• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2013.10a
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• pp.507-509
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• 2013

This paper covers the individual with mild autistic disorder complementary and alternative communication Support program by using Android. The complementary and alternative communication is the communicative system to help handicapped people who have problems with colloquial and non-colloquial communication. In this research, we will introduce the communication manner of autistic disorder, the method of how to measure the language disabled people's selection and frequency of the words, and the basic training method of Autism people's communication ways. In this paper, we developed complementary and alternative communication system which used language representative method to encourage language disabled people to study on communication in effective way. We utilized 'TTS technology' to enable handicapped people delivering their mind with the voice; moreover, by listening their voice by themselves, we accelerated their studies on communications. In addition, by offering 'Painting function', we promoted handicapped people to deliver their purpose widely and efficiently. Also, we built the smart system in 'Painting function' to collect frequency and educated degree data from the users by using this function, we can analyze the percentage of conscious and unconscious communication way of Autism cases to help them.

• Speech Sciences
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• v.1
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• pp.153-200
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• 1997

In languages such as Japanese, it is very common to observe that short peripheral vowel are completely voiceless when surrounded by voiceless consonants. This phenomenon has been known as Montreal French, Shanghai Chinese, Greek, and Korean. Traditionally this phenomenon has been described as a phonological rule that either categorically deletes the vowel or changes the [+voice] feature of the vowel to [-voice]. This analysis was supported by Sawashima (1971) and Hirose (1971)'s observation that there are two distinct EMG patterns for voiced and devoiced vowel in Japanese. Close examination of the phonetic evidence based on acoustic data, however, shows that these phonological characterizations are not tenable (Jun & Beckman 1993, 1994). In this paper, we examined the vowel devoicing phenomenon in Korean using data from ENG fiberscopic and acoustic recorders of 100 sentences produced by one Korean speaker. The results show that there is variability in the 'degree of devoicing' in both acoustic and EMG signals, and in the patterns of glottal closing and opening across different devoiced tokens. There seems to be no categorical difference between devoiced and voiced tokens, for either EMG activity events or glottal patterns. All of these observations support the notion that vowel devoicing in Korean can not be described as the result of the application of a phonological rule. Rather, devoicing seems to be a highly variable 'phonetic' process, a more or less subtle variation in the specification of such phonetic metrics as degree and timing of glottal opening, or of associated subglottal pressure or intra-oral airflow associated with concurrent tone and stricture specifications. Some of token-pair comparisons are amenable to an explanation in terms of gestural overlap and undershoot. However, the effect of gestural timing on vocal fold state seems to be a highly nonlinear function of the interaction among specifications for the relative timing of glottal adduction and abduction gestures, of the amplitudes of the overlapped gestures, of aerodynamic conditions created by concurrent oral tonal gestures, and so on. In summary, to understand devoicing, it will be necessary to examine its effect on phonetic representation of events in many parts of the vocal tracts, and at many stages of the speech chain between the motor intent and the acoustic signal that reaches the hearer's ear.

• Language and Information
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• v.19 no.2
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• pp.127-153
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• 2015

Negative expressions have their semantic function of classical negation as a pure reverser of truth-values. They also have various kin and foes of their pragmatic functions such as association of bad feelings (Russell 1948), emphasis/attenuation by negative polarity items, sarcasm, and metalinguistic negation (MN). This paper explores how MN and descriptive negation (DN) differ and whether the difference creates pragmatic ambiguity (Horn 1987) or reflects merely contextual variations of one logical negation (Carston 1996). To test the debate, this paper treats certain degree modifiers licensed exclusively by MN as in Mia-ka POTHONG/Yekan yeppu-n key an-i-a [external neg] (vs. modifier NPIs like cenhye 'at all', licensed only by DN) and contrasts them with bad utterances of the MN modifiers in [short form neg] sentences (not for MN) such as Mia-ka POTHONG an yeppu-e. The ERP results of the well-formed vs. ill-formed conditions evoked the N400 at Cz in written stimuli and the N400 near the center on both hemispheres in spoken stimuli. The results suggest that the anomalies are meaning-related and tend to support the pragmatic ambiguity.

