• International Journal of Advanced Culture Technology
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• 제7권1호
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• pp.20-27
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• 2019

This study was designed to examine the affect health promotion behavior to emotional happiness for 20-30's in Korea through cross-sectional descriptive research. There were a total of 279 people who participated in this study, 198(71.0%) were males and 81(29.0%) were females. The data collection period was from December 1 to 15, 2018. The tools used to measure health promotion behaviors were HPB (Health Promotion Behavior) developed by Walker et al., and emotional happiness was PANAS (Positive and Negative Affect Scale) by Developed by Watson et al., All data was analyzed using SPSS 18.0 program. As a result of analysis, 62 (49.6%) were solving interpersonal problems and stress relief while drinking, and the people who ate twice a day were most frequent. In conclusion, health promotion behaviors have a strong correlation with emotional happiness. Based on the above results, it was suggested that the program of happiness for lining in the 20-30s age groups should strengthen the contents of health responsibility, guidance of substance abuse, formation of social relations and self actualization.

• 한국산학기술학회논문지
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• 제16권5호
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• pp.3333-3343
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• 2015

본 연구의 목적은 한국 청소년의 성경험과 위험 성행동을 중심으로 약물사용 관련요인을 파악하기 위함이다. 본 연구는 2011년 제7차 청소년건강행태온라인조사의 자료를 활용한 2차 분석연구로, 익명성 자기기입식 온라인 조사를 통해 자발적으로 참여한 청소년의 총 75,643명의 자료가 분석에 이용되었으며, 복합표본분석 방법으로 서술통계, rao-Scott ${\chi}^2$, 로지스틱회귀분석을 이용하였다. 연구결과, 약물사용은 동성과의 성경험(adjusted OR=5.691; 95% CI=4.223-7.670)과 이성과의 성경험(adjusted OR=21.180; 95% CI=14.704-30.507) 및 성폭행(adjusted OR=9.936; 95% CI=7.217-13.680), 데이트 성폭행(adjusted OR=16.979; 95% CI=11.648-24.751), 음주 후의 성관계(adjusted OR=6.564; 95% CI=3.986-10.810), 예상치 못한 임신(adjusted OR=18.628; 95% CI=8.476-40.936), 성병(adjusted OR=21.872; 95% CI=13.920-34.367)과 같은 위험 성행동과 유의한 관련성이 있는 것으로 나타났다. 이러한 연구결과는 약물사용 청소년은 위험 성행동을 경험할 개연성이 높은 것으로 보여준다. 그러므로 한국 청소년의 약물사용은 성문제와 함께 그 해결방안이 모색되어야 하고, 가족과 학교 모두의 참여에 근거한 신체적, 심리적, 사회적 측면의 문제해결을 위한 중재가 개발되어 적용되어야 할 것이다.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• 제8권2호
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• pp.199-206
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• 1997

저자들은 일반 청소년에 있어서 부모폭행의 빈도를 알아보고, 부모를 폭행하는 위험인자를 밝히기 위하여, 서울시내 중학생 1345명을 대상으로 자기 보고식 설문지를 이용한 조사를 통해 다음과 같은 결과를 얻었다. 1) 일반 청소년에서 아버지, 어머니에게 각각 욕설이나 폭언을 한적이 있는 경우는 7%, 10%；화가 나서 문을 쾅 닫거나 물건을 던진 적이 있는 경우는 40%, 45%；신체적으로 폭행한 적이 있는 경우는 2.8%, 2.3%；폭행하여 다치게 한적이 있는 경우는 2.3%, 1.2%；칼이나 흉기 등으로 위협한 적이 있는 경우는 0.7%, 0.4%였다. 2) 청소년의 부모 폭행과 연관성이 있는 요인은 과거 일생 동안의 폭력에의 노출(p=0.0001), 최근 1년간 가정내 폭력에의 노출(p=0.0002), 청소년 자신이 술, 담배, 약물남용의 문제가 있는 경우(p=0.0003), 부모가 음주와 관련되어 다툼이 있는 경우(p=0.0001)인 것으로 나타났다. 본 연구를 통해 청소년의 부모폭행이 드물지 않게 발생하는 문제임을 알 수 있었고, 청소년의 부모폭행이 가정내 폭력, 청소년의 물질남용, 부모의 음주와 관련되어 있어 이러한 문제를 가진 고위험군에 대한 예방적 개입이 필요함이 시사되었다.

