• Title/Summary/Keyword: structural adaptation

Search Result 217, Processing Time 0.032 seconds

Increase of Synapsin I, Phosphosynapsin (ser-9), and GAP-43 in the Rat Hippocampus after Middle Cerebral Artery Occlusion

  • Jung, Yeon-Joo;Huh, Pil-Woo;Park, Su-Jin;Park, Jung-Sun;Lee, Kyung-Eun
    • The Korean Journal of Physiology and Pharmacology
    • /
    • v.8 no.2
    • /
    • pp.77-81
    • /
    • 2004
  • The loss of neurons and synaptic contacts following cerebral ischemia may lead to a synaptic plastic modification, which may contribute to the functional recovery after a brain lesion. Using synapsin I and GAP-43 as markers, we investigated the neuronal cell death and the synaptic plastic modification in the rat hippocampus of a middle cerebral artery occlusion (MCAO) model. Cresyl violet staining revealed that neuronal cell damage occurred after 2 h of MCAO, which progressed during reperfusion for 2 weeks. The immunoreactivity of synapsin I and GAP-43 was increased in the stratum lucidum in the CA3 subfield as well as in the inner and outer molecular layers of dentate gyrus in the hippocampus at reperfusion for 2 weeks. The immunoreactivity of phosphosynapsin was increased in the stratum lucidum in the CA3 subfield during reperfusion for 1 week. Our data suggest that the increase in the synapsin I and GAP-43 immunoreactivity probably mediates either the functional adaptation of the neurons through reactive synaptogenesis from the pre-existing presynaptic nerve terminals or the structural remodeling of their axonal connections in the areas with ischemic loss of target cells. Furthermore, phosphosynapsin may play some role in the synaptic plastic adaptations before or during reactive synaptogenesis after the MCAO.

A Study on the Factors of Using Intention of U-City Services for the Disabled to Reduce Ubiquitous Divide (유비쿼터스격차 해소를 위한 장애인의 U-City 서비스 사용의도에 영향을 미치는 요인에 관한 연구)

  • Lee, Mi-Gyeong;Kang, Ju-Young;Lee, Sang-Gun
    • The Journal of Information Systems
    • /
    • v.17 no.2
    • /
    • pp.95-112
    • /
    • 2008
  • The development of the Information Technology(IT) has brought enormous change to the human life, not even only to the politics, economy, society, and cultures, but all the way through the people's consciousness and cultural patterns. However, the information society resulted information inequality issues and especially to those disabled people, who have more difficulties on the technology adaptation, the "digital divide" symptom is significantly found. At present the rapid development of IT has gone beyond the level of the information society and it is accelerating the ubiquitous society that will combine people, computers, and all objects into one. And during the time of ubiquitous the "digital divide" will still exist. This research is focused on the digital divide of disabled people that were insufficiently covered in the research of digital divide and ubiquitous. From the empirical study of the effect that the disabled contributes on the service usability in U-City, the factors of background of the digital divide, and the difference of such factors in types of sex, ages, disabled types, and disabled class, and finally how the ubiquitous divide of the disabled affects have been researched. Based on the proposed study model and by analyzing the model by structural equation, following resulted was gained. (1) With the TAM (TAM : Technology Acceptance Model), which is commonly used in the studies of IT devices and services, the digital divide of the disabled cases cannot be identified sufficiently since it is not eligible for Using Intention of U-City Services. (2) In case of the disabled, the mental factors like willingness to overcome the impediment and accessibility like environment to meet the information services and ability to access the services are more effective on Using Intention of U-City Services rather than TAM.

Multi-Objective Optimization of Flexible Wing using Multidisciplinary Design Optimization System of Aero-Non Linear Structure Interaction based on Support Vector Regression (Support Vector Regression 기반 공력-비선형 구조해석 연계시스템을 이용한 유연날개 다목적 최적화)

  • Choi, Won;Park, Chan-Woo;Jung, Sung-Ki;Park, Hyun-Bum
    • Journal of the Korean Society for Aeronautical & Space Sciences
    • /
    • v.43 no.7
    • /
    • pp.601-608
    • /
    • 2015
  • The static aeroelastic analysis and optimization of flexible wings are conducted for steady state conditions while both aerodynamic and structural parameters can be used as optimization variables. The system of multidisciplinary design optimization as a robust methodology to couple commercial codes for a static aeroelastic optimization purpose to yield a convenient adaptation to engineering applications is developed. Aspect ratio, taper ratio, sweepback angle are chosen as optimization variables and the skin thickness of the wing. The real-coded adaptive range multi-objective genetic algorithm code, which represents the global multi-objective optimization algorithm, was used to control the optimization process. The support vector regression(SVR) is applied for optimization, in order to reduce the time of computation. For this multi-objective design optimization problem, numerical results show that several useful Pareto optimal designs exist for the flexible wing.

