• Fashion & Textile Research Journal
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• v.23 no.4
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• pp.423-438
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• 2021

This study compared and analyzed the direction of Louis Vuitton creative directors Kim Jones and Virgil Abloh. Accordingly, 485 photos(251 Kim Jones, 234 Virgil Abloh) were collected. For data analysis, statistical and content analyses were combined. First, as for the overall design characteristics of creative director Kim Jones, complex colors, colorful barrels, tone-in-tone color schemes, H-line, plain fabrics, soft materials, heterogeneous material combinations, casual style. Second, as for the overall design characteristics of creative director Virgil Abloh, achromatic color, colorful tone, tone-on-tone color scheme, I-line, plain fabric, soft material, similar material combination, casual style. There were significant differences in color, tone, color scheme, silhouette, pattern, material type, material combination, fashion image, detail, trimming, top and bottom that differed in the creative directors' design direction. Therefore, it appears that Kim Jones has been directing the luxurious and unique men's wear through H-line, coat and slim pants, colorful color combination, soft material, heterogeneous material combination, plain fabric, and chic active sensibility. Meanwhile, Virgil Abloh is directing men's wear in a loose and trendy street mood through the I-line, jacket and wide pants, achromatic color, soft material, plain fabric, similar material combinations, and soft and sophisticated modern sensibility.

• Journal of Convergence for Information Technology
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• v.11 no.10
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• pp.322-331
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• 2021

This study attempted to identify the multi-cultural acceptance level of freshmen in nursing colleges and to analyze the factors influencing it. For the research method, data were collected from 410 first-year nursing students at K University in W City through a questionnaire from March 1 to 28, 2021, and frequency, reliability analysis, t-test, ANOVA, correlation, and multiple regression were conducted using the open-source statistical package R. As a result of the study, the multi-cultural acceptance level of freshman in nursing colleges averaged 77.36 points, indicating that they have a slightly higher multi-cultural acceptance capacity, and as a result of analyzing the influence of multi-cultural acceptance related factors, Korean recognition requirements(𝛽=0.34, p<.001), perceived threat recognition for migrants (𝛽=0.29, p<.001), Experience in multi-cultural education(𝛽=0.14, p<.001), Recognition of the appropriate age for multi-cultural education (𝛽=0.20, p<.001) was statistically significant. According to results, it is necessary to develop and actively utilize regular curriculum and programs related to multi-culturalism for nursing students.

• Korean Journal of Clinical Pharmacy
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• v.31 no.3
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• pp.188-197
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• 2021

Objective: PD-1 inhibitors have demonstrated improved health outcomes in cancer patients. PD-1 inhibitors are well-tolerated and associated with immune-related adverse events. The objectives of this study are to analyze use patterns of PD-1 inhibitors in patients with cancer and to investigate the incidence of thyroid-related adverse reactions in patients treated with PD-1 inhibitors. Methods: The study included patients who had been administered PD-1 inhibitors (either nivolumab or pembrolizumab) at the Samsung Medical Center between October 1, 2016 and June 30, 2017. Data was collected from electronic medical records and tested using Mann-Whitney tests and Chi-Square tests for statistical significance. Associations between PD-1 inhibitors and incidence of adverse events were tested using Cox regression for age, gender, BMI, ECOG PS and medication. Results: Two hundred fifteen patients were identified as eligible for analyses. Thyroid-related adverse events occurred in 20% of patients (n=43). Thyroid function tests (TFTs) was performed in 109 patients (50.7%). Positive results of PD-L1 testing were found in 53.2% of the 94 patients who had the test. Approved doses of nivolumab (3 m/kg) and pembrolizumab (200 mg) were administered in 70.4% and 53% of patients, respectively. The analysis of risk factor of thyroid-related adverse reaction did not show statistically significant differences (Cox regression). Conclusion: Thyroid-related adverse events are common in patients treated with PD-1 inhibitors and hypothyroidism is the most frequent adverse reaction. Routine TFTs monitoring is strongly recommended to evaluate thyroid function in real-world clinical practice.