• Biomolecules & Therapeutics
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• 제30권3호
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• pp.238-245
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• 2022

Previous reports have demonstrated that genetic mechanisms greatly mediate responses to drugs of abuse, including methamphetamine (METH). The circadian gene Period 2 (Per2) has been previously associated with differential responses towards METH in mice. While the behavioral consequences of eliminating Per2 have been illustrated previously, Per2 overexpression has not yet been comprehensively described; although, Per2-overexpressing (Per2 OE) mice previously showed reduced sensitivity towards METH-induced addiction-like behaviors. To further elucidate this distinct behavior of Per2 OE mice to METH, we identified possible candidate biomarkers by determining striatal differentially expressed genes (DEGs) in both drug-naïve and METH-treated Per2 OE mice relative to wild-type (WT), through RNA sequencing. Of the several DEGs in drug naïve Per2 OE mice, we identified six genes that were altered after repeated METH treatment in WT mice, but not in Per2 OE mice. These results, validated by quantitative real-time polymerase chain reaction, could suggest that the identified DEGs might underlie the previously reported weaker METH-induced responses of Per2 OE mice compared to WT. Gene network analysis also revealed that Asic3, Hba-a1, and Rnf17 are possibly associated with Per2 through physical interactions and predicted correlations, and might potentially participate in addiction. Inhibiting the functional protein of Asic3 prior to METH administration resulted in the partial reduction of METH-induced conditioned place preference in WT mice, supporting a possible involvement of Asic3 in METH-induced reward. Although encouraging further investigations, our findings suggest that these DEGs, including Asic3, may play significant roles in the lower sensitivity of Per2 OE mice to METH.

• 대한간호학회지
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• 제23권3호
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• pp.487-503
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• 1993

This study was designed to investigate the situation of adolescent drug use in Seoul, and to com-pare this with the 1991 survey in order to better understand the present situation. The subject for this study were 1000 students in High School and Middle School. The data were collected during the period from september 1, 1992 to December 30, 1992. The guestionnaire developed by Kim So Ya Ja (1991) to survey adolescent drug use was used. The data was analyzed using descriptive statistics, 1-test and ANOVA with the SPSS program. The results of this study can be summarized as follows 1. Prevalence of Substance use : Antihistamines were used by 0.3% of adolescent, Sedatives 0.6%, Stimulants 8.1%, Hallucinogens 0.9%, Inhalants 3.2%, Narcotics 1.7%, and Analgetics 154.3%. 2. Trend in substance use compared to the 1991 surbey : Alcohol use increased from 52.8% to 63.7% and narcotics from 0.6% to 1.7%, while Smeking, Analgetics, Antihistamines, Sedatives, and Inhalants showed a decrease. 3. Smoking and Alcohol use : Twenty five percent of school adolescent had experienced cigarette smoking and 63.7% of school adolescent had experienced alcohol use. 4. Motives for drug use : The highest was avoidence of sleep at 49.4% and the next highest was adventure seeking at 27.7%. As to feeling after drug use, 34.3％ felt apathy, 22.8% had feelings of sleepiness and unconsciousness. 5. Places were dreg were purchased : The most frequent was the drug store (78.3%) and 84.4% of the respondents answered that drug purchase was easy and 86.7% that drug use was mainly at home. 6. Related Variables : There was a statistically significent high score for drug and alcohol use by adolescents whose fathers used drugs. (PC.05) In conclusion, adolescents in Seoul showed in decrease in the tendency to use drugs compared to the 1991 survey, however drugs which are habit-forming and lead to dependency are still being abused. Therefore, counter-plans and preventive stratiges are important.

• 대한수의학회지
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• 제63권3호
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• pp.21.1-21.6
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• 2023

The increasing prevalence of toxic substance-exposure in pets in South Korea endangers the health and safety of numerous companion animals, and has become a cause for concern. Notably, the annual incidence of forensic analysis in pets has increased by more than 150% in South Korea, mainly in populous regions such as Seoul, Incheon, and Gyeonggi. In response to this growing issue, veterinary forensic examinations were conducted on 549 dogs and cats from 2019 to 2022. This study revealed the presence of various toxic substances, including pesticides, insecticides, and drugs such as analgesics, anesthetics, antidepressants, and muscle relaxants, in pets. Among the 38 different toxins identified in pets, coumatetralyl, methomyl, terbufos, and buprofezin were the most frequently detected. In this study, toxic substances for pets were identified based on the "toxic agent list for humans," developed by the National Forensic Services, because no list of toxic agents for animals currently exists and data regarding potentially toxic substances for dogs and cats is limited. This is one of the limitations of this study, and necessitates the establishment of a toxic agent list for animals. Continued monitoring and research is also recommended to reveal the incidence, causes, and solutions of toxicity in animals.

