• Title/Summary/Keyword: susceptibility effect

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The Relation Between Temperament and Accumulated Cortisol Levels Among Toddlers Following Childcare Use (영아의 기질과 누적 코티솔 수준의 관계: 어린이집 이용 여부에 따른 차이)

  • Song, Ji-Na;Yi, Soon-Hyung
    • Korean Journal of Child Studies
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    • v.37 no.3
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    • pp.1-12
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    • 2016
  • Objective: This study aimed to examine the difference in toddlers' accumulated cortisol levels based on childcare experience in toddlerhood and the relationship between temperament and accumulated cortisol levels. Methods: Hair sample were collected for measure accumulated cortisol level in 87 toddlers. The Early Childhood Behavior Questionnaire (ECBQ) was used to measure temperament. Results: First, toddlers in childcare showed higher accumulated cortisol levels than in-home toddlers. Second, toddlers in childcare, exhibited a significant correlation between accumulated cortisol levels and surgency. Third, the accumulated cortisol levels of in-home toddlers exhibited a significant correlation with negative affect. In this research, there was significant range in the accumulated cortisol level according to childcare use, and the factors related to accumulated cortisol levels were different in each context. Conclusion: The results of this research support the "susceptibility to context of HPA axis" and imply a needed discussion about the effect of childcare experiences in toddlerhood.

Effects of Human Papillomavirus Vaccination Education on College Women's Knowledge, Health Belief, and Preventive Behavior Intention (여대생에게 실시한 인유두종 바이러스 예방접종 교육의 효과)

  • Lee, Eun-Jee;Kim, Hyeon-Ok
    • Journal of Korean Academy of Nursing
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    • v.41 no.5
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    • pp.715-723
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    • 2011
  • Purpose: This study was done to evaluated the effects of Human Papillomavirus (HPV) vaccination education on college women's knowledge of HPV, health beliefs (perceived severity and perceived susceptibility), and preventive behavior intention. Methods: A nonequivalent control group pretest-posttest design with repeated measures was used. Participants were 125 female college students in one university, assigned to an experimental group (72 students) and control group (53 students). Results: Two weeks after the intervention, the experimental group reported higher scores of knowledge, perceived severity, perceived susceptibility, and preventive behavior intention than the control group. All follow-up scores except intention measured at 5 weeks after the intervention from the experimental group remained still higher than those from the control group. Conclusion: The results suggest that the variable of preventive behavior intention which is believed to be the closest predictor of real vaccination rate could be affected by the education, but did not remain at the same level at 5 weeks. Therefore, additional interventions may need to be provided before the educational effect on preventive behavior intention is greatly diminished.

Nutritional Effects on the Environmental Health (영양과 환경과의 관계)

  • 문현경
    • Journal of environmental and Sanitary engineering
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    • v.6 no.2
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    • pp.17-31
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    • 1991
  • The effects of environmental agents on health are great concern for all. It was recognized that each human has differential susceptibility to environmental effects. Susceptibility are changed by many factors includin gdevelopmpntal processes, genetic factors, nutritional stratus, preexisting disease conditions, life style and personal habits. Of all factors nutritional factors seem to be the area most modifiable. Consequently, It is an area that must be more thoroughly evaluated. In this paper, nutrient and environment interactions are reviewed briefly with published literatures. This paper deals with the influence of micronutrients(energy, protein and fat), Vitamins (vitamin 4, vitamin B-complex, vitamin C, vitamin D and vitamin I) and Minerals(calcium, iron, selenium, zinc and other minerls) on environmental effects. The role of arch nutrient was assessed in modifyine the expression of environmental pollutant toxicity with available litertures. In each nutrient section, the effect of environment was considered in following agents : heavy metals(lead, cadmium, mercury, silver and etc), inorganic agents(nitwits, sulfite, fluoride and etc), organic agents(benzene, carbon tatra-chloride, aflatoxin, auto dye, dialbrin etc), Irritant gas(ozone, carbon monooxide and etc), physical agents(X-irradiation, ultra violet, temperature and noise) and insectcides. The extent to which nutritional status modifies environmental effects 3nd its converse, how envirollments affects nutritional status is very complex. In deed, at the present time there are more than 50 chelnical/phycical agents that affect the nutrient metabolism and/or have their toxicity either directly diminished or enhanced by nutrients of those agents, small number of agents for each nutrients have sufficient evidence to warrant any reasonable degree of confidence in their hypothesized associtation. With these information at this present time it is hard to conclude that the recommended dietary allowance for each nutrient should be reconsidered.

