• 동의생리병리학회지
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• 제26권4호
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• pp.497-505
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• 2012

To determine the effects of Banggihwanggi-tang(BGHGT) on obesity, the obesity-related factors[gastrin, calcitonin gene related peptide(CGRP), serotonin, ghrelin, obestatin, glucagon-like peptide-1(GLP-1), insulin, orexin, leptin] were investigated in the stomach, pancreas, brain of mice by immunohistochemical(IHC) methods for 4 weeks. The change of body weight was more reduced in BGHGT administered group than that of control group. The IHC density of the gastrin and CGRP positive cells on pylorus was higher in BGHGT administered group than that of control group. The number of ghrelin immunoreactive cells on stomach was lower in BGHGT administered group than that of control group. The IHC of GLP-1 positive cells did not observe in the stomach of BGHGT administered groups. The IHC density of GLP-1 in the pancreas was lower in BGHGT administered group than that of control group. The IHC density of insulin positive cells in the pancreas was lower in BGHGT administered group than that of control group. The IHC density of orexin positive neurons in the diencephalon was slightly higher in BGHGT administered group than that of control group. The IHC density of NPY and leptin positive neurons was slightly higher in BGHGT administered group than that of control group. The IHC density of serotonin positive neurons was higher in BGHGT administered group than that of control group. Therefore, we conclude that BGHGT activates appetite inhibitor through appetite related enteroendocrine cells and neuropeptides in stomach, pancreas and brain, and this activation may also be responsible for the inhibition of feeding behavior.

• 한방안이비인후피부과학회지
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• 제20권2호통권33호
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• pp.171-178
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• 2007

Objective : The aim of this study was to evaluate Yangdorak and D.I.T.I. for analysis of Symptom-complexes. Method : This study was selected 26 acne patients in Dongshin University Oriental Medical Hospital. We used Yangdorak (SME5800N, Sord Medicom Co., Korea) and D.I.T.I. (Digital Infrared Thermal Imaging 256, Dorex Inc, Orange CA, USA) and investigated the results of Yangdorak and D.I.T.I.. We made a comparison according to Deficiency or Excess(虛實) of acne patients. Result : In comparing Yangdorak results according to Deficiency or Excess(虛實) of acne patients, Triple-energizer(三焦), Intestine(大腸), Liver(肝), Stomach(胃) meridian in Excess group are higher than Deficiency group, and Kidney(腎) meridian in Deficiency group are lower than Excess group. D.I.T.I. reveald hyperthemia of face and chest on acne patients. The temperature of face and chest on Excess group is higher than Deficiency group. There is no statistically significant value compared with data of other group.

• 제3의학
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• 제1권1호
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• pp.115-122
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• 1996

A clinical observation was done on 98 cases performed neurometer diagnosis before Guibitang administration first, and rechecked neurometer diagnosis after Guibitang administration for 10 days. Electric current post administration was compared with ant administration. The following result were obtained. 1. A peak incidence was observed in 30-39 age group. 37 cases(37.8%) were in 30-39 age group. The ratio of male to female was 1:31.7. 2. Chief complaints were fatigue, menoxenia, indigestion, anorexia, constipation, headache, palpitation, insomnia etc. 3. The common result of neurometer point checking was that patients who had the pecularity of low electric current were much than patients who had the pecularity of high electric current. 4. By neurometer diagnosis a peak incidence was observed in gallbladder. Increment was also highest in gallbladder. Gallbladder has a function of psychomotility in oriental physiology. ?5. After Guibitang administration the increment of neurometer electric current was comparatively high in kidney, stomach, small intestine meridian. According to the above menthioned results I consider that Guibitang has the curative effects along the meridian selectively. and increases in function or preserves health within physycal limit.

• 동의생리병리학회지
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• 제24권6호
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• pp.1053-1058
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• 2010

Glycyrrhizae radix (GR) is an herbal medicine commonly used in East Asia for treating a variety of diseases, including stomach disorders. In this study, the antidepressant-like activity of GR was investigated using the forced swimming test (FST) in rats. After the FST, the expression of c-Fos and corticotrophin releasing factor (CRF) was assessed by immunochemistry of brain samples from the paraventricular nucleus of the hypothalamus (PVN). The results of the FST showed that a high dose (400 mg/kg) of extract was very effective in reducing immobility(P<0.01), and increased climbing. In addition, treatment with GR (400 mg/kg) significantly decreased the expression of c-Fos and CRF in the PVN, compared to controls. In conclusion, the findings of this study demonstrated that GR effectively reduced behavioral and physiological depression responses in an animal model of depression, suggesting that GR might be useful in the treatment of clinical depression.

