• Coupled systems mechanics
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• 제11권2호
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• pp.151-166
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• 2022

Peltier cells have low efficiency, but they are becoming attractive alternatives for affordable and environmentally clean cooling. In this line, the current article develops closed-form and semianalytical solutions to improve the temperature distribution of Bi₂Te₃ thermoelements. From the distribution, the main objective of the current work-the optimal electric intensity to maximize cooling-is inferred. The general one-dimensional differential coupled equation is integrated for linear and quadratic geometry of thermoelements, under temperature constant properties. For a general shape, a piece-wise solution based on heat flux continuity among virtual layers gives accurate analytical solutions. For variable properties, another piece-wise solution is developed but solved iteratively. Taking advantage of the formulae, the optimal intensity is directly derived with a minimal computational cost; its value will be of utility for more advanced designs. Finally, a parametric study including straight, two linear, barrel, hourglass and vase geometries is presented, drawing conclusions on how the shape of the thermoelement affects the coupled phenomena. A specially developed coupled and non-linear finite element research code is run taking into account all the materials of the cell and using symmetries and repetitions. These accurate results are used to validate the analytical ones.

• 한국기계가공학회지
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• 제21권1호
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• pp.28-33
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• 2022

The heating roller of an actual pulse output device (POD) production facility is composed of a steel roller and a rubber roller. The time to reach a specific temperature and the temperature distribution on the roller surface were analyzed and compared according to the change in the number of cartridge heaters inside the heating roller. In this analysis, a steady-state thermal analysis of a steel roller was performed for the cases of a 5-cartridge heater and 9-cartridge heater. Finite element analysis was applied with reference to the surface temperature data of the heating roller during operation and the calorific value of the cartridge heater. Using the 9-cartridge heater, faster target temperature achievement and more uniform temperature distribution were confirmed than for the 5-cartridge heater.

• 농촌계획
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• 제17권1호
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• pp.13-27
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• 2011

This study analyzed the budget investment plans for the unit-project items(UPI) of 176 project districts for the rural village comprehensive development projects (RVCDP). This study classified the master plan reports of 176 project districts into 88 unit project items in aspect of project management, in order to analyze characteristics of distribution of budget in each project item. Most of all unit project items have similar types of uniform distribution with plus skewness in frequency pattern analysis except the total budget of the project district. This study analyzed the characteristics of budget distribution per province, year, and geographical types of region. Furthermore this paper also analyzed ratio of budget in unit project items to find out distribution pattern of each budget between project items over time. The hierarchical system for UPI of RVCDP consisted of three steps, which are 4 items of the first step on Strength of Rural-urban Exchange & Regional Capability (RURC), Green-income Infrastructure & Facility (GIF), Culture- health-welfare Facility, and Eco-environment & Landscape facility (ELF), 13 items for the second one, and 52 items for the third project items. From the results of the budget investment analysis for 5 years from 2004 to 2008, the budget investment ratios of RURC and ELF have steady state for every year, while GIF in decreasing and ELF in increasing over time. The ratios of UPI on infrastructure were decreased, whereas those on culture, health, and welfare were increased. Portion of tow project items among 52 items, which are community centers for village residents and rural experimental study facility, has 30% of total budget investment. Futhermore, the budget ratios of seven project items showed 50% of total budget. Average value of project budgets for five years was optimized as a type of exponential function in the case of decent array for ranking order.

• 전기학회논문지
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• 제61권11호
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• pp.1758-1764
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• 2012

A large number of wire rope has been used in various inderstiries as Cranes and Elevators from expanding the scale of the industrial market. But now, the management of wire rope is used as manually operated by rope replacement from over time or after the accident.It is caused to major accidents as well as economic losses and personal injury. Therefore its time to need periodic fault diagnosis of wire rope or supply of real-time monitoring system. Currently, there are several methods has been reported for fault diagnosis method of the wire rope, to find out the feature point from extracting method is becoming more common compared to time wave and model-based system. This method has implemented a deterministic modeling like the observer and neural network through considering the state of the system as a deterministic signal. However, the out-put of real system has probability characteristics, and if it is used as a current method on this system, the performance will be decreased at the real time. And if the random noise is occurred from unstable measure/experiment environment in wire rope system, diagnostic criterion becomes unclear and accuracy of diagnosis becomes blurred. Thus, more sophisticated techniques are required rather than deterministic fault diagnosis algorithm. In this paper, we developed the fault diagnosis of the wire rope using probability density estimation techniques algorithm. At first, The steady-state wire rope fault signal detection is defined as the probability model through probability distribution estimate. Wire rope defects signal is detected by a hall sensor in real-time, it is estimated by proposed probability estimation algorithm. we judge whether wire rope has defection or not using the error value from comparing two probability distribution.