• Composites Research
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• v.34 no.5
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• pp.330-336
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• 2021

Alumina powder is one of the widely used materials for industry, but there is a problem that the strength of the product changes depending on the powder packing state. To solve the above problem, previous studies have been conducted to increase the particle packing efficiency, but most of the existing studies analyzed the packing characteristics of millimeter-scale particles, so the physical properties are different from those of the micrometer scale. It is difficult to apply to the micrometer scale. In this paper, a three-step experiment was performed using a statistical method to increase packing using micrometer-scale alumina powder. First, a size combination with high packing and a mixing ratio were selected using the mixture test design method, and an appropriate excitation frequency was selected by analyzing the height change according to the frequency change in the vibration test apparatus. Finally, an alumina powder packing experiment was performed based on the experimental results mentioned above. As a result, it was confirmed that the maximum height variation was 42% higher than the maximum value of the 155 measurements performed when selecting the packing size combination. It is thought that this study will serve as basic data for processing and packing research using fine powder.

• Korean Journal of Clinical Pharmacy
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• v.31 no.3
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• pp.198-204
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• 2021

Background: Cardiovascular (CV) disease is known as one of the major causes of death from disease worldwide. Statin therapy plays a pivotal role in atherosclerotic cardiovascular disease (ASCVD) lowering the LDL-cholesterol level effectively. The purpose of this study was to evaluate the association of the intensity of statin therapy in adult patients of Korea and the risk of ASCVD of the patient group. Methods: We used data from sample of patients from the Health Insurance Review and Assessment Service (HIRA-NPS-2018). We analyzed the patterns of prescribing statins including types of statin, statin intensity, and number of patients with ASCVD or risk of ASCVD. Results: 155,512 patients were included in the analysis, and 27,950 patients (18.0%) was over 75 years. High-intensity statin usage was increased in ASCVD patients compared with the low-intensity statin use. The OR (odds ratio) of high-intensity statin were increased in myocardial infarction patients compared with low-intensity statin use showing the highest OR; 12.40 (95% CI; 9.48-16.22). At patient groups of angina, ischemic heart disease and carotid disease, high-intensity statin prescription rate was increased compared with low-intensity statin. However, there was no statistical significance between both statin prescription rates in patients of peripheral arterial disease, abdominal aneurysm, diabetic mellitus and atherosclerosis. Conclusion: The statin prescription rate showed intensity increasing tendency according to the risk of ASCVD. More aggressive statin therapy might be beneficial for the ASCVD patients based on the recent guidelines of dyslipidemia.

• Journal of dental hygiene science
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• v.21 no.3
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• pp.185-197
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• 2021

Background: This study aimed at investigating the meal regularity, health, and oral health habits of single Korean households to understand the impact of these factors on the risk of metabolic syndrome, in addition to preventing and managing metabolic syndrome. Methods: Using raw data from the 8th Korea National Health and Nutrition Examination Survey (2019), 274 study subjects, aged 19 to 64, were selected primarily from single adult households. Complex sample statistical analysis was performed using the Predictive Analytics Software Statistics ver. 18.0 program. Results: Regarding the meal regularity in single-person households in Korea, the younger group outperformed the middle-aged group, and those who drank more than once a month performed better than those who drank less than once a month. In terms of oral health, regardless of the age and the income level, participants who ate three meals a day had a higher rate of speech problems and chewing difficulties than those who ate irregularly or regularly on a regular day. Factors influencing the risk of developing metabolic syndrome were age, speech problems, and frequency of toothbrushing. Compared to the younger group, there were 0.361 times more people in the middle-aged group; and compared to those without speech problems, there were 1.161 more people with speech problem. Compared to those who tooth brushed more than four times a day, there were 1.284 more people who tooth brushed 2 to 3 times a day and there were 5.673 times more people who tooth brushed less than once. Conclusion: Based on the study results, it is necessary to implement a program that can plan and apply customized management measures and prevent metabolic syndrome by improving and correcting the health and oral health behaviors of single-person households in Korea. Therefore, active mediation measures, such as support and publicity at the local or national level, should be planned.

