• Title/Summary/Keyword: statistic technique

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Development of Model Plans in Three Dimensional Conformal Radiotherapy for Brain Tumors (뇌종양 환자의 3차원 입체조형 치료를 위한 뇌내 주요 부위의 모델치료계획의 개발)

  • Pyo Hongryull;Lee Sanghoon;Kim GwiEon;Keum Kichang;Chang Sekyung;Suh Chang-Ok
    • Radiation Oncology Journal
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    • v.20 no.1
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    • pp.1-16
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    • 2002
  • Purpose : Three dimensional conformal radiotherapy planning is being used widely for the treatment of patients with brain tumor. However, it takes much time to develop an optimal treatment plan, therefore, it is difficult to apply this technique to all patients. To increase the efficiency of this technique, we need to develop standard radiotherapy plant for each site of the brain. Therefore we developed several 3 dimensional conformal radiotherapy plans (3D plans) for tumors at each site of brain, compared them with each other, and with 2 dimensional radiotherapy plans. Finally model plans for each site of the brain were decide. Materials and Methods : Imaginary tumors, with sizes commonly observed in the clinic, were designed for each site of the brain and drawn on CT images. The planning target volumes (PTVs) were as follows; temporal $tumor-5.7\times8.2\times7.6\;cm$, suprasellar $tumor-3\times4\times4.1\;cm$, thalamic $tumor-3.1\times5.9\times3.7\;cm$, frontoparietal $tumor-5.5\times7\times5.5\;cm$, and occipitoparietal $tumor-5\times5.5\times5\;cm$. Plans using paralled opposed 2 portals and/or 3 portals including fronto-vertex and 2 lateral fields were developed manually as the conventional 2D plans, and 3D noncoplanar conformal plans were developed using beam's eye view and the automatic block drawing tool. Total tumor dose was 54 Gy for a suprasellar tumor, 59.4 Gy and 72 Gy for the other tumors. All dose plans (including 2D plans) were calculated using 3D plan software. Developed plans were compared with each other using dose-volume histograms (DVH), normal tissue complication probabilities (NTCP) and variable dose statistic values (minimum, maximum and mean dose, D5, V83, V85 and V95). Finally a best radiotherapy plan for each site of brain was selected. Results : 1) Temporal tumor; NTCPs and DVHs of the normal tissue of all 3D plans were superior to 2D plans and this trend was more definite when total dose was escalated to 72 Gy (NTCPs of normal brain 2D $plans:27\%,\;8\%\rightarrow\;3D\;plans:1\%,\;1\%$). Various dose statistic values did not show any consistent trend. A 3D plan using 3 noncoplanar portals was selected as a model radiotherapy plan. 2) Suprasellar tumor; NTCPs of all 3D plans and 2D plans did not show significant difference because the total dose of this tumor was only 54 Gy. DVHs of normal brain and brainstem were significantly different for different plans. D5, V85, V95 and mean values showed some consistent trend that was compatible with DVH. All 3D plans were superior to 2D plans even when 3 portals (fronto-vertex and 2 lateral fields) were used for 2D plans. A 3D plan using 7 portals was worse than plans using fewer portals. A 3D plan using 5 noncoplanar portals was selected as a model plan. 3) Thalamic tumor; NTCPs of all 3D plans were lower than the 2D plans when the total dose was elevated to 72 Gy. DVHs of normal tissues showed similar results. V83, V85, V95 showed some consistent differences between plans but not between 3D plans. 3D plans using 5 noncoplanar portals were selected as a model plan. 4) Parietal (fronto- and occipito-) tumors; all NTCPs of the normal brain in 3D plans were lower than in 2D plans. DVH also showed the same results. V83, V85, V95 showed consistent trends with NTCP and DVH. 3D plans using 5 portals for frontoparietal tumor and 6 portals for occipitoparietal tumor were selected as model plans. Conclusion : NTCP and DVH showed reasonable differences between plans and were through to be useful for comparing plans. All 3D plans were superior to 2D plans. Best 3D plans were selected for tumors in each site of brain using NTCP, DVH and finally by the planner's decision.

