• 제목/요약/키워드: synthetic variety

검색결과 209건 처리시간 0.025초

아크릴산이 그라프트된 나노섬유에서의 폴리도파민 코팅 (Polydopamine Coating Behaviors on the Acrylic Acid Grafted-Nanofibers)

  • 신영민;김우진;박종석;권희정;노영창;임윤묵
    • 방사선산업학회지
    • /
    • 제5권4호
    • /
    • pp.371-376
    • /
    • 2011
  • The surface property of the materials used in tissue engineering application has been essential to regulate cellular behaviors by directing their adhesion on the materials. To modulate surface property of the synthetic biodegradable materials, a variety of surface modification techniques have used to introduced surface functional groups or bioactive molecules, recently polydopamine coating method have been introduce as a facile modification method which can be coated on various materials such as polymers, metals, and ceramics regardless of their surface property. However, there are no reports about the degree of polydopamine coating on the materials with different hydrophilicity. In the present study, we prepared acrylic acid grafted nanofibrous meshes using electron-beam irradiation, and then coated meshes with polydopamine. Polydopamine successfully coated on the all meshes, both properties of acrylic acid and polydopamine were detected on the meshes. In addition, the degree of polydopamine deposition on the materials has been altered according to surface hydrophilicity, which was approximately 8-times greater than those on the non-modified materials. In conclusion, dual effect from the acrylic acid grafting and polydopamine may give a chance as a alternative tool in tissue engineering application.

비행체의 전자파 영상화 기술동향 (A Perspective on the Electromagnetic Imaging of Aircrafts)

  • 윤용수;이재천
    • 대한원격탐사학회지
    • /
    • 제15권3호
    • /
    • pp.167-175
    • /
    • 1999
  • 원격탐사 관련 핵심기술은 최근에 국방, 의료영상, 환경, 지질 등과 같은 광범위한 분야에서 활용범위를 확대하고 있다. 1cm ~ 수십 cm 파장의 파를 관측하는 마이크로파 원격탐사 기술은 반사 적외선 원격탐사나 열 적외선 원격탐사 기술에 비해 날씨조건과 밤낮에 관계없이 탐사를 수행할 수 있다는 장점을 가지고 있다. 마이크로파 영상레이다인 합성 개구 레이다를 이용한 영상화 방식은 응용목적에 따라 stripmap 방식, spotlight 방식, 그리고 inverse 방식으로 구분된다. 본 논문에서는 inverse 방식으로 지상에 고정된 레이다가 비행하는 항공체를 영상화하는 기법에 대해서 기술하였다. 비행 항공체의 영상화 기법은 자동 펴적인식 시스템 구축시 중요한 기술단계이며, 최근 이 분야에 대해 활발히 연구되고 있다. 비행 항공체를 영상화하기 위해 제안된 3가지 방식인 퓨리에 처리 기법, 시간-n 주파수 처리 기법, 그리고 투시로부터 복원 기법을 소개한 후, 각 방식의 장단점을 분석하였다.

HPLC를 활용한 천연염료 적합성 평가 연구 (1) (A Study for the Conformity Assessment on the Natural Dye by HPLC (1))

  • 이은미;오동기;윤홍진;김종훈
    • 한국의류산업학회지
    • /
    • 제20권6호
    • /
    • pp.752-758
    • /
    • 2018
  • Due to environmental pollution and human hazards of some synthetic dyes, the global fashion companies are increasingly interested in eco-friendly products, especially natural dye. For the globalization of natural dyeing industry based on this concern, however, there are some deficiencies of standardization, specification, and conformity assessment on natural dyestuffs as well as natural dyeing process. These obstacles should be not only studied but also defined for a commercial transaction. Accordingly, a study for conformity assessment on commercialized natural dyestuffs (red) was conducted by HPLC analysis in this study. As the results of HPLC analysis, alizarin and purpurin, representative index ingredients, were detected in most of the samples, but the index ingredient content in each sample was different. In addition, some samples showed the variety of peaks including the index ingredients and others. It was inferred that the representative index ingredients could be used on the traceability of natural sourced dyestuffs. These results are related to the index ingredient consistency, standardization, and reproducibility of natural dyed products including such as yarns, fabrics, garments, and so on. Therefore, the present study was demonstrated that in order to determine the conformity assessment system for the satisfaction of all stakeholders, the offering of information on the origin, manufacturing process, and index ingredient content of natural dyes should be prioritized.