• 대한환경공학회지
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• 제22권5호
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• pp.939-947
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• 2000

연속 회분식 반응기를 이용하여 생물학적 인 제거에 관한 미생물 분포 연구를 수행하였다. 탄소원으로 초산을 넣은 합성 폐수를 사용하였고 미생물 체류 시간과 수리학적 체류 시간은 각각 10일과 16시간으로 유지하였다. 인 방출과 흡수가 운전 시간이 경과됨에 따라 점점 빠르게 일어났으며 약 200일 경과 후 안정적인 인 제거가 유지되었다. 안정적인 생물학적 인 제거가 유지될 때의 미생물 분포를 조사하기 위하여 17개의 ribosomal RNA (rRNA) signature probe를 합성하여 슬러지로부터 분리한 전체 rRNA에 대하여 slot hybridization을 실시하였다. 분리한 전체 RNA에는 proteobacteria의 베타군 (beta subclass)에 속하는 rRNA가 가장 많이 함유되어 있음을 확인하였고 CTE probe와 관계된 rRNA가 다음으로 많이 분포하였다. 전통적으로 생물학적 인 제거를 담당하는 미생물로 여겨져 왔던 Acinetobacter, Aeromonas, Pseudomonas의 rRNA는 10% 미만으로 존재하고 있음이 확인되었다. 이러한 결과로부터 Rhodocyclus 그룹같은 proteobacteria의 베타군과 CTE에 속하는 미생물이 인 제거에 중요한 역할을 수행할 것으로 생각되었고 Acinetobacter, Aeromonas, Pseudomonas 등은 생물학적 인 제거에 있어서 과평가된 것으로 판단되었다.

• 한국산학기술학회논문지
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• 제19권3호
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• pp.83-89
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• 2018

구조물의 강도 저하를 유발하는 균열의 조기 탐지 및 보수는 인적, 사회적 손실을 예방할 수 있는 중요한 부분이다. 이 논문에서는 균열 탐지를 위하여 적외선 열화상 기법 중 광-적외선 열화상 기술을 이용하여 콘크리트 시편의 균열 깊이에 따른 온도 특성을 분석하였다. 시멘트 반죽을 이용하여 0, 10, 20, 40, 80 mm의 인공 균열이 있는 시편을 제작하였으며, 인공 균열 부분은 깊이를 제외한 모든 부분을 같게 생성하였다. 실험은 시편의 온도 특성을 파악하기 위하여 열원을 통해 시편을 가열한 후 균열부의 최저 온도를 비교하였다. 시편의 균열 여부에 따라 시편 표면 온도 분포가 입사 에너지의 단일, 다중 반사 때문에 다르게 변화한다는 것을 확인하였으며, 시편의 온도 분포가 정상상태에 다다를수록 균열 깊이에 따른 온도가 감소하는 경향이 뚜렷해지는 것을 확인할 수 있었다. 정규화된 온도 데이터를 통하여 이 실험에 사용된 시편은 10분 후 정상 상태에 근접하였으며, 10분 이후의 온도 데이터를 선형 회기 분석한 선형 방정식 기울기의 표준편차는 0.0005, y 절편 표준편차는 0.0038이다. 이때 정규화된 온도데이터의 표준편차는 0.01 이하로 매우 정합하며 균열 깊이에 따라 온도가 선형적으로 감소하고 있다. 이러한 결과는 균열부의 다중 반사가 발생하는 면적과 밀접한 관계가 있는 것으로 판단되며, 다양한 시편을 통해 균열부 면적과 입사 에너지의 상관관계를 분석한다면 무작위성이 높은 빛의 난반사 거동 모사에도 적용할 수 있을 것이다.

• 대한기계학회논문집B
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• 제28권3호
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• pp.265-270
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• 2004

Experiment study on a down scaled two-phase catalytic reactor is presented. As a preliminary step for the development of catalytic reactor, nano-particulate catalyst was prepared. Perovskite La$\_$0.8/Sr$\_$0.2/CoO$_3$is chosen and synthesized as a catalyst considering superior catalytic performance in reduction and oxidation process where oxygen is involved among the reagent. Reactor that has a scale of 2${\times}$10${\times}$25mm was made by machining of A1 block as a layered structure considering further extension to micro-machining. Hydrogen peroxide of 70wt% was adopted as reactant and was provided to the reactor loaded with 1.5 g of catalyst. Reactant flow rate was varied by precision pump with a range of 0.15cc/min to 17.2cc/min. Temperature distribution within reactor was recorded by 3 thermocouples and total amount of liquid product was measured. Temperature distribution and factors that affect temperature were observed and relation between temperature distribution and production rate was also analyzed. Relative time scale plays a significant role in the performance of the reactor. To obtain steady state operation, appropriate ratio of flow rate, catalyst mass and reactor geometry is required and furthermore to get more efficient production rate temperature distribution should be evenly distributed. The database obtained by the experiment will be used as a design parameter for micro reactor.