Partitioning of Carbon and Nitrogen Reserves During Winter Adaptation and Spring Regrowth II. Effect of seeding density on the content of organic reserves on the wintering period and forage yeild in rape ( Brassica napus L. ) (저장탄수화물과 질소의 월동성과 재생활력에 대한 이용성 II. 추파 유채 ( Brassica napus L. ) 의 파종밀도가 월동중 저장유기물 함량 및 수량에 미치는 영향)

  • 김태환;김기원;정우진;전해열;김병호
    • Journal of The Korean Society of Grassland and Forage Science
    • /
    • v.15 no.4
    • /
    • pp.231-237
    • /
    • 1995
  • The objective of this study is to obtain the basic data for investigating the effects of organic reserves on winter survival or regrowth yield. Forage rape (Brassica napus L.) was sown by three seeding densities of 5, 15 and 25cm interval among plants on Sep. 1, 1994. Field-grown plants were sampled on the before wintering (Dec. 4) and on the wintering period (Jan. 16) to analyze the nitrogen and non-structural cahohydrate reserves. The rate of winter survival and regrowth yield were also measured in the spring of next year. The dry matter yields from the plots of 5, 15 and 25cm seeding interval were 1,270, 1.01 9 and 1,062 kg/lOa respectively, on the before wintering. The similar pattern wa5 observed in the crude protein yields affected by seeding density. On the before wintering, both of nitrogen and starch contents per plant significantly increased as the seeding density was lowered. Starch content was relatively higher than that of nitrogen in all plots. On the wintering period, the contents of nitrogen reserves were 6.5, 41.2 and 121.7 mglplant, those of starch reserves were 1.0, 5.4 and 185.1 mg/plant, respectively, in the plots of 5, 15 and 25cm seeding interval. Nitrogen reserves on the wintering period increased while starch reserves highly decreased in all plots comparing to the before wintering. 'lhe rates of winter survival were 10.2, 20.6 and 37.1%, and regrowth yields were 76, 96 and 178 kgD.M/ IOa, respectively, in the plots of 5, 15 and 25cm seeding interval. These results cleariy showed that seeding density have a close influence on the level of nitrogen and non-structurd cahohydrate reserves, and that the rate of winter survival and regrowth yield were controlled by reserves level on the wintering period.

  • PDF

( Partitioning of Carbon and Nitrogen Reserves During Winter Adaptation and Spring Regrowth III. Effect of cutting date on the content of organic reserves on the wintering period and forage yeild in rape( Brassica napus L. ) (저장탄수화물과 질소의 월동성과 재생활력에 대한 이용성 III. 추파 유채 ( Brassica napus L. ) 의 예취기시가 월동중 저장유기물 함량 및 수량에 미치는 영향)

  • 김태환;김기원;정우진;전해열;김병호
    • Journal of The Korean Society of Grassland and Forage Science
    • /
    • v.15 no.4
    • /
    • pp.238-244
    • /
    • 1995
  • The objective of this study is to obtain the basic data for investigating the effects of organic reserves on winter survial or regrowth yield. Forage rape(Brassica napus L.) was sown on Sep. 1, 1994. Experimental plots were divided into three replicates under 6 different cutting dates(l0 days interval from Oct. 15 to Dec. 4). Field-grown palnts were sampled on the each cutting date and on the wintering period (Jan. 16) to analyze the nitrogen and non-structural cahohydrate reserves. The rate of winter survival and regrowth yield were also measured in the spring of next year. On the before wintering, dry matter yields were 152, 274, 500, 718, 776 and 981 kg/lOa, respectively, from the cutting date on Oct. 15, Oct. 25, Nov. 4, Nov. 14, Nov. 24, and Dec. 4. Cmde protein yield significantly increased as cutting date was later until Nov. 14, thereafter a significant increase did not occured. Nitrogen and starch contents per plant significnatly increased as the cutting date was later. The increasing rate of starch was greatly higher than that of nitrogen. On the wintering period, nitrogen reserves in mts were 85.3, 68.8, 47.6, 28.3, 44.3, and 55.3 mglplant, and starch reserve were 11 1.3, 75.3, 39.3, 19.6, 26.4 and 34.6 mglplant, respectively, in the plots cut on Oct. 15, Oct. 25, Nov. 4, Nov. 14, Nov. 24, and Dec. 4. It showed that carbohydrate reserves were much highly utilized than nitrogen reserves during wintering period. The rates of winter survival were 91, 83, 46, 22, 35 and 43% and regrowth yields were 692, 545, 316, 84, 127 and 140 kgD.M/lOa, respectively, in each plots. The highly significant correlation (p<0.01) between the level of organic reserves and the rate of winter survival or regrowth yield were obtained.

