• 한국초전도ㆍ저온공학회논문지
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• 제7권2호
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• pp.21-26
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• 2005

Breakdown characteristics and survival probability of turn-to-turn models were investigated under ac and impulse voltage at 77K. For experiments, two test electrode models were fabricated: One is point contact model and the other is surface contact model. Both are made of copper wrapped by O.025mm thick polyimide film(Kapton). The experimental results were analyzed statistically using Weibull distribution in order to examine the wrapping number effects on voltage-time characteristics under ac voltage as well as under impulse voltage in LN$_{2}$. Also survival analysis were performed according to the Kaplan-Meier method. The breakdown voltages of surface contact model are lower than that of point contact model, because the contact area of surface contact model is wider than that of point contact model. Besides, the shape parameter of point contact model is a little bit larger than that of surface contact model. The time to breakdown t$_{50}$ is decreased as the applied voltage is increased, and the lifetime indices slightly are increased as the number of layers is increased. According to the increasing applied voltage and decreasing wrapping number, the survival probability is increased.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제42권
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• pp.29.1-29.7
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• 2020

Background: Microvascular reconstruction is the treatment of choice after oral cancer ablation surgery. There are few published studies of free flap survival among Korean populations. This study aimed to determine the survival rate after 121 consecutive cases of maxillofacial microvascular reconstruction and to analyze the complications associated with microsurgery. Methods: This study included consecutive patients who underwent microsurgical reconstruction with free flaps, from January 2006 through September 2019, performed by a single surgeon at the oral and maxillofacial surgery department of a tertiary medical center. A total of 121 cases were reviewed retrospectively. The flap survival rate, flap type, radiotherapy history, complications, and treatment results were analyzed. Results: Four different flap types were used for microvascular reconstruction: radial forearm (n = 65), fibula (n = 34), latissimus dorsi (n = 21), and serratus anterior muscle with rib bone free flap (n = 1). Total necrosis of the flap was found in four cases (two latissimus dorsi flaps and two fibular flaps). The free flap survival rate was 97.5%. Nineteen patients received radiotherapy before surgery, and none of them experienced flap failure. The mean operation time was 334 ± 83.1 min, and the mean ischemic time was 48.9 ± 12.7 min. Conclusions: The success rate was reliable and comparable with previous studies. The success rate was not affected by radiation therapy. Free flaps can be safely used even after radiation treatment.

• Korean Journal of Radiology
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• 제22권2호
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• pp.213-224
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• 2021

Objective: Clinical outcomes of patients who undergo transarterial chemoembolization (TACE) for single small hepatocellular carcinoma (HCC) are not consistent, and may differ based on certain imaging findings. This retrospective study was aimed at determining the efficacy of pre-TACE CT or MR imaging findings in predicting survival outcomes in patients with small HCC upon being treated with TACE. Besides, the study proposed to build a risk prediction model for these patients. Materials and Methods: Altogether, 750 patients with functionally good hepatic reserve who received TACE as the first-line treatment for single small HCC between 2004 and 2014 were included in the study. These patients were randomly assigned into training (n = 525) and validation (n = 225) sets. Results: According to the results of a multivariable Cox analysis, three pre-TACE imaging findings (tumor margin, tumor location, enhancement pattern) and two clinical factors (age, serum albumin level) were selected and scored to create predictive models for overall, local tumor progression (LTP)-free, and progression-free survival in the training set. The median overall survival time in the validation set were 137.5 months, 76.1 months, and 44.0 months for low-, intermediate-, and high-risk groups, respectively (p < 0.001). Time-dependent receiver operating characteristic curves of the predictive models for overall, LTP-free, and progression-free survival applied to the validation cohort showed acceptable areas under the curve values (0.734, 0.802, and 0.775 for overall survival; 0.738, 0.789, and 0.791 for LTP-free survival; and 0.671, 0.733, and 0.694 for progression-free survival at 3, 5, and 10 years, respectively). Conclusion: Pre-TACE CT or MR imaging findings could predict survival outcomes in patients with small HCC upon treatment with TACE. Our predictive models including three imaging predictors could be helpful in prognostication, identification, and selection of suitable candidates for TACE in patients with single small HCC.

