• Transactions of the Korean Society of Mechanical Engineers
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• v.13 no.5
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• pp.999-1011
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• 1989

A consideration on the trubulence models for describing the redeveloping turbulent boundary layer beyond separation-reattachment in the flow over a backward-facing step is given through experimental and numerical studies. By considering the blance among the measured values of respective terms in the transport equations for the turbulent kinetic energy and the turbulent shear stress, the recovering process of the redeveloping boundary layer from non-equilibrium to equilibrium has been investigated, which takes place slowly over a substantial distance in the downstream direction. In the numerical study, the standard K-.epsilon. model and the Reynolds stress model have been applied to two kinds of flow regions, one for the entire downstream region after the backward-facing step and another for the downstream region after reattachment. Then the results are compared to a meaningful extent, with the experimental values of the turbulent kinetic energy k, the turbulent energy production term P, the dissipation term K-.epsilon. model, a necessity for a new modelling has been brought forward, which can be also applied to the case of the nonequlibrium turbulent flow.

• Journal of Digital Convergence
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• v.17 no.3
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• pp.221-226
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• 2019

The characteristic of the beta wave among the EEG waves corresponds to the stress area of human perception. The over-bandwidth of the stress is extracted by analyzing the beta-wave correlation between the low-bandwidth and high-bandwidth. We present a KMeans clustering analysis model for unsupervised machine learning to construct an analytical model for analyzing and extracting the beta-wave correlation. The proposed model classifies the beta wave region into clusters of similar regions and identifies anomalous waveforms in the corresponding clustering category. The abnormal group of waveform clusters and the normal category leaving region are discriminated from the stress risk group. Using this model, it is possible to discriminate the degree of stress of the cognitive state through the EEG waveform, and it is possible to manage and apply the cognitive state of the individual.

• Journal of Ginseng Research
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• v.43 no.4
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• pp.499-507
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• 2019

Background: Ginsenoside Rb1 (Rb1), a dominant component from the extract of Panax ginseng root, exhibits neuroprotective functions in many neurological diseases. This study was intended to investigate whether Rb1 can attenuate cisplatin-induced memory impairments and explore the potential mechanisms. Methods: Cisplatin was injected intraperitoneally with a dose of 5 mg/kg/wk, and Rb1 was administered in drinking water at the dose of 2 mg/kg/d to rats for 5 consecutive wk. The novel objects recognition task and Morris water maze were used to detect the memory of rats. Nissl staining was used to examine the neuron numbers in the hippocampus. The activities of superoxide dismutase, glutathione peroxidase, cholineacetyltransferase, acetylcholinesterase, and the levels of malondialdehyde, reactive oxygen species, acetylcholine, tumor necrosis factor-${\alpha}$, interleukin-$1{\beta}$, and interleukin-10 were measured by ELISA to assay the oxidative stress, cholinergic function, and neuroinflammation in the hippocampus. Results: Rb1 administration effectively ameliorates the memory impairments caused by cisplatin in both novel objects recognition task and Morris water maze task. Rb1 also attenuates the neuronal loss induced by cisplatin in the different regions (CA1, CA3, and dentate gyrus) of the hippocampus. Meanwhile, Rb1 is able to rescue the cholinergic neuron function, inhibit the oxidative stress and neuroinflammation in cisplatin-induced rat brain. Conclusion: Rb1 rescues the cisplatin-induced memory impairment via restoring the neuronal loss by reducing oxidative stress and neuroinflammation and recovering the cholinergic neuron functions.

• Computers and Concrete
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• v.27 no.3
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• pp.199-210
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• 2021

The aim of this paper was to examine the continuous and discontinuous contact problems between the functionally graded (FG) layer pressed with a uniformly distributed load and homogeneous half plane using an analytical method and FEM. The FG layer is made of non-homogeneous material with an isotropic stress-strain law with exponentially varying properties. It is assumed that the contact at the FG layer-half plane interface is frictionless, and only the normal tractions can be transmitted along the contacted regions. The body force of the FG layer is considered in the study. The FG layer was positioned on the homogeneous half plane without any bonds. Thus, if the external load was smaller than a certain critical value, the contact between the FG layer and half plane would be continuous. However, when the external load exceeded the critical value, there was a separation between the FG layer and half plane on the finite region, as discontinuous contact. Therefore, there have been some steps taken in this study. Firstly, an analytical solution for continuous and discontinuous contact cases of the problem has been realized using the theory of elasticity and Fourier integral transform techniques. Then, the problem modeled and two-dimensional analysis was carried out by using ANSYS package program based on FEM. Numerical results for initial separation distance and contact stress distributions between the FG layer and homogeneous half plane for continuous contact case; the start and end points of separation and contact stress distributions between the FG layer and homogeneous half plane for discontinuous contact case were provided for various dimensionless quantities including material inhomogeneity, distributed load width, the shear module ratio and load factor for both methods. The results obtained using FEM were compared with the results found using analytical formulation. It was found that the results obtained from analytical formulation were in perfect agreement with the FEM study.

• Journal of the Korea Society of Computer and Information
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• v.29 no.4
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• pp.105-114
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• 2024

The purpose of this study was to identify factors influencing maladaptive perfectionism, self-leadership, and social support on nursing students' clinical practice stress. Participants were 150 nursing students who were enrolled at four universities in Chungcheongbukdo. Data were collected using questionnaire by from 03 to 30 November, 2022. The measurement tools consisted of the Almost Perfect Scale-Revised, Self Leadership Questionnaire-Revidsed, Scale of Social Support, and Clinical Practice Stress Scale-Revised. Results revealed that higher levels of maladaptive perfectionism were associated with increased clinical practice stress. Decreased self-leadership, satisfaction with nursing major, number of clinical practice in other regions, and social support was also associated with increased clinical practice stress. Findings indicate that specific characteristics such as maladaptive perfectionism and decrease of social support can lead to increase clinical practice stress. In this paper, we propose that active considerations for these psychological characteristics are important when reducing clinical practice stress for nursing students.

