• Title/Summary/Keyword: structural non-response

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A Study on Disaster Prevention Activities at the Village Level to Preserve the Historical Environment: Focusing on Employee Residence Area in Soje-dong, Daejeon (역사환경 보존을 위한 마을단위 방재 활동 연구: 대전 소제동 관사촌을 중심으로)

  • Lee, Sanghee
    • Journal of Internet of Things and Convergence
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    • v.7 no.4
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    • pp.69-75
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    • 2021
  • This study investigated the status of disaster response, focusing on modern architecture. The modern architecture is drawing more attention and being more used in the local community among the architectural heritage in downtown collective. The railway employee residence area in Soje-dong, Daejeon is a collective building group, and the efforts to evaluate and preserve its historical, cultural, and architectural values have been underway. However, the area is now an undesignated cultural property that does not receive institutional protection. It carries significance in preserving it as a collective building group. Yet, since the main structure is made of wood, the risk of being destroyed by fire or disaster is high, and disaster prevention measures are insufficient. Therefore, this study examined the structural and non-structural conditions such as the arrangement and architectural characteristics of official residence buildings, and looked into measures of the construction of a disaster prevention system and residents' participation. To preserve the urban historical environment created as a collective architectural heritage, it is necessary that the area reinforces its own disaster prevention capabilities, such as establishing an effective disaster prevention system considering village characteristics, strengthening disaster prevention capabilities based on residents' participation, and forging formal and informal governance in the local community.

The Role of DNA Binding Domain in hHSF1 through Redox State (산화환원에 따른 hHSF1의 DNA binding domain의 역할)

  • Kim, Sol;Hwang, Yun-Jeong;Kim, Hee-Eun;Lu, Ming;Kim, An-D-Re;Moon, Ji-Young;Kang, Ho-Sung;Park, Jang-Su
    • Journal of Life Science
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    • v.16 no.6
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    • pp.1052-1059
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    • 2006
  • The heat shock response is induced by environmental stress, pathophysiological state and non-stress conditions and wide spread from bacteria to human. Although translations of most proteins are stopped under a heat shock response, heat shock proteins (HSPs) are produced to protect cell from stress. When heat shock response is induced, conformation of HSF1 was changed from monomer to trimer and HSF1 specifically binds to DNA, which was called a heat shock element(HSE) within the promoter of the heat shock genes. Human HSF1(hHSFl) contains five cysteine(Cys) residues. A thiol group(R-SH) of Cys is a strong nucleophile, the most readily oxidized and nitrosylated in amino acid chain. This consideration suggests that Cys residues may regulate the change of conformation and the activity of hHSF1 through a redox-dependent thiol/disulfide exchange reaction. We want to construct role of five Cys residues of hHSF by redox reagents. According to two studies, Cys residues are related to trimer formation of hHSF1. In this study, we want to demonstrate the correlation between structural change and DNA-binding activity of HSF1 through forming disulfide bond and trimerization. In this results, we could deduce that DNA binding activity of DNA binding domain wasn't affected by redox for always expose outside to easily bind to DNA. DNA binding activity of wild-type HSF's DNA binding domain was affected by conformational change, as conformational structure change (trimerization) caused DNA binding domain.

Dynamic response of segment lining due to train-induced vibration (세그먼트 라이닝의 열차 진동하중에 대한 동적 응답특성)

  • Gyeong-Ju Yi;Ki-Il Song
    • Journal of Korean Tunnelling and Underground Space Association
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    • v.25 no.4
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    • pp.305-330
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    • 2023
  • Unlike NATM tunnels, Shield TBM tunnels have split linings. Therefore, the stress distribution of the lining is different even if the lining is under the same load. Representative methods for analyzing the stress generated in lining in Shield TBM tunnels include Non-joint Mode that does not consider connections and a 2-ring beam-spring model that considers ring-to-ring joints and segment connections. This study is an analysis method by Break-joint Mode. However, we do not consider the structural role of segment lining connections. The effectiveness of the modeling is verified by analyzing behavioral characteristics against vibration loads by modeling with segment connection interfaces to which vertical stiffness and shear stiffness, which are friction components, are applied. Unlike the Non-joint mode, where the greatest stress occurs on the crown for static loads such as earth pressure, the stress distribution caused by contact between segment lining and friction stiffness produced the smallest stress in the crown key segment where segment connections were concentrated. The stress distribution was clearly distinguished based on segment connections. The results of static analysis by earth pressure, etc., produced up to seven times the stress generated in Non-joint mode compared to the stress generated by Break-joint Mode. This result is consistent with the stress distribution pattern of the 2-ring beam-spring model. However, as for the stress value for the train vibration load, the stress of Break-joint Mode was greater than that of Non-joint mode. This is a different result from the static mechanics concept that a segment ring consisting of a combination of short members is integrated in the circumferential direction, resulting in a smaller stress than Non-joint mode with a relatively longer member length.