• 동국한의학연구소논문집
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• 제7권2호
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• pp.149-154
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• 1999

생쥐의 전뇌허혈(全腦虛血) 모델에서 potassium cyanide 유발(誘發) 혼수시간(昏睡時間) 및 생존시간(生存時間), 감압성(減壓性) 무효소(無酵素) 부하시(負荷時) 생존시간(生存時間)을 측정(測定)하여 전뇌처혈시(全腦處血時) 뇌순환대사(腦循環代謝) 개선(改善) 효과(效果)를 관찰(觀察)하였다. KCN 유발(誘發) 혼수시간(昏睡時間)의 단축(短縮), 치사양(致死量)의 KCN에 대한 생존시간(生存時間)의 연장(延長), 감압(減壓)에 의한 무산소(無酸素) 부하시(負荷時) 생존시간(生存時間)의 연장(延長) 효과(效果)가 나타났다.

• 한국조경학회지
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• 제28권1호
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• pp.48-53
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• 2000

This study was carried out to investigate the growth characteristics and propagation methods of Prunus species as woody landscape plants. Both the flowering time and the survival rate of grafting were investigated. The results are obtained as follows: The total of flowering period of Prunus species in Kyonggi province area lasted for about 26 days. The flowering time of the species overlaps. These observations suggest that the possibility of interspecific pollination among Prunus species is very high in the kyonggi province area. The total number of flowers in the species in area was in as follows decreasing order : (1) Prunus yedoensis >Prunus pendula var. ascendens > Prunus subhitella > Prunus sesrulata for. fugenzo > Prunus leveillenana var. pendula. The number of carpels in each flower ranged from 0.3 for Prunus subhirtella to 1.8 for Prunus serulata for. fugenzo. In the caseof Prunus sesrulata for. fugenzo, the carpels appeared to be degenerated and thus losted their function. However, there exist two tyoes of Prunus subhirtella. While one type had normal carpel, the other had the degenerated one. The survival rate of grafting was investigated on May 19. Eighty there percent of the plants survived when the grafting was made in the greenhouse in January whereas the plants grafted in nursery in March survived less in that Prunus suhirtella showed 64%, Prunus leveilleana var. pendula 47%, Prunus sesrulata for. fugenzo 43%, Prunus yedoensis 62% and Prunus pendula var. ascendens 24%, respectively. Therefore, it suggested that high humidity and optimal temperature appeared to incase the survival rate of the grated plants. We therefore propose here that grafting should be done in the greenhouse that both humidity and temperature could be controlled to enhance the efficiency of grafting. This will enable as to perform grafting in winter as well.

• Journal of Korean Neurosurgical Society
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• 제48권3호
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• pp.251-258
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• 2010

Objective : Despite rapid evolution of shunt devices, the complication rates remain high. The most common causes are turning from obstruction, infection, and overdrainage into mainly underdrainage. We investigated the incidence of complications in a consecutive series of hydrocephalic patients. Methods : From January 2002 to December 2009, 111 patients underwent ventriculoperitoneal (VP) shunting at our hospital. We documented shunt failures and complications according to valve type, primary disease, and number of revisions. Results : Overall shunt survival time was 268 weeks. Mean survival time of gravity-assisted valve (GAV) was 222 weeks versus 286 weeks for other shunts. Survival time of programmable valves (264 weeks) was longer than that of pressure-controlled valves (186 weeks). The most common cause for shunt revision was underdrainage (13 valves). The revision rate due to underdrainage in patients with GAV (7 of 10 patients) was higher than that for other valve types. Of 7 patients requiring revision for GAV underdrainage, 6 patients were bedridden. The overall infection rate was 3.6%, which was lower than reported series. Seven patients demonstrating overdrainage had cranial defects when operations were performed (41%), and overdrainage was improved in 5 patients after cranioplasty. Conclusion : Although none of the differences was statistically significant, some of the observations were especially notable. If a candidate for VP shunting is bedridden, GAV may not be indicated because it could lead to underdrainage. Careful procedure and perioperative management can reduce infection rate. Cranioplasty performed prior to VP shunting may be beneficial.

