• The KIPS Transactions:PartD
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• v.9D no.1
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• pp.111-126
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• 2002

As the technical aspect of the web system development is, unlike the existing main frame or client/server environment, greatly influenced by the dynamic and variable factors and carried out in a comparatively short period, practical and efficient process to which the developer may adapt with ease is very much required for the web system development. However, while the technological substitute, language and architecture composition have been much discussed, in connection with web system development growing rapidly, standardized development process and its deliverables have been rarely discussed. This thesis analyzes problems of the existing web system development processes and as the substitutes for them, proposes web system development process based on the domain features derived from the concepts of iteration and increment. For the classification of domains, five domains in total are set by interlocking web system factors and web site types and the workflows for two domains applied to projects are incorporated focused on work content and deliverables. The proposed process applies to the development of intranet system and is compared with the existing web development processes by the measure classified into components and elements.

• The KIPS Transactions:PartB
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• v.10B no.5
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• pp.485-490
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• 2003

In this paper, we propose the possibility of introducing chaotic sequences into digital watermarking systems as potential substitutes to commonly used pseudo noise sequences. Chaotic sequences have several good properties including the availability of a great number of them, the ease of their generation, as well as their sensitive dependence on their initial conditions. And the quantization does not destroy the good property. So this paper proposes a method that transforms Hangul text to chaotic sequence. And we presents how the Hangul text is expressed by an implied data and the implied data is regenerated into the original text. In this paper, we use this implied Hangul text for watermarking.

• Korean Chemical Engineering Research
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• v.44 no.2
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• pp.114-120
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• 2006

Bismuth vanadate is one of the environmentally benign substitutes for conventional inorganic pigments composed of heavy metals. The effect of process parameters on the physical properties of bismuth vanadate pigment prepared from aqueous solutions of potassium vanadate and bismuth nitrate were experimentally examined. Two aqueous solutions were fed into precipitation chamber at the same flow rate, and precipitates were formed at primary pH of 4.5 and secondary pH of 7.0~7.5. After aging for 3 hours in reaction mixture, 3 hours' calcination at $400^{\circ}C$ gave bismuth vanadate pigment with a good color and hiding power. Increase in molybdenum concentration in reaction mixture increased the hiding power of the pigment, but the other minor constituents had minor effect on the physical properties of the pigment.

• Korean Journal of Air-Conditioning and Refrigeration Engineering
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• v.17 no.10
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• pp.883-890
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• 2005

In this study, 2 pure hydrocarbon refrigerants of R1270 (Propylene) and R290 (Propane) and 3 binary mixtures composed of R1270, R29O and R152a were tested in a refrigerating bench tester with a scroll compressor in an attempt to substitute R502 used in most of the low temperature applications. The test bench provided 3\sim3.5$ kW capacity and water and water/glycol mixture were employed as the secondary heat transfer fluids. All tests were conducted under the same external conditions resulting in the average saturation temperatures of -28 and $45^{\circ}C$ in the evaporator and condenser, respectively. Test results showed that all refrigerants tested had $9.6\sim18.7\%$ higher capacity and $17.1\sim27.3\%$ higher COP than R502. The compressor discharge temperature of R1270 was similar to that of R502 while those of all other refrigerants were $23.7\sim27.9\%$ lower than that of R502. For all alternative refrigerants, the amount of charge was reduced up to $60\%$ as compared to R502. Overall, these alternative refrigerants offer better system performance and reliability than R502 and can be used as long term substitutes for R502 due to their excellent environmental properties.

• Journal of Korean Clinical Nursing Research
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• v.26 no.2
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• pp.217-231
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• 2020

