• Title/Summary/Keyword: sup property

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Design of the Vector-Scalar Quantizer of LSP Parameters for Wideband Speech Coder (광대역 음성부호화기를 위한 백터-스칼라 LSP 파라미터 양자화기 설계)

  • 신재현;이인성;지덕구;윤병식;최송인
    • Journal of the Institute of Electronics Engineers of Korea SP
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    • v.40 no.4
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    • pp.286-291
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    • 2003
  • In this Paper, we designed an LSP(Line Spectral Pairs) parameter quantizer with cascaded structure of vector quantizer and scalar quantizer for the wideband speech coder. We have chosen the 16th-order of the LP coefficients. These coefficients are then transformed into the LSP parameters which have the excellent properties for quantization and easy stability checking condition of synthesis filter. In the first stage of quantization, input LSP parameters are split-vector-quantized using two 8-th order codebooks. In the second stage, the components of residual vector are individually quantized by the scalar quantizer utilizing the ordering property of LSP parameters. The designed adaptive VQ-SQ quantizer using 35 bits/frame shows the wideband transparency that the average spectral distortion should be less than 1.6 ㏈ and less than 4% of the frames should have SD above 3 ㏈. The simulation results show that the designed quantizer provides a 2-3 bits/frame saving over the typical vector-scalar quantizer.

In vitro and in vivo pharmacokinetic characterization of LMT-28 as a novel small molecular interleukin-6 inhibitor

  • Ahn, Sung-Hoon;Heo, Tae-Hwe;Jun, Hyun-Sik;Choi, Yongseok
    • Asian-Australasian Journal of Animal Sciences
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    • v.33 no.4
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    • pp.670-677
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    • 2020
  • Objective: Interleukin-6 (IL-6) is a T cell-derived B cell stimulating factor which plays an important role in inflammatory diseases. In this study, the pharmacokinetic properties of LMT-28 including physicochemical property, in vitro liver microsomal stability and an in vivo pharmacokinetic study using BALB/c mice were characterized. Methods: LMT-28 has been synthesized and is being developed as a novel therapeutic IL-6 inhibitor. The physicochemical properties and in vitro pharmacokinetic profiles such as liver microsomal stability and Madin-Darby canine kidney (MDCK) cell permeability assay were examined. For in vivo pharmacokinetic studies, pharmacokinetic parameters using BALB/c mice were calculated. Results: The logarithm of the partition coefficient value (LogP; 3.65) and the apparent permeability coefficient values (Papp; 9.7×10-6 cm/s) showed that LMT-28 possesses a moderate-high cell permeability property across MDCK cell monolayers. The plasma protein binding rate of LMT-28 was 92.4% and mostly bound to serum albumin. The metabolic half-life (t1/2) values of LMT-28 were 15.3 min for rat and 21.9 min for human at the concentration 1 μM. The area under the plasma drug concentration-time curve and Cmax after oral administration (5 mg/kg) of LMT-28 were 302±209 h·ng/mL and 137±100 ng/mL, respectively. Conclusion: These data suggest that LMT-28 may have good physicochemical and pharmacokinetic properties and may be a novel oral drug candidate as the first synthetic IL-6 inhibitor to ameliorate mammalian inflammation.

Liquid Metal Enabled Thermo-Responsive Poly(N-isopropylacrylamide)Hydrogel for Reversible Electrical Switch (액체금속이 첨가된 온도 감응성 poly(N-isopropylacrylamide) 하이드로젤의 전기적 특성 변화 고찰)

  • Lim, Taehwan;Lee, Sohee;Yeo, Sang Young
    • Textile Coloration and Finishing
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    • v.34 no.3
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    • pp.207-216
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    • 2022
  • Hydrogels have gained considerable attention in various fields due to their easily transformative ability by different stimulation. In addition, metal-based conductive additives can enable the hydrogels to be conductive with dimension change. Although the development of the additives offered enhanced electrical properties to the hydrogels, correspondingly enhanced mechanical properties may limit the volume and electrical properties switching after stimulation. Here we prepared poly(N-isopropylacrylamide) (PNIPAM) thermo-responsive hydrogel that has a 32℃ of low critical solution temperature and added liquid metal particles (LMPs) as conductive additives, possessing soft and stretchable benefits. The LMPs enabled PNIPAM (PNIPAM/LMPs) hydrogels to be constricted over 32℃ with a high volume switching ratio of 15.2 when deswelled. Once the LMPs are spontaneously oxidized in hydrogel culture, the LMPs can release gallium ions into the hydrogel nature. The released gallium ions and oxidized LMPs enhanced the modulus of the PNIPAM/LMPs hydrogel, triggering high mechanical stability during repeated swelling/deswelling behavior. Lastly, highly constricted PNIPAM/LMPs hydrogel provided a 5x106 of electrical switching after deswelling, and the switching ratio was closely maintained after repeated swelling/deswelling transformation. This study opens up opportunities for hydrogel use requiring thermo-responsive and high electrical switching fields.

