• Journal of Korean Neurosurgical Society
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• v.30 no.sup2
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• pp.259-265
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• 2001

Objectives : Spontaneous intracerebral hemorrhage(S-ICH) is generally considered to be a mon-ophasic event. But some patients with ICH continued to bleed even after hospitalization. In order to evaluate the rebleeding and growth factor of hematoma in small volume S-ICH, 125 cases of S-ICH were reviewed retrospectively. Methods : We assesed age, sex, initial mental state, location of hemorrhage, systolic and diastolic blood pressure, blood pressure patterns, hematologic profile, trauma and stroke history, alcohol consumption and smoking history. Two subgroups-rebleeding groups versus no rebleeding groups-were compared, in terms of data analysis, with student T-test and chi-square test. Results : Substantial growth in the volume of S-ICH occurred in 21 cases(16.8%)-putamen(7 cases), thalamus(6 cases), subcortex(5 cases), cerebellum(2 cases), pons(1 case)-of the 125 patients. There was no significant difference in any of the parameters except initial systolic blood pressure(p=0.037) when patients with and without rebleeding were compared. Conclusion : The rebleeding and growth of the small volume S-ICH was related to the markedly elevated initial systolic blood pressure(${\geq}180mmHg$) and labile pattern of blood pressure.

• KIPS Transactions on Software and Data Engineering
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• v.2 no.3
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• pp.199-204
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• 2013

An implementation method of real-time numeral recognizer based on gesture is presented in this paper for various information devices. The proposed algorithm steadily captures the motion of a hand on 3D open space with the Kinect sensor. The captured hand motion is simplified with PCA, in order to preserve the trace consistency and to minimize the trace variations due to noises and size changes. In addition, we also propose a new HMM using both the gradient and the positional features of the simplified hand stroke. As the result, the proposed algorithm has robust characteristics to the variations of the size and speed of hand motion. The recognition rate is increased up to 30%, because of this combined model. Experimental results showed that the proposed algorithm gives a high recognition rate about 98%.

• YAKHAK HOEJI
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• v.44 no.5
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• pp.470-477
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• 2000

WooHwangChungSimWon is a traditional medicine for treatment of hypertension, arteriosclerosis, coma, and stroke in China, Korea, and Japan. In the new prescription of WooHwangChungSimWon, the civet is substituted for the musk, the major component of WooHwangChungSimwon, because of the prohibition law about the musk. We have made a comparative study of the effects on the central nervous system between the musk containing and civet containing WooHwangChungSimWon. In order to investigate the effects on the central nervous system, we have examined spontaneous motor activities, anti-convulsion activities induced by chemicals or electric shock, sleep induced by hexobarbital, and antistress effects. In the examination of anti-convulsion effects against the electric shock and injection of pentetrazol, only the civet containing WooHwangChungSimWon showed the anti-convulsion effects, i.e. the duration of convulsion by electric shock was decreased (control: 104.0 seconds, low dose of civet containing WooHwangChungSimWon: 60.7 seconds) and the duration of suppression against pentetrazol induced convulsion was increased (control: 392.3 seconds, low dose of civet containing WooHwangChungSimWon: 574.0 seconds, high dose of civet containing WooHwangChungSimWon: 561.4 seconds). In the other examinations, all kinds of WooHwangChungSimWon showed sedation, anti-convulsion activities, and induction of sleeping. These results suggest that there are no significant differences between the musk containing and civet containing WooHwangChungSimWon except the anti-convulsion effects against the convulsions induced by electric shock and pentetrazol.

• Journal of Convergence for Information Technology
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• v.9 no.10
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• pp.187-194
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• 2019

This study is a descriptive study for analyzing cigarette warning picture and message effect according to smoking status (smoking, non-smoking, ex-smoking). A total of 219 subjects participated in the study. Data collection was conducted from June 4, 2017 to June 14, 2017. The survey was conducted by using the 10 cigarette warning pictures(heart disease, stroke, lung cancer, laryngeal cancer, oral cancer) and cigarette warning messages selected by the Ministry of Health and Welfare in 2016. The results of the study showed that there was a statistically significant difference in smoking cessation intention between smoking, non-smoker and ex-smoker groups after exposure of smoking warning picture and cigarette warning message(F=36.08, p<.001). Therefore, it is suggested that the contents of cigarette warning picture and warning messages including T.V Anti-Smoking Public Service Announcement need to be replaced regularly in order to improve the smoking cessation of smokers according to National Health Promotion Act.

