• Title/Summary/Keyword: strong source

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Lipoxygenase Inhibition and Antioxidative Activity of Flavonoids from Paeonia moutan Seeds

  • Kim, Hyo-Jin;Chung, Shin-Kyo;Park, Sang-won
    • Preventive Nutrition and Food Science
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    • v.3 no.4
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    • pp.315-319
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    • 1998
  • Previously, the methanolic extract of Paeonia moutan seeds was found to potently inhibit soybean lipoxy-genase (SLO). Hence to isolate SLO inhibitor, the defattd methaniolic extract of the seeds was consecutively partitioned wiht ether, ethyl acetate,n-butanol ,adn water. The ether souble fraction showing strong inhibitory activity against SLO was further fractionated into a strongly acidic, a weakly acidic, and a neutral fractions. The strongly acidic components of the ether extract were successively subjected to chromatography on a silica gel, Sephadex LH-20, and preparative HPLC. Four phenolic compounds were isolated , and twio of them showing a strong SLO inhibition activity were identified as luteolin (IC50=2.32$\mu\textrm{g}$/ml) and 5,6,4'-trihydroxy-7,3'- dimethoxylflavone (IC50=0.31$\mu\textrm{g}$/ml) by UV, IR, 1H-& 13C-NMR, and MS spectroscopy. In addition, two flavonoids showed significantly antioxidative activity as strong as that of of $\alpha$-tocopherol (p<0.05) in the autoxidation system of linoleic acid. These results suggest that luteolin and 5,6,4'-trihydroxy-7,3'-dimethoxy-flavone may be used as a potential source of anti-inflammatory agents with antioxidative activity.

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Meteorological Mechanisms Associated with Long-range Transport of Asian Dust Observed at the West Coast of North America in April 2001

  • Song Sang-Keun;Kim Yoo-Keun;Moon Yun-Seob
    • Journal of Korean Society for Atmospheric Environment
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    • v.20 no.E1
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    • pp.1-14
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    • 2004
  • Meteorological mechanisms in association with long-range transport of Asian dust in April 2001 have been investigated using weather maps, satellite images, TOMS and surface $PM_{10}$ data, backward trajectories, plus modeling output results (geopotential heights, horizontal wind vectors, potential temperatures, and streamlines). The results indicated that long -range transport of Asian dust to the west coast of North America was associated with strong westerlies between the Aleutian low and the Pacific high acting as a conveyor belt. Accelerating westerly flows due to cyclogenesis at the source regions over East Asia transported pollution from the continent to the central Pacific. When the system reached the Aleutian Islands, the intensity of troughs and the westerlies were amplified in the North Pacific. Thereafter the winds between the Aleutian Islands and the Pacific Ocean were more intensified from the air flow transport of the conveyor belt. Consequently, the strong wind in the conveyor belt enhanced the dust transport from the Pacific Ocean to the west coast of North America. This was evidenced by $PM_{10}$ concentration (maximum of about $100{\mu}g\;m^{-3}$) observed In California. Further evidence of the dust transport was found through the observation of satellite images, the distribution of TOMS aerosol index, and the analyses of streamlines and backward trajectories.

A Magnetic Stimulator Adopting a Low-Frequency Fly-Back Switching Circuit (저주파 플라이백 스위칭회로를 이용한 고성능 자기자극기)

  • Yi, Jeong-Han;Kim, Hyung-Sik;Hur, Moon-Chang;Kim, Jung-Hoe
    • Journal of Biomedical Engineering Research
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    • v.27 no.6
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    • pp.343-350
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    • 2006
  • Medical magnetic stimulator generates strong magnetic field pulses. Clinical applications of the magnetic pulse are the stimulation of nervous system and the contraction of muscle. The unique source of the strong magnetic pulse is a capacitor-inductor resonator and this inductor generates a strong sinusoidal magnetic pulse by discharging the capacitor with high initial voltage. Continuous muscle contraction needs sequential generation of the magnetic pulses. However, to keep the magnitude of sequential pulses identical, an expensive high-voltage power supply have to support voltage drop of the capacitor between the pulses. A protection circuit between the supply and the resonator is necessary to protect the supply from reverse current caused by capacitor voltage reversal. In this paper, a new circuit structure of the magnetic stimulator adopting a low-frequency fly-back switching is proposed. The new circuit supports sequential pulse generation and allows the reverse current without damage. Performance of the new circuit is examined and a low-cost magnetic stimulator for urinary incontinence therapy is being developed using the presented method.

