• 제목/요약/키워드: strong unit

검색결과 489건 처리시간 0.029초

뽕나무에서 추출한 단백질 분해호소의 특성 (The Properties of Proteolytic Enzymes from the Mulberry (Morus alba L.))

  • 윤숙자;오성훈;장명숙
    • 한국식품조리과학회지
    • /
    • 제13권5호
    • /
    • pp.623-626
    • /
    • 1997
  • 뽕나무는 옛날 가정에서 질긴 쇠고기를 조리할 때 사용하였다고 하였는데, 실제로 육류 조리에의 이용 가능성을 모색하기 위하여 우선 뽕나무 줄기의 속껍질에서 추출한 단백질 분해효소의 활성 및 특성을 알아 본 결과는 다음과 같다. 시료 2,800 g으로부터 조효소 분말 2.25 g을 회수하였는데, 회수율은 0.08% (wet basis)이었다. 뽕나무에서 추출한 단백질 분해효소 활성은 2,358 unit/g을 나타내었다. 효소의 특성 중 기질 특이성은 다른 단백질 기질에 대한 뽕나무에서 추출한 조효소의 효소활성을 조사해 본 결과 casein 100에 대하여 hemoglobin 44, collagen 34, egg white 20, gelatin 13의 비율로 가수분해하는 것으로 나타났다. 이 결과 뽕나무에서 추출한 조효소의 기질 특이성은 육류에 주로 함유된 단백질인 hemoglobin과 collagen을 비교적 잘 가수분해하는 것으로 나타났다. 뽕나무에서 추출한 조효소의 활성 온도는 30~6$0^{\circ}C$였고, 최적온도는 5$0^{\circ}C$로 나타났으며, 7$0^{\circ}C$ 이상의 온도에서는 그 활성이 급격히 감소하였다. 또한 pH를 달리한 역가 실험은 pH 5.0~7.0에서 안정하였고, 최적 pH는 6.0으로 관찰되어졌으며 8.0이상의 pH에서는 그 활성이 급격히 떨어졌다. 또한 뽕나무에서 추출한 조효소의 단백질 함량은 7.2%였고, specific activity는 32.75 unit/mg이었다.

  • PDF

기존한약서의 현대적 용량 환산을 위한 도량형의 시대적 변천 고찰 (Historical Changes in Weights and Measures of Herbal Formulas in Medical Classics)

  • 한천희;이수연;김지훈;김윤경
    • 대한한의학방제학회지
    • /
    • 제25권1호
    • /
    • pp.103-113
    • /
    • 2017
  • Objectives : Korea and China are applying different conversion standards for weight in traditional medicine books. This study aims to research and suggest how to convert the units of weight in old traditional medicine classics into the contemporary unit of grams. Methods : Historical documents of Korea and China were used to review the process in which weights and measures changed in each country and the manners in which the Chinese units of weight were introduced to Korea. Results : Weights and measures changed with time. They became almost standardized by the period of Song in China, when coins played the most crucial role, and it was introduced to Korea. Donggaryang, the standard container for weights and measures in ancient China, Gaewontongbo, a coin in Tang, Sangpyeongtongbo, a coin in Joseon, and a scale in Joseon were used as strong foundations for conclusion from literature review. Weight of a 1-don(coin) in the time a traditional medicine books were written was used as a unit of weight in those books. Sangpyeongtongbo, a 1-don coin in Joseon, weighs 4 grams on average. Conclusions : Since the current conversion of 1-don coin into 3.75 grams is not supported by literature review, it is suggested that 1-don(coin) as a unit of weight in traditional medicine books of Joseon, may be better converted into 4 grams, while that of China is converted to 3.73 grams.

분산 네트워크 환경하에서 TMO를 이용한 중환자 생체정보 원격 진료 시스템 구현 (The Implementation of Patient Vital Sign Information Telemedicine System using TMO in Distributed Network Enviroment)