• Journal of Korean Medicine for Obesity Research
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• v.2 no.1
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• pp.95-104
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• 2002

Objects. There was an increase in obese population due to eating habits resulted in modernization of lifestyle and the change of the tendency to conduct the physical activity, in order words, the reduction in the range of kinetic energy. Obesity is viewed as a major risk factor for serious health problems, including heart disease, high blood pressure, stroke, diabetes, and certain forms of cancer as well as for psychological and social problems owing to our fat-phobic society. In the present study, we investigate the weight loss thanks to giving Handayulso-tang(HD) medication of Taeum-in to induced obesity rats and its effects on lipid metabolism, given that their behavior patterns are changed according to their constitution. Methods: The extracts of Handayulso-tang was orally administered to the rats of HD group 200mg/200g of rats weight every day for 6 weeks, and the control group were fed with equal amount of saline. And measured the body weight and total cholesterol, triglyceride, free fatty acid and total lipid contents in serum in obese rats. Results: 1. The body weight in HD group were decreased. 2. The contents of serum total cholesterol and triglyceride in HD group were decreased and statistically showed the significant difference compared with the control group. 3. The contents of serum free fatty acid and total lipid in HD group were decreased, but did not statistically show the significant difference compared with the control group. Conclusion: Based on the above results, we know that Handayulso-tang have effects on the decrease of the body weight and the contents of serum total cholesterol, triglyceride, free fatty acid and total lipid So it could be concluded that Handayulso-tang can help the treatment of obesity.

• Earthquakes and Structures
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• v.17 no.2
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• pp.143-162
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• 2019

Motivated by a simpler and more compact hybrid active tuned mass damper (ATMD) system with wide frequency spacing (i.e., high robustness) but not reducing the effectiveness using the least number of ATMD units, the active tuned tandem mass dampers (ATTMD) have been proposed to attenuate undesirable oscillations of structures under the ground acceleration. Likewise, it is expected that the frequency spacing of the ATTMD is comparable to that of the active multiple tuned mass dampers (AMTMD) or the multiple tuned mass dampers (MTMD). In accordance with the mode generalised system in the specific vibration mode being controlled (simply referred herein to as the structure), the closed-form expression of the dimensionless displacement variances has been derived for the structure with the attached ATTMD. The criterion for the optimum searching may then be determined as minimization of the dimensionless displacement variances. Employing the gradient-based optimization technique, the effects of varying key parameters on the performance of the ATTMD have been scrutinized in order to probe into its superiority. Meanwhile, for the purpose of a systematic comparison, the optimum results of two active tuned mass dampers (two ATMDs), two tuned mass dampers (two TMDs) without the linking damper, and the TTMD are included into consideration. Subsequent to work in the frequency domain, a real-time Simulink implementation of dynamic analysis of the structure with the ATTMD under earthquakes is carried out to verify the findings of effectiveness and stroke in the frequency domain. Results clearly show that the findings in the time domain support the ones in the frequency domain. The whole work demonstrates that ATTMD outperforms two ATMDs, two TMDs, and TTMD. Thereinto, a wide frequency spacing feature of the ATTMD is its highlight, thus deeming it a high robustness control device. Furthermore, the ATTMD system only needs the linking dashpot, thus embodying its simplicity.

• Journal of Korean Society of Rural Planning
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• v.28 no.2
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• pp.33-40
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• 2022

The purpose of this study is to review the effect of previous research data with virtual reality-based Physical Activity Therapy Programs(PATPs) in adult on the physical fitness factors. Research articles were retrieved from 2008 to 2021 with the Research Information Sharing Service(RISS) and Pubmed database. The main search terms were 'care', 'therapy', 'healing', 'exercise' or 'physical activity', and 'virtual reality'. The criteria for selecting articles of this study were the originality, duplication, Randomized controlled trial(RCT) experiment and subject. Finally, 18 papers were selected among 318 articles, which were excluded if any of the criteria was not satisfied. Most of papers(15) were conducted in the last 5 years, because of the high interest due to the development of virtual reality implementation technology and COVID-19 pandemic. The participants were mainly patients(8), and the types of diseases were stroke(2). The physical fitness factors were mostly balance ability(7), muscle strength(7), and range of motion(6). All the physical fitness factors were significantly improved after PATPs. However, 11 studies were conducted for less than 4 weeks, including 6 studies were performed a bout of acute exercise. Also, 14 studies did not clearly present the intensity of PATPs. In addition, there were 9 studies, that simply applied games without specialized programs. In conclusion, it seems that virtual reality-based PATPs have a positive effect on physical fitness factors. However, VR-based PATPs should be specialized and developed in order to verify their effectiveness for the further research.