Near-fault ground motion effects on the nonlinear response of dam-reservoir-foundation systems

  • Bayraktar, Alemdar;Altunisik, Ahmet Can;Sevim, Baris;Kartal, Murat Emre;Turker, Temel
    • Structural Engineering and Mechanics
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    • v.28 no.4
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    • pp.411-442
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    • 2008
  • Ground motions in near source region of large crustal earthquakes are significantly affected by rupture directivity and tectonic fling. These effects are the strongest at longer periods and they can have a significant impact on Engineering Structures. In this paper, it is aimed to determine near-fault ground motion effects on the nonlinear response of dams including dam-reservoir-foundation interaction. Four different types of dam, which are gravity, arch, concrete faced rockfill and clay core rockfill dams, are selected to investigate the near-fault ground motion effects on dam responses. The behavior of reservoir is taken into account by using Lagrangian approach. Strong ground motion records of Duzce (1999), Northridge (1994) and Erzincan (1992) earthquakes are selected for the analyses. Displacements, maximum and minimum principal stresses are determined by using the finite element method. The displacements and principal stresses obtained from the four different dam types subjected to these nearfault strong-ground motions are compared with each other. It is seen from the results that near-fault ground motions have different impacts on the dam types.

Investigation on site conditions for seismic stations in Romania using H/V spectral ratio

  • Pavel, Florin;Vacareanu, Radu
    • Earthquakes and Structures
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    • v.9 no.5
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    • pp.983-997
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    • 2015
  • This research evaluates the soil conditions for seismic stations situated in Romania using the horizontal-to-vertical spectral ratio (HVSR). The strong ground motion database assembled for this study consists of 179 analogue and digital strong ground motion recordings from four intermediate-depth Vrancea seismic events with $M_w{\geq}6.0$. In the first step of the analysis, the influence of the earthquake magnitude and source-to-site distance on the H/V curves is evaluated. Significant influences from both the earthquake magnitude and hypocentral distance are found especially for soil class A sites. Next, a site classification method proposed in the literature is applied for each seismic station and the soil classes are compared with those obtained from borehole data and from the topographic slope method. In addition, the success and error rates of this method are computed and compared with other studies from the literature. A more in-depth analysis of the H/V results is performed using data from seismic stations in Bucharest and a comparison of the free-field and borehole H/V curves is done for three seismic stations. The results show large differences between the free-field and the borehole curves. As a conclusion, the results from this study represent an intermediary step in the evaluation of the soil conditions for seismic stations in Romania and the need to perform more detailed soil classification analysis is highly emphasized.

A Simple Mlodel for Dispersion in the Stable Boundary Layer

  • Sung-Dae Kang;Fuj
    • Journal of Environmental Science International
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    • v.1 no.1
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    • pp.35-43
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    • 1992
  • Handling the emergency problems such as Chemobyl accident require real time prediction of pollutants dispersion. One-point real time sounding at pollutant source and simple model including turbulent-radiation process are very important to predict dispersion at real time. The stability categories obtained by one-dimensional numerical model (including PBL dynamics and radiative process) are good agreement with observational data (Golder, 1972). Therefore, the meteorological parameters (thermal, moisture and momentum fluxes; sensible and latent heat; Monin-Obukhov length and bulk Richardson number; vertical diffusion coefficient and TKE; mixing height) calculated by this model will be useful to understand the structure of stable boundary layer and to handling the emergency problems such as dangerous gasses accident. Especially, this simple model has strong merit for practical dispersion models which require turbulence process but does not takes long time to real predictions. According to the results of this model, the urban area has stronger vertical dispersion and weaker horizontal dispersion than rural area during daytime in summer season. The maximum stability class of urban area and rural area are "A" and "B" at 14 LST, respectively. After 20 LST, both urban and rural area have weak vertical dispersion, but they have strong horizontal dispersion. Generally, the urban area have larger radius of horizontal dispersion than rural area. Considering the resolution and time consuming problems of three dimensional grid model, one-dimensional model with one-point real sounding have strong merit for practical dispersion model.al dispersion model.

