• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2021.10a
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• pp.266-267
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• 2021

Recently, the COVID-19 Pandemic is not an infectious disease-level disaster, but a complex disaster, making it difficult to respond with traditional disaster response management methods. As a result, experiencing psychological stress and trauma such as COVID-19 has emerged as a new social problem. In preemptively predicting and effectively responding to these psychological disasters and crises, the necessity and direction of non-face-to-face disaster psychological support using ICT technology in traditional services are discussed.

• 대한생식의학회:학술대회논문집
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• 2000.06a
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• pp.13-28
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• 2000

Human spermatozoa exhibit a capacity to generate ROS and initiate peroxidation of the unsaturated fatty acids in the sperm plasma membrane, which plays a key role in the etiology of male infertility. The short half-life and limited diffusion of these molecules is consistent with their physiologic role in key biological events such as acrosome reaction and hyperactivation. The intrinsic reactivity of these metabolites in peroxidative damage induced by ROS, particularly $H_2O_2$ and the superoxide anion, has been proposed as a major cause of defective sperm function in cases of male infertility. The number of antioxidants known to attack different stages of peroxidative damage is growing, and it will be of interest to compare alpha-tocopherol and ascorbic acid with these for their therapeutic potential in vitro and in vivo. Both spermatozoa and leukocytes generate ROS, although leukocytes produce much higher levels. The clinical significance of leukocyte presence in semen is controversial. Seminal plasma confers some protection against ROS damage because it contains enzymes that scavenge ROS, such as catalase and superoxide dismutase. A variety of defense mechanisms comprising a number of antioxidants can be employed to reduce or overcome oxidative stress caused by excessive ROS. Determination of male infertility etiology is important, as it will help us develop effective therapies to overcome excessive ROS generation. ROS can have both beneficial and detrimental effects on the spermatozoa and the balancing between the amounts of ROS produced and the amounts scavenged at any moment will determine whether a given sperm function will be promoted or jeopardized. Accurate assessment of ROS levels and, subsequently, OS is Vital, as this will help clinicians both elucidate the fertility status and identify the subgroups of patients that respond or do not respond to these therapeutic strategies. The overt commercial claims of antioxidant benefits and supplements for fertility purposes must be cautiously looked into, until proper multicentered clinical trials are studied. From the current data it appears that no Single adjuvant will be able to enhance the fertilizing capacity of sperm in infertile men, and a combination of the possible strategies that are not toxic at the dosage used would be a feasible approach.

• Molecules and Cells
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• v.24 no.3
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• pp.394-408
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• 2007

Several genes/QTLs governing resistance/tolerance to abiotic and biotic stresses have been reported and mapped in rice. A QTL for submergence tolerance was found to be co-located with a major QTL for broad-spectrum bacterial leaf blight (bs-blb) resistance on the long arm of chromosome 5 in indica cultivars FR13A and IET8585. Using the Nipponbare (japonica) and 93-11 (indica) genome sequences, we identified, in silico, candidate genes in the chromosomal region [Kottapalli et al. (2006)]. Transcriptional profiling of FR13A and IET8585 using a rice 22K oligo array validated the above findings. Based on in silico analysis and arraying we observed that both cultivars respond to the above stresses through a common signaling system involving protein kinases, adenosine mono phosphate kinase, leucine rich repeat, PDZ/DHR/GLGF, and response regulator receiver protein. The combined approaches suggest that transcription factor EREBP on long arm of chromosome 5 regulates both submergence tolerance and blb resistance. Pyruvate decarboxylase and alcohol dehydrogenase, co-located in the same region, are candidate downstream genes for submergence tolerance at the seedling stage, and t-snare for bs-blb resistance. We also detected up-regulation of novel defense/stress-related genes including those encoding fumaryl aceto acetate (FAA) hydrolase, scramblase, and galactose oxidase, in response to the imposed stresses.

