• Health Policy and Management
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• v.30 no.2
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• pp.221-230
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• 2020

Background: The purpose of this study is to identify the factors affecting the depressive mood experience of adults in their 20s. Methods: This study is a descriptive survey that conducted a secondary analysis using data from the 2017 Community Health Survey, which is conducted annually in Korea. The study targets 21,324 adults in their 20s. Data analysis was conducted after creating a composite sample plan file that reflected layering variables, colony variables, and weights. Results: Factors affecting the depressive mood experience were suicide thought experience, subjective stress level, gender, monthly household income, smoking status, subjective health level, breakfast status, participation in social activities, and whether the Internet, games, and smartphone interfered with daily life (p<0.05). Conclusion: It is necessary to establish and realize a system that enables early detection and support of depression and suicide high-risk groups at the individual, home, community, and national levels.

• Journal of Life Science
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• v.32 no.10
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• pp.812-820
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• 2022

Depression is a psychiatric disorder characterized by depressed mood, anhedonia, fatigue, and altered cognitive function, leading to a decline in daily functioning. In addition, depression is a serious and common mental illness not only in an individual's life but also in society, so it must be actively treated. Autophagy is involved in the pathophysiological mechanism of mental illness. According to a recent study, it is known that autophagy-induced apoptosis affects neuroplasticity and causes depression and that antidepressants regulate autophagy. Autophagy is a catabolic process that degradation and removes unnecessary organelles or proteins through a lysosome. And, it is essential for maintaining cellular homeostasis. Autophagy is activated in stress conditions, and depression is a stress-related disease. Stress causes damage to cellular homeostasis. Recently, although the role of autophagy mechanisms in neurons has been investigated, the autophagy of depression has not been fully studied. This review highlights the new evidence for the involvement of autophagy in the pathophysiological mechanisms and treatment of depression. To highlight the evidence, we present results from clinical and preclinical studies showing that autophagy is associated with depression. Understanding the relevance of autophagy to depression and the limitations of research suggest that autophagy regulation may provide a new direction for antidepressant development.

• Asian-Australasian Journal of Animal Sciences
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• v.30 no.11
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• pp.1598-1604
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• 2017

Objective: The present study investigated the litter performance of multiparous sows fed 3% and 6% densified diets at farrowing to weaning during summer with mean maximum room temperature of $30.5^{\circ}C$. Methods: A total of 60 crossbred multiparous sows were allotted to one of three treatments based on body weight according to a completely randomized design. Three different nutrient levels based on NRC were applied as standard diet (ST; metabolizable energy, 3,300 kcal/kg), high nutrient level 1 (HE1; ST+3% higher energy and 16.59% protein) and high nutrient level 2 (HE2; ST+6% higher energy and 17.04% protein). Results: There was no variation in the body weight change. However, backfat thickness change tended to reduce in HE1 in comparison to ST treatment. Dietary treatments had no effects on feed intake, daily energy intake and weaning-to-estrus interval in lactating sows. Litter size, litter weight at weaning and average daily gain of piglets were significantly greater in sows in HE1 compared with ST, however, no difference was observed between HE2 and ST. Increasing the nutrient levels had no effects on the blood urea nitrogen, glucose, triglyceride, and creatinine at post-farrowing and weaning time. The concentration of follicle stimulating hormone, cortisol and insulin were not affected by dietary treatments either in post-farrowing or weaning time. The concentration of blood luteinizing hormone of sows in ST treatment was numerically less than sows in HE2 treatment at weaning. Milk and colostrum compositions such as protein, fat and lactose were not affected by the treatments. Conclusion: An energy level of 3,400 kcal/kg (14.23 MJ/kg) with 166 g/kg crude protein is suggested as the optimal level of dietary nutrients for heat stressed lactating sows with significant beneficial effects on litter size.

