• Title/Summary/Keyword: tCS

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Optimum design of multi-span composite box girder bridges using Cuckoo Search algorithm

  • Kaveh, A.;Bakhshpoori, T.;Barkhori, M.
    • Steel and Composite Structures
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    • v.17 no.5
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    • pp.705-719
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    • 2014
  • Composite steel-concrete box girders are frequently used in bridge construction for their economic and structural advantages. An integrated metaheuristic based optimization procedure is proposed for discrete size optimization of straight multi-span steel box girders with the objective of minimizing the self-weight of girder. The metaheuristic algorithm of choice is the Cuckoo Search (CS) algorithm. The optimum design of a box girder is characterized by geometry, serviceability and ultimate limit states specified by the American Association of State Highway and Transportation Officials (AASHTO). Size optimization of a practical design example investigates the efficiency of this optimization approach and leads to around 15% of saving in material.

Tacrolimus and cyclosporine A inhibit both class I-restricted presentation pathway and class II- restricted presentation pathway of exogenous antigen.

  • Yang, In-Ho;Lee, Young-Ran;Kim, Hyeon-Seon;Lee, Jae-Kwon;Im, Sun-A;Li, Hong;Han , Kun;Song, Suk-Gil;Lee, Chong-Kil
    • Proceedings of the PSK Conference
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    • 2002.10a
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    • pp.306.2-306.2
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    • 2002
  • The main targets for the immunosuppressive calcineurin inhibitors. tacrolimus (FK-506) and cyclosporine A (CsA). have been considered to be activated T cells. but not antigen presenting cells (APCs). In the present study. we examined the effects of these drugs on the MHC-restricted presentation of exogenously added antigen. ovalbumin (OVA). in dendritic cells (DCs). Particulate form of OVA was efficiently captured. processed and presented on class I MHC molecules (cross-presentation) as well as on class II MHC molecules. (omitted)

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TERMINAL SPACES OF MONOIDS

  • Amartya Goswami
    • Communications of the Korean Mathematical Society
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    • v.39 no.1
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    • pp.259-266
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    • 2024
  • The purpose of this note is a wide generalization of the topological results of various classes of ideals of rings, semirings, and modules, endowed with Zariski topologies, to r-strongly irreducible r-ideals (endowed with Zariski topologies) of monoids, called terminal spaces. We show that terminal spaces are T0, quasi-compact, and every nonempty irreducible closed subset has a unique generic point. We characterize rarithmetic monoids in terms of terminal spaces. Finally, we provide necessary and sufficient conditions for the subspaces of r-maximal r-ideals and r-prime r-ideals to be dense in the corresponding terminal spaces.

Feeding Unprotected CLA Methyl Esters Compared to Sunflower Seeds Increased Milk CLA Level but Inhibited Milk Fat Synthesis in Cows

  • Dohme-Meier, F.;Bee, G.
    • Asian-Australasian Journal of Animal Sciences
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    • v.25 no.1
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    • pp.75-85
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    • 2012
  • An experiment was conducted to compare the effect of the same amount of 18:2 offered either as 18:2n-6 or as a mixture of unprotected 18:2c9t11 and 18:2t10c12 on feed intake, milk components as well as plasma and milk fatty acid profile. Fifteen cows were blocked by milk yield and milk fat percentage and within block assigned randomly to 1 of 3 treatments (n = 5). Each cow passed a 12-d adjustment period (AP) on a basal diet. After the AP cows received 1 of 3 supplements during an 18-d experimental period (EP). The supplements contained either 1.0 kg ground sunflower seeds (S), 0.5 kg conjugated linoleic acid (CLA)-oil (C) or 0.75 kg of a mixture of ground sunflower seeds and CLA-oil (2:1; SC). All 3 supplements contained the same amount of 18:2 either as CLA (${\Sigma}18$:2c9t11+18:2t10c12, 1:1) or as 18:2c9c12. During the last 2 d of AP and the last 4 d of EP feed intake and milk yield were recorded daily and milk samples were collected at each milking. Blood samples were collected from the jugular vein on d 11 of AP and d 15 and 18 of EP. The 18:2 intake increased in all treatments from AP to EP. Regardless of the amount of supplemented CLA, the milk fat percentage decreased by 2.35 and 2.10%-units in treatment C and SC, respectively, whereas in the treatment S the decrease was with 0.99%-unit less pronounced. Thus, C and SC cows excreted daily a lower amount of milk fat than S cows. The concentration of trans 18:1 in the plasma and the milk increased from AP to EP and increased with increasing dietary CLA supply. While the concentration of 18:2c9t11 and 18:2t10c12 in the plasma and that of 18:2t10c12 in the milk paralleled dietary supply, the level of 18:2c9t11 in the milk was similar in C and CS but still lower in S. Although the dietary concentration of CLA was highest in treatment C, the partial replacement of CLA by sunflower seeds had a similar inhibitory effect on milk fat synthesis. Comparable 18:2c9t11 levels in the milk in both CLA treatments implies that this isomer is subjected to greater biohydrogenation with increasing supply than 18:2t10c12. The fact that unprotected 18:2t10c12 escaped biohydrogenation in sufficient amounts to affect milk fat synthesis reveals opportunities to develop feeding strategies where reduced milk fat production is desirable or required by the metabolic state of the cow.

