• Title/Summary/Keyword: statistical assessment

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Impact of Tumor Length on Survival for Patients with Resected Esophageal Cancer

  • Mirinezhad, Seyed Kazem;Jangjoo, Amir Ghasemi;Seyednejad, Farshad;Naseri, Ali Reza;Mohammadzadeh, Mohammad;Nasiri, Behnam;Eftekharsadat, Amir Taher;Farhang, Sara;Somi, Mohammad Hossein
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.2
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    • pp.691-694
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    • 2014
  • Background: Tumor length in patients with esophageal cancer (EC) has recently received great attention. However, its prognostic role for EC is controversial. The purpose of our study was to characterize the prognostic value of tumor length in EC patients and offer the optimum cut-off point of tumor length by reliable statistical methods. Materials and Methods: A retrospective analysis was conducted on 71 consecutive patients with EC who underwent surgery. ROC curve analysis was used to determine the optimal cut-off point for tumor length, measured with a handheld ruler after formalin fixation. Correlations between tumor length and other factors were surveyed, and overall survival (OS) rates were compared between the two groups. Potential prognostic factors were evaluated by univariate Kaplan-Meier survival analysis. A P value less than 0.05 was considered significant. Results: There were a total of 71 patients, with a male/female divide of 43/28 and a median age of 59. Characteristics were as follows: squamous/adenocarcinoma, 65/6; median tumor length, 4 (0.9-10); cut-off point for tumor length, 4cm. Univariate analysis prognostic factors were tumor length and modality of therapy. One, three and five year OS rates were 84, 43 and 43% for tumors with ${\leq}4cm$ length, whereas the rates were 75, 9 and 0% for tumors >4 cm. There was a significant association between tumor length and age, sex, weight loss, tumor site, histology, T and N scores, differentiation, stage, modality of therapy and longitudinal margin involvement. Conclusions: Future studies for modification of the EC staging system might consider tumor length too as it is an important prognostic factor. Further assessment with larger prospective datasets and practical methods (such as endoscopy) is needed to establish an optimal cut-off point for tumor length.

Comparative Assessment of Corporate Philanthropy by the IPA Method: Service and Manufacturing Industries (IPA기법을 활용한 기업의 사회공헌활동 비교 평가: 서비스업 및 제조업을 중심으로)

  • Ko, Jeong-Yong;Park, Hyeon-Suk
    • Journal of Distribution Science
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    • v.13 no.4
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    • pp.89-98
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    • 2015
  • Purpose - In today's globalized and modern business environment, corporate social responsibility (CSR) activities are considered to be essential for the sustainable development of enterprises. In addition, the corporate philanthropy that is related to CSR practices, as well as their being capable of reducing the anti-corporate sentiment of people have facilitated a qualitative forward leap into the quantitative growth phase. This study aims to undertake a comparative evaluation of corporate philanthropy through the Importance-Performance Analysis (IPA) method focusing on service and manufacturing industries, and to eventually determine a differentiated approach that is needed for corporate philanthropy. Research design, data, and methodology - The survey responses were collected through online research on specialized companies from consumers nationwide who were aged from 20 to 60 and who are aware of corporate philanthropy. A total of 408 sheets of questionnaire survey were used. Frequency analysis was undertaken in this study. The interviewees had demographic characteristics of gender: 206 males (50.5%) and 202 females (49.5%). They also had demographic characteristics of age: 82 people were over 20 (20.1%), 96 over 30 (23.5%), 105 over 40 (25.7%), and 125 over 50 (30.7%) years of age. The distribution of interviewees' residences is as follows: 154 persons (37.7%) in the Special City, 102 persons (25.0%) in the Metropolitan City, and 152 persons (37.3%) in the Provincial Region. The interviewees have been working for the following companies: 34 persons (8.3%) in LG Display, 80 (19.6%) in KT&G, 49 (12.0%) in Amore Pacific, 42 (10.3%) in KIA Motors, 47 (11.5%) in SBS, 52 (12.8%) in Shinhan Bank, 86 (21.1%) in Asiana Airlines, and 18 (4.4%) in Hyundai Department Store. We applied the paired t-test for the IPA analysis. PASW Statistics 18 was used for statistical analysis. Results - The results of IPA analysis indicated that the importance and performance degrees in both manufacturing and service industries were significantly different. Major empirical results showed that, in consumer, social, economic, philanthropic, and environmental dimensions, in the sub-factors of philanthropy activities in both manufacturing and service industries, the importance degree was found to be higher than performance degree. Further, the average difference between importance degree and performance degree by the sub-factors of philanthropy activities. On the other hand, the average difference of environmental dimension was found to be highest in both service and manufacturing industries. Thus, while consumers consider the philanthropy activities of the environmental dimension as most important, actual companies treat performance of philanthropy activities of the environmental dimension insufficiently or negligibly to some degree. Conclusions - The differentiated approach method that is required for corporate philanthropy may be proposed to uplift corporate accomplishments by analyzing the IPA of the attributes of the sub-factors of corporate philanthropy. This is, to an extent, insufficient in the existing studies related to the use of the IPA technique, and it shows the items that are to be conducted intensively.