Purpose: To identify the clinical role of Advanced Practice Nurses (APN), and evaluate how other medical personnel perceive their work(difficulty, importance). Methods: A questionnaire survey was performed with 277 health care providers (APN 52, nurses 88, and medical doctors 137 [professors 51, fellows 44, & residents 42]) in a single, tertiary hospital. The questionnaire was categorized into 6 domains (total 40 tasks): 6 tasks on identifying health issues (A); 3 tasks on prescribing and conducting diagnostic tests (D); 18 tasks on disease treatment (T); 4 tasks regarding prescribing medicine (M); 3 tasks regarding medical collaboration (C); 6 tasks regarding patient education (E). The survey measured the frequency, difficulty, and importance of APN's clinical tasks, and evaluated the willingness of authorizing clinical tasks to APN. Results: The most frequent tasks for APN were A domain, lowest were T domain. The scores for perceived job difficulty were lower than those for job importance in all groups. The proportion of willingness to legally delegate clinical practices to APN was higher in A and E domains, but lower in D and T domains. However, professors, who spent the most time with APN, showed a higher willingness to legally delegate clinical practice. The participants favored medical doctors as substitutes for tasks which were not legislated for delegated job performance. Conclusion: In this study identified clinical roles that medical doctors considered possible for legal delegation to APN were identified. The results can be used as evidence for the legalization of the practice of APN.

• Maxillofacial Plastic and Reconstructive Surgery
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• v.30 no.4
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• pp.323-332
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• 2008

Aim of the study: Scaffolds are crucial to tissue engineering/regeneration. Biodegradable polymer/ceramic composite scaffolds can overcome the limitations of conventional ceramic bone substitutes such as brittleness and difficulty in shaping. In this study, poly(L-lactide)/hydroxyapatite(PLLA/HA) composite scaffolds were fabricated for in vivo bone tissue engineering. Material & methods: In this study, PLLA/HA composite microspheres were prepared by double emulsion-solvent evaporation method, and were evaluated in vivo bone tissue engineering. Bone marrow mesenchymal stem cell from rat iliac crest was differentiated to osteoblast by adding osteogenic medium, and was mixed with PLLA/HA composite scaffold in fibrin gel and was injected immediately into rat cranial bone critical size defect(CSD:8mm in diameter). At 1. 2, 4, 8 weeks after implantation, histological analysis by H-E staining, histomorphometric analysis and radiolographic analysis were done. Results: BMP-2 loaded PLLA/HA composite scaffolds in fibrin gel delivered with osteoblasts differentiated from bone marrow mesenchymal stem cells showed rapid and much more bone regeneration in rat cranial bone defects than control group. Conclusion: This results suggest the feasibility and usefulness of this type of scaffold in bone tissue engineering.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• v.45 no.6
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• pp.332-342
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• 2019

Objectives: Socket grafting is vital to prevent bone resorption after tooth extraction. Several techniques to prevent resorption have been described, and various bone graft substitutes have been developed and used with varying success. We conducted this pilot study to evaluate the performance of nanohydroxyapatite (nHA) derived from chicken eggshells in socket preservation. Materials and Methods: This was a prospective, single center, outcome assessor-blinded evaluation of 23 sockets (11 patients) grafted with nHA and covered with platelet-rich fibrin (PRF) membrane as a barrier. Bone width and radiographic bone density were measured using digital radiographs at 1, 12, and 24 weeks post-procedure. Postoperative histomorphometric and micro-computed tomography (CT) evaluation were performed. The study protocol was approved by the Institutional Ethics Committee. Results: All patients had uneventful wound healing without graft material displacement or leaching despite partial exposure of the grafted socket. Tissue re-epithelialized with thick gingival biotype (>3 mm). Width of the bone was maintained and radiographic density increased significantly with a trabecular pattern (73.91% of sockets) within 12 weeks. Histomorphometric analysis showed 56.52% Grade 3 bone formation and micro-CT analysis revealed newly formed bone with interconnecting trabeculae. Conclusion: Use of a PRF membrane with nHA resulted in good bone regeneration in sockets. Use of a PRF membrane prevents periosteal-releasing incisions for primary closure, thereby facilitating the preservation of keratinized mucosa and gingival architecture. This technique, which uses eggshell-derived nHA and PRF membrane from the patient's own blood, is innovative and is free of disease transfer risks. nHA is a promising economic bone graft substitute for bone regeneration and reconstruction because of the abundant availability of eggshell waste as a raw material.

