• 한국컴퓨터산업학회논문지
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• 제5권2호
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• pp.217-226
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• 2004

본 논문에서는 초음파 모터 구동형 역감 장치의 말단에 전기 자극 촉각 장치를 부착함으로써 역감과 촉감을 동시에 제시할 수 있는 단일 PC 기반의 역감-촉감 제시 시스템을 제안한다 인간이 가상 현실 공간에서 가상 물체와 접촉했을 때 동시에 역감과 촉감 정보를 제시받으면 역감 또는 촉감의 한가지 감각만을 제시받은 것 보다 더 큰 몰입감을 느끼게 된다. 또한 다양한 가상 물체를 복잡한 알고리즘 없이 쉽게 표현 또는 인식할 수 있다. 예를 들자면, 사용자가 역감장치를 사용하면 딱딱한 가상 벽과 탄성이 높은 고무공에 대한 차이점을 확실하게 구별할 수는 있으나, 송곳과 같은 날카로운 가상 물체의 경우에는 단지 딱딱함만을 제시하여 가상 벽과의 구별하기가 매우 어렵다 만약 전기 자극형 촉감장치(The Electric Stimulus Tactile Apparatus System : TESTAS)를 함께 사용한다면 딱딱함과 동시에 송곳에 찔렸을 때의 촉감을 함께 제시할 수 있어 가상 벽과의 차이점을 확실하게 구별할 수 있다.

• The Journal of Korean Physical Therapy
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• 제21권1호
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• pp.81-87
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• 2009

Purpose: Human brain was lateralized to dominant or non-dominant hemisphere, and could be reorganized by the processing of the motor learning. We reported four cases which showed the changes of the cortical activation patterns resulting from two weeks of training with the serial reaction time task. Methods: Four right-handed healthy subjects were recruited, who was equally divided to two training conditions (right hand training or left hand training). They were assigned to train the serial reaction time task for two weeks, which should press the corresponding four colored buttons as fast as accurately as possible when visual stimulus was presented. Before and after two weeks of training, reaction time and function magnetic resonance image (fMRI) was acquired during the performance of the same serial reaction time task as the training. Results: The reaction time was significantly decreased in all of subjects after training. Our fMRI result showed that widespread bilateral activation at the pre scanning was shifted toward the focused activation on the contralateral hemisphere with progressive motor learning. However, the bilateral activation was still remained during the performance of the non-dominant hand. Conclusion: These findings showed that the repetitive practice of the serial reaction time task led to increase the movement speed and accuracy, as described by motor learning. Such motor learning induced to change the cortical activation pattern. And, the changed pattern of the cortical activation resulting from motor learning was different each other in accordance with the hand dominance.

• 동국한의학연구소논문집
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• 제3권
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• pp.207-222
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• 1994

In order to find out the effect of Anti-Histamine of the Sungmagalkuntang and Sungmagalkuntang-plus-samultang I've investigated the effect of the time to death, the peripheral vascular Pemeability, the amount of secretion of Gastric Juice, the total Acidity of Gastric Juice, the contraction of Intestine Tube by Histamine and the effect of the Skin-Reaction by the decrease of DNCB. These results are following ; 1. The effect of Mice's time to death by Histamine was that the injection group of sungmagalkungtang and the injection group of sungmagalkungtang-plus-samultang both have had the effect of the extention of the time to death, which indicated a statistical significance in comparison with comparative group. 2. The effect of the increased vascular permeability by Histamine was that the injection group of sungmagalkuntang and the injection group of sungmagalkuntang-plus-samultang both have had the effect of the restraint of the increased vascular permeability, which indicated a statistical significance in comparison with comparative group. 3. The effect of the the amount of the secretion of Gastric Juice by Histamine stimulus was that the injection group of sungmagalkuntang-plus-samultang only has had the effect of restraint of the increased of the secretion of Gastric Juice, which indicated a statistical significance in comparison with comparative group. 4. The effect of the change of total Acidity of Gastric Juice by Histamine's stimulus was that the injection group of sungmagalkuntang-plus-samultang only has had the effect of the restraint of the increase of total Acidity of Gastric Juice, which indicated a statistical significance in comparison with comparative group. 5. The effect of the contraction of Intestine Tube by Histamine was that sungmagalkuntang and sungmagalkuntang-plus-samultang both have had the effect of the contraction and the restraint. According to the increase of the density, the effect of the restraint was more clear. But the difference of the effects between two substances had little. 6. The effect of the reaction of skin by the decrease of DNCB was that the injection group of sungmagalkuntang and the injection group of sungmagalkuntang-plus-samultang have had the decreased effect of the Skin-Reaction in comparison with comparative group. sungmagalkuntang-plus-samultang aws more effective. In these results shown above, both sungmagalkuntang and sungmagalkuntang-plus-samultang was shown as more effective one.