• Journal of Pharmacopuncture
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• v.26 no.1
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• pp.60-66
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• 2023

Objectives: Discussions regarding "medical blind spots" in Korea's "aging society" are continuously rising. In addition, the demand for medical attention and care for the elderly and vulnerable populations continues to increase. Given this, the government is promoting the "home healthcare service" project. This study aims to lay the foundation for promoting this project by investigating the perception of clinical Korean Medicine (KM) doctors in the "community health care" project. Methods: With the cooperation of the Association of Korean Medicine, we sent a questionnaire to all KM doctors through e-mail. The survey included personal information, awareness, appropriate disease and intervention, proper visit location, and pros and cons. Results: A total of 602 responses were collected and analyzed. Approximately 20% of the doctors answered that they were well aware of the service, while 55% responded that they did not know about it. For a visit, a KM doctor selected the appropriate diseases in the order of stroke, dementia and Parkinson's disease, osteoarthritis, and chronic diseases. Among treatments, acupuncture, moxibustion, and herbal medicine exhibited similar results. The most common opinion was that KM doctors should schedule their visits once a week for 6-12 months, which was the most prolonged period among the given options. More than 80% (84.1%) of the doctors replied that care projects were highly essential, and about 63.8% expressed their willingness to participate in these projects. Conclusion: To provide appropriate home health care, we must raise awareness among Korean medicine doctors. In addition, the healthcare budget must be increased to provide the required support.

• Journal of Applied Biological Chemistry
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• v.66
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• pp.221-226
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• 2023

Proper activation and aggregation of platelets are necessary, but excessive or abnormal aggregation can lead to cardiovascular diseases such as stroke, thrombosis, and atherosclerosis. Therefore, identifying a substance that can regulate or inhibit platelet aggregation is important for preventing and treating these diseases. Several studies have shown that certain ginsenoside compounds in Panax ginseng can inhibit platelet aggregation. Among these compounds, Rk3 (G-Rk3) from Panax ginseng needs to be further explored in order to reveal the mechanisms of action during inhibition. G-Rk3 significantly increased amounts of cyclic adenosine monophosphate (cAMP) and led to significant phosphorylation of cAMP-dependent kinase substrates vasodilator-stimulated phosphoprotein and inositol 1,4,5-trisphosphate receptor. Furthermore, the effect of G-Rk3 extended to the inhibition of PI3K/Akt phosphorylation resulting in the reduced secretion of intracellular granules. Ultimately, G-Rk3 effectively inhibited platelet aggregation. Therefore, we suggest G-Rk3's potential as a prophylactic or therapeutic agent for cardiovascular diseases caused by faulty platelet aggregation.

• Earthquakes and Structures
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• v.27 no.1
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• pp.1-15
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• 2024

In order to enhance the seismic performance of base-isolated structures on soft foundations, the hybrid system of base-isolated system (BIS) and shape memory alloy inerter (SMAI), referred to as BIS+SMAI, is for the first time here proposed. Considering the nonlinear hysteretic relationships of both the isolation layer and SMA, and soil-structure interaction (SSI), the equivalent linearized state space equation is established of the structure-BIS+SMAI system. The displacement variance based on the H₂ norm is then formulated for the structure with BIS+SMAI. Employing the particle swarm optimization, the optimization design methodology of BIS+SMAI is presented in the frequency domain. The evolvement rules of BIS+SMAI in the effectiveness, robustness, SMA driving force, inertia force, stroke, and damping enhancement effect are revealed in the frequency domain through changing the inerter-mass ratio, structural height, aspect ratio, and relative stiffness ratio between the soil and structure. Meanwhile, the validation of BIS+SMAI is conducted using real earthquake records. Results demonstrate that BIS+SMAI can effectively reduce the isolation layer displacement. The inerter can significantly increase the hysteretic displacement of SMA and thus enhance its energy dissipation capacity, implying that BIS+SMAI has better effectiveness than BIS+SMA. Although BIS+SMAI and BIS+ tuned inerter damper (TID) have practically the same effectiveness, BIS+SMAI has the lower optimum damping, significantly smaller inertia force, and higher robustness to perturbations of the optimum parameters. Therefore, BIS+SMAI can be used as a more engineering realizable hybrid system for enhancing the performance of base-isolated structures in soft soil areas.