A Blockchain-based IIoT Information Collection Model for Improving the Productivity of Small and Medium Businesses (중소기업 생산성 향상을 위한 블록체인 기반의 IIoT 정보 수집 모델)

  • Jeong, Yoon-Su;Kim, Yong-Tae;Park, Gil-Cheol
    • Journal of Convergence for Information Technology
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    • v.9 no.12
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    • pp.1-7
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    • 2019
  • As the cloud environment has become more prevalent among large companies, small and medium-sized companies are also trying to utilize various technologies (IoT, blockchain, etc.) that use cloud services as a way to coexist with large companies. In this paper, a blockchain-based IoT information collection model is proposed to efficiently handle large volumes of IoT data produced by small businesses in order to improve information efficiency of SMEs. The proposed model allowe d small businesses to improve their production efficiency by independently creating groups of the same information so that data that could be generated at the endpoints of small businesses can be block-chained and forwarded to the data center for analysis. In addition, the proposed model's performance assessment was assumed to handle the production throughput of data processed in IoT for small and medium businesses, not large enterprises, so the link between large volumes of data processed in the proposed model could be maintained evenly. One of the biggest features of the proposed model is the ability to expand processes to efficiently control the information of prod ucts produced, as well as the productivity of small and medium enterprises.

The Effects for Brain stress by SUKI Alternative Therapy (SUKI 대체의학에 의한 뇌스트레스 감소 효과 연구)

  • Park, Young-Sik;Hong, Seong-Gyun
    • Journal of Convergence for Information Technology
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    • v.9 no.3
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    • pp.104-111
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    • 2019
  • The purpose of this study is to know the change of brain wave with stress by SUKI pressure alternative therapy. The experiment group was 12 students(male 6/female 6) with complained upper trapezius pain. Calculated the brain wave before and after stimulate the upper trapezius trigger point by SUKI and the stimulate time was 3min each persons(FP2, F3, F4, FP1, T3, T4, P3, P4). the experimet periods was 5times in a weeks with EEG(QEEG-S). The Date collecting used by Telescan(LXE5209). All the data was analyzed with SPSS 22.0 for window program. To compare the differences before and after the point pressure method, a corresponding sample of t-test was performed, and the statistical significance level was p<.05. The results was followed. The points of Fp2, F3, F4(*p<0.049, *p<0.042, *p<0.019) of EEG was showed a significant differences but Fp1, T3, T4, P3, P4 points did not showed. The SUKI alternative medicine techniques had a reduced effects for the some kind of brain stress. It is need to continuous research in the future.