• The Korean Journal of Nuclear Medicine
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• v.27 no.2
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• pp.191-194
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• 1993

Apparent washout of T1-201 may occur between redistribution and reinjection images. To examine the frequency of it, we prospectively compared 4-hour redistribution and reinjection images in 63 consequent patients. All patients underwent pharmacological stress test using 0.56 mg/kg dipyridamole. Immediately after the 4-hour redistribution images, 1 mCi T1-201 was injected at rest, and images were reacquired 10 minutes after reinjection. The stress, redistribution, and reinjection images were then analyzed semiquantitatively (0=no uptake, 1=faint uptake, 2=mildly diminished uptake, 3=normal uptake). Of the 100 abnormal myocardial regions on the stress images, 54 showed either complete or partial reversibility on 4-hour redistribution images. After reinjection 11(21.2%) of these regions demonstrated apparent T1-201 washout due to low differential uptake of the tracer. Such lesions would appear irreversible if redistribution imaging is not performed before reinjection. Thus 4-hour redistribution imaging should be performed for assessment of myocardial ischemia and viability.

• Journal of dental hygiene science
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• v.15 no.4
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• pp.518-526
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• 2015

The purpose of this study was to relationship between self-esteem and employment, appearance. This survey was performed on 483 of university students in some regions. The research was performed using a self-reported questionnaire. Self-esteem was higher in the first, fourth grade and college of military science & police administration, college of medical science. Job-seeking stress was higher in the fourth grade and college of global business adminstration, college of medical engineering. Job preparation behavior was higher in the fourth grade and college of rehabilitation & welfare education. Interest in appearance & appearance management behavior was higher in the female, fourth grade, college of global business adminstration. Higher self-esteem group showed significant interactive effects between the job preparation behavior, appearance management behavior. Job-seeking stress has also been investigated as a much higher employment preparation behavior. In conclusion, increasing the self-esteem of education in the college will be able to raise the employment.

• Journal of Microbiology
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• v.35 no.4
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• pp.309-314
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• 1997

The manganese-containing superoxide dismutase (MnSOD) is a major component of the cellular defence mechanisms against the toxic effects of the superoxide radical. Within the framework of studies on oxidative stress=responsible enzymes in the Candida sp., the gene encoding the MnSOD was isolated and examined in this study. A specific primer was designed based on conserved regions of MnSOD sequences from other organisms, and was used to isolate the gene by PCR on reverse-transcribed Candida poly($A^{+}$) RNA. The PCR product was used to screen a Candida genomic lambda library and the nucleotide wequence of positive clone was determined. The deduced primary sequence encodes a 25kDa protein which has the conserved residues for enzyme activity and metal binding. The 28 N-terminal amino acids encoded by the Candida cDNA comprise a putatice mitochondrial transit peptide. Potential regulatory elements were identified in the 5' flanking sequences. Northern blot analysis showed that the transcription of the MnSOD gene is induced 5-to 10-fold in response to mercury, cadmium ions and hydrogen peroxide.

• Journal of Korean Academy of Nursing
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• v.36 no.6
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• pp.1042-1054
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• 2006

Purpose: Previous evaluation studies of the visiting nursing program explained an average change of the participants' health status, without considering socio-ecological characteristics and their impacts. However, these factors must affect individual health problems and lifestyles. For effective and appropriate community based programs, the Geographical Information System(GIS) can be utilized. GIS is a computer-based tool for mapping and analyzing things that happen on earth, and integrates statistical analysis with unique visualization. The purpose of this study was to evaluate visiting nursing care and to advocate the usefulness of planning and evaluating visiting nursing programs using Exploratory Spatial Data Analysis(ESDA) with GIS technology. Methods: One hundred eighty-four elderly participants with cerebrovascular risk factors who lived in 13 areas of one community received visiting nursing care. The data analyzed characteristics of pre-post change and autocorrelation by ESDA using GIS technology. Results: Visiting nursing care showed an improvement in the participants' lifestyle habits, and family management ability and stress level, while the improvements were different depending on the regions. The change of family management ability and stress level correlated with neighborhoods (Morgan's I=0.1841, 0.1675). Conclusions: Community health providers need to consider the individual participant's health status as well as socio-ecological factors. Analysis using GIS technology will contribute to the effective monitoring, evaluation and design of a visiting nursing program.

• Journal of the Korean Society for Precision Engineering
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• v.32 no.12
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• pp.1073-1080
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• 2015

A drive shaft is used to transmit torque and rotation through the connection of components of a drive train. Recently, a monobloc drive shaft without welding regions is developed to improve the safety of the drive shaft. The drive shaft bears the shear stress induced by torque. The objective of this paper is to investigate into the structural safety of a monobloc tubular drive shaft subjected to torque. Elasto-plastic finite element (FE) analysis is performed to estimate the deformation behavior of the drive shaft and stress-strain distribution in the drive shaft. Several techniques are used to create finite element (FE) model of the monobloc tubular drive shaft subjected to torque. Through the comparison of the results of FE analyses with those of experiments from the viewpoint of rotational angle, appropriate correction coefficients for different load conditions are estimated. The safety of the tubular drive shaft is examined using the results of FE analyses for different load conditions. Finally, it is noted that the designed tubular drive shaft has a sufficient structural safety.