• Journal of East-West Nursing Research
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• v.20 no.2
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• pp.93-102
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• 2014

Purpose: This study aimed to investigate the characteristics of patients attempting suicide and to analyze treatment determination factors for patients with mental illness who go to an emergency center for treatment. Methods: Data collected from 117 suicide attempters who visited Busan Regional Emergency Medical Center were analyzed using frequency, percentage, ${\chi}^2$-test with SPSS/WIN 15.0. Results: Only 31 cases consulted with the psychiatric department; the other attempters' refused to consult (26.5%). Among the 31 attempters who consulted, 23 cases (74.2%) were suffering from depression. The most common reason (38.6%) suicidal attempters gave to refuse psychiatric treatment was "I'm not mad. I don't need the psychiatric treatment". Treatment determination factors for mental illness were religion (p<.001), past history (p=.017), financial satisfaction (p=.048), previous history of suicidal attempts (p=.006), sleep disturbance (p<.001), expression of suicide (p=.010), and type of leaving the emergency room (p=.020, p<.001). Conclusion: Results suggest that people frequently misunderstand psychiatric treatment which leads to their refusal to accept psychiatric treatment. Therefore hospitals need to develop standard guidelines and procedures for suicidal attempters with the collaboration of emergency and psychiatry departments. In addition, medical teams need to provide attempters appropriate information and encourage them to actively seek psychiatric treatment.

• Journal of the Korean Society of School Health
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• v.28 no.2
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• pp.79-88
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• 2015

The purpose of the study was to investigate mental health and mental health-related factors of adolescents with allergic diseases. Methods: The subjects were 72,060 middle and high school students, the data of whom were extracted from the 2014 Korean Youth' Risk Behavior Web-based Survey. Allergic diseases included asthma, allergic rhinitis and eczema. Mental health was measured by indicators such as perceived stress, depression, and suicidal ideation. To compare the mental health of adolescents who have allergic diseases with that of those who don't, the study used ${\chi}^2-test$ and calculated odds ratio (OR) and 95% confidence interval (CI). In addition, the study used ${\chi}^2-test$and multiple logistic regression, calculating OR and 95% CI, to analyze the association between mental health and allergic diseases and other variables. Results: Of 72,060 adolescents who participated in the study, 51.6% had allergic diseases(asthma 9.2%, allergic rhinitis 32.2%, eczema 23.9%). And 37.1% reported perceived stress, 26.6% depression, and 13.1% suicidal ideation. The adolescents with allergic diseases, compared to the adolescents without allergic diseases, were 1.26 times, 1.28 times, and 1.29 times more likely to experience perceived stress, depression, and suicidal ideation, respectively. The mental health-related factors of adolescents with allergic diseases were school type, sex, socioeconomic status, and academic performance. Conclusion: The adolescents with allergic diseases had poorer mental health than the adolescents without the diseases. Further studies should be done to verify this. And based on the study's findings, school-based intervention programs for mental health of adolescents with allergic diseases need to be developed.

• The Journal of Korean Society for School & Community Health Education
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• v.23 no.4
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• pp.49-61
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• 2022

Objectives: It is reported that the depression of women with disabilities is higher than that of men with disabilities and people with disabilities. Therefore, the purpose of this study is to identify the depression level and influencing factors of middle-aged women with disabilities. Method: For this study, the 2020 survey on the disabled was used. The subjects were 2,546 middle-aged and disabled women over the age of 40 who responded to the survey. For data analysis, SPSS Window 26.0 program was used. Descriptive analysis, chi-square test, and multiple logistic analysis were performed to identify factors affecting depression in middle-aged women with disabilities. Results: In this study, marital status, subjective economic status, disability type, subjective health status, subjective obesity, chronic disease, exercise, stress and suicidal ideation, and self-going ability variables of middle-aged and elderly women with disabilities were found to be related to depression. Factors affecting the depression of middle-aged women with disabilities were analyzed to be marital status, smoking, stress, and suicidal ideation variables. Conclusion: Stress and suicidal ideation should be reduced to effectively reduce depression and improve depression in middle-aged and elderly women with disabilities. And the development and application of health education and programs that can promote mental health are required.