A Statistical Prediction Model of Speakers' Intentions in a Goal-Oriented Dialogue (목적지향 대화에서 화자 의도의 통계적 예측 모델)

  • Kim, Dong-Hyun;Kim, Hark-Soo;Seo, Jung-Yun
    • Journal of KIISE:Software and Applications
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    • v.35 no.9
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    • pp.554-561
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    • 2008
  • Prediction technique of user's intention can be used as a post-processing method for reducing the search space of an automatic speech recognizer. Prediction technique of system's intention can be used as a pre-processing method for generating a flexible sentence. To satisfy these practical needs, we propose a statistical model to predict speakers' intentions that are generalized into pairs of a speech act and a concept sequence. Contrary to the previous model using simple n-gram statistic of speech acts, the proposed model represents a dialogue history of a current utterance to a feature set with various linguistic levels (i.e. n-grams of speech act and a concept sequence pairs, clue words, and state information of a domain frame). Then, the proposed model predicts the intention of the next utterance by using the feature set as inputs of CRFs (Conditional Random Fields). In the experiment in a schedule management domain, The proposed model showed the precision of 76.25% on prediction of user's speech act and the precision of 64.21% on prediction of user's concept sequence. The proposed model also showed the precision of 88.11% on prediction of system's speech act and the Precision of 87.19% on prediction of system's concept sequence. In addition, the proposed model showed 29.32% higher average precision than the previous model.

A spectrum based evaluation algorithm for micro scale weather analysis module with application to time series cluster analysis (스펙트럼분석 기반의 미기상해석모듈 평가알고리즘 제안 및 시계열 군집분석에의 응용)

  • Kim, Hea-Jung;Kwak, Hwa-Ryun;Kim, Yu-Na;Choi, Young-Jean
    • Journal of the Korean Data and Information Science Society
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    • v.26 no.1
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    • pp.41-53
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    • 2015
  • In meteorological field, many researchers have tried to develop micro scale weather analysis modules for providing real-time weather information service in the metropolitan area. This effort enables us to cope with various economic and social harms coming from serious change in the micro meteorology of a metropolitan area due to rapid urbanization such as quantitative expansions in its urban activity, growth of population, and building concentration. The accuracy of the micro scale weather analysis modules (MSWAM) directly related to usefulness and quality of the real-time weather information service in the metropolitan area. This paper design a evaluation system along with verification tools that sufficiently accommodate spatio-temporal characteristics of the outputs of the MSWAM. For this we proposes a test for the equality of mean vectors of the output series of the MSWAM and corresponding observed time series by using a spectral analysis technique. As a byproduct, a time series cluster analysis method, using a function of the test statistic as the distance measure, is developed. A real data application is given to demonstrate the utility of the method.

Development of Descending Thoracic Aortomyoplasty for Cardiac Bioassist (심장보조를 위한 흉부대동맥 근성형술 개발(예비 동물실험))