Nonlinear Lateral Behavior and Cross-Sectional Stress Distribution of Concrete Rocking Columns (콘크리트 회전형 기둥의 비선형 횡방향 거동 및 단면응력 분포 분석)

  • Roh, Hwa-Sung;Hwang, Woong-Ik;Lee, Hu-Seok;Lee, Jong-Seh
    • Journal of the Korea Concrete Institute
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    • v.24 no.3
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    • pp.285-292
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    • 2012
  • Fixed connection is generally used for beam and column connections of concrete structures, but significant damages at the connection due to severe earthquakes have been reported. In order to reduce damages of the connection and improve seismic performance of the connection, several innovative connections have been suggested. One newly proposed connection type allows a rotation of the connection for applications in rotating or rocking beams, columns, and shear walls. Such structural elements would provide a nonlinear lateral force-displacement response since their contact depth developed during rotation is gradually reduced and the stress across the sections of the elements is non-linearly distributed around a contact area, which is called an elastic hinge region in the present study. The purpose of the present study is to define the elastic hinge region or length for the rocking columns, through investigating the cross-sectional stress distribution during their lateral behavior. Performing a finite element analysis (FEA), several parameters are considered including axial load levels (5% and 10% of nominal strength), different boundary conditions (confined-ends and cantilever types), and slenderness ratios (length/depth = 5, 7, 10). The FEA results showed that the elastic hinge length does not directly depend on the parameters considered, but it is governed by a contact depth only. The elastic hinge length started to develop after an opening state and increased non-linearly until a rocking point(pre-rocking). However, the length did not increase any more after the rocking point (post-rocking) and remained as a constant value. Half space model predicting the elastic hinge length is adapted and the results are compared with the numerical results.

Effects of Elevated CO2 Concentration on Leaf Phenology of Quercus acutissima (이산화탄소 농도 증가가 상수리나무 잎의 계절현상에 미치는 영향)

  • Seo, Dong-Jin;Oh, Chang-Young;Han, Sim-Hee;Lee, Jae-Cheon
    • Korean Journal of Agricultural and Forest Meteorology
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    • v.16 no.3
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    • pp.213-218
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    • 2014
  • Effects of elevated $CO_2$ on leaf phenology of Quercus acutissima were examined using open-top chambers, which had ambient and elevated $CO_2$ concentrations (ambient ${\times}1.4$, ambient ${\times}1.8$). To analyze the effect of chamber, non-treatment block was established near outside of the chambers. In 2013, budburst, leaf unfolding, coloring, and shedding were surveyed, and spring phenology was surveyed in 2014. Thermal sum (base temperature $+5^{\circ}C$) of each phenological event occurred was recorded. In addition, bud samples were collected and analyzed for carbohydrate contents in March 2014. Elevated $CO_2$ concentration advanced budburst and leaf unfolding, and delayed shedding in 2013. However, in 2014, the temperature of the spring season was high, and there was no significant effect of elevated $CO_2$ concentration on spring phenology. Carbohydrates content, such as starch, total non-structural carbohydrate and total soluble sugar, were significantly increased in response to elevated $CO_2$ concentration. It has been proposed that elevated $CO_2$ concentration could extend the growing season of temperate species with increased possibility of frost damage due to early bud opening and leaf unfolding. However, our analysis showed that the increased carbohydrate concentration in bud under elevated $CO_2$ would reduce the possibility of early spring frost damage by acting as cryoprotectant.