• Health Policy and Management
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• v.34 no.2
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• pp.129-140
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• 2024

Background: The mental health issues caused by trauma can manifest differently depending on the characteristics of the traumatic event. Particularly, individuals who have experienced sexual trauma are known to have more negative mental health outcomes compared to those who have experienced non-sexual trauma. The mental health issues of individuals who have experienced sexual trauma are severe, and new forms of threats, such as digital sexual crimes, are emerging. This study aimed to investigate whether the type of traumatic event, particularly focusing on sexual trauma events, contributes to differences in mental health outcomes and to identify factors influencing suicidal ideation and potential post-traumatic stress disorder (PTSD) risk. Methods: Based on an online survey conducted nationwide among adults aged 20 to 50, participants were categorized based on the type of trauma they experienced (sexual trauma events and non-sexual trauma events). The study conducted propensity score matching (PSM) using demographic factors (sex, age group, subjective economic status, and marital status) and resilience protective factors (cognition of recoverability, social support, and protection experiences in childhood) as control variables, excluding the experience of sexual trauma events, to investigate their potential impact on mental health (suicidal ideation and potential PTSD risk). Subsequently, binary logistic regression analysis was conducted to identify factors influencing mental health. Results: Even after PSM, individuals who experienced sexual trauma exhibited more negative outcomes in terms of suicidal ideation and potential PTSD risk compared to those who experienced non-sexual trauma. The results of binary logistic regression analysis showed that sexual trauma survivors were 1.9 times more likely to have suicidal thoughts (odds ratio [OR], 1.911) and 2.5 times more likely to have a potential PTSD risk (OR, 2.472). Furthermore, as resilience protective factors became more negative, the likelihood of suicidal ideation and potential PTSD risk increased. Conclusion: This study emphasizes the importance of understanding and supporting individuals who have experienced sexual trauma, highlighting the necessity for strategies aimed at mitigating suicidal ideation and potential PTSD risk among sexual trauma survivors, while also facilitating recovery through the promotion of resilience protective factors.

• The Journal of Korean Society for School & Community Health Education
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• v.20 no.2
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• pp.25-36
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• 2019

Purpose: The purpose of this study was to examine the factors affecting of health screening among persons with disabilities. Method: The study examines the factors affecting of health screening using over 20 years of age who participated in the 2017 National survey of the disabled data. Subjects were 6,332 person with disabilities over 20 years of age. Data were analyzed using descriptive statistics, X2-test, multiple logistic regression with the SPSS win 21.0 program. Results: Health screening among persons with disabilities is differentiated with education level, marital status, Subjective House economic status, Health insurance, Economic activity, Type of disability, Grade of disability, Stress recognition, Depressive symptom, Suicidal thinking, Suicidal attempt, and grade of disability. The significant predictors of the health screening were age, Subjective House economic status, Economic activity, and Grade of disability. Conclusion: We should consider age, disability level, and economic level when developing a screening program for people with disabilities. Especially, the development and promotion of the health screening program for persons with disabilities and related education are required.

• Journal of Pharmaceutical Investigation
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• v.33 no.4
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• pp.267-272
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• 2003

Herpes simplex virus (HSV) thymidine kinase (TK) has been widely used for suicidal gene therapy in combination with nucleoside analogs such as ganciclovir (GCV). The use of HSV-TK is limited due to the side effect of GCV at high concentrations. Previous studies showed that stable transfectants of mutant HSV-TK with enhanced affinity to GCV were killed at lower GCV concentrations. In this study, we tested whether mutant HSV-TK can provide enhanced suicidal effect when transiently transfected with Epstein-Barr virus (EBV)-based plasmid. EBV-based plasmid which contains OriP and EBNA-1 sequence is well known for a stable episomal maintenance in human cells. Optimal transfection condition was assessed for SNU-638 gastric cancer cell line using polyetylnimine (PEI). Maximum transfection efficiency was achieved when DNA:PEI was 1:3 (w/v). Cytotoxicities of mutant and wild type HSV-TK were compared before and after partially selecting transfected cells. The cells were sensitive to $100\;{\mu}g/ml$ hygromycin. Following GCV treatment, more cells were killed after hygromycin selection than before selection. The mutant HSV-TK showed enhanced cytotoxicity compared with the wild type HSV-TK. Our results suggest that the EBV-based plasmid encoding mutant HSV-TK may be useful to treat the diseases caused by uncontrolled cell proliferation such as cancer and rheumatoid arthritis.

• The Journal of the Korea Contents Association
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• v.19 no.3
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• pp.624-634
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• 2019

This study was conducted in order to figure out sexual experience among in Korean adolescents and its affecting factors. For the research method, it was a secondary analysis using raw data from the 13th(2017) Youth Risk Behavior Web-based Survey Data and the data from 62,276 adolescents were used for the analysis in this study. For the data analysis, frequency analysis, ${\chi}^2$-test, and logistic regression analysis were conducted by using SPSS 23.0 program, As a result of the research, the factors on sexual experience in male students included grade, school record, living type, economic state, depression, perceived stress, suicidal ideation, drinking, smoking, drug, and experience of sex education(p<.001) while those in female students included grade, living type, father's education, economic state, depression, suicidal ideation, drinking, smoking, drug, and experience of sex education(p<.001). Therefore, it is necessary to approach for helping from clinical settings, communities, and school healthcare through effective education and programs for preventing sexual problems, which reflect the factors associated with sex experience among adolescents in future.