• Korean Journal of Acupuncture
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• 제23권2호
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• pp.29-38
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• 2006

Objectives & Methods: This study was aimed to investigate denomination and distribution of fifteen main collaterals through oriental medicine literature. Results & Conclusions: 1. Kyung-maek-pyoun(經脈篇) of Yeong-chu (靈樞; divine pivot) says that fifteen main collaterals (十五絡脈) consist of main collaterals of the twelve regular meridians (十二經脈), Conception Channel (任孤), Governor channel (督脈) and great collateral of the spleen(脾之大絡). While chapter 26 of Nan-gyung(難經; Classic of difficulty) says that Yin-heel & Yang-heel channels are included instead of Conception channel(任脈) and Governor Channel (督脈). what is explained in Yeong-chu (靈樞; divine pivot) is considered more proper. 2. Great collateral of the stomach (胃之大絡 ) has been considered as one of the main collaterals, resulting in an opinion of sixteen main collaterals. We speculate that this is a wrong interpretation of Pyoung-in-gi-sang-lon(平人氣象論 ) of So-mun(素問). 3. Gumi (CV1) is more resonable than Hoeeum(CV14) for the Connecting point of Conception Channel(任脈) 4. Kyung-maek-pyoun (經脈篇) of Yeong-chu (靈樞; divine pivot) did not mention that the collateral of Hand Jueyin (手厥陰絡版) was running to Hand Shaoyang(手少陽經脈), which is considered to be omitted by mistake. 5. Fifteen main collaterals are mostly distributed on the legs and arms, while some are distributed in the internal organs, chest, abdomen, as well as head and five sensory organs.

• 대한한의학원전학회지
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• 제21권4호
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• pp.225-232
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• 2008

The purpose of this study is to introduce the music therapy as one of the 17 kinds of oriental medicine music therapy and investigate the record in the literature. The spleen is an organ that has the function of digestion, absorption, and supply of nutrition. Damp, anxiety, and improper diet can cause deficiency syndrome of the spleen. The symptoms of deficiency of the spleen are poor appetite, abdominal distension, borborygmus, water-grain dysentery, dyspepsia, and lack of strength in limbs. CV12, CV6, S36, B20, B21, and Sp4 are can be used as acupuncture points that are a great help to the patients who suffer from deficiency of the spleen. This study describes the theory of invigorating the spleen music therapy that has a good possibility as a new method of oriental medical treatment and present the acupuncture points that can be used with invigorating the spleen music therapy. The tone of the spleen is Gung(宮) and the sound of the spleen is related to a song. The music therapy of invigorating the spleen includes beating Earth-Gi(地氣) rhythm with Cheonnyeonmanse, stimulating Spleen Meridian and Stomach Meridian with Gayaguem sanjo jungjungmori, and acupuncture with "Le Cygne" of Camille Saint-Saens.

• Korean Journal of Acupuncture
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• 제22권4호
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• pp.149-159
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• 2005

Object : The purpose of this study is to arrange the literature about a acupuncture therapy on the gatroduodenal ulcer. Methods : We arrange twenty five kinds of literature about a acupuncture therapy on gastric pain coming within the category of the gatroduodenal ulcer. Results : The cause of gastric pain is disunion of liver and spleen caused by overeating, uncontrolled emotion. The gastric pain is accompanied by lack of appetite, nausea & vomiting, belching, constipation, abdominal discomfort and so on. Therapy methods of the gastric pain are tonifying the spleen, eliminating pathological coldness and alleviation of pain, draining the liver and replenish Ki. Acupuncture point at S36, P6, CV12, B20, B21, B18, B17 used frequently for the acupuncture therapy in the order of frequency of use. Conclusions : Meridians of Conception Vessel, Stomach, Spleen, Bladder and Liver used frequently for the acupuncture therapy. The meridian used for treatment of the gastroduodenal ulcer is related to it passing by a painful place in the body.