Heterologous Expression and Characterization of a Laccase from Laccaria bicolor in Pichia pastoris and Arabidopsis thaliana

  • Wang, Bo;Yan, Ying;Xu, Jing;Fu, Xiaoyan;Han, Hongjuan;Gao, Jianjie;Li, Zhenjun;Wang, Lijuan;Tian, Yongsheng;Peng, Rihe;Yao, Quanhong
    • Journal of Microbiology and Biotechnology
    • /
    • 제28권12호
    • /
    • pp.2057-2063
    • /
    • 2018
  • Laccases can oxidize a variety of phenolic and non-phenolic substrates including synthetic dyes. In this research, a laccase gene Lcc9 from Laccaria bicolor was chemically synthesized and optimized to heterogeneous expression in Pichia pastoris and Arabidopsis thaliana. The properties of recombinant laccase expressed by P. pastoris were investigated. The laccase activity was optimal at 3.6 pH and $40^{\circ}C$. It exhibited $K_m$ and $V_{max}$ values of $0.565mmol\;l^{-1}$ and $1.51{\mu}mol\;l^{-1}\;min^{-1}$ for ABTS respectively. As compared with untransformed control plants, the laccase activity in crude extracts of transgenic lines exhibited a 5.4 to 12.4-fold increase. Both laccases expressed in transgenic P. pastoris or A. thaliana could decolorize crystal violet. These results indicated that L. bicolor laccase gene may be transgenically exploited in fungi or plants for dye decolorization.

자력선별장비의 유형과 활용 (Application and Type of Magnetic Separator)

  • 이상훈;양인재;최승진;박제현
    • 자원리싸이클링
    • /
    • 제27권6호
    • /
    • pp.11-22
    • /
    • 2018
  • 자력선별장비는 일반적으로 광산업 및 재활용 분야에서 사용되어 왔으며, 다양한 분야에서 폭넓게 활용되고 있다. 자력선별장비는 비철재료로부터 철 스크랩 분리를 위한 조립자용 선별장비와 3 mm 이하 미립 강자성체를 농축하기 위한 미립자용 선별장비로 구분된다. 또한 미립자용 선별장비는 저자력 선별장비와 고자력 선별장비로 세분된다. 저자력 선별장비는 강자성체나 높은 자화율의 상자성체를 분리하는데 사용되고, 고자력선별장비는 낮은 자화율의 상자성체를 분리하는데 사용된다. 저자력 및 고자력 선별장비 모두 습식과 건식으로 활용된다. 최근 0.7 Tesla미만 영역에서 활용되는 전자석 고구배자력선별장비는 1980년대 이후 상용화된 희토류 영구자석으로 제조된 자력선별장비로 점진적으로 대체되는 추세이며, 환경분야와 생물분야에서 합성자성물질과 관련된 나노기술의 확대는 향 후 자력선별기술의 발전에 긍정적으로 기여할 것으로 기대된다.

다목적실용위성 영상자료 활용 현황 (KOMPSAT Imagery Application Status)

  • 이광재;김윤수;채태병
    • 대한원격탐사학회지
    • /
    • 제34권6_3호
    • /
    • pp.1311-1317
    • /
    • 2018
  • 위성개발의 궁극적인 목적은 위성으로부터 획득되는 정보의 활용에 있다. 따라서 국가 차원의 위성개발 프로그램은 하드웨어 개발뿐만 아니라 정보 활용을 위한 인프라 구축 및 활용기술 개발도 포함하여야 한다. 지금까지 우리나라는 다양한 위성을 개발하여 기상 및 해양 감시를 비롯하여 각종 재해재난 등에 있어 매우 유용하게 활용해 왔다. 특히 다목적실용위성 영상은 높은 공간해상도를 바탕으로 농업, 산림분야를 비롯하여 해양 분야까지 폭 넓게 활용되어 왔으며, 최근에는 정밀 지도제작 및 변화탐지 등과 관련된 연구에 많이 이용되고 있다. 본 특별호는 최근 다목적실용위성 광학 및 레이더 영상을 활용하여 수행된 다양한 연구사례에 대해서 소개함과 동시에 관련 위성영상 활용기술을 공공부문으로 전파시키는데 목적이 있다.

Water-stable solvent dependent multicolored perovskites based on lead bromide

  • Sharipov, Mirkomil;Hwang, Soojin;Kim, Won June;Huy, Bui The;Tawfik, Salah M.;Lee, Yong-Ill
    • Advances in nano research
    • /
    • 제13권2호
    • /
    • pp.187-197
    • /
    • 2022
  • The synthesis of organic and hybrid organic-inorganic perovskites directly from solution improves the cost- and energy-efficiency of processing. To date, numerous research efforts have been devoted to investigating the influence of the various solvent parameters for the synthesis of lead halide perovskites, focused on the effects of different single solvents on the efficiency of the resulting perovskites. In this work, we investigated the effect of solvent blends for the first time on the structure and phase of perovskites produced via the Lewis base vapor diffusion method to develop a new synthetic approach for water-stable CsPbBr3 particles with nanometer-sized dimensions. Solvent blends prepared with DMF and water-miscible solvents with different Gutmann's donor numbers (DN) affect the Pb ions differently, resulting in a variety of lead bromide species with various colors. The use of a DMF/isopropanol solvent mixture was found to induce the formation of the Ruddlesden-Popper perovskite based on lead bromide. This perovskite undergoes a blue color shift in the solvated state owing to the separation of nanoplatelets. In contrast, the replacement of isopropanol with DMSO, which has a high DN, induces the formation of spherical CsPbBr3 perovskite nanoparticles that exhibit green emission. Finally, the integration of acetone in the solvent system leads to the formation of lead bromide complexes with a yellow-orange color and the perovskite CsPbBr3.