• Journal of Ginseng Research
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• v.47 no.2
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• pp.319-328
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• 2023

Background: Demyelination has been observed in neurological disorders, motivating researchers to search for components for enhancing remyelination. Previously we found that Rb1, a major ginsenoside in Korean Red Ginseng (KRG), enhances myelin formation. However, it has not been studied whether Rb1 or KRG function in remyelination after demyelination in vivo. Methods: Mice were fed 0.2% cuprizone-containing chow for 5 weeks and returned to normal chow with daily oral injection of vehicle, KRG, or Rb1 for 3 weeks. Brain sections were stained with luxol fast blue (LFB) staining or immunohistochemistry. Primary oligodendrocyte or astrocyte cultures were subject to normal or stress condition with KRG or Rb1 treatment to measure gene expressions of myelin, endoplasmic reticulum (ER) stress, antioxidants and leukemia inhibitory factor (LIF). Results: Compared to the vehicle, KRG or Rb1 increased myelin levels at week 6.5 but not 8, when measured by the LFB⁺ or GST-pi⁺ area within the corpus callosum. The levels of oligodendrocyte precursor cells, astrocytes, and microglia were high at week 5, and reduced afterwards but not changed by KRG or Rb1. In primary oligodendrocyte cultures, KRG or Rb1 increased expression of myelin genes, ER stress markers, and antioxidants. Interestingly, under cuprizone treatment, elevated ER stress markers were counteracted by KRG or Rb1. Under rotenone treatment, reduced myelin gene expressions were recovered by Rb1. In primary astrocyte cultures, KRG or Rb1 decreased LIF expression. Conclusion: KRG and Rb1 may improve myelin regeneration during the remyelination phase in vivo, potentially by directly promoting myelin gene expression.

• Child Health Nursing Research
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• v.28 no.2
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• pp.154-165
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• 2022

Purpose: This study aimed to analyze the concept of transfer anxiety in parents of children transferred from pediatric intensive care units to general wards. Methods: The hybrid model by Schwarz-Barcott and Kim was used to analyze the characteristics of transfer anxiety in parents of children transferred from pediatric intensive care units to general wards. Results: Transfer anxiety was defined by the following attributes: 1) stress concerning the adaptation process, 2) concern about the child's condition worsening due to the parent's caregiving, and 3) involuntary changes in daily life due to the treatment. Transfer anxiety has the following antecedents: 1) uncertainty; 2) a lack of knowledge about the illness, medical devices, and caregiving; and 3) a lack of social support. It resulted in 1) caregiver burden, 2) a decrease in the capacity for coping with caregiving, 3) delays in the child's physical and psychological recovery, and 4) decreased quality of life. Conclusion: It is necessary to develop an assessment scale that considers the attributes of transfer anxiety in parents of children transferred from pediatric intensive care units to general wards. Furthermore, an effective nursing intervention should be developed to reduce transfer anxiety.

• Journal of the Korean Society of Manufacturing Process Engineers
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• v.21 no.9
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• pp.110-116
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• 2022

As the spread of COVID-19 continues, cleanliness and quarantine are emphasized in daily life. If foreign substances enter through the shoe sole when using public facilities, cleanliness may deteriorate and various infections may occur. To prevent this, shoe sole cleaners that filter out foreign substances have been developed. In this study, a design that satisfies structural safety was presented by selecting a new material and updating the design parameter to reduce the weight of the shoe sole cleaner. To evaluate the structural safety, a finite element analysis under selected design loads was performed. Through design improvement and stress analysis, a model that was approximately 85% lighter than the existing model was developed.

• Journal of Korean Home Economics Education Association
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• v.20 no.1
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• pp.1-19
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• 2008

The purpose of this study was to find out the stress level, dietary behavior score, and relationship between stress level and dietary behavior score of middle school male students in Daejeon. Eight items of stress such as family, study, amusement, health, friend, girl friend, teacher, and daily life, and 3 items of eating behavior such as diet regularity, dietary balance and healthy diet were analyzed. The data were gathered by questionnaires from 140 students in Joong gu, Daejeon city during July 10 to 14, 2006 and 128 questionnaires(91.4%) were analyzed. The conclusion of this study were summarized as follows: 1st, the total stress level was 2.36 out of 5 full scales. The study related stress was the highest 2.93, and the stress related to girl friend was the lowest, 1.96, though there were no significant differences among the 8 kinds of stress items. 2nd, the total score of dietary behavior was 3.02 out of 5 full scales. 3rd, when the students were divided into 3 groups(low, meddle, and high group) according to the stress level, the middle group showed the highest score of dietary behavior, while the high group showed the lowest score, but non-significant. 4th, according to the relationships between stress levels and dietary behavior scores, significant relationships were found between the total stress score and dietary balance. And diet regularity score were influenced by stress items such as family related, study related, and health related.

