• Title/Summary/Keyword: susceptibility effect

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Effect of Culture Medium on Results of Maerobroth Dilution Antifungal Susceptibility Testing of Candida albicans (Candida albicans의 시험관 희석법에 의한 항균력 검사시 배지가 항균력에 미치는 영향)

  • Koh, Choon-Myung;Kim, Soo-Ki
    • The Journal of the Korean Society for Microbiology
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    • v.22 no.3
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    • pp.301-307
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    • 1987
  • A total of 42 strains of Candida albicans were examined for susceptibility to three antifungal agents, amphotericin B(AMB), 5-fluorocytosine(5-FC), and ketoconazole(KTZ), using defined medium, synthetic amino acid medium-fungal(SAAM-F), supplemented yeast nitrogen base(SYNB) and undefined medium Sabouraud's dextrose broth(SDB) and Kimmig broth media. A tube dilution method was used with minimum inhibitory concentrations(MICs) determined after incubation for 24 hour and 48 hours. All testes were performed in duplicate. In general, MICs were more reproducible after 48 hour of incubation. Forthermore, MICs determined after incubation for 48 hours were significantly higher than those determined after 24 hours. The actural MICs obtained with the different antifungal agents were clearly influenced by the test medium used. The rank order of AMB MICs according to the test medium was as follows: SAAM-F>SYNB>SDB>Kimmig broth. With 5-FC, the following pattern was observed: SYNB>SAAM-F>SDB>Kimmig borth. For ketoconazole, the MICs according to the test medium was SAAM-F>SDB>SYNB> Kimmig broth. In amphotericin B, the MICs mean value with the test medium was as follows: SDB, 0.24 mcg/ml; Kimmig broth, 0.29 mcg/ml; SYNB, 0.21 mcg/ml and SAAM-F, 0.15mcg/ml. The actural value of 5-FC was; SDB, 37.20 mcg/ml; Kimmig broth, 67.41mcg/ml; SYNB, 21.29 mcg/ml and SAAM-F, 24.61 mcg/ml and in ketoconazole, the MICs value was; SDB, 1.83 mcg/ml; Kimmig broth, 4.08 mcg/ml; SYNB, 1.95 mcg/ml and SAAM-F, 1.41 mcg/ml. The results of this investigation suggested that broth dilution susceptibility testing of yeast and yeast-like fungi are best performed with an incubation period of 48 hours. Furthermore, medium composition can significantly influence the results of such testing.

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Determination of Semen Quality and Antibacterial Susceptibility Pattern of Bacteria Isolated from Semen of Iraqi Subjects

  • Faisal, Anwer Jaber;Salman, Hamzah Abdulrahman
    • Microbiology and Biotechnology Letters
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    • v.49 no.4
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    • pp.587-593
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    • 2021
  • Infertility is a key issue affecting mood and behavior in men. Microorganisms are one of the primary etiological agents that may be associated with infertility. The objective of the present study was to identify bacterial causative agents from the semen of infertile subjects and determine the effect of bacterial infection on sperm quality, as well as determine the susceptibility of these bacteria to drugs. Forty semen samples from 30 infertile patients and 10 fertile individuals were collected. The pH, volume, motility, and concentration of semen were analyzed. The samples were processed and identified by biochemical testing using API identification kits. The antibiotic susceptibility pattern was determined using the disc diffusion method. Abnormal sperm quality was observed. The mean age of the individual and their sperm morphology, concentration, progressive motility, pH level, and pus cell content were 31.9 years, 2.7%, 10.4 million/ml, 27.3%, 8.3, and 5.7, respectively. Among the tested samples, oligoasthenozoospermia was found to show the highest occurrence, at 27/30 samples, followed by teratozoospermia, at 25/30 samples, and asthenozoospermia, at 22/30 samples. Of the tested infertile patients' sperm, 19, 6, and 5 isolates were identified as Escherichia coli, Klebsiella pneumonia, and Staphylococcus epidermidis, respectively. The results also revealed multi-drug resistance in the bacteria. Compared to that shown by the other tested antibiotics, amikacin showed higher activity against all isolated bacteria. However, the bacteria exhibited maximum resistance against gentamicin, cefotaxime, levofloxacin, and ampicillin. In conclusion, leukocytospermia and bacterial infections are possibly responsible for sperm abnormalities. Multi-drug resistant bacteria were detected. Gentamicin, cefotaxime, levofloxacin and ampicillin were shown the highest resistance, while amikacin was the most effective antimicrobial agent against the isolated bacteria.