• Journal of Electrical Engineering and Technology
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• v.12 no.6
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• pp.2118-2126
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• 2017

The large-scale power system blackouts have indicated that conventional protection relays that based on local signals cannot fit for modern power grids with complicated setting or heavily loaded-flow transfer. In order to accurately detect various faulted lines and improve the fault-tolerance of wide-area protection, a novel multi-section weighed fault matching and detecting algorithm is proposed. The real protection vector (RPV) and expected section protection vectors (ESPVs) for five fault sections are constructed respectively. The function of multi-section weighed fault matching is established to calculate the section fault matching degrees between RPV and five ESPVs. Then the fault degree of protected line based on five section fault degrees can be obtained. Two fault detecting criterions are given to support the higher accuracy rate of detecting fault. With the enumerating method, the simulation tests illustrate the correctness and fault-tolerance of proposed algorithm. It can reach the target of 100% accuracy rate under 5 bits error of wide-area protections. The influence factors of fault-tolerance are analyzed, which include the choosing of wide-area protections, as well as the topological structures of power grid and fault threshold.

• Phonetics and Speech Sciences
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• v.5 no.3
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• pp.83-93
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• 2013

Vocal hygiene education is an indirect training approach to improve vocal function by educating all facets of optimal vocal health. Satisfaction levels of participants might be an important component of this indirect therapy for voice disorders. The authors aimed to investigate the satisfaction levels of vocal hygiene education in 51 patients with voice problems. We classified voice disorders of the participants according to three etiological categories (subgroups): organic, neurogenic, and functional. The survey consisted of three parts: 1) a condition of vocal hygiene education, 2) a degree of satisfaction of the present education, and 3) a request for future education. Participants responded to each item of the survey using a five-point Likert scale of 1 to 5 (1 being not at all and 5 being extremely). They also wrote down personal comments of improvement. Participants scored the vocal hygiene education offered by the speech-language pathologists between '3' and '4'. Specifically, the participants were highly satisfied with the specific and comprehensible explanation/instruction given by their speech-language pathologists. However, they were less satisfied with the tuition fee for the therapy sessions. Vocal hygiene education is offered individually to people in a clinical setting. Our results support the notion that vocal hygiene education can be an integral aspect of the treatment of voice problems in most cases.

• Biomolecules & Therapeutics
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• v.26 no.1
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• pp.10-18
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• 2018

Tumors are dynamic metabolic systems which highly augmented metabolic fluxes and nutrient needs to support cellular proliferation and physiological function. For many years, a central hallmark of tumor metabolism has emphasized a uniformly elevated aerobic glycolysis as a critical feature of tumorigenecity. This led to extensive efforts of targeting glycolysis in human cancers. However, clinical attempts to target glycolysis and glucose metabolism have proven to be challenging. Recent advancements revealing a high degree of metabolic heterogeneity and plasticity embedded among various human cancers may paint a new picture of metabolic targeting for cancer therapies with a renewed interest in glucose metabolism. In this review, we will discuss diverse oncogenic and molecular alterations that drive distinct and heterogeneous glucose metabolism in cancers. We will also discuss a new perspective on how aberrantly altered glycolysis in response to oncogenic signaling is further influenced and remodeled by dynamic metabolic interaction with surrounding tumor-associated stromal cells.