영상 생성적 데이터 증강을 이용한 딥러닝 기반 SAR 영상 선박 탐지 (Deep-learning based SAR Ship Detection with Generative Data Augmentation)

  • 권형준;정소미;김성태;이재석;손광훈
    • 한국멀티미디어학회논문지
    • /
    • 제25권1호
    • /
    • pp.1-9
    • /
    • 2022
  • Ship detection in synthetic aperture radar (SAR) images is an important application in marine monitoring for the military and civilian domains. Over the past decade, object detection has achieved significant progress with the development of convolutional neural networks (CNNs) and lot of labeled databases. However, due to difficulty in collecting and labeling SAR images, it is still a challenging task to solve SAR ship detection CNNs. To overcome the problem, some methods have employed conventional data augmentation techniques such as flipping, cropping, and affine transformation, but it is insufficient to achieve robust performance to handle a wide variety of types of ships. In this paper, we present a novel and effective approach for deep SAR ship detection, that exploits label-rich Electro-Optical (EO) images. The proposed method consists of two components: a data augmentation network and a ship detection network. First, we train the data augmentation network based on conditional generative adversarial network (cGAN), which aims to generate additional SAR images from EO images. Since it is trained using unpaired EO and SAR images, we impose the cycle-consistency loss to preserve the structural information while translating the characteristics of the images. After training the data augmentation network, we leverage the augmented dataset constituted with real and translated SAR images to train the ship detection network. The experimental results include qualitative evaluation of the translated SAR images and the comparison of detection performance of the networks, trained with non-augmented and augmented dataset, which demonstrates the effectiveness of the proposed framework.

Transcriptional Regulatory Role of NELL2 in Preproenkephalin Gene Expression

  • Ha, Chang Man;Kim, Dong Hee;Lee, Tae Hwan;Kim, Han Rae;Choi, Jungil;Kim, Yoonju;Kang, Dasol;Park, Jeong Woo;Ojeda, Sergio R.;Jeong, Jin Kwon;Lee, Byung Ju
    • Molecules and Cells
    • /
    • 제45권8호
    • /
    • pp.537-549
    • /
    • 2022
  • Preproenkephalin (PPE) is a precursor molecule for multiple endogenous opioid peptides Leu-enkephalin (ENK) and Met-ENK, which are involved in a wide variety of modulatory functions in the nervous system. Despite the functional importance of ENK in the brain, the effect of brain-derived factor(s) on PPE expression is unknown. We report the dual effect of neural epidermal growth factor (EGF)-like-like 2 (NELL2) on PPE gene expression. In cultured NIH3T3 cells, transfection of NELL2 expression vectors induced an inhibition of PPE transcription intracellularly, in parallel with downregulation of protein kinase C signaling pathways and extracellular signal-regulated kinase. Interestingly, these phenomena were reversed when synthetic NELL2 was administered extracellularly. The in vivo disruption of NELL2 synthesis resulted in an increase in PPE mRNA level in the rat brain, suggesting that the inhibitory action of intracellular NELL2 predominates the activation effect of extracellular NELL2 on PPE gene expression in the brain. Biochemical and molecular studies with mutant NELL2 structures further demonstrated the critical role of EGF-like repeat domains in NELL2 for regulation of PPE transcription. These are the first results to reveal the spatio-specific role of NELL2 in the homeostatic regulation of PPE gene expression.

The roles of growth factors and hormones in the regulation of muscle satellite cells for cultured meat production

  • Syed Sayeed Ahmad;Hee Jin Chun;Khurshid Ahmad;Sibhghatulla Shaikh;Jeong Ho Lim;Shahid Ali;Sung Soo Han;Sun Jin Hur;Jung Hoon Sohn;Eun Ju Lee;Inho Choi
    • Journal of Animal Science and Technology
    • /
    • 제65권1호
    • /
    • pp.16-31
    • /
    • 2023
  • Cultured meat is a potential sustainable food generated by the in vitro myogenesis of muscle satellite (stem) cells (MSCs). The self-renewal and differentiation properties of MSCs are of primary interest for cultured meat production. MSC proliferation and differentiation are influenced by a variety of growth factors such as insulin-like growth factors (IGF-1 and IGF-2), transforming growth factor beta (TGF-β), fibroblast growth factors (FGF-2 and FGF-21), platelet-derived growth factor (PDGF) and hepatocyte growth factor (HGF) and by hormones like insulin, testosterone, glucocorticoids, and thyroid hormones. In this review, we investigated the roles of growth factors and hormones during cultured meat production because these factors provide signals for MSC growth and structural stability. The aim of this article is to provide the important idea about different growth factors such as FGF (enhance the cell proliferation and differentiation), IGF-1 (increase the number of myoblasts), PDGF (myoblast proliferation), TGF-β1 (muscle repair) and hormones such as insulin (cell survival and growth), testosterone (muscle fiber size), dexamethasone (myoblast proliferation and differentiation), and thyroid hormones (amount and diameter of muscle fibers and determine the usual pattern of fiber distributions) as media components during myogenesis for cultured meat production.