A Study on the Effectiveness of Pet Naming Types Using Celebrity Endorser (유명인을 이용한 제품 애칭화 유형에 따른 소비자 반응 연구)

  • Kim, Hyejin;Cho, Chang-Hoan
    • The Journal of the Korea Contents Association
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    • v.17 no.1
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    • pp.532-549
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    • 2017
  • This study identifies the pet-name using the celebrity's endorser and the pet-naming effect by the subject of creating brand identity. For this study, pet-naming types are made up of 3 types(non pet-named/pet-naming by company intention/pet-naming by customer's word of mouth). As the results of this study, pet-naming types affects the perceived value. The perceived value has a perfect mediating effect between pet-naming types and consumer response. Also, the level of informative interpersonal influence has significant interaction effect between pet-naming types and perceived value. The research, therefore, reaches several important conclusions. First, when the pet-naming types were consisted, customer's brand identity creating phenomenon was included. Second, pet-naming types affects the confirmed perceived value which is the customer's view. Third, susceptibility to interpersonal influence was differently identified with normative interpersonal influences and informative interpersonal influences. Furthermore, this study analyzes the market's behavior trends, and in extend the progression of pet-name marketing.

Magnetic Susceptibilities of the Single Crystal Nd3Se4 (단결정 Nd3Se4의 자기감수율)

  • Cha, Jung-Won;Nahm, Kyun;Kim, Chul-Koo
    • Journal of the Korean Magnetics Society
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    • v.17 no.3
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    • pp.114-119
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    • 2007
  • The single crystal $Nd_3Se_4$ with the $bcc-Th_3P_4$ type structure is grown and the temperature dependent magnetic susceptibilities are measured between 4 K and 300 K. The experimental data are compared with the theoretically calculated susceptibilities which depend on the splitting energies of the $Nd^{3+}$ ground state under the crystal field effect. We find that the magnetic susceptibility of the $Nd^{3+}$ ion in $Nd_3Se_4$ is not affected by the crystal field effect. The spontaneous magnetization curve below $T_c\;=\;53\;K$ of $Nd_3Se_4$ corresponds to the Brillouin function of $Nd_3Se_4$ with J=9/2.

Differential Susceptibility of Tetranychus urticae and its Predator, Phytoseiulus persimilis (Acari: Tetranychidae, Phytoseiidae) against Individual and Combined Treatments of Plant Extracts (점박이응애와 포식성 천적인 칠레이리응애의 식물추출물 단독 및 혼합 처리에 대한 감수성 비교)

  • Lee, Chan-Joo;Kuk, Yong-In;Kim, Sang-Soo
    • Korean Journal of Organic Agriculture
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    • v.27 no.3
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    • pp.327-339
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    • 2019
  • The differential susceptibility of the two spotted spider mite, Tetranychus urticae and its predator, Phytoseiulus persimilis against extracts of Gleditsia japonica var. koraiensis, Camellia sinensis, Cinnamomum cassia, Lantana camara and their mixtures was evaluated. The plant extracts tested were much less toxic to P. persimilis than to T. urticae. The plant extracts tested had little effect on the survival of P. persimilis adult females. Moreover, reproduction of P. persimilis adult females and eclosion of eggs deposited by treated predators were not seriously affected. The treatments of the plant extracts tested showed no serious toxic effect on P. persimilis eggs and exhibited 84~100% hatchability. The treatments with mixtures 3 and 1 were effective against the adult females of T. urticae and yielded 76.0% and 72.7% adulticidal activity at 7 days after treatment, respectively. The treatment of mixture 2 revealed 63.3% adulticidal activity. Generally, the acaricidal activity of the individual treatment of each plant extract was lower than the mixtures. The adult females of T. urticae treated with mixtures 3 and 1 produced only 29.5~31.3% as many eggs as the control females did. All the plant extracts tested exhibited no noticeable toxic effect to the eggs of T. urticae. These results suggest that mixtures 3 and 1 might be used for the control of T. urticae, and expected to be promising candidates for use in integrated mite management program with P. persimilis.

