• Journal of Animal Science and Technology
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• 제58권4호
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• pp.17.1-17.7
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• 2016

Background: The Sapsaree (Canis familiaris) is a Korean native dog that is very friendly, protective, and loyal to its owner, and is registered as a natural monument in Korea (number: 368). To investigate large-scale gene expression profiles and identify the genes related to exercise-induced stress in the Sapsaree, we performed whole-transcriptome RNA sequencing and analyzed gene expression patterns before and after exercise performance. Results: We identified 525 differentially expressed genes in ten dogs before and after exercise. Gene Ontology classification and KEGG pathway analysis revealed that the genes were mainly involved in metabolic processes, such as programmed cell death, protein metabolic process, phosphatidylinositol signaling system, and cation binding in cytoplasm. The ten Sapsarees could be divided into two groups based on the gene expression patterns before and after exercise. The two groups were significantly different in terms of their basic body type ($p{\leq}0.05$). Seven representative genes with significantly different expression patterns before and after exercise between the two groups were chosen and characterized. Conclusions: Body type had a significant effect on the patterns of differential gene expression induced by exercise. Whole-transcriptome sequencing is a useful method for investigating the biological characteristics of the Sapsaree and the large-scale genomic differences of canines in general.

• 동의신경정신과학회지
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• 제22권3호
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• pp.23-42
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• 2011

Objectives : The purpose of this study was to investigate the difference of somatization psychological mechanism among Sasang constitution. Methods : Subjects were seventy four students of Won-Kwang university responded the questionnaire. We evaulated the subjects using Minnesota Questionnaire for the Sasang Constitution Classification II(QSCC II), Multiphasic Personality Inventory-2(MMPI-2), 20-item Toronto Alexithymia Scale (TAS-20), Somato-Sensory Amplification Scale(SSAS), Symptom Interpretation Questionnaire(SIQ) and The Ways of Stress Coping Questionnaire(SCQ). Results : From the results of Clinical scale of MMPI-2, the scores of 2nd, 9th, 10th scales was significantly difference. In Lesser Yin group 10th score was the significantly highest of the others, 1st, 3rd, 6th, 7th, 8th score were the highest but not significant. and From the results of PSY-5 scale(The Personality Psychopathology Five scale) of MMPI-2, In Lesser Yin goup, INTR(Introversion/Low Positive Emotion) score was significantly highest, PSYC(psychoticism), NEGE (Negative Emotionality/Neuroticism) was higher than the others. In TAS-20K, SSAS, SIQ and SCQ Lesser Yin group was not significantly difference. but Lesser Yin group had the tendency of difficulty describing feelings and externally oriented thinking and higher score in physical and psychological interpretation. We observed generally lower levels of stress coping strategy scores than the others. Conclusions : These results showed that Lesser Yin group tend to somatization compared other constitution.

• Plant Breeding and Biotechnology
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• 제5권2호
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• pp.123-133
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• 2017

AP2/EREBP gene family consists of transcription factor genes with a conserved AP2 DNA-binding domain and is involved in various biological processes. AP2/EREBP gene families were identified through genome-wide searches in five Cucurbitaceae species including cucumber, wild cucumber, melon, watermelon, and bitter gourd, which consisted of more than 100 genes in each of the five species. The gene families were further divided into five groups including four subfamilies (ERF, DREB, AP2 and RAV) and a soloist group. Among the subfamilies, DREB subfamily which is known to be related to abiotic stress response was more analyzed and a total of 25 genes were identified as Cucurbitaceae homologues of Arabidopsis CBF/DREB1 genes which are important for abiotic stress-response and tolerance. In silico expression profiling using RNA-Seq data revealed diverse expression patterns of cucumber AP2/EREBP genes. AP2/EREBP gene families identified in this study will be valuable for understanding the stress response mechanism as well as facilitating molecular breeding in Cucurbitaceae crops.

• 벤처창업연구
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• 제15권4호
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• pp.277-301
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• 2020

본 연구는 최근 세계보건기구(WHO)가 공식 질병으로 인정한 게임이용장애 분류기준이 국내에 도입되었을 때 어떠한 효과가 나타날 것인지 알아보기 위해 일반 성인 503명을 대상으로 설문조사를 시행하였다. 응답자의 사전지식 수준차를 고려하여 절반의 응답자를 게임이용장애 분류에 관한 정보성 기사를 제공하는 집단에 무선할당하였다. 또 국내 게임중독 선행연구를 종합적으로 검토하여 연구목적에 맞게 응답자를 정상이용집단과 잠재적 문제이용집단으로 분류하여 분석을 시행하였다. 그 결과, 게임이용장애 분류코드 등록은 정상집단과 잠재적 문제집단 모두에서 게임시간 24%, 게임비 28%, 이용 게임수 22%가 감소하는 등 전반적인 게임 수요를 감소시키는 영향을 갖는 것으로 나타났다. 잠재적 문제이용집단의 경우 게임이용장애 공식화 후 게임비용이 증가하더라도 게임비를 기꺼이 더 지불하겠다는 의향이 정상집단에 비해 높은 것으로 나타났고, 스트레스 수준이 높은 집단도 추가 비용 지불 의향이 높았는데, 이는 게임중독 문제 해결을 위한 정책의 효과가 미쳐야 하는 대상 집단에 오히려 경제적 비용 증가가 발생하는 역설적 영향이 발생할 수 있음을 시사한다. 따라서 게임장애 관련 정책을 수립할 때 이러한 문제집단, 특히 '스트레스 수준이 높은 집단', '자기통제력이 부족한 집단' 즉 중독성향이 높은 집단을 선별하여 정책의 타겟 집단으로 해야 질병코드 등록 정책효과가 나타날 수 있을 것으로 보인다. 또 게임장애에 관한 정보성 기사의 긍정적 효과는 이미 자기통제력 수준이 높은 게임이용자들에게만 집중적으로 나타나 정작 향후 정책의 영향을 받게 될 대상(잠재적 문제집단 중 중독성향이 강한 집단)의 태도와 행동 의도에는 별다른 영향력이 없는 것으로 확인되었다. 다시 한번 정책의 대상을 세분화하여 문제집단의 특성별로 정책을 정교화하는 핀셋 정책의 필요성을 확인하였다. 국내 여건에 관한 고려 없이 게임이용장애 분류를 도입할 경우 국내 게임이용자, 게임산업 및 유관 기업들에 부정적 영향과 손실을 끼칠 수 있으므로 산.관.학 협력을 통해 선제적 대응책을 마련해야 할것이라 판단된다.

