• Development and Reproduction
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• v.22 no.3
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• pp.245-252
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• 2018

To improve survival rates of vitrified pig oocytes, the treatment of cytoskeletal stabilizer on an appropriate time is one of the possible approaches. However, the exact treatment timing and effect of cytoskeletal stabilizer such as cytochalasin B (CB) is not well known during oocyte vitrification procedures. Thus, the present study was conducted to determine optimal treatment timing of CB during vitrification and warming procedures. In experiment 1, the survival rates of the postwarming pig oocytes were analyzed by fluorescein diacetate (FDA) assays with 4 classifications. In results, post-warming oocytes showed significantly (p<0.05) decreased number of alive oocytes (31.8% vs. 86.4%) compared to fresh control. In detail, the significant difference (p<0.05) was found only in strong fluorescence (18.2% vs. 70.5%) not in intermediate fluorescence groups (13.6% vs. 15.9%). In experiment 2, CB was treated before (CB-Vitri) and after (Vitri-CB) vitrification. In results, group of Vitri-CB showed significantly (p<0.05) higher (91.6%) survival rates compared to group of CB-Vitri (83.7%), significantly (p<0.05) and comparable with group of Vitri Control (88.7%) by morphological inspection. In FDA assay results, group of Vitri-CB showed significantly (p<0.05) higher (44.2%) survival rates compared to groups of CB-Vitri (36.7%) and Vitri Control (35.1%). In conclusion, the increased survival rates of post-warming pig oocyte treated with Vitri-CB method are firstly described here. The main finding of present study is that the CB treatment during recovery could be helpful to refresh the post-warming pig oocyte resulting its improved survival rates.

• Korean Journal of Cognitive Science
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• v.21 no.4
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• pp.697-723
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• 2010

Recent studies report that in terms of object memory, survival context has mnemonic advantage over other context conditions (e.g., Nairne et al, 2007). The present experiments explored whether this effect can also affect task-irreverent object location memory, and tested whether the context can change gender difference in object location memory. Participants were asked to rate the relevance of pictures presented at random locations (experiment 1) or words (experiment 2) under survival context or moving context. After rating the pictures or words, they answered recall test and location retrieval test. The results revealed higher accuracy in memory for objects encoded under survival context. Moreover, survival processing enhanced location memory, and the survival advantage in location memory emerged among woman.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.15 no.2
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• pp.760-766
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• 2014

This study was performed to determine the effect factors in the survival of cardiac arrest patients. This study involved 4,092 cardiac arrest patients of K province, who were transported by 119 during 2010. The data collection involved using 119 rescue daily reports, cardiopulmonary arrest patients emergency treatment detail reports and 119 paramedics survival data. In conclusion, 119 rescue's interventions in the patients with pre-hospital cardiac arrest have significantly increased survival rates. 119 rescue's interventions included early defibrillation, oxygen supply, airway open, and intravenous access affected significantly survival rate. Therefore there is need to increase 119 rescue's interventions performance to improve survival rate of cardiac arrest patients.

• Journal of Ginseng Research
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• v.25 no.2
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• pp.68-73
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• 2001

Studies were performed to determine the effect of red ginseng and white ginseng on jejunal crypt survival, endogenous spleen colony formation, and apoptosis of jejunal crypt cells in irradiated mice. The radioprotective effect of ginseng was compared with the effect of diethyldithocarbamate(D). Jejunal crypts were protected from irradiation by pretreatment of red ginseng (50 mg/kg B.W., I.P. at 36 and 12 hours before irradiation) and white ginseng (50 mg/kg B.W., I.P. at 36 and 12 hours before irradiation). Red ginseng administration before irradiation and both pretreatment and posttreatment (50 mg/kg B.W., I.P. at 30 minutes after irradiation) of white ginseng resulted in an increase of the formation of endogenous spleen colony. the frequency of radiation-induced apoptosis in intestinal crypt cells was also reduced by both pretreatment and posttreatment of red ginseng, and pretreatment of white ginseng. The radioprotective effect of DDC (1000 mg/kg B.W., I.P. at 30 minutes before irradiation) on jejunal crypt survival and apoptosis was similar to those of ginseng treatment. Treatment with DDC showed no significant modifying effects on formation of endogenous spleen colony. These results indicated that ginseng might be a useful radioprotector. Further studies are needed to characterize effective radioprotective components and mechanism of ginseng.