  • 오중환;박승일;김은기;김영호;류기홍;이상헌;원주호;서재정
    • Journal of Chest Surgery
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    • v.33 no.6
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    • pp.469-475
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    • 2000
  • Background: Thoracic aortomyoplasty is one of the surgical treatment for heart failure and has advantages over artificial heart or intraaortic balloon pumps. It uses autogenous skeletal muscles and solves problems such as energy source. However its use in clinical settings has been limited. This preliminary study was designed to develop surgical technique and to determine the effect of acute descending thoracic aortomyoplsty. Material and Method: Thirteen adult Mongrel dogs were used. The left latissimus dorsi muscle was wrapped around the descending aorta under general anesthesis. Swan-Ganz and microtipped Millar catheter were used for the hemodynamics and endocaridial viability ratio. Data were collected with myostimulator on and off in normal hearts and the ischemic hearts. Result: In normal hearts, the mean aortic diastolic pressure increased from 72$\pm$15mmHg at baseline to 78$\pm$13mmHg with stimulator on. Coronary perfusion pressure increased from 61$\pm$11mmHg to 65$\pm$9mmHg. Diastolic time increased from 0.288$\pm$0.003 msec to 0.290$\pm$0.003msec. Systolic time decreased from 0.164$\pm$0.002msec to 0.160$\pm$0.002 msec. Endocardial viability ratio increased from 1.21$\pm$0.22 to 1.40$\pm$0.18. In ischemic hearts, mean aortic diastolic pressure incrased from 56$\pm$21mmHg at baseline to 61$\pm$15mmHg with stimulator on. Coronary perfusion pressure increased from 48$\pm$17mmHg to 52$\pm$15mmHg. Diastolic time increased from 0.290$\pm$0.003 msec to 0.313$\pm$0.004msec. Systolic time decreased from 0.180$\pm$0.002 msec to 0.177$\pm$0.003 msec. Endovascular viability ratio increased from 0.9$\pm$0.31 to 1.1$\pm$0.31. The limited number of cases ruled out the statistic significance. Conclusion: Descending thoracic aortomyoplasty is a simple operation designed to use patient's own skeletal muscles. It trends to increase diastolic augmentation and coronary perfusion pressure. Modification of surgical technique and stimulator protocol would maximize the effect to assist the heart.

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A Study on the Application of the AMOEBA Technique for Delineating the Unique Primary Zones for the DIF Zoning Regulation (기반시설부담구역제도 제1단계 유일범역 도출과정에서의 AMOEBA 기법 적용에 관한 모의실험 연구)

  • Lee, Seok-Jun;Choei, Nae-Young
    • Journal of Cadastre & Land InformatiX
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    • v.47 no.2
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    • pp.5-18
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    • 2017
  • The AMOEBA approach in this study supplements the Hotspot method that had not been fully capable of dealing with the ecotone issues in designating the Development Impact Fee (DIF) zones as had been seen in the preceding study by Kim and Choei (2017). The AMOEBA procedure shares the common Getis-Ord statistic with the Hotspot technique but is more adequate to figure out the ecotones. For the comparative purpose, simulations are run by both methods for a series of different scenarios in terms of analytic spatial units (here, the square grids) from 100m up to 400m; and the zonal outcomes by both methods are compared using a set of evaluative indicators. In terms of the numerical scores, the performances by the two methods are much comparable except that the former is slightly superior with respect to the avoidance of the oversized spread of the selected zones whereas so is the latter with respect to the ease of infrastructure installation. It remains yet to be investigated by the extended studies that include in-depth field surveys to figure out the causes as well as the meanings of such differences in zonal determinations.

Application of Multispectral Remotely Sensed Imagery for the Characterization of Complex Coastal Wetland Ecosystems of southern India: A Special Emphasis on Comparing Soft and Hard Classification Methods