• 한국기계가공학회지
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• 제19권6호
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• pp.55-60
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• 2020

The injection molding technique is a processing method widely used for the production of plastic parts. In this study, the gate position, gate size, packing time, and melt temperature were optimized to minimize both the stress and deformation that occur during the injection molding process of medical suction device components. We used a central composite design and Latin hypercube sampling to acquire the data and adopted the response surface method as an approximation method. The efficiency of the optimization of the injection molding problem was determined by comparing the results of a genetic algorithm, sequential quadratic programming, and a non-dominant classification genetic algorithm.

• 대한기계학회:학술대회논문집
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• 대한기계학회 2001년도 춘계학술대회논문집E
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• pp.702-707
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• 2001

The characteristics of flow in dividing regions are precise, therefore their classification is very important not only in industry but also in hydrodynamics. By now, many studies of flow in dividing regions have been performed, but flow characteristics that use visualization in dividing regions have not been studied. The present study of the PIV and the CFD exhibit average velocity distributions, kinetic energy distributions and total pressure distributions etc of the total flow field due to the development of the accurate visualization optical laser and of optical equipment. Also, PIV is accurate with the flows characteristics of the dividing region as continuous analysis is done using input equipment. The study analyzes average velocity vector field, average kinetic energy, x-axis stress distributions, average and total pressure distributions of dividing regions with flow for visualization of the PIV and the CFD measurement in a dividing rectangular duct.

• Journal of Advanced Marine Engineering and Technology
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• 제21권5호
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• pp.542-548
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• 1997

In this study an evaluation method of fatigue strength of membrane type LNG tank is presented with FEM analysis and experimental approach of seam and raised edge welds. The study contains the following : l)FEM analysis of test specimens 2)Fatigue tests of seam and raised edge welds 3)Estimation of cumulative damage factor of the welds on the basis of safe life design concept complying with the rules of classification society 4)Review of the effect of mean stress on the fatigue strength 5)Modelling of fatigue life of the welds which is changeable by weld heights With the results obtained in this study, a model ${\Delta}{\delta}/h^2=0.13553\;{N_{f}}^{-0.3151}$ for seam and raised edge welds having a given weld height is proposed to be useful for designers and inspectors.

• 한국해양공학회지
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• 제15권4호
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• pp.60-65
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• 2001

Thermal spray coating is formed by a process in which melted particles flying with high speed towards substrate, then crash and spread on the substrate surface cooled and solidified in a very short time, Stacking of the particles makes coating. In this study, the exfoliation of $Al_2$O$_3$ and Ni-4.5wt.%Al thermally sprayed coating which were deposited by an atmospheric plasma spray apparatus are investigated using an AE method. A tensile test is conducted on notch specimens in a stress range below the elastic limit of substrate. The wave forms of AE generated from the three coating specimens can be classified by FFT analysis into two types which low frequency(type I waveform is considered to corresponds exfoliation of coating layers and type II waveform corresponds the plastic deformation of notch tip or the resultant fracture of coating. The fracture of the coating layers can estimate by AE event and amplitude, because AE features increase when the deformation generates.

• 한국항해항만학회:학술대회논문집
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• 한국항해항만학회 2015년도 춘계학술대회
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• pp.338-339
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• 2015

VTS 의사결정지원시스템은 관제사들이 선박을 관제함에 있어서, 의사결정을 지원하기 위하여 선박 간 거리 등의 정보를 제공하는 시스템을 의미한다. 본 논문에서는 현재 제정되고 있는 IALA 표준을 중심으로 VTS 의사결정지원 시스템의 구분, 제공하는 경고 정보의 세분화된 정의, 제공되어야 할 경고 기능 등을 분석한다.

• 대한물리치료과학회지
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• 제8권1호
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• pp.727-734
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• 2001

Contracture is defined as the lack of full passive range of motion resulting from pint, muscle or soft tissue limitationprolonged Pint immobilization will result in stress and stretch deprivation and gradual development of contracture. the tissue changes caused by immobilization may be categorized as cellular modeling, ground substance and collagen response, and tissue response. contracture can be divided into three categories according to the anatomical location of pathological changes :arthrogenic, myogenic, soft tissue contractures Therapeutic approach of contracture is thermal or cold agents application, stretch or restoration of length, traction, manipulation, mobilization positioning and restoration of function. The purpose of this article is to review current concepts of mechanical properties and synthesis of collagen tissue and the underlying pathomechanics as it relates to evaluation and treatment of contracture.