  • 김광준
    • 한국정보통신학회논문지
    • /
    • 제13권6호
    • /
    • pp.1128-1140
    • /
    • 2009
  • 본 논문에서는 TMO 실시간 객체 모델을 이용하여 실시간 통신 메시지 서비스를 효과적으로 지원하기 위해 중환자의 실시간 생체정보 전송 시스템을 나타내었다. 또한 분산된 네트워크 시스템에서 TMO 구조를 이용하여 ICU(intensive care unit) 응용 환경에 적용함으로서 실시간 메시지 서비스를 보장하였다. TMO를 이용한 생체정보 파싱 수신 모듈은 ICU의 Central Monitor로부터 수신할 수 있는 Raw Data 형태의 환자의 생체 정보를 생체 정보 웹 뷰어 시스템에서 사용가능한 데이터로 분석할 수 있도록 설계하였다. 실시간 뷰어 시스템은 환자 생체정보에 대한 실시간성과 생체 정보에 대한 데이터의 연속성을 부여하여 베드 사이트의 환자에게서 발생된 모든 생체정보에 의해 환자 관리를 데이터베이스를 이용하여 전산화함으로써 환자의 광범위한 자료 검색이 이루어지므로 원격진료로 활용이 가능하다. TMO 객체 모델을 기반으로 한 실시간 시뮬레이션에서 몇 가지의 TMO 구조의 장점을 가지고 있으며, TMO 객체 모델은 요구 명세서와 설계 사이의 강력한 연관성을 가지고 있다.

형태소 및 구문 모호성 축소를 위한 구문단위 형태소의 이용 (Using Syntactic Unit of Morpheme for Reducing Morphological and Syntactic Ambiguity)

  • 황이규;이현영;이용석
    • 한국정보과학회논문지:소프트웨어및응용
    • /
    • 제27권7호
    • /
    • pp.784-793
    • /
    • 2000
  • 기존의 한국어 형태소 해석은 한국어의 교착어 특성상 다양한 형태론적 모호성을 가진다. 이러한 형태론적 모호성은 많은 구문 모호성을 만들어 내어 올바른 의미를 가지는 파스트리의 선택을 어렵게 한다. 한국어에서 이런 형태론적 모호성의 대부분이 보조용언이나 의존 명사와 관련이 있다. 보조용언이나 의존명사는 주위의 형태소들과 강한 결합 관계를 가지고 있으며, 대부분 자립성이 없는 기능형태소이다. 결합된 형태소들은 문장 내에서 하나의 기능적 역할이나 구문적 역할을 수행한다. 우리는 품사 태깅된 20 만 어절 크기의 말뭉치로부터 이 형태소열을 찾아 이를 3가지 유형으로 분류하였다. 그리고, 이를 구문 형태소로 정의하고 구문 형태소를 구문 분석의 기본 입력 단위로 간주하였다. 본 논문에서는 구문 형태소가 아래와 같은 문제의 해결에 있어서 효율적인 방법임을 제안한다: 1) 형태소 해석의 축소, 2) 구문 해석 도중 불필요한 부분 파스트리의 배제, 3) 구문 모호성의 축소. 마지막으로, 실험 결과를 통해 구문단위 형태소가 형태소 및 구문 모호성을 축소하기 위해 반드시 필요함을 보인다.

  • PDF

천장 브래킷형 모듈러 시스템의 브래킷 길이와 볼트에 따른 내진성능평가 (Seismic Performance Evaluation of the Ceiling Bracket-type Modular System with Various Bracket Lengths and Bolt Types)

  • 곽의신;강창훈;손수덕;이승재
    • 대한건축학회논문집:구조계
    • /
    • 제34권4호
    • /
    • pp.25-33
    • /
    • 2018
  • In regard to modular systems, new methods, as well as middle and high-story unit design ideas, are currently being studied. These studies need to focus on the enhanced stiffness and seismic performance of these connections, and see that the development of fully restrained moment connections can improve the seismic performance. For this reason, this study evaluates the performance of the connections of the ceiling bracket-typed modular system through repeated loading tests and analyses. In order to compare them with these modular units, new unit specimens with the bracket connection being different from that of the traditional modular unit specimens were designed, and the results of repeated loading tests were analyzed. In the traditional units, the structural performances of both welding connection and bolt connection were evaluated. In regard to the testing results, the initial stiffness of the hysteresis curve was compared with the theoretical initial stiffness, and the features of all specimens were also analyzed with regard to the maximum moment. In addition, the test results were examined with regard to the connection flexural strength of the steel special moment frame specified under the construction criteria KBC2016. The connections, which were proposed in the test results, were found to be fully restrained moment connections for designing strong column-weak beams and meeting the requirements of seismic performance of special moment frames.