Extended Service Filtering Technique for Overload Control of Televoting Service Required for the Specialized Resources of Intelligent Peripheral (지능형 정보제공 시스템의 특수 지원을 이용하여 제공되는 전화투표 서비스의 과부하 제어를 위한 확장된 서비스 필터링 기법)

  • Jeong, Gwang-Je
    • The Transactions of the Korea Information Processing Society
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    • v.3 no.7
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    • pp.1727-1738
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    • 1996
  • This paper proposes a extended service filtering technique to solve overload control problems inService Con-trol Poin(SCP) due to Televoting (VOT) services with heavy traffic characteristics. Also, this paper compares this new technique with existing IN overload control lechniques, and calculate steady state call blocking probabilities in In under overload conditions. The proposed technique considers SCP overload and IN CS-1services such as VOT service that need to use the specialized resources of IP. This technique uses first an activating step which SCP sends service filtering request to SSP and IP for the start of service filtering. Then, in the filtering step SSP sendas filtering results to SCP periodically or each N-calls.Also,when filtering time-out timer expired or call counter value exceeded maximum number of calls,SSP stops service filtering,and sends ser-vice filteing response to SCP in the deactivating step. The application of this techique to VOT service defined in IN CS-1 service is investigated and analyzed by using an analytical VOT service model.In order to apply this technique to VOT service, this paper also discusses VOT service and the corresponding N architecture including Service Switching Point(SSP),SCP and IP. Then this paper also constructs an analytical VOT service model,and calculates SCP and SSP/IP(circuit)call blocking probablities.With the application of this new technique,this paper shows good performance enhancements in SCP call blocking probability.

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Multidimensional Factors Influencing Burnout in Intensive Care Unit Nurses (다차원적 요인이 중환자실 간호사의 소진에 미치는 영향)

  • Kim, Se Ra;Jeon, Mi-Kyeong;Hwang, Jin Hee;Choi, Ae Ran;Kim, In Sook;Pyon, Mi Kyoung;Moon, Kyoung Eun;Kim, Mun Hee;Shin, Na Ra;Lee, Soon Haeng
    • Journal of Korean Clinical Nursing Research
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    • v.23 no.1
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    • pp.9-19
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    • 2017
  • Purpose: This study aimed to identify multidimensional factors influencing burnout in intensive care unit(ICU) nurses. Methods: A descriptive cross-sectional design was used. Data were collected during February 2016 from a convenience sample of 222 tertiary hospital ICU nurses and analyzed using t-test, ANOVA, correlation analysis, and multiple regression analysis. Results: Burnout correlated positively with compassion fatigue (CF)(r=.37, p<.001), and negatively with compassion satisfaction (CS)(r=-.66, p<.001). The regression model explained 57% of the variance in burnout. For individual characteristics in the model, perceived health status (${\beta}=-.27$, p<.001) and gender (${\beta}=.14$, p=.028) were the most influential factors for ICU nurses' burnout. In the model with added work-related characteristics, nursing environment (${\beta}=-.22$, p=.001), perceived health status (${\beta}= -.20$, p=.001), and satisfaction with department (${\beta}=-.19$, p=.007) were the most influential factors. Finally, for the model with psychological characteristics added, CS (${\beta}=-.56$, p<.001) and CF (${\beta}=.35$, p<.001) were the most influential factors. Conclusion: Results reveal that most ICU nurses have a moderate level of CF and a moderate to high level of CS and burnout, and that individual, work-related and psychological factors are relevant in ICU nurses' burnout. Programs or interventions to reduce burnout should be developed taking into account these multidimensional factors.

Comparative Study on the Regimens with Pyrazinamide or Ofloxacin in the retreatment of pulmonary tuberculosis (폐결핵 재치료에서 Pyrazinamide 복합처방과 Ofloxacin 복합처방의 효과에 관한 비교 연구)