• Journal of Periodontal and Implant Science
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• v.38 no.sup2
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• pp.309-316
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• 2008

Purpose: The aim of this study was to determine the survival rates of implants placed in grafted maxillary sinuses and compare the results obtained with graft materials, implant surfaces and timing of implant placement. Materials and Methods: Between January 1996 and December 2005, 391 implants were placed in 161 patients who underwent sinus grafting treatment simultaneously or separately at Ewha Womans University Hospital. According to inclusion criteria, 272 implants were placed in 102 patients with 112 sinus grafts (30 females, 72 males), aged 26 to 88 years (mean age $49.0{\pm}9.7$). The follow-up period ranged from 12 to 134 months (mean F/U $47{\pm}32$). Survival rates were evaluated according to graft material, implant surface and timing of implant placement. The Kaplan-Meier procedure and the log rank (Mantel-Cox) test were used to estimate survival rates and test for equality of survival rates between different groups of patients. Results: Ten-year cumulative survival rate for implants placed in the grafted sinuses was 90.1%. The survival rates for autogenous bone, combination and bone substitutes were 94.6%, 85.9% and 100%, respectively (p > 0.05). According to implant surface, survival rates were 84.8% in machined group and 97.5% in rough group (p < 0.05). The survival rates were 92.9% in delayed group and 86.0% in simultaneous group (p > 0.05). Conclusion: Ten-year cumulative survival rate for implants placed in the grafted sinuses was 90.1%. Rough-surfaced implants have a higher survival rate than machined-surfaced implants when placed in grafted sinuses (p < 0.05).

• Communications for Statistical Applications and Methods
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• v.15 no.5
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• pp.727-735
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• 2008

Consider a clinical trial in which the main end-point is survival. Suppose after the start of the study an intermediate event occurs which may be influenced by a covariate(or treatment). In many clinical studies the occurrence of an intermediate event may change the survival distribution. This investigation develops two-stage model which, in the first stage, models the effect of covariate on the intermediate event and models the relationship between survival time and covariate as well as the intermediate event. In this paper, the two-stage model is presented in order to model intermediate event and a test based on this model is also provided. A numerical simulations are carried out to evaluate its overall significance level.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.44 no.6
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• pp.671-676
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• 2011

To determine the optimum light intensity for mass culture of the brackish-water cyclopoid copepod Paracyclopina nana, survival, growth, and productivity of the copepod were examined at several light intensities (0, 10, 100, 500, 1,000 lx). The survival rate of P. nana from nauplius to adult decreased with increasing light intensity. The highest survival rate was found under the dark condition, with 61.7% surviving; no significant difference was observed between 0 and 10 lx (51.7%) and the lowest survival rate was with 100 lx (26.7%). Survival rates at 500 and 1,000 lx were significantly lower in comparison with other conditions. The developmental period from nauplius to copepodid (5.8 days) and to adult (11.8 days) at 10 lx was significantly shorter than in the other treatments. Daily mean nauplius production of adult females over 7 days at 0, 10 and 100 lx was significantly higher than at 500 and 1,000 lx. In the 1,000 lx treatment, 99% of the adult females died on the $14^{th}$ day. The optimum light intensity for the mass culture of P. nana could be 10 lx, which had no adverse effects on survival, development, or reproduction.