• 한방안이비인후피부과학회지
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• 제11권1호
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• pp.82-98
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• 1998

In the literatual studies on the causes and treatments of the melasma, the results were as follows. 1. Melasma is the blackish patch on the face, is belong to the cartegory of the 'Myunjin(面塵)', 'Myunganzung(면간증)', 'Jakban(雀斑)' etc. in Oriental medicine 2. Melasma is deeply associated with Yangming channel in Meridian, with the spleen, stomach, heart and kidney in Viscera. 3. The pathogenic factors of Melasma is divided five parts. One is insufficient of Yangming's energy in Neijing(內經). Two is incoordination between vital energy and blood caused by wind-evil and phlegm-retention syndrome. Three is anxiety impairing the spleen. Four is kidney-asthenia and fire-hyperactivity. Five is heat-evil. 4. In the treatments of Melasma, Sthenia-syndrome was used cooling blood and activating blood circulation, or dispelling wind-evil and promoting meridian, or expelling fire-evil and removing toxic material etc. Asthenia-syndrome was used invigorating the liver and kidney, or nourishing yin and keeping fire downwards etc. 5. Melasma is concerned with sun-light, is mostly seen in female. 6. In the prescription of Melasma, it was used Jujesamultang(酒製四物湯加減), Okyong -san(玉容散), Chunghwasungitang(沖和順氣湯), Okyongseosisan(玉容西施散), Yukmiji-hwanghwan(六味地黃丸) etc.

• Korean Journal of Acupuncture
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• 제21권3호
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• pp.21-38
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• 2004

Objectives : Moxibustion has been become very useful tool to prevent and treat various diseases with acupuncture in oriental medicine. Expecially, moxibustion combining the heat stimulation and chemical stimulation of Artemisiae Argyi has a non-invasive characteristics comparing to the other therapeutic tools. However, because the moxibustion makes the patient's skin be burn by the combustible feature of moxibustion, most of people have been scared of being scald. Methods : In this study, we have developed new non-combustible moxibustion tools in collaboration with company (Hana Medical, co. and ICURE, co.) and tested the efficacy through effects of moxibustion of Cheon-chu $(ST_{25})$ on the abdominal thermography of health subject. The non-combustible moxibustion has main characteristics of controlled heating to inhibit being scald and heat stimulation lasting over 1 hrs. Also, to induce the chemical stimulation, the bottom contacting with skin was coated by the extract of artemisiae argyi. The volunteers who participating in this study had taken rest for 20 - 30 mins in room temperature $(23-25^{\circ}C)$ before the examination and informed them what to prohibit smoking, drinking and administration of drug for the previous day The thermography of abdomen including a below part of the chest was taken using Infra-Red Imaging System (IR 2000, MEDI-CORE Co., Korea) by time interval of 15 minutes. Results : The results showed that moxibustion of Cheon-chu $(ST_{25})$ had more potencies of changes on all the ROIs of abdominal thermography than those of control group. Also, it was observed that the quantities of thermal changes following moxibustion of Cheon-chu $(ST_{25})$ been increased significantly comparing that of control group at all the ROIs (region of interest). Observed the thermography classified by ROI, however, moxibustion of Cheon-chu $(ST_{25})$ could modulate ipsilateral specific areas concerning to the abdominal pathway of Stomach Meridian. Conclusion : These results suggest that new non-combustible moxibusion has some similarity as like as the conventional moxibustion and moxibustion of Cheon-chu $(ST_{25})$ may modulate thermal changes of abdominal areas.

• 대한한방내과학회지
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• 제31권4호
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• pp.837-845
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• 2010

It has been shown that bilateral decrease of point H4,5,6 in Ryodoraku test is related with gastric dysmotility. This suggested that the system of Kyung-Rak related with anatomical gastric disease may not be the Stomach Meridian, in the view that the system of Kyung-Rak is similar to that of Ryodoraku, and which was not consistent with classical contents of Kyung-Rak principle. Therefore, this paper was done to investigate whether bilateral decrease of point H4,5,6 is a general sign of common gastric disease in Ryodoraku test and to study its relation between Kyung-Rak principle and autonomic nervous system as a mediator explaining Ryodoraku response. As shown in the results of this study, different electrical response of Ryodoraku between patients with dyspepsia of gastric dysmotility and gastric ulcer revealed discrepancy of location indicating anatomical stomach between Kyung-Rak principle and Ryodoraku and instability of explanation of autonomic nerve theory to Ryodoraku. Thus, it presented the possibility that artificial application of Kyung-Rak principle against Ryodoraku may destroy its originality in the clinical field. To correctly use Ryodoraku in the diagnosis or evaluation of disease, Ryodoraku test should be used according to Nakatani's suggestion and clinical indication of which is limited to the diseases complicated with dysfunction of the autonomic nervous system.