• Research in Community and Public Health Nursing
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• v.15 no.2
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• pp.218-227
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• 2004

Purpose: The purpose of this study was to determine the effects of 5 weeks self-help management program developed by Kim et al. (2000-b) and reinforced with music therapy for post stroke patients. Method: This was pre-experimental study and the subjects were 14 post stroke hemiplegic patients at home who were registered at the Gunsan Health Center. The program was applied for five weeks and two hours for each session composed of the preparation step, the main step and the finishing step. The contents of the program were ROM exercise, daily activity training, risk factors and aftereffects, nutrition management and stress management. To collect data, all subjects were questioned before and after the application of the program. Collected data were analyzed through frequencies, percentages, Wilcoxen signed rank test and Cronbach's alpha using SPSS-WIN program. Result: After the application of the self-help management program, a statistically significant increase was observed in the subjects' ability to perform activities of daily living (p=.039), ability to perform instrumental activities of daily living (p=.005), self-efficacy (p=.001), self-care behavior (p=.001) and quality of life (p=.001), and a statistically significant decrease was observed in depression (p=.012). Conclusion: The present self-help management program was found to be helpful in improving the subjects' physical and psychological functions after they were attacked by stroke, so to be an effective nursing intervention strategy for post stoke patients. Future researches need to reinforce and materialize music therapy and to develop and apply a self-help management program that includes not only post stroke patients but also their families. In addition, it is necessary to expand the scope of subjects and apply follow-up management in order to continue self-help meetings.

• Journal of the Korean Dietetic Association
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• v.23 no.3
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• pp.316-327
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• 2017

This study was conducted to compare the nutrient intake, physical characteristics, and health status according to daily fruits and vegetables intake of adolescents using the Korean national health and nutrition examination survey for the sixth period (2013~2015). Subjects were 1,096 adolescents aged 13~18 years. The average daily intake of fruits and vegetables was $518.49{\pm}4.94g$. The two groups (insufficient, sufficient) were divided by fruits and vegetables intake (<500 g/day, ${\geq}500g/day$) and the ratio of the insufficient group was 75.9% while that of the adequate group was 24.1%. The mean of intake of energy, calcium, phosphorus, sodium, potassium, iron, thiamin, niacin, vitamin C and dietary fiber differed significantly between the insufficient and sufficient groups (P<0.01, P<0.001). However, there was no significant difference in physical characteristics between groups. The self-perceived health status was better in the sufficient group (P<0.05), while the insufficient group was aware of more stress in their daily life (P<0.05). The serum triglyceride was significantly higher in the sufficient group (P<0.05), while the total cholesterol was lower (P<0.05). As the characteristics of fruits and vegetables are different, it will be necessary to determine standards for consumption of each type. It is also necessary to consider whether a fruits and vegetables intake of 500 g would be a reasonable standard for adolescents. Nevertheless, the results of this study indicate efforts to increase fruits and vegetables intake by young people are necessary.

• Journal of Korean Physical Therapy Science
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• v.9 no.2
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• pp.49-66
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• 2002

This study was designed to evaluate the effect of pelvic floor muscle strengthening exercise treatment program for the older women with stress incontinence. The researcher developed 8 weeks training program which was implemented at a social welfare center in Seoul. The exercise method followed the Kegel criteria. Verbal instructions were given to the subjects. Subjects were confirmed of the exercises and evaluated by description of the exercise method. Fourteen elderly women(mean age 75.7) with stress incontinence participated and completed this program. The training sessions were held twice a week and each session took 45 minutes ; 15 minutes for pelvic floor muscle strengthening program and 30 minutes for other physical therapy. Pelvic floor muscle strengthening exercise program was applied using verbal instruction and practice at social welfare center, twice a week and daily home exercise program were given to each individual. The results were as follows ; 1. There was significant decrease of lower urinary symptoms in the subjects (p = 0.00) 2 But there was no significant change in the sexual matters (p = 0.44) and the life style (p = 0.41) In conclusion, further study with larger sample group is suggested in order to confirm the study result. Because of limited sample size, the study results were not conclusive. But the pelvic floor muscle strengthening exercise treatment program could be a safe and effective program and is suggestive for the community residing older women with stress incontinence as a geriatric physical therapy intervention.