• Title/Summary/Keyword: succinate

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Synthesis and Properties of Glycidyl Succinate Type Cationic Gemini Surfactant (2-메틸숙신산을 이용한 에스테르계 제미니 양이온 계면활성제의 합성 및 물성)

  • Park, Jong-Kwon;Kim, Won-Kyun;Jeong, Noh-Hee
    • Journal of the Korean Applied Science and Technology
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    • v.30 no.2
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    • pp.312-319
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    • 2013
  • This study is to do with the synthesis of glycidyl succinate cationic gemini surfactant. The gemini surfactant was synthesized with using 2-methyl disodium succinate, epichlorohydrine and N,N-dimethyl dodecyl amine. The target material was confirmed by FT-IR, $^1H$-NMR and was tested their properties. Surface active properties such as surface tension, evaluated cmc, emulsing properties, foaming properties were measured respectively at given conditions. The surface tensions for the aqueous solution of gemini surfactant were 33~34 dyne/cm and their cmc values evaluated by surface tension method were $10^{-4}{\sim}10^{-3}mol/L$. Emulsing properties of gemini surfactant was better in organic solvent and foaming power was confirmed good stability.

Synthesis and Biodegradation Behavior of Poly(ethylene terephthalate) Oligomers (폴리(에틸렌 테레프탈레이트)(PET) 올리고머의 합성과 생분해 거동)

  • Lee, Chan-Woo;Chung, Jin-Do
    • Polymer(Korea)
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    • v.33 no.3
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    • pp.198-202
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    • 2009
  • Oligo(ethylene terephthalate)(OET), oligo(ethylene succinate-co-terephthalate)(OEST) and oligo(butylene succinate-co-terephthalate)(OBST), which are part of the poly(ethylene terephthalate)(PET) oligomer, were synthesized. Degradation test of oligomers carried out by the presence of lipase PS. There were two objectives in the experiment: first, to measure the weight remaining of the PET oligomer as increasing degradation time, and second to examine the degradation mechanism by analyzing the resulting degraded product. In the synthesis of OEST and OBST, by controlling the feed ratio of both OEST and OBST, we were able to obtain oligomer of different composition ratios. The various composition ratios resulted in oligomer of vastly different thermal properties. We observed that both OEST and OBST were degraded using lipase PS, but as the composition of terephthalic acid was increased, the lipase PS became less effective. We confirmed that the lipase PS easily decomposed polyester of the aliphatic compound.

Repression of Cyclohexanol Dehydrogenase in Acinetobacter calcoaceticus C10 (Acinetobacter calcoaceticus C10에서 Cyclohexanol Dehydrogenase의 생합성 억제)

  • Park, Heui Dong;Park, Jong Sung;Rhee, In Koo
    • Current Research on Agriculture and Life Sciences
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    • v.5
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    • pp.68-74
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    • 1987
  • The growth of A calcoaceticus C10 in CL medium was not increased by the addition of 0.5% E-capralactone or succinate, but increased by 0.2% adipate, xylose or even glucose which was not metabolized as a carbon source. The addition of 0.2% glucose after culture in CL medium for 6 hours increased the growth of A. colcoaceticus C10 twice as much as that in CL medium after culture for further 10 hours. Biosynthesis of cyclohexanol dehydrogenase in A. calcoaceticus C10 was not repressed by ${\varepsilon}$-caprolactone, succinate, xylose and glucose, but repressed by adipate which is endproduct of cyclohexanol metabolism. The induction of dehydrogenase by cyc1ohexanol in CL medium was not repressed completely by 0.1% adipate, but repressed almost completely by 0.2% adipate in A. calcoaceticus C10.

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Foaming of Poly(butylene succinate) with Supercritical Carbon Dioxide (초임계 이산화탄소를 이용한 Poly(butylene succinate) 발포)

  • Son, Jae-Myoung;Song, Kwon-Bin;Kang, Byong-Wook;Lee, Kwang-Hee
    • Polymer(Korea)
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    • v.36 no.1
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    • pp.34-40
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    • 2012
  • The foaming of poly(butylene succinate) (PBS) using supercritical $CO_2(scCO_2)$ was studied. In order to improve the melt strength, PBS was modified using the reactive compounding technique. Rapid decompression of $scCO_2$-saturated PBS at a temperature above the depressed $T_m$ yielded expanded microcellular foams. The resulting foam structure could be controlled by manipulating process conditions. Experiments varying the foaming temperature while holding other variables constant showed that higher temperatures produced larger cells and reduced cell densities. Higher saturated pressures led to higher nucleation densities and smaller cell sizes. Decreasing the rate of depressurization permitted a longer period of cell growth and therefore larger cells were obtained.