FMDV 2C Protein of Foot-and-mouth Disease Virus Increases Expression of Pro-inflammatory Cytokine TNFα via Endoplasmic Reticulum Stress (구제역바이러스의 FMDV 2C 단백질은 소포체 스트레스를 통해서 염증 유도 사이토카인 TNFα의 발현을 증가시킴)

  • Kang, Hyo Rin;Seong, Mi So;Nah, Jin Ju;Ryoo, Soyoon;Ku, Bok Kyung;Cheong, JaeHun
    • Journal of Life Science
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    • v.30 no.3
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    • pp.285-290
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    • 2020
  • Foot-and-mouth disease virus (FMDV), a member of the genus Aphthovirus in the Picornaviridae family, affects wild and domesticated ruminants and pigs. FMDV causes various clinical symptoms, including severe inflammation in infected tissue. Genome RNA of FMDV shows a positive single-strand chain approximately 8.3 kb long and encodes a single long open reading frame (ORF). The ORF is translated into structural and non-structural proteins by viral proteases. The FMDV 2C protein is one of the non-structural proteins encoded by FMDV and plays a critical role in FMD pathogenesis, including inflammation, apoptosis, and viral replication. In this study, we examined whether FMDV 2C induces intracellular expression of pro-inflammatory cytokine tumor necrosis factor alpha (TNFα). FMDV 2C expression in pig IBRS-2 cells increased mRNA and protein expression of TNFα at the transcriptional level via activation of TNFα promoter. Treatment with 4-phenylbutyric acid, an endoplasmic reticulum (ER) stress reducer, decreased TNFα expression induced by FMDV 2C. Activating transcription factor 4 (ATF4), a transcription factor mediating ER stress response, induced transactivation of TNFα promoter and expression of mRNA and protein of TNFα. However, the dominant negative mutant of ATF4 did not induce FMDV 2C-mediated TNFα expression. The results indicate that FMDV 2C protein increases clinical inflammation via ATF4-mediated TNFα expression and is associated with ER stress induction.

Comparison of Non-structural Carbohydrate Concentration Between Zoysiagrass and Creeping Bentgrass During Summer Growing Season (하계 생육기 동안 Zoysiagrass와 Creeping Bentgrass의 비구조적 탄수화물 함량의 비교)

  • Kim, Dae-Hyun;Jung, Woo-Jin;Lee, Bok-Rye;Kim, Kil-Yong;Kim, Tae-Hwan
    • Journal of The Korean Society of Grassland and Forage Science
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    • v.22 no.2
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    • pp.145-152
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    • 2002
  • To compare the Carbon metabolic response to high temperature stress in Zoysiagrass [Zoysia matrella (L.) Merr.] and Creeping bentgrass (Agrostis palustris Huds) with respect to heat tolerance, C metabolites were determined from April to September. Sampling was carried out on an established golf course (Muan Country Club, Chonnam, Korea). Shoot mass(g Dry weight per hole cup) of creeping bentgrass started to decrease from June and recovered from August whereas that of zoysiagrass was less varied. Chlorophyll content in creeping bentgrass was significantly higher than zoysiagrass until July, and then decreased by 43% from July to August. Zoysiagrass contained higher soluble sugar than creeping bentgrass throughout experimental period. Soluble sugar in zoysiagrass increased about 58% from April to May, and less varied until August. Soluble sugar in creeping bentgrass slightly increased until July and sharply decreased at August. Starch concentration in zoysiagrass continuously decreased to September after a significant increase from April to May. A remarkable fluctuation in both starch and fluctuation concentration was observed between June and August showing high accumulation for June to July and high degradation for July to August. These results suggest that through creeping bentgrass suffers much severely from high temperature stress than zoysiagrass especially June to August. An active accumulation and degradation in nonstructural carbohydrate in creeping bentgrass during this period might be associated with heat stress.

