• Food Science and Biotechnology
• /
• v.16 no.6
• /
• pp.967-974
• /
• 2007

The present work is aimed to evaluate the protective effect of glutathione-enriched Saccharomyces cerevisiae FF-8 strain on carbon tetrachloride ($CCl_4$)-induced hepatotoxicity and oxidative stress in rats. The activities of liver markers (alanine aminotransferase, aspartate aminotransferase, alkaline phosphatase, lactate dehydrogenase), lipid peroxidative index (thiobarbituric acid-reactive substances), and the antioxidant status (reduced glutathione) were used to monitor those protective roles of FF-8 strain. The liver marker enzymes in plasma and the lipid peroxidation in the liver were increased when $CCl_4$ was treated but these were significantly decreased by FF-8 strain treatment. The hepatic concentration of glutathione in the current glutathione-enriched FF-8 strain fed animal was approximately twice as high as the normal, but this was slightly increased in response to $CCl_4$ plus glutathione-enriched FF-8 strain. The increased liver triglyceride concentration due to the $CCl_4$ treatment was significantly decreased by FF-8 strain and the reduced level reached to that of normal group. Administration of FF-8 strain in normal rat did not show any signs of harmful effects. Therefore, the current findings suggest that FF-8 strain could be an effective antioxidant with no or negligible side-effects and it might be useful for the purpose of protection treatment of hepatotoxicity and oxidative stress in $CCl_4$-treatment in rat.

• Journal of the Korean Society of Hazard Mitigation
• /
• v.8 no.2
• /
• pp.39-43
• /
• 2008

Determination of strain associated with shear modulus and damping ratio during torsional test is complicated. This is due to nonuniform stress-strain variation occurring linearly with radius in a soil specimen in torsion. A conventional equivalent radius approach proposed by Chen and Stokoe appears to be adequate for evaluating strain associated with shear modulus at low to intermediate strain levels. This approach is less accurate for damping measurement, particularly at high strain. Modified equivalent radius approach was used to account for the nonuniform stress-strain effect more precisely. The modified equivalent radius approach was applied for hyperbolic, modified hyperbolic, and Ramberg-Osgood models. The results illustrate the usefulness of the modified equivalent radius approach and suggest that using a single value of equivalent radius ratio to calculate strains is not appropriate.

• Transactions of the Korean Society of Mechanical Engineers A
• /
• v.40 no.2
• /
• pp.167-173
• /
• 2016

This paper proposes ductile failure simulation under high strain rate conditions using finite element (FE) analyses. In order to simulate a cracked component under a high strain rate condition, this paper applies the stress-modified fracture strain model combined with the Johnson/Cook model. The stress-modified fracture strain model determines the incremental damage in terms of stress triaxiality (${\sigma}_m/{\sigma}_e$) and fracture strain (${\varepsilon}_f$) for a dimple fracture using the tensile test results. To validate the stress-modified fracture strain model under dynamic loading conditions, the parameters are calibrated using the tensile test results under various strain rates and the fracture toughness test results under quasi-static conditions. The calibrated damage model predicts the CT test results under a high strain rate. The simulated results were then compared with the experimental data.

• Steel and Composite Structures
• /
• v.44 no.4
• /
• pp.587-602
• /
• 2022

In this study, the classical J₂ flow theory is explicitly proved to be inappropriate to describe the plastic behaviour of structural steels under different stress states according to the reported test results. A numerical framework of the characterization of the strain hardening and ductile fracture initiation involving the effect of stress states, i.e., stress triaxiality and Lode angle parameter, is proposed based on the mechanical response of structural steels under monotonic loading. Both effects on strain hardening are determined by correction functions, which are implemented as different modules in the numerical framework. Thus, other users can easily modify them according to their test results. Besides, the ductile fracture initiation is determined by a fracture locus in the space of stress triaxiality, Lode angle parameter, and fracture strain. The numerical implementation of the proposed model and the corresponding code are provided in this paper, which are also available on GitHub. The validity of the numerical procedure is examined through single element tests and the accuracy of the proposed model is verified by existing test results.

• Smart Structures and Systems
• /
• v.20 no.1
• /
• pp.11-22
• /
• 2017

The long-term effect of ambient temperature on bridge strain is an important and challenging problem. To investigate this issue, one year data of strain and ambient temperature of a long-span cable-stayed bridge is studied in this paper. The measured strain-time history is decomposed into two parts to obtain the strains due to vehicle load and temperature alone. A linear regression model between the temperature and the strain due to temperature is established. It is shown that for every $1^{\circ}C$ increase in temperature, the stress is increased by 0.148 MPa. Furthmore, the extreme value distributions of the strains due to vehicle load, temperature and the combination effect of them during the remaining service period are estimated by the average conditional exceedance rate approach. This approach avoids the problem of declustering of data to ensure independence. The estimated results demonstrate that the 95% quantile of the extreme strain distribution due to temperature is up to $1.488{\times}10^{-4}$ which is 2.38 times larger than that due to vehicle load. The study also indicates that the estimated extreme strain can reflect the long-term effect of temperature on bridge strain state, which has reference significance for the reliability estimation and safety assessment.