• 대한간호학회지
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• 제35권2호
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• pp.262-269
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• 2005

Purpose: The purpose of this study was to develop a health education program for child care workers of infants, toddlers and preschoolers to improve their care ability. The program provided child care teachers and children with information on how to take care of their health. Method: This program development was based on a systematic design of instruction by Dick & Carey(1996). The process included a review of literature, setting an instructional goal, getting advice from various experts, designing instruction and instructional medias, designing formative evaluation, revising the program and making a summative evaluations. Result: The products of this program were the 'Teachers Guide Book & CD-ROM.' The guide book included health education programs for infants, toddlers and preschoolers. The infant program included a basic baby care program for teachers. The toddlers and preschoolers program included basic health promotion, dental health, nutrition management, communicable disease prevention, substance abuse prevention and a safety program. Conclusion: These programs provided a systematic content of health education for children and their teachers, and useful data which can be applied to child care centers.

• Mass Spectrometry Letters
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• 제9권3호
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• pp.86-90
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• 2018

Methallylescaline, 2-(3,5-dimethoxy-4-[(2-methylprop-2-en-1-yl)oxy]phenyl)ethanamine, is a new psychoactive substance with potent agonist of 5-HT receptor, but there is little information on its pharmacological effect, metabolism, and toxicity. It is necessary to characterize the metabolic profiling of methallylescaline in human hepatocytes using liquid chromatography-high resolution mass spectrometry. Methallylescaline was metabolized to three hydroxy-methallylescaline (M1-M3) and dihydroxy-methallylescaline (M4) via hydroxylation in human hepatocytes. CYP2D6, CYP2J2, CYP1A2, and CYP3A4 enzymes were responsible for the metabolism of methallylescaline. The metabolites as well as methallylescaline would be used for monitoring the abuse of methallylescaline.

• Asian Pacific Journal of Cancer Prevention
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• 제15권22호
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• pp.10033-10038
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• 2014

The aim of this study was to determine the prevalence of tobacco use, beliefs and risk awareness and psychosocial correlates of tobacco use among university students in 24 low, middle and emerging economy countries. Using anonymous questionnaires, data were collected from 16953 undergraduate university students (mean age 20.9, SD=2.9) from 25 universities in 24 countries across Asia, Africa and the Americas. Results indicate that overall 13.3% of the university students were current tobacco users, 22.4% for men and 6.6% for women, ranging from 3.8% in Singapore to 32.5% in Cameroon. The risk awareness of the smoking lung cancer link was 83.6%, while the risk awareness of the smoking heart disease link was 46.5%. Multivariate logistic regression found that older age, male gender, having a wealthy family background, living in a low income country, residing off campus on their own, poor beliefs in the importance not to smoke, awareness of the smoking heart disease link, hit by a sexual partner, depressive symptoms, and substance use (binge drinking and illicit drug use) were associated with current tobacco use.

• Journal of Korean Neurosurgical Society
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• 제57권5호
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• pp.379-385
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• 2015

Chronic subdural hematomas mainly occur amongst elderly people and usually develop after minor head injuries. In younger patients, subdural collections may be related to hypertension, coagulopathies, vascular abnormalities, and substance abuse. Different techniques can be used for the surgical treatment of symptomatic chronic subdural hematomas : single or double burr-hole evacuation, with or without subdural drainage, twist-drill craniostomies and classical craniotomies. Failure of the brain to re-expand, pneumocephalus, incomplete evacuation, and recurrence of the fluid collection are common complications following these procedures. Acute subdural hematomas may also occur. Rarely reported hemorrhagic complications include subarachnoid, intracerebral, intraventricular, and remote cerebellar hemorrhages. The causes of such uncommon complications are difficult to explain and remain poorly understood. Overdrainage and intracranial hypotension, rapid brain decompression and shift of the intracranial contents, cerebrospinal fluid loss, vascular dysregulation and impairment of venous outflow are the main mechanisms discussed in the literature. In this article we report three cases of different post-operative intracranial bleeding and review the related literature.