• KSCE Journal of Civil and Environmental Engineering Research
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• v.10 no.2
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• pp.103-112
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• 1990

This study examines the characteristics of soil behavior which includes many uncertainties in seismic design, evaluates the dynamic soil properties and studies the soil-structure interaction to generalize the applicability and economy of the available sites. An example analysis is performed for soil-structure system response assuming a containment structure built on site which includes soil layers using both elastic halfspace analysis and FEM analysis against the seismic loads from the actual design. This exercise is performed as a part of the safety analysis and economic assessment of the nuclear power plant built on soils. It includes the preparation of computer program capable of incorporating large nonlinearity in the analysis, resonable evaluation procedures to determine input soil data. Nonlinear FEM analysis of Seed and Idriss model is found suitable for the accurate analysis of dynamic response of soils. Linear FEM analysis using dynamic soil properties at strain level obtained by one-dimensional seismic response, and elastic half-space analysis using dynamic soil properties at strain level under static loads are recommended to evaluate the dynamic soil properties.

• Composites Research
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• v.29 no.6
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• pp.369-374
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• 2016

In this study, a structural optimal design of 10 MW composite blade was performed using bend-twist coupled(BTC) design concept. Bend-twist coupling of blade means the coupling behavior between the bending and torsional deflections due to the composite lamina with fiber angle biased from the blade longitudinal axis. This can potentially improve the overall performance of composite blade and reduce the dynamic loading. Parametric studies on layup angle, thickness and area of off-axis carbon UD were conducted to find the optimum coupling effect with weight reduction. Comparing the results of fatigue load analysis between conventional model and BTC applied model, the damage equivalent load(DEL) of blade root area were decreased about 3% in BTC model. To verify the BTC effect experimentally, a 1:29 scaled model was fabricated and the torsion at the tip under deflection behavior of blade stiffener model was measured by static load test.

• Molecules and Cells
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• v.38 no.3
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• pp.267-272
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• 2015

Nacre seashell is a natural osteoinductive biomaterial with strong effects on osteoprogenitors, osteoblasts, and osteoclasts during bone tissue formation and morphogenesis. Although nacre has shown, in one study, to induce bridging of new bone across large non-union bone defects in 8 individual human patients, there have been no succeeding human surgical studies to confirm this outstanding potency. But the molecular mechanisms associated with nacre osteoinduction and the influence on bone marrow-derived mesenchymal stem cells (BMSC's), skeletal stem cells or bone marrow stromal cells remain elusive. In this study we highlight the phenotypic and biochemical effects of Pinctada maxima nacre chips and the global nacre soluble protein matrix (SPM) on primary human bone marrow-derived stromal cells (hBMSCs) in vitro. In static co-culture with nacre chips, the hBMSCs secreted Alkaline phosphatase (ALP) at levels that exceeded bone morphogenetic protein (rhBMP-2) treatment. Concentrated preparation of SPM applied to Stro-1 selected hBMSC's led to rapid ALP secretions, at concentrations exceeding the untreated controls even in osteogenic conditions. Within 21 days the same population of Stro-1 selected hBMSCs proliferated and secreted collagens I-IV, indicating the premature onset of an osteoblast phenotype. The same SPM was found to promote unselected hBMSC differentiation with osteocalcin detected at 7 days, and proliferation increased at 7 days in a dose-dependent manner. In conclusion, nacre particles and nacre SPM induced the early stages of human bone cell differentiation, indicating that they may be promising soluble factors with osteoinductive capacity in primary human bone cell progenitors such as, hBMSC's.

• Journal of Internet Computing and Services
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• v.21 no.2
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• pp.109-119
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• 2020

The FPGAs are semiconductors that can be redesigned after initial fabrication. It is used in various embedded systems such as signal processing, automotive industry, defense and military systems. However, as the complexity of hardware design increases and the design and manufacturing process globalizes, there is a growing concern about hardware trojan inserted into hardware. Many detection methods have been proposed to mitigate this threat. However, existing methods are mostly targeted at IC chips, therefore it is difficult to apply to FPGAs that have different components from IC chips, and there are few detection studies targeting FPGA chips. In this paper, we propose a method to detect hardware trojan by learning the static features of hardware trojan in LUT-level netlist of FPGA using machine learning.

• Bulletin of the Korean Chemical Society
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• v.32 no.7
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• pp.2253-2259
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• 2011

The self-assembly of one novel organic complex based on chlorogenic acid (HCA) and 2,2'-bipyridine (2,2'-bipy) has been synthesized and characterized. The complex achieved by hydrogen-bonding interactions, adopted a 1:1 stoichiometry in a solid state. The proton transfer occurred from the carboxyl oxygen to the aromatic nitrogen atom to form salts CA${\cdot}$(2,2'-Hbipy), the 2,2'-Hbipy molecule individually occupies the pseudo-tetragonum that is formed with CA. In this paper, the interactions of CA${\cdot}$(2,2'-Hbipy) with bovine serum albumin (BSA) were studied by fluorescence spectrometry. For CA${\cdot}$(2,2'-Hbipy), HCA and 2,2'-bipy, the average quenching constants for BSA were $2.4384{\times}10^4$, $4.653{\times}10^3$, and $3.059{\times}10^3\;L{\cdot}mol^{-1}$, respectively. The mechanism for protein fluorescence quenching is apparently governed by a static quenching process. The Stern-Volmer quenching constants and corresponding thermodynamic parameters ${\Delta}$H, ${\Delta}$G and ${\Delta}$S were calculated. The binding constants and the number of binding sites were also investigated. The conformational changes of BSA were observed from synchronous fluorescence spectra.

