• Title/Summary/Keyword: systemic administration

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Factors Influencing the Use Diffusion of Cosmetic Medical Information Mobile Platform: Based on Technology Acceptance Model (미용성형의료정보 모바일 플랫폼의 사용확산에 영향을 미치는 요인: 기술수용모델을 기반으로)

  • Youyoung Park;Jeman Boo
    • Korea Trade Review
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    • v.45 no.1
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    • pp.279-300
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    • 2020
  • The cosmetic medical information mobile platform is evolving into a new channel for searching and obtaining relevant information before using cosmetic medical service. In addition, the medical institutions can facilitate the medical contracts, and take advantage of systemic customer management through the cosmetic medical information mobile platform. Therefore, the paradigm of the cosmetic medical mobile service industry is facing a flow of change through the use diffusion of cosmetic medical information mobile platform. In this study, in order to explore the factors affecting the use diffusion of the cosmetic medical information mobile platform, this study used the research model of the influence of the characteristics of the cosmetic medical information mobile platform on perceived convenience and usefulness, and use diffusion by applying TAM(Technology Acceptance Model). As a result, immediateness, interactivity, and customization in the characteristics of cosmetic medical information mobile platform had positive effects on the perceived convenience. Also, interactivity, customization, and economics had positive impacts on perceived usefulness. In addition, perceived convenience and usefulness had positive effects on the use diffusion. Through this study, the factors influencing the use diffusion of cosmetic medical information mobile platform were actually explored, and the service value of the cosmetic medical information mobile platform were categorized. Future research is expected to contribute to the continuous improvement of quality and expansion of the cosmetic medical service market based on various research.

FLUORIDE CONCENTRATION IN URINE EXCRETED AFTER FLUORIDE ADMINISTRATION (불소투여 후 배출된 요내 불소농도 변화에 관한 연구)

  • Lee, Bo-Kyung;Kim, Tae-Young;Kim, Chong-Chul
    • Journal of the korean academy of Pediatric Dentistry
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    • v.27 no.1
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    • pp.62-69
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    • 2000
  • Part of the locally applied, as well as the systemic applied, fluoride is absorbed into the body to aid in the prevention of caries. However, beyond a certain level, systemic distribution of fluoride can cause chronic fluorosis with attending systemic symptoms and dental fluorosis. Thus it is vital to determine the level of fluoride with minimal side effects which will provide optimal caries prevention. A commonly utilized method of regressively determining fluoride intade is to measure the fluoride concentration of excreted urine. Thus, the aim of this study was to determine the clearance time and concentration of fluoride in urine after administration of various doses of fluoride using HMDS-diffusion technique and fluoride ion electrode(Orion, 96-09, U.S.A.). Urine samples were collected in 7 adult subjects every morning after administration of fluoride supplements such as no fluoride(control group), 1mg fluoride(group 1), 2mg fluoride(group 2), 3mg fluoride(group 3), 4mg fluoride(group 4). The obtained results were as follows 1. Mean urinary fluoride concentration of control group was $0.707{\pm}0.362ppm$. 2. Fluoride levels followed as group 4(4.076ppm). group 3(2.400ppm), group 2(1.494ppm), group 1(1.051ppm) at day 1 after fluoride administration. There were no statistical differences between the urinary fluoride concentration of group 1, 2, 3 and control group after day 2, but there was statistical difference between group 4 and control group at day 2(p<0.05). 3. Urinary fluoride concentration increased and plateaued according to increasing fluoride dosage. The increased concentration remained significantly higher till day 2, but after day 3, there was no significant difference compared to the control.

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Bacterial Stripe of Proso Millet Caused by Acidovorax avenae subsp. avenae in Korea (Acidovorax avenae subsp. avenae에 의한 기장 세균성줄무늬병)

  • Yoon, Young-Nam;Jung, Ji-Hun;Lee, Yeong-Hoon;Kim, Hyun-Joo;Bae, Soon-Do;Choi, Byeong-Ryeol;Nam, Min-Hee;Lee, Young-Kee
    • Research in Plant Disease
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    • v.18 no.3
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    • pp.236-239
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    • 2012
  • In July, 2009, proso millet (Panicum miliaceum), which showing the bacterial brown stripes on leaf sheaths, was collected in Miryang in Korea. Symptoms were systemic brown necrotic stripe lesions on the leaf sheaths and stems, and these symptoms were found in the entire field. The causal agent isolated from symptomatic plants was identified as an Acidovorax avenae subsp. avenae, based on its biochemical and physiological characteristics and also confirmed by the Biolog data and 16S rRNA gene sequence analysis. Also it caused hypersensitive response (HR) when it was inoculated onto the tobacco and tomato. It caused similar symptoms when inoculated onto proso millet. This is the first report of A. avenae subsp. avenae, the causal agent of bacterial brown stripe of the proso millet in Korea.

Radiation recall dermatitis triggered by sorafenib after radiation therapy for hepatocellular carcinoma

  • Kim, Gwi Eon;Song, Hee-Sung;Ahn, Ki Jung;Kim, Young Suk
    • Radiation Oncology Journal
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    • v.35 no.3
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    • pp.289-294
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    • 2017
  • Sorafenib is widely used for unresectable and metastatic hepatocellular carcinomas. Radiation recall dermatitis (RRD) is an acute inflammatory reaction confined to previously irradiated skin that occurs after the administration of certain drugs. RRD after sorafenib treatment is rare; five cases have been reported thus far. We describe a 44-year-old man irradiated for chest wall bone metastasis from hepatocellular carcinoma. Eight days after radiotherapy completion, systemic therapy for metastatic hepatocellular carcinoma was initiated with sorafenib treatment. Eleven days after starting sorafenib, the patient complained of erythematous rash with pruritus in the chest wall, in a location consistent with the previous radiation field. Sorafenib was continued at the same dose, despite the RRD. The skin reaction subsided over the next 2 weeks without any medical intervention.

