• 한국자동차공학회논문집
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• 제22권4호
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• pp.145-151
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• 2014

Modern vehicle has a lot of ECU(Electronic Control Unit) products to control many parts such as engine, transmission, brake, body and so on. ECU quality is one of important factors related to vehicle quality and driver's safety. Based on Bath-tub curve which presents failure rate during product lifetime, we designed and applied Accelerated Run-in Test into manufacturing line by simulating stress amount to ECU and developing the required software and efficient test equipment for mass production. This test makes ECU products stressed through electrical and thermal stresses under excessive driving condition, which induce potential initial failure of components in the ECU during production. The outcome until these days proved that Acceleration Run-in Test have reduced initial failure rates and increased quality of ECU products in the field outstandingly.

• Asian-Australasian Journal of Animal Sciences
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• 제29권5호
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• pp.731-738
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• 2016

Glucagon-like peptide-2 (GLP-2) is important for intestinal barrier function and regulation of tight junction (TJ) proteins, but the intracellular mechanisms of action remain undefined. The purpose of this research was to determine the protective effect of GLP-2 mediated TJ and transepithelial electrical resistance (TER) in lipopolysaccharide (LPS) stressed IPEC-J2 cells and to test the hypothesis that GLP-2 regulate TJ and TER through the phosphatidylinositol 3-kinase (PI3K)-protein kinase B (Akt)-mammalian target of rapamycin (mTOR) signaling pathway in IPEC-J2 cells. Wortmannin and LY294002 are specific inhibitors of PI3K. The results showed that $100{\mu}g/mL$ LPS stress decreased TER and TJ proteins occludin, claudin-1 and zonula occludens protein 1 (ZO-1) mRNA, proteins expressions (p<0.01) respectively. GLP-2 (100 nmol/L) promote TER and TJ proteins occludin, claudin-1, and zo-1 mRNA, proteins expressions in LPS stressed and normal IPEC-J2 cells (p<0.01) respectively. In normal cells, both wortmannin and LY294002, PI3K inhibitors, prevented the mRNA and protein expressions of Akt and mTOR increase induced by GLP-2 (p<0.01) following with the significant decreasing of occludin, claudin-1, ZO-1 mRNA and proteins expressions and TER (p<0.01). In conclusion, these results indicated that GLP-2 can promote TJ's expression and TER in LPS stressed and normal IPEC-J2 cells and GLP-2 could regulate TJ and TER through the PI3K/Akt/mTOR pathway.

• The Korean Journal of Physiology and Pharmacology
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• 제13권2호
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• pp.85-89
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• 2009

Puerariae flos (PF) is a traditional oriental medicinal plant and has clinically been prescribed for a long time. The purpose of the present study was to examine the effect of PF on repeated stress-induced alterations of learning and memory on a Morris water maze (MWM) test in ovariectomized (OVX) female rats. The changes in the reactivity of the cholinergic system were assessed by measuring the immunoreactive neurons of choline acetyltransferase (ChAT) in the hippocampus after behavioral testing. The female rats were randomly divided into four groups: the nonoperated and nonstressed group (normal), the sham-operated and stressed group (control), the ovariectomized and stressed group (OS), and the ovariectomized, stressed and PF treated group (OSF). Rats were exposed to immobilization stress (IMO) for 14 d (2 h/d), and PF (400 mg/kg, p.o.) was administered 30 min before IMO stress. Results showed that treatments with PF caused significant reversals of the stress-induced deficits in learning and memory on a spatial memory task, and also increased the ChA T immunoreactivities. In conclusion, administration of PF improved spatial learning and memory in OVX rats, and PF may be useful for the treatment of postmenopausal-related dementia.