Ability of Biochemical Parameters to Distinguish between Bile Duct Cancer and Gall Bladder Stones - A Case Control Study in a Tertiary Care Hospital of Pokhara Valley

  • Yadav, Shambhu Kumar;Mittal, Ankush;Sapkota, Kumar;Gupta, Satrudhan Prasad;Sathian, Brijesh
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.2
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    • pp.817-819
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    • 2013
  • Background: The present study was designed to comparatively assess alteration of biochemical parameters in bile duct cancer and gall stone disease. Materials and Methods: A hospital based case-control study was carried out in the Department of Biochemistry of Manipal Teaching Hospital, Pokhara, Nepal between $1^{st}$ January 2010 and $31^{st}$ December 2012. The variables collected were age, gender, serum total cholesterol, total bilirubin, AST, ALT, serum alkaline phosphatase, albumin and hemoglobin. One way ANOVA was used to examine the statistical significance of differences between groups. A post-hoc LSD test was applied for the comparison of means of control versus case groups. A p-value of <0.05 (two-tailed) was considered significant. Results: The mean age of cases and controls was $53.2{\pm}21.2$ years. The levels of serum cholesterol were higher in cases of cancer $192.5{\pm}21.5$ mg/dl in comparison to stone cases $168.7{\pm}16.1$ mg/dl (p value: 0.0001). The total bilirubin showed the marked difference in cases of cancer $7.6{\pm}3.2$ mg/dl in comparison to stone cases $2.5{\pm}0.8$ mg/dl of bile duct. There was discernible divergence in values of alkaline phosphatase in cases of cancer $251.5{\pm}20.1$ IU/l when compared to stone cases $173.2{\pm}12.6$ IU/l of bile duct. In contrast, there was no apparent deviation in values of aspartate transaminases and alanine transaminases in cases of cancer $59.1{\pm}8.9$ IU/l and $105.5{\pm}26.5$ IU/l when compared to stone cases $56.9{\pm}7.9$ IU/l and $84.5{\pm}13.5$ IU/l respectively. Conclusions: LFT analysis for pre-operative assessment was a good predictive marker in setting apart bile duct cancer and gall bladder stone.

Morphologic and positional assessment of temporomandibular joint disk in facial asymmetric patients by magnetic resonance imaging (자기 공명 영상을 이용한 안면비대칭환자의 측두하악관절원반의 형태와 위치에 관한 연구)

  • Zou, Bingshuang;Kim, Tae-Woo;Choi, Soon-Chul
    • The korean journal of orthodontics
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    • v.35 no.5 s.112
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    • pp.398-407
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    • 2005
  • The present study was conducted to examine the morphometrics and function of the disk on both sides among patients with facial asymmetry (FA) and to elucidate plausible correlations between internal derangement (ID) and FA. The sample was composed of 10 males and 27 females with FA. The disk status of all subjects was evaluated by bilateral high resolution magnetic resonance scans in the sagittal (closed and open) and coronal (closed) planes. Five types of disk displacement were identified accordingly. The disk function was diagnosed as normal disk function, disk displacement with reduction, and disk displacement without reduction. The disk shape on sagittal MRI in closed position was classified as bi-concave, biplanar, funnel/hemiconvex, and deformed. The disk position, translation and rotation were also measured. The difference between the shifted side and non-shifted side was analyzed by statistical analysis. Approximately $70\%$ of the patients in the present study showed unilateral or bilateral ID. It was found that anterior disk displacements (ADD), especially rotational ADD, occurred more frequently in the shifted side, while normal disk position was observed mainly in the non-shifted side (p<0.01). The disk of the shifted side showed significantly deformed configuration and inferior-anterior disk position. However, the disk of the non-deviated side showed hyper-mobility during jaw opening movement. These results demonstrate that in FA patients, the disks status of the shifted side is different from that of the non-shifted side, a phenomenon that could be correlated to facial asymmetry.