Systemic effects of multidose hypothermic potassium cardioplegia: an experimental study in six dogs (냉혈 K 심정지액의 반복사용시 전신적인 영향동물실험 6)

  • 기노석
    • Journal of Chest Surgery
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    • v.17 no.4
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    • pp.587-592
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    • 1984
  • Potassium cardioplegia for myocardial preservation is being used extensively in open heart surgery. This study was designed to investigate the change in serum and urine potassium before, during, after the administration of cold blood potassium cardioplegic solution containing 28-30 mEq/L [28.6\ulcorner.56 mEq/L] of potassium chloride in 6 dogs. Total potassium dose used in the study was 14.9\ulcorner.89 mEq/L [1.2 mEq/Kg]. Mean potassium level in serum was within normal limits. Urinary excretion of potassium decreased during bypass but increased after bypass and eventually exceeded the amount of potassium infused as cold blood potassium cardioplegic solution. While cold blood potassium cardioplegia is a safe and efficient method of myocardial protection, postoperative potassium level must be observed carefully in order to detect obligatory potassium excretion following open heart surgery.

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Skin Permeation of Flurbiprofen through Excised Rat Skin from Poloxamer 407 Gel

  • Gil, Hyung-Jun;Lee, Woo-Young;Chi, Sang-Cheol
    • Journal of Pharmaceutical Investigation
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    • v.24 no.3
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    • pp.27-32
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    • 1994
  • In order to reduce systemic side effects following oral administration, flurbiprofen was formulated as transdermal gels consisting of the drug, poloxamer 407 and ethanol in buffer solutions. The effect of formulation variables in the preparation of flurbiprofen gels on skin permeation of the drug was evaluated using Keshary-Chien diffusion cells fitted with excised rat skins. The permeation rate of flurbiprofen through rat skin was directly proportional to initial drug concentration (between 0.1% and 1.0%) in the gel while it was inversely proportional to poloxamer 407 concentration (between 17.5% and 25%). The skin permeation of flurbiprofen was substantially influenced by the gel pH between 3 and 7, exhibiting a maximum at pH 4. The concentration effect of ethanol on the permeation of the drug was negligible in the concentration range of $10{\sim}20%$.

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Spinal Epidural Lipomatosis in Korean

  • Yoo, Je Chul;Choi, Jeong Jae;Lee, Dong Woo;Lee, Sang Pyung
    • Journal of Korean Neurosurgical Society
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    • v.55 no.6
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    • pp.365-369
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    • 2014
  • Spinal epidural lipomatosis (SEL) is a rare disorder, regarded in literature as a consequence of administration of exogenous steroids, associated with a variety of systemic diseases, endocrinopathies and the Cushing's syndrome. Occasionally, SEL may occur in patients not exposed to steroids or suffering from endocrinopathies, namely, idiopathic SEL. Thus far, case studies of SEL among Korean have been published rather sporadically. We reviewed the clinical features of SEL cases, among Koreans with journal review, including this report of three operated cases. According to this study, there were some differences between Korean and western cases. Koreans had higher incidences of idiopathic SEL, predominant involvement in the lumbar segments, very few thoracic involvement and lower MBI, as opposed to westerners.

A Study on the Successful Factors in the Application of RIMS Project for the Safe Operation of Rolling Stocks in the Public Transportation (공공교통 전동차 안전운행을 위한 RIMS 프로젝트 적용의 성공요인 연구)

  • Lee, Kang-Won;Bhang, Youn-Keun;Son, Young-Jin
    • Journal of the Korean Society for Railway
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    • v.9 no.5 s.36
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    • pp.555-560
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    • 2006
  • This study finds out and suggests success factors for the application of RIMS project through the case study of Seoul Metro and literature survey. The successful application of RIMS needs expert knowledge and concept of BOM, standardization of maintenance planning, check lists of heavy maintenance inspection, organization structure of rolling stock maintenance offices, material management system of warehousing and the process of parts repairing between offices, connection of material ordering system, problem solving of circular spare parts administration among inspection, maintenance, and material organizational units, systemic serial number management of parts with RFID, daily closing diary connected with work process chart, and sufficient period of RIMS's test run. RIMS contributes to real time management of rolling stock maintenance, transparency of management, reliability of train operation, customer satisfaction, and management innovation.

Pulmonary Mcosis (폐진균증)

  • 임병화;홍완일;김의윤
    • Journal of Chest Surgery
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    • v.6 no.1
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    • pp.29-36
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    • 1973
  • It has been known that the pulmonary mycosis generally results from saphrophytic colonization of pre-existing lung cavities, e.g. , due to pulmonary tuberculosis, abscess, bronchiectasis. or congen-ital cysts. Recently, the authors experienced four cases of the pulmonary mycosis which were all treated surgically, and in our opinion, three of them were considered to arise from secondary saphrophytic colonization of pre-existing tuberculous cavities by serial chest roentgenograms. One of them was actinomycosis which was known as relatively rare pulmonary mycosis, and its clinical experience was previously reported. The purpose of this report is mainly to review our clinical experience and some related literatures with three patients with aspergillosis. Many writers have stressed the sputum culture for aspergillus, immunologic study and serial roentgenographic findings were all important or essential in diagnosing aspergillosis. Surgical resection appears to be the treatment of choice for the mycosis of lung, and systemic administration of effective anti-fungal agents such as amphotericin B for aspergillosis and penicillin for actinomycosis respectively following surgical intervention is usually necessary to eradicate completely.

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