  • Choi, In Hwan;Park, Seung Kyu;Kim, Kyeong Ho;Kim, Jin Ho;Kim, Cheon Tae;Song, Sun Dae
    • Tuberculosis and Respiratory Diseases
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    • v.43 no.6
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    • pp.871-881
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    • 1996
  • Objective: In the early short-term therapy of pulmonary tuberculosis, PZA is used for the first two months on 6EHRZ therapy but PZA is not effective in the case of long-tenn use PZA for retreatment in the sensitive relapse or acquired drug resistance for PZA. But in the endemic area as Korea, if we can't use PZA in the retreatment of pulmonary tuberculosis, we can't expect the success for retreatment of pulmonary tuberculosis, therefore we need new drugs substituting for PZA. In these days, 4 - fluoroquinolone derivatives were investigated and only ofloxacin and ciprofloxacin of derivatives were known to be effective but the effectiveness was also not certain because the result was experimental or combined with other bacteriocidal drugs and datas on effectiveness of pulmonary tuberculosis were so little. Therefore these drugs should be use with other two or three strong-acting drugs in the last period of retreatment of pulmonary tuberculosis. The ofloxacin or ciprofloxacin is used in some area in Korea but randomly and needed more study. We did this study for proving the effectiveness of these drugs and establishment of retreatment regimen for pulmonary tuberculosis. Methods: Retrospective cohort study of 83 drug-resistant pulmonary tuberculosis patients at National Masan Tuberculosis Hospital from Jan. 1994 to dec. 1995 was made. All the patients taken medicine for 2nd ami-tuberculosis regimens for the first lime. We separated the patients by two groups.(Group I : OFX+ PTA + CS+PAS + Injection, Group II: PZA + PTA+ CS + PAS + Injection). We compared the difference between two groups and tested the confidence limit about results after treatment by $\chi$2-test and T-test. Results : 1. The age distribution was most frequent in fourth decade(29.2% in Group I, 37.1% in Group II) and the mean age was 43.9 year in Group I, and 39.0 year in Group II, but had no significant difference between two groups. The sex distribution was more frequent in the males(68.8% in Group I, 85.7% in Group II), but had no significant difference. 2. Family history was 29.2% in Group I, 28.6% in Group II, but had no significant difference. 3. In the respect of extent of disease, far-advanced stare was 60.4% in Group I, 74.3% in Group II, but had no significant difference. 4. The side effects for drugs showed in 58.3% in Group I and 65.7% in Group II, and the gastrointestinal trouble showed 25.0% in Group and arthralgia 34.3% in Group II predominantly respectively and had the significant difference(p<0.05). 5. The negative conversion rate on sputum AFB smear was 87.5% in Group I and 80.0% in Group II, but had no significant difference. But the negative conversion rate on sputum AFB culture was 83.3% in Group I and 57.1 % in Group II and had the significant difference(p<0.05). 6. The success rate of treatment was 87.5 % in Group I and 83.3 % in Group II but had no significant difference. Conclusion : In the retreatment of pulmonary tuberculosis, ofloxacin is useful drug for the patients who are not available to use PZA and can be use effectively substituting for PZA.

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Effects of Jinyeosoo Clean Mist on the Improvement of Facial Skin in Middle-aged Women (진여클린미스트를 이용한 중년여성의 안면피부개선 효과)

  • Kim, Min Joo
    • Journal of Convergence for Information Technology
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    • v.11 no.3
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    • pp.220-228
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    • 2021
  • In this study, 20 middle-aged women aged from 35 to 55 were studied from October 12, 2020 to November 15, 2020 to find out the effects of improvement of facial skin of Jinyeosoo Clean Mist. Among the 20 participants, 10 were divided into experimental group and 10 control group. The Janus facial skin scope system (PSI Co.) used on the skin to measure pore, wrinkles, elasticity, UV pigmentation, and skin tone observed depending the difference in light sources. The facial examination took place 10 minutes after cleansing to stabilize and a total of 4 examinations were carried out after every week of using Jinyeosoo Clean Mist for 4 weeks. For statistical processing, SPSS statistics program 21.0 was utilized to compare the mean averages of pre-experimental and post-experimental data from the above two groups - the experimental group that used Jinyeosoo Clean Mist (hydrogen ion mist) 1 and 2 and the control group that did not use the subject products - and the corresponding sample t-test was used. As a result of the analysis, the group that used Jinyeosoo Clean Mist showed difference in pores (t=3.280, p<.05), wrinkles (t=4.353, p<.01) and elasticity (t=3.003, p<.05), skin tone(t=3.280, p<.01) under the statistical significance level.