The Effect of Pulmonary T.B. Patients Self-Concept and Health Beliefs on Therapeutic Behavior (폐결핵 환자의 자아개념 (Self-Concept)과 건강신념(Health Beliefs)이 치료적 행위 이행에 미치는 영향)

  • 심영옥
    • Journal of Korean Academy of Nursing
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    • v.13 no.3
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    • pp.61-74
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    • 1983
  • The proportion of people who contacted pulmonary T.B. in Korea has drastically decreased as a result of the incessant effort of the Korean government which adopted a policy of“drive out T.B.”as its foremost health policy. However, the proportion still remains relatively high com-pared with that of developed countries. This study attempts to find some means for guiding and educating college students who have T.B. in their health care by (1) first determining the effect if their self-concept and health beliefs on their behavior in regard to their disease and (2) then predicting the level of compliance of the new patients to the treatment suggested by the health specialist, before the commencement of the treatment. The subjects of this study consisted of 88 mald and female students at Y University who were diagnosed as minimal pulmonary T.B. patients and registered at the health clinic of Y University during the period between September 1, 1981 and March 31, 1953. Data were collected from them by means of questionnaire and interview. The instruments used for this study were (1) a part of Junghoon Choi's“Perceptual Orientation ,Scale”for measuring self-perception of patients and (2) Rosenberg's questionnaire for measuring patients' evaluation of self-esteem, and (3) an instrument for measuring patients' health beliefs which was developed by this researcher utilizing information available from references. The collected data were analyzed using descriptive statistics, chisquare test, Pearson correlation coefficient and t-test. The findings were as follows: 3. Test of hypotheses 1) Hypothesis 1: Patients with high self-concept will be high in health beliefs. For testing this hypothesis a calculation of Pearson correlation coefficient (r) between the patients' self-concept and their health beliefs was carried out. The result of this test was -. 0756 which was not significant at α=.05 and hence hypothesis 1 was not supported. 2) Hypothesis 2: Patients with a high self-concept will tend to be high in compliance with the suggested treatment. Again a Pearson correlaton coefficient was calculated between the two variaibles in the hypothesis. The calculated coefficient r was .1558 which was not significant at α=.05. Hence hypothesis 2 was rejected. 3) Hypothesis 3: Patients with high susceptibility will have a high compliance level. The correlation coefficient between the two variables was -.1975, which was significant at α=.05 but due to the negative sign hypothesis 3 could not be accepted. 4) Hypothesis 4: Patients who take their disease seriously will have a higher compliance level. The calculated correlation coefficient between the variables in this hypothesis was .1642 which was not significant at α=.05 and hence hypothesis 4 was rejected. 5) Hypothesis 5: Patients with a high sense of the benefit of treatment will have a high level of compliance. The computed correlation coefficient was .3129 which was significant at α=.05 and hence hypothesis 5 was acepted. 2. Findings from the correlation analysis were as follows: 1) Patients' susceptibility and their compliance to treatment was negatively correlated (r= -. 1975) which was significant at α= .05. This implies that as the patients' level of susceptibility increases their compliance level decreases. 2) Patients' susceptibility and their self-concept were negatively correlated (r= -. 1790) which was again singnificant at α=.05. The implication of this is that as the patients’self concept increases their susceptibility to disease decreases. 3) Patients' self-concept and their sense of benefit derieved from the treatment was positively correlated (r=.1970) which was significant at α=.05. That is, patients with a high self-concept perceived a great sense of benefit from the treatment. To summarize, patients who are low in susceptibility have a high level of compliance and self-concept.

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Influencing Factors of Korean Female Adolescent′s Clothing Behaviors: -Effects of Psychological Characteristics, Age and Residence- (청소년기 여학생의 의복행동에 대한 영향요인 연구;연령.지역 차이와 심리적 특성 변인들의 상대적 영향력)