  • PDF

( Partitioning of Carbon and Nitrogen Reserves During Winter Adaptation and Spring Regrowth IV. Effect of seeding date on the content of organic reserves on the wintering period and forage yeild in rape ( Brassica napus L. ) (저장탄수화물과 질소의 월동성과 재생활력에 대한 이용성 IV. 추파 유채 ( Brassica napus L. ) 의 파종시기가 월동중 저장유기물 함량 및 수량에 미치는 영향)

  • 김태환;김기원;정우진;전해열;김병호
    • Journal of The Korean Society of Grassland and Forage Science
    • /
    • v.16 no.1
    • /
    • pp.1-8
    • /
    • 1996
  • The objective of this study is to obtain the basic data for investigating the effects of organic reserves on winter survial or regrowth yield. Forage rape (Brussicu napus L.) was sown at 10 day> interval from Sep. I to Nov. 1. Field-grown palnts were sampled on the before wintering (Dec. 4) and on the wintering period (Jan. 16) to analyze the nitrogen and non-structural cahohydrate reserves. The rate of winter survival and regrowth yield were also measured in the spring of next year. On the before wintering, the dry matter yields from the plots sown on Sep. 1, Sep.11 and Sep. 21 were 860, 596 and 260 kg/lOa, respectively. No. harvest was canied out on the plots sown after Oct. 1 because the growth state was not enough to cut. Both of nitrogen and starch contents per plant significantly increased as the seeding date was later. On the wintering period, the contents of nitrogen reserves in roots were 176.8. 120.1, 71.7, 84.0, 72.1, 45.3 and 33.3 mg/plant, those of starch reserves were 199.0. 55.8, 21.8, 92.6, 86.5, 36.4 and 29.0 mglplant, resepctively, in the plots sown on Sep. 1, Sep. 11, Sep. 21, Oct. I, Oct. 11, Oct. 21 and Nov. 1. The rates of winter survival were 40, 36, 33, 85, 87, 59 and 49% and regrowth yields were 161, 86, 65, 520, 451, 121 and 33 kgD.M/lOa, respectively, in each plots. 'Ihese results clearly showed that seeding date has a close influence on the level of organic reserves and forage yield, and that the possibility of continuous utilization on the before and alter wintering is extremely limited by seeding date.

  • PDF

A Development of Tentative Measuring items of Korean Corporate Symbolic Image using brand personality (브랜드 개성 항목을 활용한 한국 기업의 상징적 이미지 측정 도구 시안 개발)

  • Oh, Ju-Yeon;Kim, Young-Kyun
    • Journal of Korea Society of Industrial Information Systems
    • /
    • v.17 no.3
    • /
    • pp.83-94
    • /
    • 2012
  • This study was designed to identify and develop the measurement items of symbolic image (personality) of most preferred Korean companies in adaptation of prior research of brand personality. From the common factor analysis, factors were extracted to five dimensions: Sincerity, Competence, Affection, Excitement, and Sophistication. In this survey, we collected data from the 558 respondents and performed a structural equation model using AMOS 16.0. The result of the confirmatory factor analysis indicated that the measurement model of Korean corporate symbolic image could be effectively used to envision the personality of Korean companies with similar context of brand personality research. Furthermore, this empirical study showed interesting results. One of unique Korean emotions, affection factor, was derived from this research as well and it is also proven that the Korean-corporate symbolic image could be used to measure the corporate personality and it should be continuously reinterpreted with deviation of socio-cultural changes rather than adhering to standardized paradigm.