  • Shanmugam, Palanisamy;Ahn, Yu-Hwan;Sanjeevi , Shanmugam
    • Korean Journal of Remote Sensing
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    • v.21 no.3
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    • pp.189-211
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    • 2005
  • This paper makes an effort to compare the recently evolved soft classification method based on Linear Spectral Mixture Modeling (LSMM) with the traditional hard classification methods based on Iterative Self-Organizing Data Analysis (ISODATA) and Maximum Likelihood Classification (MLC) algorithms in order to achieve appropriate results for mapping, monitoring and preserving valuable coastal wetland ecosystems of southern India using Indian Remote Sensing Satellite (IRS) 1C/1D LISS-III and Landsat-5 Thematic Mapper image data. ISODATA and MLC methods were attempted on these satellite image data to produce maps of 5, 10, 15 and 20 wetland classes for each of three contrast coastal wetland sites, Pitchavaram, Vedaranniyam and Rameswaram. The accuracy of the derived classes was assessed with the simplest descriptive statistic technique called overall accuracy and a discrete multivariate technique called KAPPA accuracy. ISODATA classification resulted in maps with poor accuracy compared to MLC classification that produced maps with improved accuracy. However, there was a systematic decrease in overall accuracy and KAPPA accuracy, when more number of classes was derived from IRS-1C/1D and Landsat-5 TM imagery by ISODATA and MLC. There were two principal factors for the decreased classification accuracy, namely spectral overlapping/confusion and inadequate spatial resolution of the sensors. Compared to the former, the limited instantaneous field of view (IFOV) of these sensors caused occurrence of number of mixture pixels (mixels) in the image and its effect on the classification process was a major problem to deriving accurate wetland cover types, in spite of the increasing spatial resolution of new generation Earth Observation Sensors (EOS). In order to improve the classification accuracy, a soft classification method based on Linear Spectral Mixture Modeling (LSMM) was described to calculate the spectral mixture and classify IRS-1C/1D LISS-III and Landsat-5 TM Imagery. This method considered number of reflectance end-members that form the scene spectra, followed by the determination of their nature and finally the decomposition of the spectra into their endmembers. To evaluate the LSMM areal estimates, resulted fractional end-members were compared with normalized difference vegetation index (NDVI), ground truth data, as well as those estimates derived from the traditional hard classifier (MLC). The findings revealed that NDVI values and vegetation fractions were positively correlated ($r^2$= 0.96, 0.95 and 0.92 for Rameswaram, Vedaranniyam and Pitchavaram respectively) and NDVI and soil fraction values were negatively correlated ($r^2$ =0.53, 0.39 and 0.13), indicating the reliability of the sub-pixel classification. Comparing with ground truth data, the precision of LSMM for deriving moisture fraction was 92% and 96% for soil fraction. The LSMM in general would seem well suited to locating small wetland habitats which occurred as sub-pixel inclusions, and to representing continuous gradations between different habitat types.

Non Destructive Fast Determination of Fatty Acid Composition by Near Infrared Reflectance Spectroscopy in Sesame

  • Kang, Churl-Whan;Kim, Dong-Hwi;Lee, Sung-Woo;Kim, Ki-Jong;Cho, Kyu-Chae;Shim, Kang-Bo
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.51 no.spc1
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    • pp.283-291
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    • 2006
  • To investigate seed non destructive and fast determination technique utilizing near infrared reflectance spectroscopy (NIRs) for screening ultra high oleic (C18:1) and linoleic (C18:2) fatty acid content sesame varieties among genetic resources and lines of pedigree generations of cross and mutation breeding were carried out in National Institute of Crop Science (NICS). 150 among 378 landraces and introduced cultivars were released to analyse fatty acids by NIRs and gas chromatography (GC). Average content of each fatty acid was 9.64% in palmitic acid (C16:0), 4.73% in stearic acid (C18:0), 42.26% in oleic acid and 43.38% in linoleic acid by GC. The content range of each fatty acid was from 7.29 to 12.27% in palmitic, 6.49% from 2.39 to 8.88% in stearic, 12.59% of wider range compared to that of stearic and palmitic from 37.36 to 49.95% in oleic and of the widest from 30.60 to 47.40% in linoleic acid. Spectrums analyzed by NIRs were distributed from 400 to 2,500 nm wavelengths and varietal distribution of fatty acids were appeared as regular distribution. Varietal differences of oleic acid content good for food processing and human health by NIRs was 14.08% of which 1.49% wider range than that of GC from 38.31 to 52.39%. Varietal differences of linoleic acid content by NIRs was 16.41% of which 0.39% narrower range than that of GC from 30.60 to 47.01%. Varietal differences of oleic and linoleic acid content in NIRs analysis were appeared relatively similar inclination compared with those of GC. Partial least square regression (PLSR) among multiple variant regression (MVR) in NIRs calibration statistics was carried out in spectrum characteristics on the wavelength from 700 to 2,500 nm with oleic and linoleic acids. Correlation coefficient of root square (RSQ) in oleic acid content was 0.724 of which 72.4 percent of sample varieties among all distributed in the range of 0.570 percent of standard error when calibrated (SEC) which were considerably acceptable in statistic confidence significantly for analysis between NIRs and GC. Standard error of cross validation (SECV) of oleic acid was 0.725 of which distributed in the range of 0.725 percent standard error among the samples of mother population between analyzed value by NIRs analysis and analyzed value by GC. RSQ of linoleic acid content was 0.735 of which 73.5 percent of sample varieties among all distributed in the range of 0.643 percent of SEC. SECV of linoleic acid was 0.711 of which distributed in the range of 0.711 percent standard error among the samples of mother population between NIRs analysis and GC analysis. Consequently, adoption NIR analysis for fatty acids of oleic and linoleic instead that of GC was recognized statistically significant between NIRs and GC analysis through not only majority of samples distributed in the range of negligible SEC but also SECV. For enlarging and increasing statistic significance of NIRs analysis, wider range of fatty acids contented sesame germplasm should be kept on releasing additionally for increasing correlation coefficient of RSQ and reducing SEC and SECV in the future.