• The Journal of Advanced Prosthodontics
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• v.7 no.2
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• pp.93-97
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• 2015

PURPOSE. Xerostomia can diminish the quality of life, leads to changes in normal chemical composition of saliva and oral microbiata, and increases the risk for opportunistic infections, such as Candida albicans. Various artificial salivas have been considered for patients with xerostomia. However, the knowledge on the antifungal and antiadhesive activity of artificial saliva substitutes is limited. The aim of the present study was to evaluate influence of two artificial salivas on the adhesion of Candida albicans to the polymethylmethacrylate disc specimens. MATERIALS AND METHODS. Two commercial artificial salivas (Saliva Orthana and Biotene Oral Balance Gel) were selected. 45 polymethylmethacrylate disc specimens were prepared and randomly allocated into 3 groups; Saliva Orthana, Biotene-Oral Balance gel and distilled water. Specimens were stored in the artificial saliva or in the sterile distilled water for 60 minutes at $37^{\circ}C$. Then they were exposed to yeast suspensions including Candida albicans. Yeast cells were counted using ${\times}40$ magnification under a light microscope and data were analysed. RESULTS. Analysis of data indicated statistically significant difference in adhesion of Candida albicans among all experimental groups (P=.000). Findings indicated that Saliva Orthana had higher adhesion scores than the Biotene Oral Balance gel and distilled water (P<.05). CONCLUSION. In comparison of Saliva Orthana, the use of Biotene Oral Balance Gel including lysozyme, lactoferrin and peroxidase may be an appropriate treatment method to prevent of adhesion of Candida albicans and related infections in patients with xerostomia.

• Journal of Periodontal and Implant Science
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• v.42 no.2
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• pp.50-58
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• 2012

Purpose: This study evaluated histologically the tissue responses to and the effects of a customized nano-hydroxyapatite (n-HA) block bone graft on periodontal regeneration in a one-wall periodontal-defect model. Methods: A customized block bone for filling in the standardized periodontal defect was fabricated from prefabricated n-HA powders and a polymeric sponge. Bilateral $4{\times}{\times}4{\times}5$ mm (buccolingual width${\times}$mesiodistal width${\times}$depth), one-wall, critical-size intrabony periodontal defects were surgically created at the mandibular second and fourth premolars of five Beagle dogs. In each dog, one defect was filled with block-type HA and the other served as a sham-surgery control. The animals were sacrificed following an 8-week healing interval for clinical and histological evaluations. Results: Although the sites that received an n-HA block showed minimal bone formation, the n-HA block was maintained within the defect with its original hexahedral shape. In addition, only a limited inflammatory reaction was observed at sites that received an n-HA block, which might have been due to the high stability of the customized block bone. Conclusions: In the limitation of this study, customized n-HA block could provide a space for periodontal tissue engineering, with minimal inflammation.

• Journal of Periodontal and Implant Science
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• v.37 no.2
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• pp.151-164
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• 2007

Objective: The sinus floor elevation procedures have been used to facilitate implant placement in the severely atrophic posterior maxilla. Many variables may have an influence on the outcomes of the sinus floor elevation in combination with implant treatment. The aim of this study was to analyze survival rate of implants placed in the edentulous maxillae of patients in whom sinus floor elevation was undertaken according to variables. Materials and Methods: It consisted of 96 patients(50 male and 46 female), ranging in age from 31 to 70 years(mean 49 years), who underwent sinus floor elevation procedure(94 implants in left side and 106 implants in right side) from 2001 to 2002. A total of 200 implants were placed in the grafted sinus(73 implants in lateral approach and 127 implants in crestal approach). All implants were restored by fixed prosthesis. All patients were healthy. Follow-up periods for implants were between 48 to 60 months. Results: The cumulative survival rate of implants was 91.5%. Gender, age and operation site did not have an influence on the survival rate. There was statistically significant differences for the implants which placed in less than 4 or 5 rom residual bone height, the survival rate was 60%, 81.4% respectively (p<0.05). There was no statistically significant difference of implants survival rate ac- cording to approach technique. The survival rate for 100% autogenous bone grafts was lower with respect to composite grafts containing autogenous bone and 100% substitutes. The survival rate for hydroxyapatite-coated implants was statistically significant lower than other textured group (p<0.05). Conclusion: Residual bone height, surface texture and graft materials have an influence on the survival rate. To use autogenous bone as a part of a composite bone replacement, implant texture which leads to more favorable implant-bone interface were necessary. To determine residual bone height for initial implant stability was important.