Examining the Influence of Entrepreneurship on Innovation Activities and Performance with the Mediating Role of Technological Innovation (기업가 정신이 기술혁신과 혁신성과에 미치는 영향 및 기술혁신의 매개역할)

  • Ju, Ki-Jung;Park, Byeonghwa
    • Management & Information Systems Review
    • /
    • v.34 no.2
    • /
    • pp.21-37
    • /
    • 2015
  • Entrepreneurship and innovation are highlighted as a way to overcome limitations and risk factors caused by today's uncertain business environment. As the uncertainty in the business environment increases, organizations are required to adapt to ever changing business dynamics. For this adaptation, entrepreneurship and innovation are crucial factors. This study proposes a model to explain a structural relationship between entrepreneurship, technological innovation, and innovation performance. The unit of analysis focus is small and medium-sized businesses. Empirical results show that there are positive causal relationships from entrepreneurship to technological innovation, and from technological innovation to innovation performance. Additionally, no direct relationship from entrepreneurship to innovation performance can be achieved through innovation activities such as technological innovation. This study points out the importance of entrepreneurship and technological innovation, and suggests that entrepreneurship along with technological innovation should be internalized as business practices leading to increased performance.

  • PDF

Acute Changes in Fascicle Behavior and Electromyographic Activity of the Medial Gastrocnemius during Walking in High Heeled Shoes

  • Kim, Jin-Sun;Lee, Hae-Dong
    • Korean Journal of Applied Biomechanics
    • /
    • v.26 no.1
    • /
    • pp.135-142
    • /
    • 2016
  • Objective: The purpose of this study was to investigate the acute effect of walking on high heels on the behavior of fascicle length and activation of the lower limb muscles. Methods: Twelve healthy inexperienced high heel wearers (age: $23.1{\pm}2.0yr$, height: $162.4{\pm}4.9cm$, weight: $54.4{\pm}8.5kg$) participated in this study. They walked in high heels (7 cm) and barefoot on a treadmill at their preferred speed. During the gait analysis, the lower limb joint kinematics were obtained using a motion analysis system. In addition, the changes in fascicle length and the level of activation of the medial gastrocnemius (MG) were simultaneously monitored using a real-time ultrasound imaging technique and surface electromyography, respectively. Results: The results of this study show that the MG fascicle operates at a significantly shorter length in high heel walking ($37.64{\pm}8.59mm$ to $43.99{\pm}8.66mm$) in comparison with barefoot walking ($48.26{\pm}9.02mm$ to $53.99{\pm}8.54mm$) (p < .05). In addition, the MG fascicle underwent lengthening during high heel walking with relatively low muscle activation while it remained isometric during barefoot walking with relatively high muscle activation. Conclusion: Wearing high heels alters the operating range of the MG fascicle length and the pattern of muscle activation, suggesting that prolonged wearing of high heels might induce structural alterations of the MG that, in turn, hinder normal functioning of the MG muscle during walking.

Validating the Entrepreneurial Intention Model on the University Students in Saudi Arabia

  • HODA, Najmul;AHMAD, Naim;AHMAD, Mobin;KINSARA, Abdullah;MUSHTAQ, Afnan T.;HAKEEM, Mohammad;AL-HAKAMI, Mwafaq
    • The Journal of Asian Finance, Economics and Business
    • /
    • v.7 no.11
    • /
    • pp.469-477
    • /
    • 2020
  • The main objective of this paper is to examine the applicability of Linan and Chen's entrepreneurial intention model (EIM) in predicting the entrepreneurial intention. EIM is an adaptation of the Theory of Planned Behavior that focuses on entrepreneurial intention and hypothesizing slightly different patterns of relationship with regards to subjective norms. The model also includes human capital and demographic factors. Snowball sampling method was used to collect data using the entrepreneurial intention questionnaire (EIQ) through several social media platforms. The survey indicates that the overall entrepreneurial intention of Saudi students is high (mean = 5.41). Eight out of the seventeen hypothesized relationships were found to be significant. Among the demographic variables, gender-personal attitude was significant whereas self employment experience and years of business education were found to be significantly related with perceived behavioral control. The statistical analysis using partial least square structural equation modelling validated the model. All the three antecedents of entrepreneurial intention were significantly related with entrepreneurial intention. The results of this study will help policy makers to get deep understanding into the phenomenon of entrepreneurship among Saudi university students and thereby develop a conducive environment. This study also validates the entrepreneurial intention model in a different cultural context.