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Mitochondrial Porin Isoform AtVDAC1 Regulates the Competence of Arabidopsis thaliana to Agrobacterium-Mediated Genetic Transformation

  • Kwon, Tackmin
    • Molecules and Cells
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    • v.39 no.9
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    • pp.705-713
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    • 2016
  • The efficiency of Agrobacterium-mediated transformation in plants depends on the virulence of Agrobacterium strains, the plant tissue culture conditions, and the susceptibility of host plants. Understanding the molecular interactions between Agrobacterium and host plant cells is crucial when manipulating the susceptibility of recalcitrant crop plants and protecting orchard trees from crown gall disease. It was discovered that Arabidopsis voltage-dependent anion channel 1 (atvdac1) mutant has drastic effects on Agrobacterium-mediated tumorigenesis and growth developmental phenotypes, and that these effects are dependent on a Ws-0 genetic background. Genetic complementation of Arabidopsis vdac1 mutants and yeast porin1-deficient strain with members of the AtVDAC gene family revealed that AtVDAC1 is required for Agrobacterium-mediated transformation, and there is weak functional redundancy between AtVDAC1 and AtVDAC3, which is independent of porin activity. Furthermore, atvdac1 mutants were deficient in transient and stable transformation by Agrobacterium, suggesting that AtVDAC1 is involved in the early stages of Agrobacterium infection prior to transferred-DNA (T-DNA) integration. Transgenic plants overexpressing AtVDAC1 not only complemented the phenotypes of the atvdac1 mutant, but also showed high efficiency of transient T-DNA gene expression; however, the efficiency of stable transformation was not affected. Moreover, the effect of phytohormone treatment on competence to Agrobacterium was compromised in atvdac1 mutants. These data indicate that AtVDAC1 regulates the competence of Arabidopsis to Agrobacterium infection.

Geophysical Applications on the Soil-contamination Mapping and Detection of Buried Mine Tailings in the Abandoned Mine Area (폐광산의 토양오염영역 및 폐기된 광미의 탐지)

  • Lee, Sang Kyu;Hwang, Se Ho;Lee, Tai Sup
    • Economic and Environmental Geology
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    • v.30 no.4
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    • pp.371-377
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    • 1997
  • This paper presents the geophysical applications to the environmenml problem in an abandoned mine area. We would like to focus our attention on the mapping of the soil contamination and the detection of the buried mine tailings. For mapping the soil contamination. measurements of both in-situ magnetic susceptibility (k) and terrain conductivity were carried out. In-situ magnetic susceptibilities of the contaminated soil due to the acid mine drainage show higher values than those of the uncontaminated area. However. those data do not show the correlation with the degree of the soil contamination observed on the surface. The least-squares fitted formula obtained with the measured insitu magnetic susceptibilities is $k=4.8207{\times}W^{0.6332}$, where W is the $Fe^{+2}$ weight percentage. This weight gives most effect to magnetic susceptibility of the soil. Lateral variations of the soil contamination in the shallow subsurface can be detected by the electrical conductivity distributions from EM induction survey. TDIP (Time Domain Induced Polarization) and EM induction surveys were conducted to detect the buried mine tailings. From the results of TDIP, the spatial zone, which shows high chargeability-low resistivity, is interpreted as the buried mine tailings. Therefore, it is concluded that it is possible to discriminate the spatial zone from the uncontaminated ground.

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Cooperativity of the Interaction of Nucleohistone and DNase 1, and Effects of Spermine and Dansylation on It (Nucleohistone과 DNase 1 과의 相互作用의 Cooperativity 및 이에 미치는 Spermine과 Dansylation 效果)

  • Chan Yong Lee;Ko Thong Sung
    • Journal of the Korean Chemical Society
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    • v.29 no.3
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    • pp.304-310
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    • 1985
  • Effect of spermine on the susceptibility of calf thymus nucleohistone to DNase 1, in relation to the structural change of the nucleohistone, and cooperativity of the interaction of the nucleohistone with DNase 1 was investigated. Dansylated nucleohistone, in which the histone moiety had been derivatized by dansylation, was also used to investigate functional roles of the histone moiety on the cooperativity. The data here indicate the possibility that the nucleohistone, in contrast with the DNA, may not undergo monomolecular condensation, whereas intermolecular aggregation and enhancement of the positive cooperativity of the interaction of nucleohistone with DNase 1 may be brought about by spermine. The interaction of the DNS-nucleohistone with DNase 1 showed negative cooperativity. Based on the data here, it can be speculated that the cooperativity of the nucleohistone is influenced by the histone moiety of the nucleohistone.

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Growth, Morphology, Cross Stress Resistance and Antibiotic Susceptibility of K. pneumoniae Under Simulated Microgravity

  • Kalpana, Duraisamy;Cha, Hyo-Jung;Park, Moon-Ki;Lee, Yang-Soo
    • Journal of Environmental Science International
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    • v.21 no.3
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    • pp.267-276
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    • 2012
  • Spaceflights results in the reduction of immune status of human beings and increase in the virulence of microorganisms, especially gram negative bacteria. The growth of Klebsiella pneumoniae is enhanced by catecholamines and during spaceflight, elevation in the levels of cortisols occurs. So it is necessary to know the changes in physiology, virulence, antibiotic resistance and gene expression of K. pneumoniae under microgravity conditions. The present study was undertaken to study effect of simulated microgravity on growth, morphology, antibiotic resistance and cross stress resistance of K. pneumoniae to various stresses. The susceptibility of simulated microgravity grown K. pneumoniae to ampicillin, penicillin, streptomycin, kanamycin, hygromycin and rifampicin were evaluated. The growth of bacteria was found to be fast compared with normal gravity grown bacteria and no significant changes in the antibiotic resistance were found. The bacteria cultured under microgravity conferred cross stress resistance to acid, temperature and osmotic stress higher than the normal gravity cultured bacteria but the vice versa was found in case of oxidative stress.

