• 한국지하수토양환경학회지:지하수토양환경
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• 제18권3호
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• pp.11-22
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• 2013

SEAWAT, a linked modeling program of Visual MODFLOW was used to analyze the change in groundwater levels and salinity related groundwater dam construction in Cheongsan island, Wando-Gun, Jeollanam-Do. The steady-state model results show the groundwater flow and salinity distribution of the studied area. The groundwater flows from north-west and south-east highlands into the river, located in the middle part of the basin, and is eventually discharged to the ocean. Part of the sea water infiltrates into the river; and through the estuary's alluvium aquifer, the sea water intrusion takes place spreading to about 830 m from the ocean. The transient model results show that after the groundwater dam construction, groundwater levels will rise to a maximum of 2.0 m upstream, and the groundwater storage will increase 21,000 after 10 years. Meanwhile 31% of the total area affected by sea water intrusion will decrease. To conclude, the groundwater dam is a very useful method for a secure water resource in preparation for drought and water shortages in the island regions.

• 한국경영과학회지
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• 제31권3호
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• pp.63-79
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• 2006

In this study we consider a CONWIP system in which the processing times at each station follow a Coxian distribution and the demands for the finished products arrive according to a compound Poisson process. The demands that are not satisfied immediately are either backordered or lost according to the number of demands that exist at their arrival Instants. For this system we develop an approximation method to calculate performance measures such as steady state probabilities of the number of parts at each station, proportion of lost demands and the mean number of backordered demands. For the analysis of the proposed CONWIP system, we model the CONWIP system as a closed queueing network with a synchronization station and analyze the closed queueing network using a product-form approximation method. A recursive technique is used to solve the subnetwork in the application of the product-form approximation method. To test the accuracy of the approximation method, the results obtained from the approximation method are compared with those obtained by simulation. Comparisons with simulation show that the approximation method provides fairly good results.

• 동력기계공학회지
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• 제21권6호
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• pp.5-12
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• 2017

The steady-state, incompressible and three-dimensional numerical analysis was carried out to investigate the internal flow fields characteristics according to wind tunnel contraction type. The turbulence model used in this study is a realizable $k-{\varepsilon}$ modified from the standard $k-{\varepsilon}$ model. As a results, the distribution of the axial mean velocity components along the central axis of the flow model is very similar to the ASME and BE types, and the cubic and cosine types. When the flow passes through the interior space of the analytical models, the flow resistance at the inlet of the plenum chamber is the largest at BS type contraction, but the smallest at cubic type contraction. The boundary layer thickness is the smallest in the cosine type contraction as the axial distance increases. The maximum turbulent kinetic energy in the test section is the smallest in the order of the contraction of cubic type and cosine type. Comprehensively, cubic type contraction is the best choice for wind tunnel performance, and cosine type contraction can be the next best solution.

• 조명전기설비학회논문지
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• 제26권12호
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• pp.1-8
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• 2012

The performance and lighting characteristics of the LED depend on cooling condition because the power LED generates lots of heat. In this paper, the effect of the generated heat from power LED module on lighting characteristics and performance is measured and evaluated. For experiments, the transient temperature of a power LED module with cooling condition is measured. In addition, the temperature and lighting characteristics of the LED module are measured during the steady state. As a result, the cooling condition is less effective on the lighting characteristics of the LED module at rated current but the cooling condition extremely affects those of the LED module over the rated current. Because high temperature of the power LED module causes the low phosphor conversion, luminance efficiency becomes low and color temperature becomes high. When power LED module are driven over the rated condition, higher temperature is directly related to lighting characteristics and performance of the LED module rather than higher current.

• 한국산업정보학회논문지
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• 제23권1호
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• pp.53-63
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• 2018

본 논문에서는 D-정책을 갖는 이산시간 BMAP/G/1 대기행렬시스템의 대기시간을 분석한다. 고객(또는 패킷)들은 마코비안 도착과정을 따라 집단으로 시스템에 도착하며, 유휴한 서버는 시스템에 도착한 고객집단의 서비스시간의 총합이 이미 정해놓은 임계값 D를 초과하면 시스템에 더 이상 서비스할 고객이 없을 때까지 서비스를 제공한다. 시스템의 안정상태 대기시간 분포를 변환 형태로 구하고 성능척도로서 평균값을 유도하였다. 시뮬레이션을 통하여 이론값들의 타당성을 검증하고 간단한 수치예제를 보였다.