Effect of Temperature on Dicarboxylate Transport in Plasma Membrane Vesicles of Rabbit Proximal Tubule

  • Han, Kyung-Moon;Kim, Young-Hee;Woo, Jae-Suk;Kim, Yong-Keun
    • The Korean Journal of Physiology
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    • v.27 no.2
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    • pp.227-232
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    • 1993
  • The temperature dependence of $Na^+-dependent$ succinate uptake was studied in brush border (BBMV) and basolateral (BLMV) membrane vesicles isolated from the rabbit kidney cortex. The succinate uptake was markedly altered by temperature in a similar fashion in both membranes. The temperature dependence was characterized by a nonlinear Arrhenius plot with a break point at 22 and $25^{\circ}C$ for BBMV and BLMV, respectively. The activation energy was 3.91 and 17.09 kcal/mole at above and below the break point respectively, far BBMV; 2.65 and 14.05 kcal/mole, respectively, for BLMV. When temperature increased f개m 20 to $35^{\circ}C$, the Vmax of succinate transport increased from $3.49{\pm}0.11\;to\;5.90{\pm}0.86\;nmole/mg/5\;sec$ for BBMV and from $2.86{\pm}0.25\;to\;3.63{\pm}0.32\;nmole/mg/5\;sec$ for BLMV, with no change in Km in both membranes. These results suggest that renal dicarboxylate transport is similarly sensitive to a change in membrane physical state in BBMV and BLMV.

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Effects of Mitochondrial Reactive Oxygen Species on Neuronal Excitability in Rat Spinal Substantia Gelatinosa Neurons

  • Lee, Hae-In;Park, A-Reum;Chun, Sang-Woo
    • International Journal of Oral Biology
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    • v.37 no.1
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    • pp.17-23
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    • 2012
  • Recent studies indicate that reactive oxygen species (ROS) are critically involved in persistent pain primarily through spinal mechanisms, and that mitochondria are the main source of ROS in the spinal dorsal horn. To investigate whether mitochondrial ROS can induce changes in membrane excitability on spinal substantia gelatonosa (SG) neurons, we examined the effects of mitochondrial electron transport complex (ETC) substrates and inhibitors on the membrane potential of SG neurons in spinal slices. Application of ETC inhibitors, rotenone or antimycin A, resulted in a slowly developing and slight membrane depolarization in SG neurons. Also, application of both malate, a complex I substrate, and succinate, a complex II substrate, caused reversible membrane depolarization and enhanced firing activity. Changes in membrane potential after malate exposure were more prominent than succinate exposure. When slices were pretreated with ROS scavengers such as phenyl-N-tert-buthylnitrone (PBN), catalase and 4- hydroxy-2,2,6,6-tetramethylpiperidine-1-oxyl (TEMPOL), malate-induced depolarization was significantly decreased. Intracellular calcium above $100{\mu}M$ increased malateinduced depolarization, witch was suppressed by cyclosporin A, a mitochondrial permeability transition (MPT) inhibitor. These results suggest that enhanced production of spinal mitochondrial ROS can induce nociception through central sensitization.

Effects of organic compounds on the respiration of thiobacillus concretivorus Parker (Thiobacillus concretivorus Parker의 호흡에 미치는 유기물의 영향)

