4.03), fulfilling basic needs (3.65) such as sleeping or eating. Attitudes to death had a direct negative effect on the terminal care stress level and indirectly affected through depression and fulfilling basic needs (CS2). Conclusion: It is necessary to provide hospice and palliative professionals with education on death and dying, as well as access to programs that provide emotional support and promote positive cognition of death and dying.

Validity of Arch Relationship Measurements in Digital Dental Models (디지털 치열 모형에서 악궁 관계 지표 측정의 타당성)

  • Ryu, Jiin;Yang, ByoungEun;Lee, Hyelim
    • Journal of the korean academy of Pediatric Dentistry
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    • v.49 no.1
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    • pp.14-24
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    • 2022
  • The aim of the present study is to evaluate the validity of orthodontic measurements including tooth width, Bolton ratio, overjet and overbite on the digital dental models. Dental models of the subjects aged 12 to 18 were obtained in 3 different forms, which were conventional stone model, digital model created with Freedom HD model scanner, and digital model produced with CS3600 intraoral scanner. After measurements were made on the models, reliability and reproducibility of the measurements were evaluated by using intraclass correlation coefficient, while validity was assessed with paired t-test. As a result, significant reliability and reproducibility were verified, with intraclass correlation coefficient exceeding 0.750 in all groups. Measurements of the model scanned group showed an adequate validity in overall and anterior Bolton ratio, overjet, and overbite. Intraoral scanned models showed an adequate validity in anterior Bolton ratio, and overjet. Measurement on intraoral scanned digital models can be considered as an alternative for young children who have difficulty in taking impression. Furthermore, careful considerations on measurement error should be made in clinical situations.

A Design of Secure Communication for Device Management Based on IoT (사물인터넷 기반 디바이스 관리를 위한 안전한 통신 프로토콜 설계)

  • Park, Jung-Oh;Choi, Do-Hyeon;Hong, Chan-Ki
    • Journal of Convergence for Information Technology
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    • v.10 no.11
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    • pp.55-63
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    • 2020
  • The IoT technology is a field that applies and converges the technologies in the existing industrial environment, instead of new technologies. The IoT technology is releasing various application services converged with other industries such as smart home, healthcare, construction, and automobile, and it is also possible to secure the work efficiency and convenience of users of IoT-based technologies. However, the security threats occurring in the IoT-based technology environment are succeeding to the vulnerability of the existing wireless network environment. And the occurrence of new and variant attacks in the combination with the ICT convergence environment, is causing damages. Thus, in the IoT technology-based environment, it would be necessary to have researches on the safe transmission of messages in the communication environment between user and device, and device and device. This thesis aims to design a safe communication protocol in the IoT-based technology environment. Regarding the suggested communication protocol, this thesis performed the safety analysis on the attack techniques occurring in the IoT technology-based environment. And through the performance evaluation of the existing PKI-based certificate issuance system and the suggested communication protocol, this thesis verified the high efficiency(about 23%) of communication procedure. Also, this thesis verified the reduced figure(about 65%) of the issued quantity of certificate compared to the existing issuance system and the certificate management technique.

The Study on the Effect of the Middle-aged Women's Upper lips musculo-cutaneous by SUKI® program (SUKI 중재에 의한 중년 여성의 윗입술근피에 미치는 연구)

  • Lee, Su-Bum;Hong, Seong-Gyun
    • Journal of Convergence for Information Technology
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    • v.11 no.2
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    • pp.194-200
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    • 2021
  • The aim of this study was proceed for 6weeks to determine the effect of middle-aged women's upper lips ms by SUKI programs. A total of 20 subjects were tested, and the SUKI arbitration programs of Pattern T1, Pattern T2, Pattern T3, Pattern T4 were adopted three times a week in six weeks. The results were as this. It showed a significant difference in the EG, although some of the intra-group comparisons of the upper lip ms. Therefore, SUKI programs have been shown to help improve the elasticity of the upper lip ms(p<.05). In this study, the SUKI program was used based on the fact that although limited, the elasticity of the upper lip ms, located in the facial part of a middle-aged woman, causes various wrinkles around her mouth, making them lose confidence in their appearance. This also suggests that normal facial ms can affect the appearance of the female middle-aged woman, and it was intended to suggest some ways to manage the appearance by proper management of facial muscle according to the life cycle of the female middle-aged woman. In conclusion, we hope that in the future, various experiments will be used as new research data on how to prevent women's facial skin beauty and wrinkles and help improve elasticity of facial muscles around the mouth.

Proposal of a mobility management scheme for sensor nodes in IoT(Internet of Things) (사물인터넷(IoT)환경에서 센서 노드들의 이동성 관리 방안에 관한 제안)

  • Park, Seung-Kyun
    • Journal of Convergence Society for SMB
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    • v.6 no.4
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    • pp.59-64
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    • 2016
  • 6LoWPAN (IPv6 over Low Power Wireless Sensor Network) standardized by IETF does not support the mobility of wireless sensor nodes. Since the wireless sensor node, subject to a lot of constraints in the CPU, memory, a battery is not easy to apply to existing protocols such as Mobile IPv6. In this paper, we propose a novel mobility management architecture and methods to work with 6LoWPAN based on the analysis on FPMIPv6 (Fast PMIPv6) the host is not a handover procedure performed in order to support the mobility of such sensor nodes. It was suggested the use of a dispatch code pattern that is not currently used in 6LoWPAN for inter-working, MAG and MAC, MAC in order to reduce packet loss caused as the authentication delay in the handover process to minimize the power consumption of a sensor node that is caused by the re-transmission the new concept of temporary guarantee (temporary guarantee) and trust relationships (trust relationship) between AAA and introduced.