• 한국방재학회 논문집
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• 제2권4호
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• pp.131-141
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• 2002

지하주차장을 PC화할 때 각각의 부재 접합상태에 따라 설계방법 및 시공방법에 많은 차이가 발생하게 된다. 특히 PC 벽체를 상호 연결하기 위한 접합부에서 수평철근을 겹침이음 방법에 의해 접합하는 경우, 수평철근의 이음길이를 충분히 확보하여야 하기 때문에 시공성이 저하되는 문제점이 있다. 따라서, PC 벽체 수평철근의 돌출길이를 최소화하기 위하여 철근 비부착 기법 및 철근 절단 기법을 적용하는 것을 본 연구의 목적으로 하고 있다. 즉, 철근 콘크리트 부재에서의 위험단면의 위치는 일반적으로 부재의 단부가 되고, 철근의 정착길이는 이 위험단면으로부터의 길이가 된다. 그런데 위험단면의 위치를 비부착 철근 공법 및 철근 절단 공법을 사용하여 부재 안쪽으로 이동함으로서, 수평철근의 정착길이를 최소화시킬 수 있다. 본 연구에서는 철근 비부착 기법 및 철근 절단 기법의 적용 가능성을 파악하기 위해 5개의 실험체를 실물크기로 제작하여 실험적 연구를 실시하고, 절단 철근 및 비부착 철근이 시험체의 거동에 미치는 영향을 비교 및 분석한 결과, 위험단면의 이동을 위하여 철근 비부착 기법 및 철근 절단 기법의 사용이 가능한 것으로 판단된다.

• Computers and Concrete
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• 제17권2호
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• pp.201-214
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• 2016

The outer tank of a liquefied natural gas (LNG) storage tank is a longitudinally and meridianally pre-stressed concrete (PSC) wall structure. Because of the current trend of constructing larger LNG storage tanks, the pre-stressing forces required to increase wall strength must be significantly increased. Because of the increase in tank sizes and pre-stressing forces, an extreme loading scenario such as a bomb blast or an airplane crash needs to be investigated. Therefore, in this study, the blast resistance performance of LNG storage tanks was analyzed by conducting a blast simulation to investigate the safety of larger LNG storage tanks. Test data validation for a blast simulation of reinforced concrete panels was performed using a specific FEM code, LS-DYNA, prior to a full-scale blast simulation of the outer tank of a 270,000-kL LNG storage tank. Another objective of this study was to evaluate the safety and serviceability of an LNG storage tank with respect to varying amounts of explosive charge. The results of this study can be used as basic data for the design and safety evaluation of PSC LNG storage tanks.

• 대한전기학회:학술대회논문집
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• 대한전기학회 1988년도 추계학술대회 논문집 학회본부
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• pp.147-150
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• 1988

Since the integration level of VLSI circuits progresses very quickly, a highly reliable thin $SiO_2$ film is required to fabricate a small-geometry MOS device. In the present study we have attempted to eliminate the failure-causing defects that develop in thin oxide films during the oxidation step by performing a long-time preoxidation and postoxidation annealing. The TDDB test and the copper decoration method were used to calculate the oxide defects density of MOS device. The dielectric reliability of high-quality thin oxides have been studied by using the time-zero-dielectric-breakdown (ramp-voltage-stressed I-V) and time-dependent-dielectric -breakdown (Constant-stressed I-V) tests. Failure times against temperature and electric field are examined and acceleration factors are abtained for each parameter. Based on the data obtained, breakdown wearout limitation for thin oxide films is estimated.

• Journal of Nutrition and Health
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• 제30권8호
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• pp.920-929
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• 1997

This study examined the effect of dietary salt levels on the incidence and cure of gastric ulcer in rats. Two sets of experiment were conducted . In the first experiment, the rats were divided into 3 groups. The 3 groups were fed 0%, 4%, and 8% NaCl diets respectively for 20days. The rats were given water -immersion restraint stress at the end of the dietary period , and sacrificed. The ulcer index by histological test was higher in rats fed the 8% NaCl diet than those in the other groups. The hexosamine and glutathione levels were significantly lower in the rats fed the 8% NaCl diet. Hematocrit and total iron binding capacity(TIBC) showed lower values caused by bleeding of gastric mucosa. The second experiment was designed to determine the effect of soldium concentration on the cure of gastric ulcer . As the gastric ulcer was recovered, ulcer length was gradually deceased in the control group but not changed in the 8% NaCl diet group. The gastric hexosamine and hepatic glutathione were increased in the control group but decreased in the 8% NaCl diet group. The hematologic indices of stressed rats showed the same tendency. As a result, dietary salt per se did not cause gastric ulcer . Once an ulcer is formed by stress or any other factor, higher levels of dietary salt may be detrimental to gastric mucosa, thereby delaying the healing of the ulcer. It is recommended that dietary salt intake be reduced in stress-prone people.