Effect of Peak Temperatures on Hydrogen Attack Susceptibility in Simulated Weld Heat Affected Zone of 3Cr-1Mo-V Steel (3Cr-1Mo-V강의 재현 열영향부에서 최고가열온도가 수소침식감수성에 미치는 영향)

  • 김동진;김병훈;공병욱;김정태;권용형;박화순;강정윤
    • Journal of Welding and Joining
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    • v.18 no.2
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    • pp.232-232
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    • 2000
  • The hydrogen attack characteristics of 3Cr-1Mo-V steel as simulated weld heat affected state were studied in this paper. The hydrogen attack susceptibility was evaluated by the ratios of Charpy impact absorbed energy at 0℃($vE_{0HA}$/$vE_{0}$) and reduction of area by tensile test ($RA_{HA}$/RA) before and after exposure to hydrogen at 600℃ under 450kgf/㎠ for 300hr. The values of $vE_{0HA}$/$vE_{0}$ and $RA_{HA}$/RA were aggravated as the peak temperature of the simulated heat affected zone(HAZ) raised. These results were due to the increase of the possession of bubbles along the grain boundaries, which were resulted in the reduction of grain boundary area to be precipitated carbides due to grain coarsening and the carbon dissolved in the martensite-austenite constituent near by the prior austenite grain boundary. The possession ratio of methane bubbles formed along prior austenite grain boundaries were increased with raising the peak temperature. (Received February 22, 2000)

Effect of Peak Temperatures on Hydrogen Attack Susceptibility in Simulated Weld Heat Affected Zone of 3Cr-1Mo-V Steel (3Cr-1Mo-V강의 재현 열영향부에서 최고가열온도가 수소침식감수성에 미치는 영향)

  • 김동진;김병훈;공병욱;김정태;권용형;박화순;강정윤
    • Journal of Welding and Joining
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    • v.18 no.2
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    • pp.105-111
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    • 2000
  • The hydrogen attack characteristics of 3Cr-1Mo-V steel as simulated weld heat affected state were studied in this paper. The hydrogen attack susceptibility was evaluated by the ratios of Charpy impact absorbed energy at 0℃({TEX}$vE_{0} {HA}_/vE_{0}${/TEX}) and reduction of area by tensile test({TEX}$RA_{HA}/RA${/TEX}) before and after exposure to hydrogen at 600℃ under 450kgf/㎠ for 300hr. The values of {TEX}$vE_{0} {HA}_/vE_{0}${/TEX} and {TEX}$RA_{HA}/RA${/TEX} were aggravated as the peak temperature of the simulated heat affected zone(HAZ) raised. These results were due to the increase of the possession of bubbles along the grain boundaries, which were resulted in the reduction of grain boundary area to be precipitated carbides due to grain coarsening and the carbon dissolved in the martensite-austenite constituent near by the prior austenite grain boundary. The possession ratio of methane bubbles formed along prior austenite grain boundaries were increased with raising the peak temperature.

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Effect of cement as mineral filler on the performance development of emulsified asphalt concrete

  • Liu, Baoju;Wu, Xiang;Shi, Jinyan;Wu, Xiaolong;Jiang, Junyi;Qin, Jiali
    • Advances in concrete construction
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    • v.10 no.6
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    • pp.515-526
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    • 2020
  • Cold-mixed asphalt mixture is a widely recommended asphalt pavement materials with potentially economic and environmental benefits. Due to the reduction of natural non-renewable mineral resources, powder minerals with similar properties are considered as new mineral fillers in asphalt mixtures. This study explored the feasibility of using cement to replace natural limestone powder (LP) in emulsified asphalt concrete modified by styrene-butadiene styrene copolymer. The experimental tests, including compressive strength, Marshall stability as well as moisture susceptibility test, were used to investigate the mechanical properties, the Marshall stability, flow value, as well as the moisture damage. In addition, the influence of material composition on the performance of asphalt concrete is explained by the microstructure evolution of the pore structure, the interface transition zone (ITZ), and the micromorphology. Due to mineralogical reactivity of cement, its replacement part of LP improved the mechanical properties, Marshall stability, but it will reduce the moisture susceptibility and flow value. This is because with the increase of the cement substitution rate, the pore structure of the asphalt concrete is refined, the width of ITZ becomes smaller, and the microstructure is more compact. In addition, asphalt concrete with a larger nominal particle size (AC-16) has relatively better performance.