• 한국전문물리치료학회지
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• 제12권3호
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• pp.67-73
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• 2005

Prospective memory (PM) is related to remember to carry out a previously intented behaviour. The purpose of this study was to develop a paradigm for measuring PM function to diagnosis in mild cognitive impairment 1 or brain injury in patients 2. among brain injured patients Thirty-eight normal healthy subjects participated in current study. The paradigm was composed of four conditions: a baseline and three intention conditions (expectation, execution 1 and 2). In the expectation condition, subjects were asked to make a new response to intented stimuli during ongoing task, but the intented stimuli never occurred. In the execution 1 (one type of expected stimulus) and 2 (two types of expected stimuli), the intended stimuli did occur in 20% of trials. The reaction time and error rate were calculated in each condition. Repeated measures using ANOVA of subject's mean reaction times (RTs) and mean error rates (ERs) showed main effects of conditions during ongoing task. The comparison of PM tasks in executive condition 1 and 2 also showed significance in RTs and ERs. This paradigm reflects sufficiently the performance of prospective memory function during ongoing task in normal individuals. Thus, we suggest that the paradigm will be helpful to study neural network of PM function using brain imaging techniques and diagnosis of PM dysfunction.

• Molecular & Cellular Toxicology
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• 제2권4호
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• pp.251-256
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• 2006

The exploration of genes which expressions are changed by exposure to ecotoxicants or pollutants can provide the important information about the reaction mechanisms in the body as well as adaptation to exterior stimulus or environmental changes. Also they can be developed as biomarkers for the detection of environmental pollution. Differential display polymerase chain reaction (DD-PCR) technique has been usefully used to hunt the clones which expressions are up-regulated or down-regulated by exterior changes and this study aimed to search for those clones in diesel oil-exposed rockfish (Sebastes schlegeli) using DD-PCR. The RNA isolated from liver of 20 ppb diesel oil-exposed rockfish was used for screening of the differentially displayed genes and total 44 differentially expressed genes (DEG) are detected then their nucleotide sequences were analyzed. The present data provided the general information about the effect of diesel oil contamination on marine organism and further more the primary step in development of new biomarkers for marine environmental pollution or ecotoxicological stresses.

• 한국정보통신학회:학술대회논문집
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• 한국정보통신학회 2012년도 춘계학술대회
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• pp.198-201
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• 2012

연구는 근육의 기능을 조절하는 신경말단에 전기적인 자극을 가하여 신경의 반응 정도를 측정하는 플랫폼 구현에 관란 연구로써, 전기 자극에 대한 신경반응이 가해지는 전류량, 가해진느 전류지속시간, 전극위치에 따른 반응을 측정하였다. 신경자극의 전극 위치는 표면 말단에 운동신경이면 어느 신경이든지 가능하고, 신경자극 양식에는 단순연축자극(Single Twitch Stimulation), 사연속자극(Train-of-four, TOF), 두 집단 발사자극(Double Burst Stimulation, DBS)이 있다. 임베디드 시스템기반으로 가기위한 저전력 MCU를 선정하고, 기본적인 신경자극반응 측정 센서의 민감도를 알아보기 위해 센서 인터페이스를 구성하여 반응정도를 측정해야 한다. 그리고 측정된 Data의 정확도를 높이기 위해 고성능의 AD Convertor 선정하여 플랫폼을 구현하였다. 또한 본 논문의 플랫폼은 의료기기용으로 개발되었기 때문에 시스템 이용자의 안전을 고려하여 전원회로 구성 시 전원 Isolation를 고려하여 설계하였다.