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KIGAM Quake: An open platform for seismological data and earthquake research information

  • Moon-Gyo Lee;Youngchai Kim;Hyung-Ik Cho;Han-Saem Kim;Chang-Guk Sun;Yun-Jeong Seong;Il-Young Che
    • Geomechanics and Engineering
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    • v.37 no.3
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    • pp.279-291
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    • 2024
  • The "Korea Institute of Geoscience and Mineral (KIGAM) Quake" is a web-based open platform developed for publicly serving seismological data from 61 stations operated by KIGAM in Korea. The service provides meta-information related to observatory sites, sensors, and recorders necessary for utilizing the seismological data, as well as mainly observed continuous and strong-motion waveforms. The data is available through both the web and International Federation of Digital Seismograph Networks (FDSN) web services (open API), a unified data-providing interface in seismology. The platform aims to strengthen its open nature by offering a signal processing function for strong ground motions that can be controlled by user requests. The processed results can be downloaded in ASCII format, designed to meet the increased demands and accessibility in the earthquake engineering field. The platform also offers earthquake research information produced by KIGAM, such as recent major earthquake source information and academic annual report of earthquakes. Additionally, a site flat file was constructed for the geotechnical characteristics of 61 KIGAM station (KGNET) sites based on direct investigations and estimations.

Probabilistic study of the influence of ground motion variables on response spectra

  • Yazdani, Azad;Takada, Tsuyoshi
    • Structural Engineering and Mechanics
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    • v.39 no.6
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    • pp.877-893
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    • 2011
  • Response spectra of earthquake ground motions are important in the earthquake-resistant design and reliability analysis of structures. The formulation of the response spectrum in the frequency domain efficiently computes and evaluates the stochastic response spectrum. The frequency information of the excitation can be described using different functional forms. The shapes of the calculated response spectra of the excitation show strong magnitude and site dependency, but weak distance dependency. In this paper, to compare the effect of the earthquake ground motion variables, the contribution of these sources of variability to the response spectrum's uncertainty is calculated by using a stochastic analysis. The analytical results show that earthquake source factors and soil condition variables are the main sources of uncertainty in the response spectra, while path variables, such as distance, anelastic attenuation and upper crust attenuation, have relatively little effect. The presented formulation of dynamic structural response in frequency domain based only on the frequency information of the excitation can provide an important basis for the structural analysis in some location that lacks strong motion records.

Characteristics of Response Spectrum using Observed Ground Motion from the Recent Earthquakes (내진설계를 위한 응답스펙트럼 연구)

  • Kim, Jun-Kyoung
    • Proceedings of the KSEEG Conference
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    • 1999.04a
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    • pp.116-119
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    • 1999
  • Amplification factor spectrum, using the observed strong ground motions database in the Korean Peninsula, has been obtained and compared with Standard Response Spectrum, which was suggested by United States Nuclear Regulatory Committee. The observed und motions from the Yongwol and the Kyoungju, and the other recent Earthquakes, respectively, which ate supposed to represent domestic seismotectonic characteristics such as seismic source, attenuation of the propagation medium, and site specific effect, are used for the analysis of amplification factor spectrum. The database are slightly different from the those of the second study. Amplification factors hue been calculated by comparing the observed peak ground motions with results from responses to the observed horizontal na vertical ground motions. The comparison have shown that the amplification factors resultant from this study exceeds these of Standard Response Spectrum, The results suggest that the characteristics of seismic strong ground motion, which are supposed to represent the domestic seismotectonic characteristics, differs from those of Standard Response Spectrum, especially at higher frequencies. The results from the 2nd study are similar to those of 1st analysis.

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Characteristics of Spectrum using Observed Ground Motions from the Yongwol and the KyoungJu Earthquakes (영월 및 경주지진 파형의 주파수 분석)

  • 김준경
    • Proceedings of the Earthquake Engineering Society of Korea Conference
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    • 1998.10a
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    • pp.407-412
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    • 1998
  • Amplification factor spectrum, using the observed strong ground motions database, has been obtained and compared with Standard Response Spectrum, which were suggested by US NRC. The observed ground motions from the Yongwol and the Kyoungju Earthquake, respectively, which are suppose to represent domestic seismotectonic characteristics such as seismic source, attenuation, and site effect, are used for the analysis of amplification factor spectrum. Amplification factors have been calculated by comparing the observed peak ground motions with results from responses to the observed horizontal and vertical ground motions. The comparison shows that the amplification factors resultant from this study exceeds those of Standard Response Spectum at relatively higher frequencies. The results suggest that the characteristics of the seismic strong ground motion, which are supposed to represent the domestic seismotectonic characteristics, differs from those of Standard Response Spectrum, especially at hither frequencies

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