• Journal of Oriental Neuropsychiatry
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• v.12 no.2
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• pp.193-202
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• 2001

Purpose: Hwabyung is a culture-bound syndrome in Korea, characterized by emotional stress such as anger, depression, and anxiety. The purpose of the present study was to explore the characteristics of Hwabyung patients, based on constitutional medicine, for their symptoms, duration, and coping styles. Method: Participants were 57 Hwabyung patients selected by Hwabyung criteria. They were also diagnosed for their constitution by doctors specialized in constitutional medicine. Each participant was asked to respond to a variety of items such as cause and duration of stress, symptoms of hwabyung, anger and depression, and coping styles. Eight patients were excluded from the total sample; two male patients and six patients unable to be diagnosed for any particular type of constitution. Thus, final sample was 49 female hwabyung patients, which will be reported in what follow. Result: To begin with, constitutional type revealed significant differences in such coping styles as 'perseverance,' 'positive interpretation,' 'positive comparison,' and 'emotional pacification.' More specifically, post-hoc comparison revealed that Taeeumin(person who have taeeum characteristics) was higher in 'perseverance' compared-to other two types of constitution. Taeumin also revealed higher score than Soeumin(person who have soeum characteristics) in 'positive comparison.' With respect to the marital status, the married compared to the unmarried showed higher score in 'anger-control,' and lower score in 'anger-in.' The married compared to the unmarried, regarding coping styles, also showed higher score in 'accommodation,' but lower score in 'emotional expression.' The duration of hwabyung revealed that the longer duration of hwabyung, the more frequent utilization of 'positive interpretation' and 'emotional pacification. Conclusion: The main purpose, the exploration of hwabyung based on four types of constitution, was not supported, as a whole in the present study. However, marital status and duration of hwabyung appear to influence on emotional stress (e.g., anger) as well as coping styles, suggesting that these variables should be dealt with in future studies on hwabyung.

• Journal of Microbiology and Biotechnology
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• v.20 no.4
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• pp.749-756
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• 2010

In many conditions, bacterial surface properties are changed as a result of variation in the growth medium and conditions. This study examined the influence of bile salt concentrations (0-0.1%) on colony morphotype, hydrophobicity, $H_2O_2$ concentration, S-layer protein production, and slpA gene expression in Lactobacillus acidophilus ATCC 4356. It was observed that two types of colonies (R and S) were in the control group and the stress condition. When the bile level increased in the medium, the amount of S type was more than the R type. A stepwise increment in the bile concentration resulted in a stepwise decline in the maximum growth rate. The results showed that hydrophobicity was increased in 0.01%-0.02% bile, but it was decreased in 0.1% bile. Treatment by bile (0.01%-0.1%) profoundly decreased $H_2O_2$ formation. S-Layer protein and slpA gene expression were also altered by the stress condition. S-Protein expression was increased in the stress condition. The slpA gene expression increased in 0.01%-0.05% bile and it decreased in 0.1% bile. However, we found that different bile salt concentrations influenced the morphology and some surface properties of L. acidophilus ATCC 4356. These changes were very different in the 0.1% bile. It appears that the bacteria respond abruptly to 0.1% bile.

• Korean Journal of Psychosomatic Medicine
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• v.12 no.1
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• pp.3-14
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• 2004

In this article, the effects of stress on central nerve system and heart function and the concept of heart rate variability were reviewed. HRV(Heart Rate Variability), the periodical change of the heart rate, is indicated larger in the healthier because they respond flexibly to various sorts of facts influencing on HR. HRV analysis is largely composed of the time domain analysis and the frequency analysis. In the former the flexibility of heart function is analysed, while in the latter autonomic nerve function is examined, which is the degree of sympathetic and parasympathetic nerve activity and the state of balance. Furthermore, existence or nonexistence of disease and/or level of stress can be estimated by measuring the variability and normality of heart rate, and balance of autonomic nerve system, and through HRV biofeedback the symptoms of anxiety disorder or asthma can be reduced.

• The Journal of Korean society of community based occupational therapy
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• v.3 no.2
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• pp.67-74
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• 2013

Objective : The purpose of this study is to investigate the relation between sociodemographic characteristics and attitude of job for occupational therapist. Method : Among 125 occupational therapists who voluntarily responded on structured survey final subject of study is total 123 persons except two occupational therapists who did not respond completely. Result : Attitude of Job was significantly different according to employment status and hospital types, and job stress was significantly different according to employment status and job directivity was significantly different according to hosipital types. Also, for correlation of job attitude, job satisfaction was high as higher job stability, lower job stress, and higher job directivity. Conclusion : To improve attitude of job, employment status should be regularized and the education and improvement of labor conditions are necessary to improve attitude of job and job directivity.