• 대한음성학회지:말소리
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• 제25_26호
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• pp.52-64
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• 1993

This paper aims to explore the rhythmic phenomena of standard Korean by an experimental phonetic method. A total of 16 informants taking part in this experiment were divided into four groups : old males(OM) and old females(OF) in their fifties and young males(YM) and young females(YF) in their twenties. The informants were asked to read speech data consisting of two rhythmic units, each of which began with a stressed syllable with a long wowel. Starting with the frame / 'ma:1 'ma:nta /, the first rhythmic unit was expanded up to five syllables in all while keeping the second rhythmic unit constant with a view to investigate the pattern of increase in the interstress time interval. The results of this study are as follows: 1. There is a considerable difference between yen and old generations with respect to the duration of interstress interval . The young generation tends to speak faster than the old generation. This observation is supported by difference in the interstress intervals as exhibited by OM(389.66), OF(473), YM(275.55), YF(285.83) in the test frame '말 많다' ['ma:1 'ma:nta]. 2. Young and old generations showed a different tendency in the increase rate of duration between mono-syllables and polysyllables. In other words, the rhythm of young generation shows the tendency of syllable-timed language whereas that of old generation clearly leans towards the stressed-timed language.

• Composites Research
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• 제16권6호
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• pp.1-9
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• 2003

본 논문에서는 웨이블 분포 함수를 이용한 확률 파손 해석을 통해 복합재 압력 용기의 섬유 강도를 예측하였다. 그리고 섬유 강도의 크기 효과를 확인하고 해석의 타당성을 입증하기 위하여 섬유 인장 시편, 한 방향 복합재 시편과 복합재 압력 용기를 이용만 강도 시험이 수행되었다. 해석적 방법으로 웨이블 최약 링크 파손 모델과 다단계 연속 파손 모델을 이용하였고, 해석 결과를 상호 비교하였다. 크기 효과에 의해, 시편의 부피가 증가함에 따라 섬유 인장 강도가 감소하는 경향을 나타내었다. 해석을 통해 예측한 한 방향 복합재 시편과 복합재 압력 용기의 후프 층 섬유 강도 분포는 시험 값과 좋은 일치를 보였다. 섬유 강도의 크기 효과는 소재와 제작 공정 변수의 함수로서, 다른 소재 및 제작 공정에 대해서는 다른 크기 효과를 보이게 된다.

• 조명전기설비학회논문지
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• 제27권3호
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• pp.79-86
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• 2013

In order to analyze the electrical performance of ZnO surge arresters stressed by the combined DC and AC voltages that are generated in DC/AC converter systems, the leakage current properties of ZnO surge arrester blocks deteriorated by impulse currents were investigated. The test specimens were deteriorated by the 8/$20{\mu}s$ impulse current of 2.5kA and the leakage currents flowing into the deteriorated zinc oxide(ZnO) arrester blocks subjected to the combined DC and power frequency AC voltages are measured. As a result, the leakage currents flowing through deteriorated ZnO surge arrester blocks were higher than those flowing through the fine ZnO surge arrester blocks and the larger the injection number of 8/$20{\mu}s$ impulse current of 2.5kA is, the greater the leakage current is. The leakage current-voltage curves(I-V curves) of the fine and deteriorated ZnO surge arrester blocks stressed by the combined DC and AC voltages show significant difference in the low conduction region. Also the cross-over phenomenon is observed at the voltage close to the knee of conduction on plots of I-V curves.