• 한국조사연구학회지:조사연구
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• 제11권3호
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• pp.81-101
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• 2010

본 연구의 목적은 청소년의 최초 폭력 발생시점을 살펴보고, 최초 폭력 발생시점에 대하여 개인, 가족 및 학교체계변수들의 영향을 검증하는 것이다. 이를 위해 한국청소년패널조사에서 최초 폭력 발생시점을 회고적으로 응답한 자료에 비연속시간 생존분석(discrete-time survival analysis)을 적용하였다. 연구결과에 의하면, 최초의 폭력행동은 초등학교 시기에 발생할 확률은 매우 낮았으나, 중학교 1학년 시기부터 급증하여 고등학교 1학년이 되기까지 계속해서 증가하는 것으로 나타났다. 폭력행동의 최초 발생시점에 대한 개인체계요인 중에서는 성별, 자아존중감, 공격성이, 가족체계요인 중에서는 결손가정 여부와 부모의 학대요인이, 학교체계요인 중에서는 비행친구 수가 유의하게 나타났다. 본 연구의 결과를 바탕으로 최초 폭력 발생시점에 영향을 줄 수 있는 변수들에 초점을 맞추어 청소년의 폭력 발생을 예방하기 위한 적절한 대비책을 찾는 데 도움을 줄 것이다.

• Journal of Chest Surgery
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• 제28권3호
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• pp.280-286
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• 1995

In our hospital we have seen 38 cases of esophageal cancer from June 1984 until June 1994. They composed of 34[89% men and 4[11% women, their age distributed from 35 to 74, mean age was 57.55 7.43. Their symptoms were varied, dysphagia[97% , pyrosis[58% , chest pain[31% , weight loss[31% , anemia[8% , vomiting[5% , and hoarseness[1% . Surgical treatment was done with esophagectomy and upper GI reconstruction 35 cases, and palliative gastrostomy was 3 cases. There was no operative mortality, and operative morbidity was 8 cases of anastomotic leakage, 5 cases of wound infection, 5 cases of pleural effusion, hoarseness, pneumothorax, and lung abscess. Pathologic lesion distribution: upper thoracic esophagus 6 cases[16% , middle thoracic esophagus 17 cases[45% , and lower thoracic esophagus 15 cases[39% . There was no statistical difference of transhiatal esophagectomy and transthoracic esophagectomy in complications and hospitalization period in this study but we proved the superiority of gastric upper GI reconstruction rather than colon upper GI reconstruction in anastomotic leakage and hospitalization period. Cumulative survival rate was 76.2% in 1 year survival, 33.9% in 3 year survival, 25.4% in 5 year survival, 12.7% in 10 year survival. There was no relationship with the time of dysphagia with survival in this study.

• Asian Pacific Journal of Cancer Prevention
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• 제13권4호
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• pp.1579-1582
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• 2012

Objective: To assess differences in serum proteins in esophageal squamous cell carcinoma patients. Methods: 144 esophageal squamous cell carcinoma patients and 50 healthy volunteers were included in this study, with surface-enhanced laser desorption-ionization time-of-flight mass spectrometry and weak cation exchange magnetic beads. Follow-up allowed the relations between serum proteins and prognosis to be analyzed. Results: A total of 93 protein peaks were detected (molecular weight range: 1500-30000), 10 demonstrating statistically significant differences. There were no differences in protein peaks between 92 patients with a survival more than 2 years and 52 patients with survival less than 2 years. There were two significantly different protein peaks between 45 stage II patients with a survival more than 2 years and 14 stage II patients with survival less than 2 years. There was one significantly different protein peak between 22 stage III patients with a survival more than 2 years and 29 stage III patients with survival less than 2 years. Conclusion: Differences of serum proteins in esophageal squamous cell carcinoma are related to prognosis of patients. The protein fingerprint can be helpful for clinical diagnosis and treatment.

• Asian Pacific Journal of Cancer Prevention
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• 제16권8호
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• pp.3121-3123
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• 2015

The main objective of this paper was to assess the influence of educational level on the survival of uterine cervix cancer patients in our population. A total of 224 patients were registered in our registry, of which 178 had information on stage and different educational levels. The overall median survival (MS) was 23 months, with values of 18.5, 20.7 and 41.3 months for the illiterate, literate and qualified groups, respectively. In the illiterate patients, stage I was seen in 2.6% and stage IV in 11.8%, while in other 2 groups stage I was seen in 10% to 17% of patients at the time of diagnosis. The survival probability at around 50 months was around 42%, 30% and 26% (approximately) for qualified, literates and illiterates respectively [Log Rank (Mantel-Cox) showed p=0.023]. Emphasis on imparting education to females can be a part of comprehensive cancer control programme for improving the overall survival in patients with carcinoma of the uterine cervix in our population.