• Transactions of Materials Processing
• /
• v.26 no.5
• /
• pp.314-322
• /
• 2017

In the high-speed forming analysis, dynamic material properties considering a high strain rate are required. The split Hopkinson pressure bar (SHPB) experiment was performed for measuring dynamic material properties under high strain rate. The pulse shaping method was used to improve the accuracy of the SHPB experiment. A pulse shaper attached to the front of the incident bar was used for specimen dynamic stress equilibrium through stress wave control. Numerical analysis and SHPB test were performed to verify whether the pulse shaper affects the dynamic stress equilibrium in copper and Al6061 specimens. The results of SHPB test and numerical analysis show that the pulse shaper contributes to the dynamic stress equilibrium. Based on the improved stress equilibrium using a pulse shaper, the flow stress curves for copper and Al6061 materials were obtained at strain rates of 1344.4/sec and 1291.6/sec, respectively.

• Proceedings of the Korean Geotechical Society Conference
• /
• 2005.03a
• /
• pp.916-923
• /
• 2005

In this study, to observe aging effect of undrained shear behavior for Nak-Dong River sand, undrained static and cyclic triaxial tests were performed with changing relative density ($D_r$), consolidation stress ratio($K_c$) and consolidation time. As a result of the test, the modulus of elasticity to all samples estimated within elastic zone by the micro strain of about 0.05% in case of static shear behavior increased with the lapse of consolidation time significantly, so aging effect was shown largely. Also strength of phase transformation point(S_{PT}$) and strength of critical stress ratio point($S_{CSR}$) increased with the lapse of consolidation time. Undrained cyclic shear strength($R_f$) obtained from the failure strain 5% increased in proportion to relative density($D_r$) and initial static shear stress($q_{st}$), $R_f$ of consolidated sample for 1,000 minutes increased about 10.6% compared to that for 10 minutes at the loose sand, and $R_f$ increased about 7.0% at the medium sand. In situ application range of $R_f$ to the magnitude of earthquake for Nak-Dong River sand was proposed by using a increasing rate of $R_f$ as being aging effect shown from this test result.

• Steel and Composite Structures
• /
• v.28 no.1
• /
• pp.13-24
• /
• 2018

A size-dependent novel hyperbolic shear deformation theory of simply supported functionally graded beams is presented in the frame work of the non-local strain gradient theory, in which the stress accounts for only the nonlocal strain gradients stress field. The thickness stretching effect (${\varepsilon}_z{\neq}0$) is also considered here. Elastic coefficients and length scale parameter are assumed to vary in the thickness direction of functionally graded beams according to power-law form. The governing equations are derived using the Hamilton principle. The closed-form solutions for exact critical buckling loads of nonlocal strain gradient functionally graded beams are obtained using Navier's method. The derived results are compared with those of strain gradient theory.

• Transactions of Materials Processing
• /
• v.17 no.6
• /
• pp.420-428
• /
• 2008

The effect of loading path changes on the strain and mechanical properties of a commercial pure aluminum was studied using flat rolling and groove rolling. Material during flat rolling undergoes a continuous monotonic compressive loading, while one during groove rolling experiences a series of cross compressive loading. Four-pass flat rolling and groove rolling experiment are designed such that the aluminum undergoes the same amount of the strain at each pass. The rolling experiment was performed at room temperatures. Specimens for tensile test are fabricated from the plate and bar rolled. In addition, the strain distribution for the plate and bar cold rolled specimens is also calculated by finite element method. The results reveal that differences of loading path attributed by monotonic loading(flat rolling) and cross loading(groove rolling) significantly influence the mechanical properties such as yield stress, ultimate tensile stress, strain hardening and elongation. It is clear that the different loading path can give raise to change the deformation history, although it is deformed with same amount of strain for same material.

• Proceedings of the Korean Geotechical Society Conference
• /
• 2009.03a
• /
• pp.331-340
• /
• 2009

This study evaluates the relationship between cone tip resistance ($q_c$) and small-strain shear modulus ($G_{max}$) of cemented sand. For this purpose, a series of miniature cone penetration and bender element tests are performed in calibration chamber specimens with various gypsum contents. Experimental results show that both $q_c$ and $G_{max}$ of sand increase with increasing cementation level as well as relative density and vertical confining stress. However, the relative density and vertical confining stress has more significant influence on $G_{max}$ and $q_c$ of uncemented sand than those of cemented sand. It is observed that the $G_{max}/q_c$ ratio of cemented sand decreases with increasing relative density. This result means that state variables have more affect on $q_c$ than $G_{max}$ of cemented sand. Test results also show that the effect of vertical stress on $G_{max}-q_c$ relation is reduced by cementation effect.