Seismic Fragility Evaluation of Cabinet Panel by Nonlinear Time History Analysis (비선형시간이력해석을 이용한 수배전반의 지진취약도 도출)

  • Moon, Jong-Yoon;Kwon, Min-ho;Kim, Jin-Sup;Lim, Jeong-Hee
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.19 no.2
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    • pp.50-55
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    • 2018
  • Earthquakes are almost impossible to predict and take place in a short time. In addition, there is little time to take aggressive action when an earthquake occurs. Therefore, there are more casualties and property damage than with other natural disasters. Recently, earthquakes have been occurring all over the world. As the number of earthquakes increase, studies on the safety of structures are being carried out. On the other hand, there are few studies on the electric facilities, which are relatively non - structural factors. Currently, electrical equipment in Korea is often not designed for earthquake safety and is quite vulnerable to damage when an earthquake occurs. Therefore, in this study, modeling was conducted through ABAQUS similar to an actual cabinet panel and 3D dynamic nonlinear analysis was performed using a natural seismic. According to seismic zone I and normal ground rock conditions of the power transmission and transmission facility seismic design practical guide, the maximum response acceleration of the performance level was 0.157g. In this study, however, it was not safe to reach the limit state of 30% of the analytical result at 0.1g for the general cabinet panel. From the results, the seismic fragility curve was derived and analyzed. The derived seismic fragility curve is presented as a quantitative basis for determining the limit state of the cabinet panel and can be utilized as basic data in related research.

Implementation and Evaluation of a Web Ontology Storage based on Relation Analysis of OWL Elements and Query Patterns (OWL 요소와 질의 패턴에 대한 관계 분석에 웹 온톨로지 저장소의 구현 및 평가)

  • Jeong, Dong-Won;Choi, Myoung-Hoi;Jeong, Young-Sik;Han, Sung-Kook
    • Journal of KIISE:Databases
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    • v.35 no.3
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    • pp.231-242
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    • 2008
  • W3C has selected OWL as a standard for Web ontology description and a necessity of research on storage models that can store OWL ontologies effectively has been issued. Until now, relational model-based storage systems such as Jena, Sesame, and DLDB, have been developed, but there still remain several issues. Especially, they lead inefficient query processing performance. The structural problems of their low query processing performance are as follow: Jena has a simple structure which is not normalized and also stores most information in a single table. It exponentially decreases the performance because of comparison with unnecessary information for processing queries requiring join operations as well as simple search. The structures of storages(e.g., Sesame) have been completely normalized. Therefore it executes many join operations for query processing. The storages require many join operations to find simply a specific class. This paper proposes a storage model to resolve the problems that the query processing performance is decreased because of non-normalization or complete normalization of the existing storages. To achieve this goal, we analyze the problems of existing storage models as well as relations of OWL elements and query patterns. The proposed model, defined with the analysis results, provides an optimal normalized structure to minimize join operations or unnecessary information comparison. For the experiment of query processing performance, a LUBM data sets are used and query patterns are defined considering search targets and their hierarchical relations. In addition, this paper conducts experiments on correctness and completeness of query results to verify data loss of the proposed model, and the results are described. With the comparative evaluation results, our proposal showed a better performance than the existing storage models.

Behavioral Change of Workers who completed Experiential Safety Training (체험식 안전교육 이수 근로자의 행동 변화 연구)

  • Choonhwan, Cho
    • Journal of the Society of Disaster Information
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    • v.19 no.1
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    • pp.161-172
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    • 2023
  • Safety education delivered to construction workers in a lecture manner has limitations in concentration and immersion, so delivery power and interest are low. In order to improve unstable behavior through education and prevent safety accidents, it is necessary to change the paradigm to hands-on education. Purpose: Experiential safety education aims to contribute to preventing accidents for construction workers by quickly recognizing risks, improving emergency response skills, and verifying the effectiveness of pre- and post-learning. Method: Based on a survey of workers who experienced the same work environment as the actual construction site, an opinion survey on the pre- and post-safety experience education and a variable measurement tool were planned, and a research hypothesis was established. Results: The Bayesian theory and MC simulation analysis were used to analyze the structural equation model, and the change in construction worker behavior was confirmed through the intended safety (A), non-experiential education in the sub-area of anxiety (B), average, standard deviation, and minimum and maximum values. Conclusion: The effect of education and industrial accidents are reduced only when construction workers are motivated to participate.