The Influence of Entrepreneurial Supporting Policy and Entrepreneurship on Entrepreneurial Intention in the fusion of industries -Considering the moderating effect of the business failure burden and self-efficacy- (융복합 산업 분야에서의 창업지원정책 및 기업가 정신이 창업의지에 미치는 영향 -사업실패 부담감과 자기효능감의 조절효과를 고려하여-)

  • Kwon, Myung-Kyu;Yang, Hae-Sool
    • Journal of Digital Convergence
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    • v.14 no.5
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    • pp.21-37
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    • 2016
  • The purpose of study was to examine the entrepreneurial supporting policy and the entrepreneurship which can affect the entrepreneurial intention, and to prove the moderating effect of the business failure burden and the self-efficacy on the relationship of the entrepreneurial supporting policy, entrepreneurship and the entrepreneurial intention through the empirical study in the fusion of industries. We used data from 321 survey participants by using structured questionnaires, excluding dishonest respondents, and statistical analysis was conducted using SPSS 18.0 statistic package. We used hierarchical regression technique to prove our hypothesis. The results showed that education and marketing support which are part of the entrepreneurial supporting policy in the fusion of industries will have positive influence on innovativeness, pro-activeness and risk acceptability which are part of entrepreneurship. It has been reported that only funding support has positive influence on entrepreneurship pro-activeness. The results also indicated that the entrepreneurial supporting policy will have positive influence on the entrepreneurial intention, but business failure burden and self-efficacy will have no moderating effect in the relation between the entrepreneurial supporting policy and the entrepreneurship. The theoretical and practical implications of the findings were discussed and the directions for future research were presented.

Effects of the Structured Nursing Intervention Program on Dysmenorrhea of Middle School Girls (구조화된 간호중재 프로그램이 여중생의 월경곤란증 완화에 미치는 영향)