• 한국노년학
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• v.38 no.2
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• pp.271-290
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• 2018

The study aims to analyze the effects of socio-economic deprivation on suicidal ideation. The analysis data were used as a guide for Korea Welfare Panel Study 9. the frequency analysis, mean difference analysis, correlation analysis, and logistic regression were performed by SPSS programs. The results of analysis are as follows. First, The results of frequency analysis by deprivation type showed a high frequency of deprivation in the following order. Experience of not receiving a public pension, experience of being able to work but unemployed, experience of not being able to eat a balanced diet due to financial difficulties, and experience where you had nothing to eat but no more money to buy. Second, the average difference analysis shows that when a person does not have a spouse, the lower the academic background and the income level, the higher the likelihood of suicide. Third, regression analysis shows that the following deprivation patterns have a statistically significant effect on older adults' thoughts of suicide. Experience in which the respondents or their family could not go to hospital because they had no money, experience that move house because is back rent more than 2 months or can not pay rent, experience that they could not afford to buy food and eat well-balanced meals, experience of failing to pay your bills on time, experience of being able to work but not having a job, and experience in which financial difficulties left them short of food and no money to live. Based on such research results, some policy measures, such as the expanding management of medical care benefits cases, the improvement of elderly housing, residential conditions and the diet survey for the elderly, and the expansion of measures to support elderly people's tax rates, were proposed.

• 한국노년학
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• v.37 no.1
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• pp.173-200
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• 2017

This study is designed to verify the actual effect on the prevention of the elderly suicide of the integrated crisis intervention service which has been widely provided across all local communities in Gyeonggi-province focusing on the integrated crisis intervention model developed for the prevention of elderly suicide. The integrated crisis intervention model for the local communities and its manual were developed for the prevention of elderly suicide by integrating the crisis intervention theory which contains local community's integrated system approach and the stress vulnerability theory. For the analysis of the effect, the geriatric depression and suicidal ideation scale was adopted and the data was collected as follows; The data was collected from 258 people in the first preliminary test. Then, it was collected from the secondary test of 184 people after the integrated crisis intervention service was performed for 6 months. The third collection of data was made from 124 people after 2 or 3 years later using the backward tracing method. As for the analysis, the researcher used the R Statistics computing to conduct the test equating, and the vertical scaling between measuring points. Then, the researcher conducted descriptive statistics analysis and univariate analysis of variance, and performed multi-level modeling analysis using Bayesian estimation. As a result of the study, it was found out that the integrated crisis intervention model which has been developed for the elderly suicide prevention has a statistically significant effect on the reduction of elderly suicide in terms of elderly depression and suicide ideation in the follow-up measurement after the implementation of crisis intervention rather than in the first preliminary scores. The integrated crisis intervention model for the prevention of elderly suicide was found to be effective to the extent of 0.56 for the reduction of depression and 0.39 for the reduction of suicidal ideation. However, it was found out in the backward tracing test conducted 2-3 years after the first crisis intervention that the improved values returned to its original state, thus showing that the effect of the intervention is not maintained for long. Multilevel analysis was conducted to find out the factors such as the service type(professional counseling, medication, peer counseling), characteristics of the client (sex, age), the characteristics of the counselor(age, career, major) and the interaction between the characteristics of the counselor and intervention which affect depression and suicidal ideation. It was found that only medication can significantly reduce suicidal ideation and that if the counselor's major is counseling, it significantly further reduces suicidal ideation by interacting with professional counseling. Furthermore, as the characteristics of the suicide prevention experts are found to regulate the intervention effect on elderly suicide prevention in applying integrated crisis intervention model, the primary consideration should be given to the counseling ability of these experts.

• Journal of the Korean Society of School Health
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• v.35 no.3
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• pp.92-103
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• 2022

Purpose: The purpose of this study was to prepare basic data for education and policy proposals related to enhancement of happiness by identifying factors affecting the subjective happiness among Korean adolescents by family type. Methods: The study was a secondary analysis using the raw data of the 16th Youth Risk Behavior Web-based Survey (2020). A complex sample multiple logistic regression analysis was conducted to identify factors affecting adolescent happiness by family type. Results: As a result, the factors that commonly affect the subjective happiness of adolescents for all family types were identified as economic status, academic performance, perceived stress, and loneliness. Additional factors that affect the subjective happiness of adolescents of both Korean two-parent and single parent families were sleep and subjective health status. Financial assistance, number of toilets, breakfast, exercise, depression, suicidal ideation, and suicide attempt were also reported for Korean two-parent families. Conclusion: This study provided empirical basic data for enhancing adolescent happiness in consideration of priority targets and family composition characteristics by identifying factors affecting subjective happiness by family type. Adolescent happiness is a factor that should be actively pursued at home, school, and society, and it should be the goal of education for holistic growth of students.