• Journal of Institute of Control, Robotics and Systems
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• v.4 no.6
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• pp.713-721
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• 1998

In this paper a new modeling and an optimal pole-placement control for the suspension system of Macpherson type are investigated. The rotational motion of the unsprung mass is emphasized in the new modeling. The two generalized coordinates selected in the new model are the vortical displacement of sprung mass and the angular displacement of control arm. Both variables are measured from their static equilibrium points. It is shown that the conventional model is a special case of the new model since the transfer function of the new model coincides with that of the conventional one if the lower support point of the shock absorber is located at the mass center of the unsprung mass. It is also shown that the resonance frequencies of the new model agree better with experimental results. Therefore, the new model is more general in the sense that it Provides an extra degree of freedom in determining the plant model for control system design. An optimal pole-placement control which combines LQ control and pole-placement technique is applied to the new model. Simulations are provided.

• Clinical and Experimental Pediatrics
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• v.53 no.3
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• pp.273-285
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• 2010

Completion of the human genome project has allowed a deeper understanding of molecular pathophysiology and has provided invaluable genomic information for the diagnosis of genetic disorders. Advent of new technologies has lead to an explosion in genetic testing. However, this overwhelming stream of genetic information often misleads physicians and patients into a misguided faith in the power of genetic testing. Moreover, genetic testing raises a number of ethical, legal, and social issues. Diagnostic genetic tests can be divided into three primary but overlapping categories: cytogenetic studies (including routine karyotyping, high-resolution karyotyping, and fluorescent in situ hybridization studies), biochemical tests, and DNA-based diagnostic tests. DNA-based testing has grown rapidly over the past decade and includes preandpostnatal testing for the diagnosis of genetic diseases, testing for carriers of genetic diseases, genetic testing for susceptibility to common non-genetic diseases, and screening for common genetic diseases in a particular population. Theoretically, once a gene's structure, function, and association with a disease are well established, the clinical application of genetic testing should be feasible. However, for routine applications in a clinical setting, such tests must satisfy a number of criteria. These criteria include an acceptable degree of clinical and analytical validity, support of a quality assurance program, possibility of modifying the course of the diagnosed disease with treatment, inclusion of pre-and postnatal genetic counseling, and determination of whether the proposed test satisfies cost-benefit criteria and should replace or complement traditional tests. In the near future, the application of genetic testing to common diseases is expected to expand and will likely be extended to include individual pharmacogenetic assessments.

• Proceedings of the Membrane Society of Korea Conference
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• 2005.11a
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• pp.133-147
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• 2005

In order to investigate applicability for 2,2,2-trifluoroethyl methacrylate (TFEMA) produced by esterification of 2,2,2-trifluoroethanol(TFEA) and methacrylic acid(MA) using pervaporation membrane, poly(vinyl alcohol) (PVA) composite membranes were prepared with glutaraldehyde(GA) onto porous polyethersulfone(PES) support. The degree of crosslinking and thickness of PVA coating layer were analyzed by swelling test and SEM(scanning electron microscopy), respectively. Pervaporation test was done with two feed mixures; TFEA/water, MA/water. The pervaporation data were obtained as a function of content of crosslinking agent, feed composition, and operating temperature, respectively. In case of TFEA-water(90/10 wt%) feed mixture at $80^{\circ}C$, the optimized membrane showed the high permeation flux of 1.5 $kg/m^2hr$ and separation factor of 320. In case of MA-water(90/10 wt%) feed mixture, the membranealso showed high permeation flux of 2.3 $kg/m^2hr$ and separation factor of 740 in same conditions.

• Journal of the Korean Association of Geographic Information Studies
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• v.8 no.2
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• pp.103-116
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• 2005

Although there have been many researches to construct a database of water distribution networks using GIS, most of them were not linked with an model for the analysis of pipe networks because it is difficult to make spatial data about complex water distribution networks for building a detail model. Therefore, it is necessary to develop the method based on GIS to build geographical data for design of water distribution pipeline systems. In this study, an innovated design support technique using GIS is proposed for a hydraulic analysis model of water distribution networks. With the function of spatial analysis in GIS system, the results from a pipe network model are used to analyze the suitability of the location of pipeline network, the spatial suitability comprised the analysis of the degree of pipe age, the altitude distribution of water pressure, and the water supply system for the customer.