• Journal of Microbiology and Biotechnology
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• v.26 no.12
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• pp.2106-2115
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• 2016

To identify the global effects of (p)ppGpp in the gram-positive bacterium Deinococcus radiodurans, which exhibits remarkable resistance to radiation and other stresses, RelA/SpoT homolog (RSHs) mutants were constructed by direct deletion mutagenesis. The results showed that RelA has both synthesis and hydrolysis domains of (p)ppGpp, whereas RelQ only synthesizes (p)ppGpp in D. radiodurans. The growth assay for mutants and complementation analysis revealed that deletion of relA and relQ sensitized the cells to $H_2O_2$, heat shock, and amino acid limitation. Comparative proteomic analysis revealed that the bifunctional RelA is involved in DNA repair, molecular chaperone functions, transcription, the tricarboxylic acid cycle, and metabolism, suggesting that relA maintains the cellular (p)ppGpp levels and plays a crucial role in oxidative resistance in D. radiodurans. The D. radiodurans relA and relQ genes are responsible for (p)ppGpp synthesis/hydrolysis and (p)ppGpp hydrolysis, respectively. (p)ppGpp integrates a general stress response with a targeted re-programming of gene regulation to allow bacteria to respond appropriately towards heat shock, oxidative stress, and starvation. This is the first identification of RelA and RelQ involvement in response to oxidative, heat shock, and starvation stresses in D. radiodurans, which further elucidates the remarkable resistance of this bacterium to stresses.

• Journal of Periodontal and Implant Science
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• v.28 no.1
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• pp.103-120
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• 1998

Prokaryotic and eukaryotic cells respond to heat stress and other environmental abuses by synthesizing a small set of stress proteins and by inhibiting post-transcription synthesis of normal proteins. The purpose of the present study was to document the stress response produced by inflamed gingival tissue in vivo, and cytokine inducted human periodontal ligament cells. Human PDL cells were exposed to TNF-$\alpha$(1ng/ml), INF-$\gamma$(200 U/ml), LPS(100ug/ml), combination of cytokine, and SDS-PAGE gels running and Western blotting analysis was done. In vivo studies, the healthy gingival tissusse of a control group and inflamed gingival tissue of adult periodontitis were studied by immunohistochemistry and histology. The results were as follows 1. HSP 47 was distributed on basal layer in healthy gingiva, but stronger stained in basal, suprabasal, and spinous layer of inflamed gingiva. 2. HSP 47 was rare on endothelial cells and mononuclear cells in healthy gingiva, but stronger expressed in inflamed gingiva. 3. HSP 70 expression was rare on epihelium and inflammatory cells hi both healthy & inflamed gingiva. 4. HSP 70 was actively expressed on endothelial cells and inflammatory cells of capillary lumen in moderately & mild inflamend gingiva. 5. PDL cells showed low level of HSP 47 protein expression which was significantly induced by cytokine stimulation (LSP only and combination). 6. Maximum HSP 70 protein induction was seen with stimulation by a combination of the cytokine, Combination of TNF-$\alpha$, INF-$\gamma$, LPS have been shown to synergistically effects of HSP 70 expression. On the above findings, HSP Is influenced by cytokine and chronic inflammation in vivo, and may be involved in protection of tissue during periodontal inflammatiom.

• The Journal of the Convergence on Culture Technology
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• v.9 no.1
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• pp.407-412
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• 2023

When a traumatic subject experiences extreme stress, various psychiatric problems, including PTSD, can occur if they do not respond appropriately. In addition, non-war soldiers who experience life-threatening events while serving in the military may experience severe and chronic PTSD symptoms. However, there are still insufficient domestic studies on what traumatic events soldiers are exposed to and how much PTSD symptoms they experience. Therefore, this study provides a method that can be used as basic data for PTSD and psychological support of military service personnel by identifying trends in domestic research. Furthermore, it studies PTSD not only of soldiers but also of 'civilians' who have experienced combat, and provides symptomatic treatment and relief programs to civilians according to the difference in PTSD between general trauma and war trauma. It is expected that these studies will increase military confidence and enable the military to play a leading role in war trauma PTSD research and prevention, treatment and mitigation.