Sub-Health Status Survey and Influential Factor Analysis in Chinese during Coronavirus Disease 2019 Pandemic

  • Pan, Yanbin;Yan, Jianlong;Lu, Wanxian;Shan, Miaohang
    • 대한간호학회지
    • /
    • 제51권1호
    • /
    • pp.5-14
    • /
    • 2021
  • Purpose: This study aimed to investigate sub-health status (SHS) of people living in China during the Coronavirus disease 2019 (COVID-19) COVID-19 pandemic. COVID-19 is a severe acute respiratory syndrome coronavirus (SARS-CoV) infection-induced acute infectious disease, which is featured by universal susceptibility and strong infectivity, and SHS (a status of low quality health) refers to a status of low-quality health. COVID-19 has gradually developed into a global pandemic, making the public in a high stress situation in physiological, psychological and social states in the short term. Methods: From March 6 to 11, 2020, a large-scale cross-sectional survey was conducted by convenient sampling, and SHS assessment scale was used in the questionnaire. The ordinal logistic regression analysis was used to identify the factors affecting SHS. Results: In this study, 17,078 questionnaires were delivered with 16,820 effective questionnaires collected, and 10,715 subjects (63.7%) were found with SHS, with moderate SHS primarily. Physiological sub-scale scored the highest, followed by psychological and social sub-scales. Ordinal logistic regression analysis indicated that man, only-child, workers and farmers were risk factors of SHS. Protective factors of SHS included living in rural areas and townships, laid-off retirees and education degree. Conclusion: It shows many people in China place in a poor health status during COVID-19 pandemic. It is necessary that relevant departments pay more attention to people with poor health such as men, only-child, urban people, workers and farmers, and groups with high education degree during and after pandemic stabilization.

Experimental Tracheal Replacement: Angiogenesis and Null Apoptosis Promote Stenosis

  • Santibanez-Salgado, J. Alfredo;Sotres-Vega, Avelina;Gaxiola-Gaxiola, Miguel O.;Villalba-Caloca, Jaime;Lozoya, Karen Bobadilla;Zuniga-Ramos, Joaquin A.
    • Journal of Chest Surgery
    • /
    • 제54권3호
    • /
    • pp.191-199
    • /
    • 2021
  • Background: Tracheal replacement is a challenge for thoracic surgeons due to stenosis in the trachea-prosthesis anastomosis. We propose that stenosis occurs due to fibrosis as a result of an abnormal healing process, characterized by an increased expression of wound healing growth factors (vascular endothelial growth factor [VEGF], survivin, and CD31), which promote angiogenesis and decrease apoptosis. We analyzed the immunoreactivity of VEGF, survivin, CD31, and caspase-3 in the development of fibrotic stenosis in prosthetic tracheal replacement. Methods: Fourteen dogs were operated on: group I (n=7) received a 6-ring cervical tracheal segment autograft, while in group II (n=7), a 6-ring segment of the cervical trachea was resected and tracheal continuity was restored with a Dacron prosthesis. The follow-up was 3 months. Immunoreactivity studies for VEGF, survivin, CD31, and caspase-3 were performed. A statistical analysis was done using the Wilcoxon signed rank test. Results: Four animals in group I were euthanized on the 10th postoperative day due to autograft necrosis. Three animals completed the study without anastomotic stenosis. Moderate expression of VEGF (p=0.038), survivin (p=0.038), and CD31 (p=0.038) was found. All group II animals developed stenosis in the trachea-prosthesis anastomotic sites. Microscopy showed abundant collagen and neovascularization vessels. Statistically significant immunoreactive expression of VEGF (p=0.015), survivin (p=0.017), and CD31 (p=0.011) was observed. No expression of caspase-3 was found. Conclusion: We found a strong correlation between fibrosis in trachea-prosthesis anastomoses and excessive angiogenesis, moderate to intense VEGF, CD31, and survivin expression, and null apoptotic activity. These factors led to uncontrolled collagen production.

3차원 Unit Cell 모델을 이용한 알루미늄 보레이트 휘스커 강화 Mg 복합재료의 유효 탄성계수 및 계면강도의 분석 (Analysis of Effective Elastic Modulus and Interfacial Bond Strength of Aluminum Borate Whisker Reinforced Mg Matrix Composite by Using Three Dimensional Unit Cell Model)

  • 손재형;이욱진;박용하;박용호;박익민
    • 대한금속재료학회지
    • /
    • 제48권5호
    • /
    • pp.469-475
    • /
    • 2010
  • In this study, the interfacial bond strength of a squeeze infiltrated $Al_{18}B_{4}O_{33}$/AS52 Mg composite was investigated by using a finite element method. Three types of Mg composites with volume fractions of 15, 25 and 35% were fabricated. Three-dimensional models of the composite were developed by using a unit cell model in order to determine the effective elastic modulus of the metal matrix composite and the interfacial bond strength between the whisker and magnesium matrix. After modeling, numerical results were compared with the experimental tensile test results of $Al_{18}B_{4}O_{33}$/AS52 Mg composites. The results showed that the effective modulus of the composite strongly depended on the interfacial strength between the matrix and reinforcement. Based on the numerical and experimental findings, it was found that the strong interfacial bond was achieved by the interfacial reaction product of 30 nm thick MgO, which led to an improvement in the mechanical properties of the $Al_{18}B_{4}O_{33}$/AS52 Mg composites.