• 한국정보통신학회:학술대회논문집
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• 한국해양정보통신학회 2011년도 추계학술대회
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• pp.331-334
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• 2011

본 연구는 근육의 기능을 조절하는 신경말단에 전기적인 자극을 가하여 신경의 반응 정도를 측정하는 플랫폼 구현에 관란 연구로써, 전기 자극에 대한 신경반응이 가해지는 전류량, 가해진느 전류지속시간, 전극위치에 따른 반응을 측정하였다. 신경자극의 전극 위치는 표면 말단에 운동신경이면 어느 신경이든지 가능하고, 신경자극 양식에는 단순연축자극, 사연속자극, 두 집단 발사자극이 있다. 임베디드 시스템기반으로 가기위한 저전력 MCU를 선정하고, 기본적인 신경자극반응 측정 센서의 민감도를 알아보기 위해 센서 인터페이스를 구성하여 반응정도를 측정해야 한다. 그리고 측정된 Data의 정확도를 높이기 위해 고성능의 AD Convertor 선정하여 플랫폼을 구현하였다. 또한 본 논문의 플랫폼은 의료기기용으로 개발되었기 때문에 시스템 이용자의 안전을 고려하여 전원회로 구성 시 전원 Isolation를 고려하여 설계하였다.

• 한국음향학회:학술대회논문집
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• 한국음향학회 1998년도 학술발표대회 논문집 제17권 1호
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• pp.291-296
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• 1998

In the experiment carried out on 20 college students, recorded were frontal, temporal and occipital EEG, skin conductance response, skin conductance level, heart rate and respiration rate during listening to two music fragments with different affective valences and white noise administered immediately after negative visual stimulation. Analysis of physiological patterns observed during the experiment suggests that affective auditory stimulation with music is able to selectively modulate autonomic and cortical activity evoked by preceding aversive visual stimulation and to restore initial baseline levels. On other hand, physiological responses to white noise, which does not possess emotion-eliciting capabilities, evokes response typical for orienting reaction after the onset of a stimulus and is rapidly followed by habituation. Observed responses to white noise were similar to those specific to attention only and had no evidence for any emotion-related processes. Interpretation of the obtained data is considered in terms of the role of emotional and orienting significance of stimuli, dependence of effects on the background physiological activation level and time courses of attention and emotion processes. Physiological parameters are summarized with regard to their potential utility in differentiation of psychological processes induced by auditory stimuli.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제13권3호
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• pp.332-337
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• 1991

Kimura's disease is a chronic inflammatory condition producing subcutaneous tumor-like nodules mainly head and neck regions. Elevated serum Ig E levels and peripheral blood eosinophilia are common. Kimura's disease represents and aberrant immune reaction to an as yet unknown stimulus. This case presented is 27 year old female whose chief complaint were painful swelling on Rt cheek and temporal area and diagnosed as Kimura's disease. We preformed surgical excision of the mass on Rt. cheek and temporal area and reconstructed with temporal flap and about 100 cc of free fat graft on the defect of Rt. cheek.

• 한국통신학회논문지
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• 제21권4호
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• pp.1038-1047
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• 1996

The effect of electromagnetic wave on the biobody is to make a possibility not increasing temperature but also inducing physiological and psychological damage which is head or backbone. Generally a vital function of hean can be estimated by the measureing of Electro Encephalogram(EEG), and achieved a response of a find stimulus which can not be defected a subjective sympton and out of reaction. In this paper, the head can be modeled according to its medium and dervated the equation of SAR distritution, and the head of rabbit is approximately modeled three layers practically and the result of each SAR distribution is illustrated. Measured EEG from the nervous system of rabbit on a plane wave irradiated an be used quantitative analysis for the electrophysiogical effect of the biobody.