• 대한수의학회지
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• 제1권1호
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• pp.73-74
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• 1961

This concerns the summary report of a series of studies on Metastrongylosis hitherto published by the writer. The life cycle of swine lungworm was first elucidated by Hobmaier in 1929. Since then subsequent studies conducted by many workers have revealed that some species of earthworms act as specific intermediate hosts of swine lungworm. The writer observed that three species of earthworms, Helodrilus foetidus, Allolobophora caliginosa and Pheretima, serve as intermediate hosts of swine lungworm in Korea. The present summary consists of the results of survey on the distribution of infectious lungworm larvae and the studies on the developmental growth of lungworm larvae in the intermediate and terminal hosts.

• 기술사
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• 제32권1호
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• pp.74-77
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• 1999

• 대한간호
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• 제11권3호통권59호
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• pp.62-63
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• 1972

• 대한간호
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• 제19권4호통권107호
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• pp.82-85
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• 1980

• ESCO지
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• 통권2호
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• pp.64-67
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• 2000

• 화약ㆍ발파
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• 제17권1호
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• pp.56-59
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• 1999

• 대한방사선협회지
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• 제27권2호
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• pp.286-290
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• 2001

• ESCO지
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• 통권3호
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• pp.62-64
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• 2000

• ESCO지
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• 통권4호
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• pp.70-73
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• 2000

• 한국환경보건학회지
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• 제37권5호
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• pp.358-368
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• 2011

Objectives: In order to evaluate the association between occupational exposure to chloroethylene (TCE) and risk of non-Hodgkin lymphoma (NHL), we conducted a meta-analysis of retrospective cohort studies and casecontrol studies and attempted to summarize the evidence of the association from molecular-epidemiological studies and experiments with human cells. Methods: In the meta-analysis, we restricted the analysis to those studies with data for chlorinated solvents, degreasers, or TCE. Studies involving dry cleaners or launderers were excluded from the analysis because use of TCE as a dry cleaning fluid has been rare since the 1960s. The data were combined using a random-effects model to estimate the summary risks (OR and RR) and 95% confidence intervals (CIs). Molecular evidence of the effect of TCE on human immune system were also reviewed and summarized. Results: Occupational exposure to TCE was strongly associated with NHL among cohort studies (number of studies=13, summary RR=1.33, 95% CI=1.04-1.70) whereas the association was not statistically significant among case-control studies (number of studies=15, summary OR=1.10, 0.98-1.23). When exposure level was considered, it became statistically significant for the highest exposure level (number of studies=5, summary OR=1.70, 1.25-2.32). Molecular evidences showed that TCE exposure in human or cultured human cells may cause a significant decrease immune cell subsets and changes in hormone levels related to immune response. Conclusions: Our results from meta-analysis and additional molecular evidence suggest that occupational exposure to TCE may cause NHL. However, unmeasured potential confounding and unclear dose-response relationships warrant further study on the role of TCE exposure in NHL carcinogenesis.