Decision of GIS Optimum Grid on Applying Distributed Rainfall-Runoff Model with Radar Resolution (레이더 자료의 해상도를 고려한 분포형 강우-유출 모형의 GIS 자료 최적 격자의 결정)

  • Kim, Yon-Soo;Chang, Kwon-Hee;Kim, Byung-Sik;Kim, Hung-Soo
    • Journal of Wetlands Research
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    • v.13 no.1
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    • pp.105-116
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    • 2011
  • Changes in climate have largely increased concentrated heavy rainfall, which in turn is causing enormous damages to humans and properties. Therefore, the exact relationship and the spatial variability analysis of hydrometeorological elements and characteristic factors is critical elements to reduce the uncertainty in rainfall -runoff model. In this study, radar rainfall grid resolution and grid resolution depending on the topographic factor in rainfall - runoff models were how to respond. In this study, semi-distribution of rainfall-runoff model using the model ModClark of Inje, Gangwon Naerin watershed was used as Gwangdeok RADAR data. The completed ModClark model was calibrated for use DEM of cell size of 30m, 150m, 250m, 350m was chosen for the application, and runoff simulated by the RADAR rainfall data of 500m, 1km, 2km, 5km, 10km from 14 to 17 on July, 2006. According to the resolution of each grid, in order to compare simulation results, the runoff hydrograph has been made and the runoff has also been simulated. As a result, it was highly runoff simulation if the cell size is DEM 30m~150m, RADAR rainfall 500m~2km for peak flow and runoff volume. In the statistical analysis results, if every DEM cell size are 500m and if RADAR rainfall cell size is 30m, relevance of model was higher. Result of sensitivity assessment, high index DEM give effect to result of distributed model. Recently, rainfall -runoff analysis is used lumped model to distributed model. So, this study is expected to make use of the efficiently decision criteria for configurated models.

Assessment of Statistical Property of Drought in Korea using SPI and PDSI (SPI와 PDSI로 본 한반도 가뭄의 통계학적 특성분석)

  • Seo, Ji-Won;Kim, Chang-Joo;Lee, Joo-Heon
    • Proceedings of the Korea Water Resources Association Conference
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    • 2011.05a
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    • pp.28-28
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    • 2011
  • 치수는 고대국가로부터 현재의 국가에 이르기까지 중차대한 국가사업이다. 근대를 지나면서 산업화가 가속화되었고 수자원의 사용과 관리는 더욱 세분화 되었다. 또한 수자원의 사용과 관리에 앞서 기후와 밀접한 관계가 있는 수자원의 물리적 특성을 분석하는 연구가 활발히 이루어지고 있다. 최근 우리나라도 급격한 산업화로 인한 환경파괴와 지구온난화로 인한 강수의 편중이 더욱 심해지고 있다. 즉, 한반도도 전 세계가 직면한 기후변화로 인한 자연재해로 부터 안전하지 않다는 것을 의미한다. 특히 수자원을 관리함에 있어 가뭄의 경우에는 장기적으로 진행되는 경우가 많고 피해 규모와 복구 등도 가뭄의 진행 기간과 밀접한 관계를 가지므로 적극적인 대비가 필요하다. 따라서 가뭄을 연구함에 앞서 과거 한반도의 가뭄의 경향성 및 주기성 같은 특성을 분석할 수 있는 연구가 수반되어야 할 것으로 사료된다. 이에 따라 본 논문에서는 과거 한반도 가뭄 사상의 특성분석을 위해 대표 가뭄지수로 SPI(Standardized Precipitation Index)와 PDSI(Palmer Drought Severity Index)를 선정하여 우리나라 전역에 위치한 총 59개 기상관측소의 1980년~2009년까지의 기상자료를 수집하여 유역별 월평균 가뭄지수를 산정하였다. 또한 이를 이용하여 가뭄발생의 경향성 및 주기성을 중심으로 과거한반도 가뭄의 통계학적 특성분석을 실시하였다. 각 지수의 경향성을 분석한 결과, SPI3와 SPI6는 봄과 겨울에는 가뭄이 심화되는 경향을 보였고 여름철에는 가뭄이 완화되는 경향을 보였다. 반면 SPI12의 경우는 섬진강과 영산강은 유의하지는 않으나 전 기간에 걸쳐 가뭄이 심화되는 경향을 보였고 한강, 낙동강, 금강유역은 가뭄이 완화되는 것으로 나타났다. PDSI의 경우에는 SPI와는 반대로 섬진강과 영산강은 전 기간에 걸쳐 가뭄이 완화되는 경향을 보였고 한강, 낙동강, 금강유역은 유의한 수준에서 가뭄이 심화되는 경향을 보임으로써, SPI와 PDSI에 의한 가뭄평가 경향성이 유역별로 다소 다르게 나타나는 것을 확인할 수 있었다. 한편, 각 유역의 주기성을 분석한 결과로는 모든 유역에서 1년~3년 또는 6년 이하의 주기성을 나타냈으며, SPI의 경우 지속기간이 길어질수록 6년 이상의 저빈도 주기성을 나타냈고, SPI3는 짧게는 1년 미만의 고빈도 주기를 보이는 경우도 있었으며, SPI6와 SPI12는 4년~6년 주기를 나타냈다. 또한 PDSI도 마찬가지로 6년 내외의 장주기를 보였다. 특히 유역별로 분석할 경우 남부지역의 가뭄발생 주기가 중부지역보다 길게 나타나는 성향을 보였다. 그리고 SPI와 PDSI, 두 가뭄지수의 공통주기를 분석한 결과에서는 상관관계가 적은 것으로 확인 되었다.