• Genomics & Informatics
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• v.19 no.1
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• pp.11.1-11.8
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• 2021

For the novel coronavirus disease 2019 (COVID-19), predictive modeling, in the literature, uses broadly susceptible exposed infected recoverd (SEIR)/SIR, agent-based, curve-fitting models. Governments and legislative bodies rely on insights from prediction models to suggest new policies and to assess the effectiveness of enforced policies. Therefore, access to accurate outbreak prediction models is essential to obtain insights into the likely spread and consequences of infectious diseases. The objective of this study is to predict the future COVID-19 situation of Korea. Here, we employed 5 models for this analysis; SEIR, local linear regression (LLR), negative binomial (NB) regression, segment Poisson, deep-learning based long short-term memory models (LSTM) and tree based gradient boosting machine (GBM). After prediction, model performance comparison was evelauated using relative mean squared errors (RMSE) for two sets of train (January 20, 2020-December 31, 2020 and January 20, 2020-January 31, 2021) and testing data (January 1, 2021-February 28, 2021 and February 1, 2021-February 28, 2021) . Except for segmented Poisson model, the other models predicted a decline in the daily confirmed cases in the country for the coming future. RMSE values' comparison showed that LLR, GBM, SEIR, NB, and LSTM respectively, performed well in the forecasting of the pandemic situation of the country. A good understanding of the epidemic dynamics would greatly enhance the control and prevention of COVID-19 and other infectious diseases. Therefore, with increasing daily confirmed cases since this year, these results could help in the pandemic response by informing decisions about planning, resource allocation, and decision concerning social distancing policies.

• Journal of Navigation and Port Research
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• v.45 no.3
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• pp.165-172
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• 2021

Breaking wave is one of the important design factors in the design of coastal and port structures as they are directly related to various physical phenomena occurring on the coast, such as onshore currents, sediment transport, shock wave pressure, and energy dissipation. Due to the inherent complexity of the breaking wave, many empirical formulas have been proposed to predict breaker indices such as wave breaking height and breaking depth using hydraulic models. However, the existing empirical equations for breaker indices mainly were proposed via statistical analysis of experimental data under the assumption of a specific equation. In this study, a new Munk-type empirical equation was proposed to predict the height of breaking waves based on a representative linear supervised machine learning technique with high predictive performance in various research fields related to regression or classification challenges. Although the newly proposed breaker height formula was a simple polynomial equation, its predictive performance was comparable to that of the currently available empirical formula.

• Neurospine
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• v.15 no.4
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• pp.376-382
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• 2018

Objective: The purpose of this study was to evaluate factors associated with inpatient admission following 2-level cervical disc arthroplasty (CDA). A secondary aim was to compare outcomes between those treated on an inpatient versus outpatient basis. Methods: Using data from the American College of Surgeons National Surgical Quality Improvement Program database, multivariate logistic regression analysis was used to assess the independent effect of each variable on inpatient or outpatient selection for surgery. Statistical significance was defined by p-values <0.05. The factors considered were age, sex, body mass index (BMI), smoking status, American Society of Anesthesiologists physical status classification, and comorbidities including hypertension, diabetes, history of dyspnea or chronic obstructive pulmonary disease, previous cardiac intervention or surgery, steroid usage, and history of bleeding. In addition, whether the operation was performed by an orthopedic or neurosurgical specialist was analyzed. Results: The number of 2-level CDA procedures increased from 6 cases reported in 2014 to 142 in 2016, although a statistically significant increase in the number of outpatient cases performed was not seen (p=0.2). The factors found to be significantly associated with inpatient status following surgery were BMI (p=0.019) and diabetes mellitus requiring insulin (p=0.043). There were no significant differences in complication and readmission rates between the inpatient and outpatient groups. Conclusion: Patients undergoing inpatient 2-level CDA had significantly higher rates of obesity and diabetes requiring insulin than did patients undergoing the same procedure in the outpatient setting. With no difference in complication or readmission rates, 2-level CDA may be considered safe in the outpatient setting in appropriately selected patients.

• Journal of Digital Convergence
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• v.17 no.3
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• pp.463-471
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• 2019

The purpose of this study was to investigate the effect of muscle imbalance on motion of back squat. The isokinetic muscle strength of the 8 subjects was recorded for the knee flexion/extension by the cybex 770 dynamometer. Each subject performed 3 back squats with the long barbell with an intensity of 25% body weight(BW), 50%BW, 100%BW, 125%BW. During the back squat through the recorded kinematic data the subjects' maximum flexion and extension knee angle, center of mass displacement and V-COP were calculated for evaluation of the stability of the movement. For the statistical analysis independent t-test was used. Knee flexion angle and COM displacement are dominated by the reciprocal muscle ratio. V-COP factor was dominated by bilateral extension deficit. Based on the results we can know that as the intensity of the squat increased to a level control was difficult because the muscles' imbalance influenced the movement.