• Biomolecules & Therapeutics
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• 제5권2호
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• pp.179-186
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• 1997

The pharmacokinetics and tissue distribution of DWP20373, a novel fluoroquinolone, were examined in rats and beagle dogs after a single intravenous and oral administration. Analysis of DWP20373 in plasma, tissue, and urine was performed by both HPLC and microbiological assay. The plasma drug concentration declined biexponentially both rats and beagle dogs. In the rats, the terminal drug elimination half-life (t$_{1}$2$\beta$/) was 64 min (IV) and 57 min (PO) by bioassay, and 76 min (IV) and 77 min (PO) by HPLC. Whereas in beagle dogs, t$_{1}$2$\beta$/ was 196 min (IV) and 350 min (PO). The volume of distribution at steady-state (Vd$_{ss}$ ) was 811 ml/kg (bioassay) and 2061 ml/kg (HPLC) in rats, and 2738 ml/kg (bioassay) in beagle dogs. The total body clearance (Cl$_{t}$) of DWP20373 was 10 ml/min/kg (bioassay) and 7 ml/min/kg (HPLC) in rats, and 11 m1/min/kg (bioassay) in beagle dogs. The extent of bioavailability after oral administration was 49% (bioassay) and 67% (HPLC) in rats, and 84% (bioassay) in beagle dogs. The 24-h urinary recovery, measured by bioassay, was 2.7% after oral dosing and 5.5% after intravenous dosing in rats. Serum protein binding ratio determined at 27g/ml was 78%. This drug was also distributed in tissues in the decreasing order of liver, kidney, spleen, lung, heart, and muscle determined at 30 min after oral administration.on.

• 한국임상약학회지
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• 제1권1호
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• pp.31-36
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• 1991

Tobramycin is one of the most frequently selected agents for pharmacokinetic drug monitoring because of its narrow therapeutic index and essential role for the management of serious infections, especially gram-negative infections. Its pharmacokinetic parameters are dependent on race, sex, age, ideal body weight. disease states, and etc. Therefore, to schedule the dosing of tobramycin, the individual pharmacokinetic parameters such as half-life and volume of distribution are needed. However, these pharmacokinetic parameters have never been reported in Koreans. The purposes of this study were to evaluate the volume of distribution of tobramycin in cancer patients who had normal renal function, to compare the mean values of Vd reported in the literature, and to compare the measured half-life with the expected half-life based on ABW, LBW, and IBW, respectively. Venous blood samples were collected just before and thirty minutes after dosing during steady state. Serum tobramycin concentrations were determined by $TD_x$ (fluorescence immunoassay). IBW were measured by the method of Devine: and LBW were measured by the method of Hallynck. Creatinine clearances (CLcr) of the patients were estimated using the Cockcroft and Gault equation. Elimination rate constants (kel) were determined using the Welling and Craig equation. Infusion rate (ko), volume of distribution (Vd), and half-life $(t_{1/2})$ were determined using the Saw chuk and Zaske equation. The volume of distribution Was $27\%$ greater than the Schentag's study (0.26 vs 0.33 l/kg), but the half-life was similar to the Levy's study. The predicted half-lives based on IBW were the closest to actual half-lives (1.85 vs 2.01 hr).

• 한국환경독성학회:학술대회논문집
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• 한국환경독성학회 2003년도 춘계학술대회
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• pp.149-149
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• 2003

To understand environmental paths of the transport and accumulation of endocrine disrupting chemicals (EDCs), a single cell multimedia fate model has been constructed and evaluated. The EDCs of concern were PAHs, Organochlorine Pesticides (OCPs), PCBs, Alkyl phenols, and phthalates. An evaluation model was designed for the multimedia distribution, including air, water, soil, sediment and vegetation. This model was verified using reported values and via monitoring data. Based on collected data, the distribution trends of EDCs with respect to environmental media were analyzed. Those results have applied to the model for the prediction of the spatial and temporal distribution of EDCs in Seoul. Especially, phenol compound, phthalates, PAHs, PCBs and organochlorine pesticides were estimated and the model was verified. This model was successfully conducted to environmental media, such as air (vapor and suspended particles), soils (forest soil, bare soil, and cement-concrete covered soil), water (dissolved and suspended solids), sediment, trees (deciduous and coniferous). The discrepancies between the model prediction and the measured data are approximately within or near a factor of 10 for the PAHs of three rings through that of six rings, implying that multimedia distribution of the PAHs could be predicted with a factor of 10. Concerning about the air equilibrium may be assumed, a fugacity at steady state is similar in all environmental media. Considering the uncertainties of this model, the use of equilibrium models may be sufficient for assessing chemical fates. In this study, a suggestion was made that modeling and estimation of chemicals in environmental multimedia be rigorously evaluated using the measured flux data. In addition, these data should be obtained, for example, from the precise and standardized inventory of the target chemicals. The model (EDC Seoul) will be refined in an on-going research effort and will be used to support decision-making concerning the management of EDCs.