• 한국터널지하공간학회 논문집
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• 제6권1호
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• pp.41-50
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• 2004

본 논문에서는 기존댐 인접지에 터널구조물을 건설하기 위한 발파시, 폭괴하중으로 인한 지반진통이 댐 제체와 간극수암에 마치는 영향을 고찰하였다. 댐의 안정성 검토는 발파시 발생하는 코어부의 최대입자속도 (Peak Particle Velocity)를 계산하여 수행하였다. 간극수와 지반진동간의 상호 연계해석을 위하여 댐 제체에 대한 정상상태 흐름해석을 수행하여 간극수압 분포를 파악하고, 유발된 과잉간극수암 및 유효응력분포로 발파하중이 인접지반에 미치는 영향을 분석하였다. 또한 발파와 같은 급속하중 재하 후 과잉간극수압의 증가 및 소산현상 해석을 위하여 Finn & Byrne Model을 적용하여 하중재하 전후의 유효응력 변화양상을 검토하였다.

• International Journal of Aeronautical and Space Sciences
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• 제18권1호
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• pp.70-81
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• 2017

Various components of an engine nozzle are modeled as flexible multi-body components that are operated under high temperature and pressure. In this paper, in order to predict complex behavior of an engine nozzle, thermo-fluid-flexible multi-body dynamics coupled analysis framework was developed. Temperature and pressure on the nozzle wall were obtained by the steady-state flow analysis for a two-dimensional nozzle. The pressure and temperature-dependent material properties were delivered to the flexible multi-body dynamics analysis. Then the deflection and strain distribution for a nozzle configuration was obtained. Heat conduction and thermal analyses were done using MSC.NASTRAN. The present framework was validated for a simple nozzle configuration by using a one-way coupled analysis. A two-way coupled analysis was also performed for the simple nozzle with an arbitrary joint clearance, and an asymmetric flow was observed. Finally, the total strain result for a realistic nozzle configuration was obtained using the one-way and two-way coupled analyses.

• Journal of Pharmaceutical Investigation
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• 제35권5호
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• pp.349-353
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• 2005

This study reports the pharmacokinetics of a novel histone deacetylase inhibitor, SD-0542, in rats after i..v. and oral administration. SD-0542 was injected intravenously at doses of 10, 20, and 40 mg/kg. The terminal elimination half-life $(t_{1/2})$, systemic clearance (Cl), and steady-state volume of distribution $(V_{ss})$ remained unaltered as a function of dose, with their values ranging from 2.0-2.5 hr, 157.2-214.1 ml/min/kg, and 11.1-17.5 L/kg, respectively, whereas, the initial serum concentration $(C_0)$ and AUC increased linearly as the dose was increased. Renal excretion of SD-0542 was minimal. Oral pharmacokinetic studies were conducted in rats at a dose of 20 mg/kg. The $T_{max}$, Cl/F, $V_{z}/F$, and $t_{1/2}$ were 2.0 hr, 92864 ml/min/kg, 16331 L/kg, and 2.0 hr, respectively. Taken together, SD-0542 showed linear pharmacokinetics over the i.v. bolus dose range studied. SD-0542 was poorly absorbed, with the absolute oral bioavailability of 0.9%.

• 한국경영과학회지
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• 제32권1호
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• pp.93-104
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• 2007

We consider a supply chain where products are shipped to warehouse from manufacturing system to customers. Products are supplied from either in-house regular manufacturing or the secondary source such as subcontractor. The inventory in warehouse is controlled by base-stock policy, that is, whenever a demand arrives from customer, an order is released to the manufacturing system. Unsatisfied demand is backlogged. The manufacturing system is modeled as M/M/s+1/c queueing system, and the orders exceeding the given limit care blocked and lost. The steady state distribution of the outstanding orders and the throughput of the manufacturing system are functions of the level of engagement In the secondary source. There is a profit obtained from throughput and cost not only due to the engagement of the secondary source in the manufacturing system but also inventory positions. We want to maximize the total production profit minus the total cost of the production system by simultaneously determining the optimal level of engagement of the secondary source and the optimal base-stock level of the inventory. We develop two algorithms : one without guarantee of the optimal solution but with the small number of computations, the other optimal but with more computations.

• 약학회지
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• 제46권1호
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• pp.30-38
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• 2002

The elderly patients are the most frequent users of digoxin because of increased prevalence of the two primary indications for digoxin therapy, fibrillation (AE) and congestive heart failure (CHF). This study performed to observe a variation in digoxin pharamcokinetic parameters in advancing age and changing kidney function and to compare the measured clearance with the calculated clearance. The 123 drug monitoring records of inpatients who had achieved steady state concentration of digoxin at a tertiary hospital from April 1999 to October 2001 were reviewed. In advancing age, measured digoxin clearance, volume of distribution and creatinine clearance were reduced. Compared with the calculated digoxin clearance, the measured digoxin clearance was more reduced in patients without CHF Especially, in elderly patients without CHF the measured digoxin clearance was lower than the calculated digoxin clearance. In contrast to nonCHF patients the measured value was greater than the calculated value in all CHF patients. Findings from this study indicate that the calculated digoxin clearance in elderly patients without CHF substantially overestimated the true clearance. Thus, it appears that the use of calculated digoxin clearance to estimate serum digoxin concentration may result in underestimation of the true serum concentration in a number of elderly patients without CHF.