• Journal of Gastric Cancer
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• v.16 no.2
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• pp.78-84
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• 2016

Purpose: The aim of this study was to determine whether surgical resection of the primary tumor contributes to survival in patients with metastatic gastric cancer. Materials and Methods: A total of 288 patients with metastatic gastric cancer from the Akdeniz University, Antalya Training and Research Hospital, and the Meram University of Konya database were retrospectively analyzed. The effect of primary tumor resection on survival of patients with metastatic gastric cancer was investigated using the log-rank test. Kaplan-Meier survival estimates were calculated. Multivariate analysis was performed using Cox proportional hazards regression modeling. Results: The median overall survival was 12.0 months (95% confidence intewrval [CI], 10.4~13.6 months) and 7.8 months (95% CI, 5.5~10.0 months) for patients with and without primary tumor resection, respectively (P<0.001). The median progression-free survival was 8.3 months (95% CI, 7.1~9.5 months) and 6.2 months (95% CI, 5.8~6.7 months) for patients with and without primary tumor resection, respectively (P=0.002). Conclusions: Non-curative gastrectomy in patients with metastatic gastric cancer might increase their survival rate regardless of the occurrence of life-threatening tumor-related complications.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.9
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• pp.4387-4391
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• 2012

Background: Lung carcinoma is the leading cause of cancer mortality worldwide. Although the 5-year survival rate nearly tripled from 5-15% over the last 25 years, the estimated number of deaths still exceeds 1.3 million annually. The overall 5-year survival of lung cancer is only 10% in Europe and 15% in the United States. The aim of the current study was to determine the long-term survival and the effect of certain prognostic factors on survival of patients with lung cancer in Yazd city, Iran. Methods: In this cross-sectional descriptive study, we retrospectively reviewed hospital records and follow-up data of 148 patients with histological proven lung cancer using the cancer data registered between 1998 and 2005 in the pathology department of Shahid Sadoughi educational hospital, Yazd, Iran. Data were extracted from patient documents that included sex, age, clinical manifestations, histopathological report of the tumor and type of treatment given. Results: Overall survival time in all patients was 8.5 months after diagnosis and there was no significant difference in survival according to sex (p=0.958). Histological analysis revealed that squamous cell carcinoma was the most common histologic type (35%). Kaplan-Meier statistical methods estimated the average survival time for SCC to be better (22.6 months) in comparison with the other types of histology (all of them below 10 months). There was a trend towards significance between type of histology and duration of survival (p=0.08). Conclusion: It is reasonable to expect that early lung cancer detection, and appropriated treatment, may improve surgical morbidity and mortality. Low survival of lung cancer in our center patients show our shortages in screening programs for early diagnosis. Designing studies with larger sample size that take some other variables like staging of patients is now necessary.

• Restorative Dentistry and Endodontics
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• v.46 no.2
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• pp.29.1-29.11
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• 2021

Objectives: This study was conducted to compare the post-fracture survival rate of endodontically treated molar endodontically treated teeth (molar ETT) restored with resin composites or crowns and to identify potential risk factors, using a retrospective cohort design. Materials and Methods: Dental records of molar ETT with crowns or composite restorations (recall period, 2015-2019) were collected based on inclusion and exclusion criteria. The incidence of unrestorable fractures was identified, and molar ETT were classified according to survival. Information on potential risk factors was collected. Survival rates and potential risk factors were analyzed using the Kaplan-Meier log-rank test and Cox regression model. Results: The overall survival rate of molar ETT was 87% (mean recall period, 31.73 ± 17.56 months). The survival rates of molar ETT restored with composites and crowns were 81.6% and 92.7%, reflecting a significant difference (p < 0.05). However, ETT restored with composites showed a 100% survival rate if only 1 surface was lost, which was comparable to the survival rate of ETT with crowns. The survival rates of ETT with composites and crowns were significantly different (97.6% vs. 83.7%) in the short-term (12-24 months), but not in the long-term (> 24 months) (87.8% vs. 79.5%). Conclusions: The survival rate from fracture was higher for molar ETT restored with crowns was higher than for ETT restored with composites, especially in the first 2 years after restoration. Molar ETT with limited tooth structure loss only on the occlusal surface could be successfully restored with composite restorations.