The Adhesion Property of Fish Glue (어교(魚膠)의 접착특성)

  • Lee, Young-Kyu;Hwang, Hyeon-Deuk;Kim, Hyun-Joong
    • Journal of the Korean Wood Science and Technology
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    • v.32 no.5
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    • pp.59-65
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    • 2004
  • The present study aims to optimise the process parameters of fish glue and adhesion property through room temperature in terms of curing time and opened assembly time for attaining best adhesion strength to wood (Yellow birch, B. alleghaniensis). The uncured and cured fish glue have been characterised by TGA, DSC, FT-JR. It is observed that with increasing curing time up to 48 H, tensile lap shear strength of adhesive joint of fish glue to wood increases and decreases after 48 H. At 15 min. opened assembly time, lap shear strength increases up to 4833 kgf/cm2 and decreases after 15 min.

A study on the manufacturing of durable and long afterglow phosphorescent paints added with rare earths for night visibility of pavement (야간 시인성 확보를 위한 희토류 첨가 고내구성 장잔광 축광도료 제조에 관한 연구)

  • Eunseok Woo;Yunseok Noh;Jinho Lee;Yong-Wook Choi;JongGee Kim
    • Journal of the Korean institute of surface engineering
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    • v.56 no.2
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    • pp.152-159
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    • 2023
  • The night visibility of pavement is being considered as a global issue in the field of traffic safety. Although the spreading glass beads on the lane paints has been mainly used to secure night-visibility by utilizing the effect of retroreflection, obvious shortcoming of this method is that retroflection does not occur in the range where the headlights do not reach the glass beads. The use of functional paints including phosphorescent constituents could be a solution for overcoming fore-mentioned problem. SrAl2O4 based chemicals have not only good phosphorescent property, but also are chemically stable compared to existing ZnS based materials. However, this chemicals also need the improvement due to slightly reduced luminous effect in time. Herein, we developed novel paints showing enhanced phosphorescent properties by putting rare earth elements such as Eu, Dy and Y into SrAl2O4. These prepared phosphorescent pigments have displayed improved properties in terms of durability and long afterglow. For instance, the property of afterglow has been persisted after 5 hours with luminace of 20.6 mcd/m2.

Design of Small-Area MTP Memory Based on a BCD Process (BCD 공정 기반 저면적 MTP 설계)

  • Soonwoo Kwon;Li Longhua;Dohoon Kim;Panbong Ha;Younghee Kim
    • Journal of IKEEE
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    • v.28 no.1
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    • pp.78-89
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    • 2024
  • PMIC chips based on a BCD process used in automotive semiconductors require multi-time programmable (MTP) intellectual property (IP) that does not require additional masks to trim analog circuits. In this paper, MTP cell size was reduced by about 18.4% by using MTP cells using PMOS capacitors (PCAPs) instead of NMOS capacitors (NCAPs) in MTP cells, which are single poly EEPROM cells with two transistors and one MOS capacitor for small-area MTP IP design. In addition, from the perspective of MTP IP circuit design, the two-stage voltage shifter circuit is applied to the CG drive circuit and TG drive circuit of MTP IP design, and in order to reduce the area of the DC-DC converter circuit, the VPP (=7.75V), VNN (=-7.75V) and VNNL (=-2.5V) charge pump circuits using the charge pumping method are placed separately for each charge pump.

A study on the Frequency Dependence of Dynamic Pyroelectric Properties for $Pb_{l-x}La_{x}Ti_{l-x/4}O_3$ (x=0.1) (PLT(10)) Ferroelectric Thin Film ($Pb_{l-x}La_{x}Ti_{l-x/4}O_3$ (x=0.1) (PLT(10)) 강유전체 박막에서 동적 초전특성의 주파수의존성에 관한 연구)

  • 차대은;장동훈;강성준;윤영섭
    • Journal of the Institute of Electronics Engineers of Korea SD
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    • v.39 no.12
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    • pp.1008-1015
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    • 2002
  • The fabricated La-modified lead titanate (PLT) thin film without poling treatment was investigated for modulation frequency dependence of pyroelectric properties by the dynamic method. $Pb_{l-x}La_{x}Ti_{l-x/4}O_3$(x=0.1) (PLT(10)) thin film haying 10 mol% La content was deposited on a Pt/$TiO_{x}$/$SiO_2$/Si substrate by sol-gel method. The PLT(10) thin film exhibits a relatively excellent dielectric property. The pyroelectric coefficient (p) of the PLT(10) thin film is 6.6 x $10^{-9}C$$textrm{cm}^2$$.$K without frequency dependence. The figure of merits for the voltage responsivity and specific detectivity are 1.03 x $10^{-11}C$.cm/J and 1.46 x $10^{-10}C$.cm/J, respectively The PLT(10) thin film has voltage responsivity (RV) of 5.IS V/W at 8 Hz. Noise equivalent power (NEP) and specific detectivity ($D^{*}$) of the PLT(10) thin film are 9.93 x $10^{-8}$W/$Hz^{1/2}$ and 1.81 x $10^{6}$cm.$Hz^{1/2}$/W at the same frequency of 100 Hz,, respectively The results means that PLT thin film having 10 mol% La content is suitable for the sensing materials of pyroelectric IR sensors.