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Reproducibility of Nutrient Intake Estimated by Three-Day 24-Hour Dietary Recall of Middle-Aged Subjects for 6 Month Intervals (자기기록식 3일간의 24시간 회상법의 신뢰도 연구 -서울지역 중년 자원자를 대상으로-)

  • 이미숙;우미경;김성애;오세인;곽충실
    • Korean Journal of Community Nutrition
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    • v.8 no.4
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    • pp.603-609
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    • 2003
  • This study examined the reproducibility of nutrient intakes estimated by the 24-hour recall method in a prospective cohort study (Longitudinal study of aging and health monitoring of Korean elderly) of middle-aged volunteer subjects (42 males and 49 females) in the Seoul area. The three-day 24-hour recall was administered twice at an interval of approximately 6 months. The first data were collected and a corrective procedure was performed by interviewing of the subjects and a trained dietitian. The second data were collected by mail from the subjects without the performance of any corrective procedure. The mean age of the subjects was 53.5 $\pm$ 9.6 for the males and 52.2 $\pm$ 8.9 for the females. The subjects who had above college education were 95% in the case of the males and 60% in the case of the females. The characteristics of the male subjects in this study were that they were highly educated and held professional jobs and were from the middle or upper class. Comparing the first and second 24-hour recall data, the second data showed relatively lower intakes of all nutrients, except vitamin A, vitamin Bi and cholesterol. There was no difference in the nutrients of the first and the second data with respect to vitamin A, vitamin B$_1$ and cholesterol in the males and calcium, iron, sodium, vitamin A, vitamin B$_1$, vitamin B$_2$ and cholesterol in the females. This data may indicate that the 24 hour retail method without a dietitian's help may result in lower reporting of the subject's intakes. The men had a tendency to remember less than the women. Pearson's correlation coefficients with unadjusted nutrient intakes values were ranged from 0.24 to 0.66. When energy intake was adjusted, there was a slight increase (from 0.26 to 0.71). Intra-class correlation coefficients with nutrient-unadjusted values ranged from 0.22 to 0.66, and the energy-adjusted values were ranged from 0.23 to 0.69. The weighted Kappa statistical values ranged from 0.10 to 0.40. On the average,46.3% of the subjects who were found in the lowest quartile of the nutrient intake levels based on the first 24-hour recall, were in the lowest quartile based on the second 24-hour recall. Therefore, there was a low reproducibility between the first and the second 24-hour recall. We should examine the factors influencing low reproducibility. Also, strategies should be developed to maximize the reliability of the assessment, with regard to portion-size training and telephone validation. (Korean J Community Nutrition 8(4) : 603∼609, 2003)

Assessment of Hydrogeochemical Characteristics and Contaminant Dispersion of Aquifer around Keumsan Municipal Landfill (금산 매립장 주변 대수층의 수리지화학적 특성 및 오염 확산 평가)