  • 하영칠;주동기
    • Korean Journal of Microbiology
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    • v.10 no.4
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    • pp.167-174
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    • 1972
  • Effects of 13 organic compounds including glucose, fructose, xylose, glutamate, succinate, malate, glycine, lactate, acetate, pyruvate, citrate, formate and cis-aconitate on the oxidation of thiosulfate and the availability of these compounds as the substrate for the respiration by Thiobacillus ocncretivorus, which is known to be an obligated autotroph, were studied. Malate nad glycine at 0.5 per cent concentration nearly doubled the thiosulfate oxidation compared to the control. No other organic substances enhanced the thiosulfate oxidation compared to the control. No other organic substances enhanced the thiosulfate oxidation. Moreover, some 30 to 40 per cent decrease was recorded by fructose, sulfate-salts medium, some 30 to 40 per cent decrease was recorded by fructose, citrate, xylose, malate, flucose, glutamate and succinate. No respiration could occur when formate and pyruvate were supplied as the substrate for respiration. But it was obvious that flucose, fructose, xylose, glutamate, malate, citrate and succinate could be used as the substrate for respiration to some extent, regarding the fact that some increase in respiration rates could be recorded compared to the result from the salts medium, where neither thiosulfate nor orgnic compounds were added. Thus, it was postulated that this organism could possibly be converted into mixotroph or hetrotroph if appropriate conditions could be prepared.

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Afforestation of a Brown Alga, Ecklonia cava Kjellman using a Biodegradable Polybutylene Succinate (생분해성 로프를 이용한 대형 갈조류 감태의 이식)

  • Baek, Jae-Min;Park, Seong-Wook;Hwang, Eun-Kyoung
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.42 no.5
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    • pp.523-526
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    • 2009
  • Biodegradable polybutylene succinate (BPS) multifilament were designed to degrade upon disposal by the action of afforestration of Ecklonia cava. Matured thalli of E. cava were collected at Jeju for zoospore collection and the substrate for zoospores were BPS multifilament (12 mm, 500 Td/96). The materials were made as nets of $1\;m^2$ with a cross stripes of 10 cm. The unit biodegradable nets bearing germlings of E. cava was moved into Wando where the place is conducting intensive seaweed cultivation in Korea for 5 months of nursery culture until they grew to 10 cm in length after which the nets were transplanted into the sea bed at Jeju at a depth of 12 m and the algal growth was monitored from May 2007 to December 2008. This is the first instance of using the BPS materials for seaweed afforestation to avoid any environmental problems.

Preparation and Characterization of High Molecular Weight Poly(butylene succinate)

  • Han, Yang-Kyoo;Kim, Sung-Rim;Kim, Jinyeol
    • Macromolecular Research
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    • v.10 no.2
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    • pp.108-114
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    • 2002
  • Poly(butylene succinate) (PBS) prepolymers were prepared by the condensation polymerization of 1,4-butanediol (1,4-BD) and succinic atid (SCA) in the presence of titanium (VI) isoproxide(TPI) catalyst. The PBS prepolymers reacted with 1,4-BD or SCA to obtain hydroxyl or carboxylic acid group terminated PBS. High molecular weight linear or branched PBS was synthesized by a coupling reaction between hydroxyl and carboxylic acid group terminated PBS, or by a branching reaction between carboxylic acid group terminated PBS and glycerol as a branching agent. The weight average molecular weight of the prepared linear or branched PBS was in the range of 100,000-220,000. Both melting point and thermal stability of the high molecular weight linear and branched PBSs were somewhat higher than those of general PBS. From a tensile behavior by Instron test, modulus, tensile strength and elongation at break improved with increase in the molecular weight of the prepared PBS through the coupling or the branching reaction. In particular, the high molecular weight linear PBS had about 2.5 times higher value in modulus than the branched one.

Studies on the Metabolism-Independent Calium Binding of the Rat Liver Mitochondria (흰쥐 肝미토콘드리아의 非代謝依存性 칼슘 結合에 관한 연구)

  • Kang, Shin-Sung;Ha, Doo-Bong
    • The Korean Journal of Zoology
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    • v.13 no.3
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    • pp.85-93
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    • 1970
  • Measurements were made of the $Ca^++$ uptake, oxygen consumption and ATPase activity of mitochondria extracted from the rat liver in sucrose-tris chloride medium. $Ca^++$ binding of mitochondria was not affected by the incubation temperature in the range of $0^\\circ - 37^\\circ C$. Succinate did not increase the amount of $Ca^++$ bound while it increased oxygen consumption highly. The presence of ATP in the incubation medium did not enhance the $Ca^++$ uptake either. Therefore, it is concluded that the initial binding of $Ca^++$ is independent on metabolism.

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