Computerized Sunnybrook facial grading scale (SBface) application for facial paralysis evaluation

  • Jirawatnotai, Supasid;Jomkoh, Pojanan;Voravitvet, Tsz Yin;Tirakotai, Wuttipong;Somboonsap, Natthawut
    • Archives of Plastic Surgery
    • /
    • 제48권3호
    • /
    • pp.269-277
    • /
    • 2021
  • Background The Sunnybrook facial grading scale is a comprehensive scale for the evaluation of facial paralysis patients. Its results greatly depend on subjective input. This study aimed to develop and validate an automated Sunnybrook facial grading scale (SBface) to more objectively assess disfigurement due to facial paralysis. Methods An application compatible with iOS version 11.0 and up was developed. The software automatically detected facial features in standardized photographs and generated scores following the Sunnybrook facial grading scale. Photographic data from 30 unilateral facial paralysis patients were randomly sampled for validation. Intrarater reliability was tested by conducting two identical tests at a 2-week interval. Interrater reliability was tested between the software and three facial nerve clinicians. Results A beta version of the SBface application was tested. Intrarater reliability showed excellent congruence between the two tests. Moderate to strong positive correlations were found between the software and an otolaryngologist, including the total scores of the three individual software domains and composite scores. However, 74.4% (29/39) of the subdomain items showed low to zero correlation with the human raters (κ<0.2). The correlations between the human raters showed good congruence for most of the total and composite scores, with 10.3% (4/39) of the subdomain items failing to correspond (κ<0.2). Conclusions The SBface application is efficient and accurate for evaluating the degree of facial paralysis based on the Sunnybrook facial grading scale. However, correlations of the software-derived results with those of human raters are limited by the software algorithm and the raters' inconsistency.

한반도 서남해안 MIS 5e 해안단구의 퇴적층 특성 연구 (Characteristics of Marine Terrace Sediments Formed during the Marine Isotope Stage 5e in the West South Coast of the Korean Peninsula)

  • 양동윤;한민;김진철;임재수;이상헌;김주용
    • 자원환경지질
    • /
    • 제49권6호
    • /
    • pp.417-432
    • /
    • 2016
  • 이번 연구에서는 해남군 이진리 해안단구가 마지막 간빙기 최온난기(Marine Isotope Stage 5e; MIS 5e)에 형성되었음을 최초로 밝힌다. 이는 해발고도 4.8 m에서 8.8 m까지의 단구이며, 4개의 unit로 나누어진다(unit I: 4.8-5.3 m, unit II: 5.3-6.8 m, unit III: 6.8-8.3 m, unit IV: 8.3-8.8 m). 연구대상 퇴적층은 10-30 cm 간격으로 입도분포, 대자율, 함수율 등의 물리특성 분석, 주원소와 미량원소 분석, 점토광물 정량분석 등을 실시하였으며, OSL 연대분석을 통하여 unit II와 III이 MIS 5e에 형성된 것으로 추정하였다. 퇴적층에 포함된 원력들은 주변에 하천이 없는 점으로 미루어 주변 배후 산지에서 바다로 유입된 쇄설물들이 바다에서 마모 작용을 받은 후 재퇴적된 것으로 추정된다. 연대측정 결과, 전반적으로 매우 빠른 퇴적률을 보이는 점은 최온난기(125k; unit II 하위)를 전후한 급격한 해수면 상승과 더불어 강우량 등의 증가로 인해 쇄설물 유입이 증가한 것으로 추정된다. 연구 지역의 점토 광물 비를 현재의 조간대, 황해와 비교한 결과, 연구 지역의 퇴적물은 바다의 영향을 많이 받은 것으로 추정된다. 이 결과는 과거 해수면이 높았던 시기의 수문 활동 및 퇴적 환경을 규명하는데 활용될 수 있을 것으로 보인다.