  • Oh, In-Suk;Ko, Kyung-Seok;Kong, In-Chul;Ku, Min-Ho
    • Economic and Environmental Geology
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    • v.41 no.6
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    • pp.657-672
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    • 2008
  • The purposes of this study are to investigate the hydrogeochemical characteristics of groundwaters around Keumsan municipal landfill, and to evaluate the contaminant dispersion from the landfill and its environmental impact. To achieve these goals, groundwater quality logging, hydrochemical analysis, multivariate statistical analysis, and contaminant transport modeling were performed. The water quality logging indicated a leaking from the landfill at the depth of 4-12m around a leachate sump. Electrical conductivity data indicated that groundwaters within 70-100m from landfill were affected by the landfill leakage. Principal components 1 and 2 obtained from principal components analysis (PCA) reflect the influence of leachate and the characteristics of aquifer media, respectively. The results of principal component analysis also indicated the natural attenuation processes such as cation exchange, sorption, and microbial biodegradation. The modeling results showed that groundwater flow westward along a valley from the landfill and contaminants transport accordingly.

Association between Myofascial Pain Syndrome and the Assessment of Pain and the related Function tests in female telephone directory assistance operators using VDT (VDT 사용 여성 전화교환원들의 근막동통증후군과 동통 및 기능평가 검사와의 관련성)

  • Roh, Sang-Chul;Lee, Soo-Jin;Song, Jae-Cheol;Park, Hung-Bae
    • Journal of Preventive Medicine and Public Health
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    • v.30 no.4 s.59
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    • pp.779-790
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    • 1997
  • The Association between myofascial pain syndrome and some tests was assessed in a cross-sectional study of 904 female telephone operators using video display terminals(VDTs). 105 cases were diagnosed as Myofascial pain syndrome with symptom questionnaire, laboratory examination and physician's physical examination and 550 controls were defined to show only musculoskeletal symptoms using NIOSH symptom criteria. Data on demographics, musculoskeletal symptom and visual analogue scale(VAS) were obtained by questionnaire. Anthropometric measurements, pressure pain threshold, Grip & Pinch strength and laboratory test were conducted. No significant difference between case and control at comparing of demographics, occupational history and body measurements were observed. But, Grip strength, pressure pain threshold and VAS showed the statistical difference between case and controt. Age, pressure pain threshold of Rt. Upper trapezius and VAS were associated with myofascial pain syndrome in multivariate logistic regression analysis. This results suggest that, to diagnose of myofascial pain syndrome, the consideration of the objective aspects among patients' subjective symptom complaints through the VAS and pressure pain threshold is required.

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Comparative Hepatotoxicity Assessment of Cadmium and Nickel with Isolated Perfused Rat Liver(IPRL) (적출간 관류법을 이용한 카드뮴과 니켈의 간독성 비교)

  • Cha, Bong-Suk;Chang, Sei-Jin;Lee, Jung-Woo;Wang, Seung-Jun
    • Journal of Preventive Medicine and Public Health
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    • v.33 no.1
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    • pp.117-124
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    • 2000
  • Objectives : It is the objective of this study to compare hepatotoxicity of nickel chloride and cadmium chloride with each other through IPRL(Isolated Perfused Rat Liver) method. Methods : Biochemical indicator of hepatic function such as AST(aspartate aminotransferase), ALT(alanine aminotransferase), LDH(lactate dehydrogenase) and perfusion flow rate were used as the indicator of hepatotoxicity. Oxygen consumption rate were used as vability indicator. $300({\pm}50)g$ - weighted rats were allocated randomly to each group($0{\mu}M,\;50{\mu}M,\;200{\mu}M\;NiCl_2\;and\;CdCl_2$ exposure) by 5, totally 25. After Krebs-Ringer bicarbonate butler solution flowed into the penal vein and passed the liver cell, it flowed out of vena cava. Liver was administered with each $NiCl_2\;and\;CdCl_2$ of each concentration and observed with buffer solution sampling time. Butler which got out of liver was sampled and then biochemical indicator of hepatotoxicity was measured. Results : AST, ALT, and LDH in buffer increased with sampling time much more in $CdCl_2$ exposure group than $NiCl_2$ exposure group in both 50 and $200{\mu}M$ and statistical significance w3s verified with 2-way repeated ANOVA. Viability was decreased more and more in all substances during passed time. Conclusions : It is inferred that $CdCl_2$ has stronger hepatotoxicity than $NiCl_2$. IPRL method would be used widely for acute hepatotoxicity when considerating the benefit of it.

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