  • 고애란;진병호;심정은
    • Journal of the Korean Society of Clothing and Textiles
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    • v.24 no.4
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    • pp.475-486
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    • 2000
  • The purpose of this research were to identify the differences in clothing behaviors and psychological characteristics ill relation to age and residence and to identify the relative effects of Korean female adolescent's psychological characteristics on the clothing behaviors. The instruments measuring 9 psychological characteristics-adolescent egocentrism, social and general self-efficacy, public and private self-consciousness, boredom susceptibility, optimal stimulation level, body attitudes-were adapted from previous studies. Clothing behavior measurements were developed based on the pilot study results or adapted from previous studies. The data. collected from 2284 nationwide sample of Korean female adolescents(early, middle, late) was analyzed by frequency, two-way ANOVA, and LISREL confirmatory factor analysis. Clothing behavior were factor analyzed and 6 factors were identified: dressing for others. conformity to peers, clothing interest, self-expression, psychological dependence and clothing exhibition. Effects of age were dominant in 6 out of 9 psychological characteristics and five clothing behavior factors except conformity to peers. Dominant main effect of residence was found oかy in boredom susceptibility. From the results of LISREL, adolescent egocentrism, public self-consciousness and sensation seeking tendency were found to be the most influential psychological characteristics of female adolescents'clothing behaviors.

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Development and Verification of Aircraft Controller and Transceiver Considering Lightning Induced Transient Susceptibility (유도낙뢰를 고려한 항공기용 제어기 및 송수신기 개발 및 검증)

  • Seo, Jung-Won;Park, Jae-Soo;Yoon, Chang-Bae;Hong, Su-Woon;Jung, Byoung-Koo;Shin, Young-Jun;Ha, Jung-Whan
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.29 no.8
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    • pp.583-593
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    • 2018
  • Lightning causes physical damage to aircraft, such as melting, burning and arcing, and magnetic field that occurs on the aircraft's outer body during the penetration of a lightning stroke causes voltage and current transients in the electronics and wiring within the aircraft. This effect will cause induced lightning strikes in the aircraft's internal airborne electronic systems, preventing safe flight. This paper introduces protection circuit design techniques, and the test results that meet the requirements for certification of criteria.

Progressive collapse analysis of buildings with concentric and eccentric braced frames

  • Larijan, Reza Jalali;Nasserabadi, Heydar Dashti;Aghayan, Iman
    • Structural Engineering and Mechanics
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    • v.61 no.6
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    • pp.755-763
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    • 2017
  • In this study, the susceptibility of different symmetric steel buildings with dual frame system to Progressive Collapse (PC) was assessed. Some ten-story dual frame systems with different type of braced frames (concentrically and eccentrically braced frames) were considered. In addition, numbers and locations of braced bays were investigated (two and three braced bays in exterior frames) to quantitatively find out its effect on PC resistance. An Alternate Path Method (APM) with a linear static analysis was carried out based on General Services Administration (GSA 2003) guidelines. Maximum Demand Capacity Ratio (DCR) for the elements (beams and columns) with highest DCRs ($DCR_{moment}$ and $DCR_{shear}$) is given in tables. The results showed that the three braced bays with concentric braced frames especially X-braced and inverted V-braced frame systems had a lower susceptibility and greater resistance to PC. Also, the results represented that the beams were more critical than columns against PC after the removal of column.

Null Glutathione S-transferase T1 and M1 Genotypes and Oral Cancer Susceptibility in China and India - a Meta-analysis

  • Peng, Jie;Liu, Hong-Zhou;Zhu, You-Jia
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.1
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    • pp.287-290
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    • 2014
  • Objective: Genetic variation is considered to strongly impact on detoxification of carcinogens and therefore is related to cancer risk. However, findings for the null genotypes of GSTT1 and GSTM1 have not always been consistent. Therefore the present meta-analysis was conducted. Methods: We accessed the reported study at different research areas and used various databases, including PubMed and Wanfang Med Onlion from 1990 to May 1st 2013. We calculated the odds ratio (OR), 95% confidence interval (CI) and P value for oral cancer by using Review Manager 5.1 and STATE 12. Results: We found that there was no increased oral cancer risk among subjects carrying GSTM1 and GSTT1 null genotype (OR=1.35, 95%CI=0.68-2.68, P=0.39) and (OR=1.41, 95%CI=0.72-2.77, P=0.31) in the Chinese population. In contrast, in studies in India a significant correlation between GSTM1 null genotype and oral cancer was observed (OR=1.59, 95%CI=1.20-2.11, P=0.001), but not in GSTT1 (OR=1.21, 95% CI=0.84-1.74, P=0.31). Conclusion: We discovered that GSTM1 deletion polymorphism had a significant effect on the susceptibility of oral cancer in the Indian population.