A Method for Scalar Multiplication on Elliptic Curves against Differential Power Analysis using Efficient Key-Randomization (효율적인 키-난수화를 사용한 차분 전력 분석 공격에 대응하는 타원곡선 위의 스칼라 곱셈 방법)

  • Jung, Seok Won
    • The Journal of the Korea Contents Association
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    • v.20 no.1
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    • pp.356-363
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    • 2020
  • As a becoming era of Internet-of-Things, various devices are connected via wire or wirless networks. Although every day life is more convenient, security problems are also increasing such as privacy, information leak, denial of services. Since ECC, a kind of public key cryptosystem, has a smaller key size compared to RSA, it is widely used for environmentally constrained devices. The key of ECC in constrained devices can be exposed to power analysis attacks during scalar multiplication operation. In this paper, a key-randomization method is suggested for scalar multiplication on SECG parameters. It is against differential power analysis and has operational efficiency. In order to increase of operational efficiency, the proposed method uses the property 2lP=∓cP where the constant c is small compared to the order n of SECG parameters and n=2l±c. The number of operation for the Coron's key-randomization scalar multiplication algorithm is 21, but the number of operation for the proposed method in this paper is (3/2)l. It has efficiency about 25% compared to the Coron's method using full random numbers.

Thermal stabilizing effect of Yb3+ Er3+ codoping into TiO2 powder prepared by sol-gel method and its upconversion characteristic (Yb3+ Er3+ ions 동시도핑에 의한 TiO2 분말의 열적 안정성 증가효과와 upconversion 특성 연구)

  • Eun, Jong-Won;Oh, Dong-Keun;Kim, Kwang-Jin;Hong, Tae-Ui;Jeong, Seong-Min;Choi, Bong-Geun;Shim, Kwang-Bo
    • Journal of the Korean Crystal Growth and Crystal Technology
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    • v.20 no.4
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    • pp.173-177
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    • 2010
  • Thermal stabilizing effect of $Yb^{3+},\;Er^{3+}$ codoping into $TiO_2$ powder prepared by sol-gel method and its upconversion characteristics were analyzed. The effect of $TiO_2:Yb^{3+},\;Er^{3+}$ ions on crystallinity and phase transition was studied by X-ray diffraction (XRD). The change of band-gap energy induced from Yb and Er codoping was analyzed by UV-Vis. The band-gap energy of $TiO_2$ have been slightly narrowed by $Yb^{3+},\;Er^{3+}$ codoping, which indicated that the $Yb^{3+},\;Er^{3+}$ ions can enhance the photo-catalytic property of $TiO_2$. green and red up-conversions of $Yb^{3+}$ and $Er^{3+}$ co-doped $Y_2O_3:Yb^{3+},\;Er^{3+}$ phosphor were analyzed by PL equipped with 980 nm laser.

Synthesis and Property Evaluation of Bio-adhesives Using Peach Gum(桃膠) (도교(桃膠)를 이용한 바이오 접착제의 합성 및 물성 평가)

  • Park, Min-Seon;Oh, Seung-Jun;Wi, Koang-Chul
    • Journal of Conservation Science
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    • v.37 no.3
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    • pp.282-288
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    • 2021
  • This basic research was conducted to support the development of woodcraft bio-adhesives using peach gum, which is the resin produced by peach trees. The synthesis conditions of these adhesives were optimized by performing 144 experiments. The application potential of peach gum adhesives was explored by comparing their properties with those of three natural adhesives and four synthetic adhesives. The best adhesive strength was obtained by dissolving the resin in 80 mL of distilled water containing 1.5 g NaOH, 1.65 g H2O2 ( pH 8.0-9.0), 0.5 g NaClO, and 0.5 g H2BO2. The adhesive strength, which showed minimal changes and excellent reversibility, was 125.39 kgf/cm2. Ultraviolet radiation-mediated deterioration in strength in the absence of total aerobic bacteria was negligible (△E*ab = 2.75). These data confirm the potential value of peach gum-based bio-adhesives for woodcraft as well as their utility as alternatives for natural and synthetic adhesives used for the manufacture and restoration of handicrafts and preservation of cultural assets.