  • Choi, Soung-Hee;Kim, Hyeon Ok
    • Journal of the Korean Society of School Health
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    • v.14 no.1
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    • pp.145-160
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    • 2001
  • The main purpose of this study is to identify the effects of a structured nursing intervention program on dysmenorrhea in middle school girls. This study employed two methods of research at the same time: a quasi-experiment pre- and post-test to use for comparison. Subjects were middle school girls assigned to the research program: 40 girls in the second grade, 40 girls in the third grade at K Girls' Middle School and H Girls' Middle School located in J city. The data were collected for 68 days from August 23 to October 30, 1999. The data were collected by observation technique and by a self-administered questionnaire. The instruments used for this study were as follows: the "Face Interval Pain Scale" menstrual pain instrument developed by McGreth(1987) and the "Menstrual Distress Questionnaire" dysmenorrhea instrument developed by Moos(1968). The dysmenorrhea knowledge instrument was developed by the researcher and refered to above. The research procedure was as follows: after preliminary examination, the experimental groups were provided educational programs with O.H.P. films developed by the researcher and with the videotape "first meeting" supported by P&G company and produced by EBS. The groups followed the educational programs twice for two weeks. At the beginning of menstruation, these subjects could choose one among the following choices: * Jacobson's progressively muscle relaxation method and massage treatment * Jacobson's progressively muscle relaxation method and hot bag treatment * Jacobson's progressively muscle relaxation method, a pain killer treatment, and massage treatment * Jacobson's progressively muscle relaxation method, a pain killer treatment, and hot bag treatment The dysmenorrhea of the control group were measured during the same period. The analysis of the collected data was done using an SPSS-PC+, descriptive statistic including real numbers, percentage, averages, standard deviations and t-test, $x^2$ test, and ANCOVA. The results of this study were as follows. (1) The knowledge level of the girls provided with the planned nursing intervention program was higher when compared to these who did not follow the educational programs. (2) The original difference in the dysmenorrhea level having been controled, the dysmenorrhea level made, nevertheless, a statistical difference between the experimental group and the control group(F=63.8, p=.00). Observed pain on quantity measurement of dysmenorrhea showed significant difference depending on the treatment(t=4.6, p=.00). In conclusion, those in the planned nursing intervention program had a higher knowledge level and fewer symptoms than the control group. Accordingly, the nursing intervention program for dysmenorrhea developed by the researcher can be effectively applied in nursing practice and can be the foundation for this kind of program.

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Comparative Analysis of T2 Sympaticotomy to T1 Sympathectomy in Treatment of Craniofacial Hyperhidrosis (안면부다한증에서의 T1 Sympathectomy와 T2 Sympathicotomy의 비교)

  • 윤용한;이두연;김해균;홍윤주
    • Journal of Chest Surgery
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    • v.31 no.11
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    • pp.1089-1093
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    • 1998
  • Background: In 1992, we first developed the technique for video-assisted thoracoscopic sympathectomy to treat palmar hyperhidrosis. It was soon proven to be a simple and effective therapy for essential hyperhidrosis. Clinically, patients suffereing from distressing hyperhidrosis in their heads and faces were observed. Materials and methods: From March 1997 to March 1998, the vidio-assisted thoracoscopic sympathectomy and sympathicotomy were performed in 60 patients suffering from craniofacial hyperhidrosis in the Department of Thoracic and Cardiovascular Surgery in the Respiratory Center of Yongdong Severance Hospital Seoul, Korea. Thirty-nine patients underwent a conventional sympathectomy(T1 sympathectomy group), and twenty-one patients underwent division of the sympathetic nerve trunk above the T2 sympathetic ganglion(T2 sympathicotomy). The median follow up was 9 months. Results: All of the treated patients obtained satisfactory alleviation of craniofacial hyperhidrosis. No recurrence was observed in group T1 sympathectomy whereas one occurred in sympathicotomy. The global rate of compensatory sweating was about the same in both groups ; 76.9% in T1 sympathectomy and 76.2% in T2 sympathicotomy. The rate of embarrassing and disabling compensatory sweating was 38.5% in T1 sympathectomy and 38.1% in T2 sympathicotomy with no significant in the statistic analysis(p> 0.05). No transient Horner's syndrome was observed in group T2 sympathicotomy whereas seven occurred in T1 sympathectomy with improvement in follow-up. Only an overnight hospital stay was required in both group. Conclusions: The video-assist thoracoscopic sympathicotomy is minimally invasive and effective. Video-assisted thoracoscopic T2 sympathicotomy has proven to be effective method and less complicated in treating patients with distressing craniofacial hyperhidrosis and consistent in obtaining the same results as T1 sympathectomy.

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