• Journal of the Society of Naval Architects of Korea
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• v.52 no.6
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• pp.435-443
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• 2015

Offshore structure may be considerably vulnerable to fatigue failure while initial flaw propagates under cyclic loading, so crack propagation analysis/fracture/yield assessments about initial flaw detected by NDT are necessarily required. In this paper, case studies have been conducted by flaw assessment program using engineering criticality analysis (ECA) approach. Variables such as flaw geometry, flaw size, structure geometry, dynamic stress, static stress, toughness, crack growth rate, stress concentration factor (SCF) affected by weld are considered as analysis conditions. As a result, the safety of structure was examined during fatigue loading life. Also, critical initial flaw size was calculated by sensitivity module in the developed program. The flaw assessments analysis using ECA approach can be very useful in offshore industries owing to the increasing demand on the engineering criticality analysis of potential initial flaws.

• Physical Therapy Rehabilitation Science
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• v.5 no.3
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• pp.132-137
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• 2016

Objective: Eversion of the foot is created with internal rotation of the shank, and inversion of the foot is created with external rotation of the shank. The purpose of the study was to investigate the effect of continuous changes in the angle of the subtalar joint on lower extremity alignments. Design: Cross-sectional study. Methods: Seventeen healthy young adult subjects recruited. The subjects were asked to stand up in a natural standing position on a footplate with eye open and equal weight on each foot for 10s in two different conditions: The right subtalar joint was everted continuously $0^{\circ}-20^{\circ}$ and in separate segments of $0^{\circ}$, $5^{\circ}$, $10^{\circ}$, $15^{\circ}$, $20^{\circ}$. The averages of three trials were used. The observation of the changes in the lower extremity was performed with the use of 3-dimensional motion analysis. For data analysis, the SPSS 18.0 software using paired t-test and repeated measures analysis of variance (ANOVA) was applied. Results: The angle was significantly increased at the horizontal rotation angle of the shank, thigh, and ankle without anterior rotation of the pelvis (p<0.05). The maximum horizontal rotation angle at the thigh on $20^{\circ}$ was $-4.52^{\circ}$ in static, and $-3.10^{\circ}$ in the dynamic conditions compared to $0^{\circ}$. Conclusions: Increased unilateral foot pronation, thigh, shank, ankle horizontal rotation variance was significantly effective. The observation of the changes in foot abduction with the use of a 3-dimensional motion analysis augmented in predicting the angle values of each segment of the lower extremity. In further studies, a comparison of the right and left subtalar joints need to be investigated.

• Proceedings of the Korean Society of Crop Science Conference
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• 2017.06a
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• pp.328-328
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• 2017

Drought is a major limiting factor that reduces rice production and occurs often especially under recent climate change. Plants have the ability to alter their developmental morphology in response to changing environment, which is known as phenotypic plasticity. In our previous studies, we found that one chromosome segment substitution line (CSSL50 derived from Nipponbare and Kasalath crosses) showed no differences in shoot and root growth as compared with the recurrent genotype, Nipponbare under non-stress condition but showed greater growth responses compared with Nipponbare under mild drought stress condition. We hypothesized that reducing root respiration as metabolic cost, which may be largely a consequence of aerenchyma formation would be one of the key mechanisms for root plasticity expression. This study aimed to evaluate the root respiration and aerenchyma formation under various soil moisture conditions among genotypes with different root plasticity. CSSL50 together with Nipponbare and Kasalath were grown under waterlogged conditions (Control) and mild drought stress conditions (20% of soil moisture content) in a plastic pot ($11cm{\times}14cm$, ${\varphi}{\times}H$) and PVC tube ($3cm{\times}30cm$, ${\varphi}{\times}H$). Root respiration rate was measured with infrared gas analyzer (IRGA, GMP343, Vaisala, Finland) with a closed static chamber system. There was no significant difference between genotypes in control for shoot and root growth as well as root respiration rate. In contrast, all the genotypes increased their root respiration rates in response to mild drought stress. However, CSSL50 showed lower root respiration rate than Nipponbare, which was associated by higher root aerenchyma formation that was estimated based on internal gas space (porosity) under mild drought stress conditions. Furthermore, there were significant negative correlations between root length and root respiration rate. These results imply that reducing the metabolic cost (= root respiration rate) is a key mechanism for root plasticity expression, which CSSL50 showed under mild drought.

• The Journal of Korean Physical Therapy
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• v.13 no.1
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• pp.127-137
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• 2001

Low back pain is significant problem in today's society, with lifetime incidence rate reported between 50% and 90%. Many factors associated with LBP are reported. The purpose of this studies were to be evaluated static standing posture aberrations in chronic LBP in comparison with healthy individuals. The samples including 80 subjects recruited to the following two groups:patients and control(normal) Questionnaires were completed by 40 LBP patients and 40 controls at the department of Physical Therapy, Saejong neurosurgical clinic in Taegu city from October 1, 1999 to March 30, 2000. The angle of lumbar lordosis was measured on lateral x-ray films with standing position. In LBP groups. the mean degree of lumbar lordosis, sacral inclination, and lumbosacral joint angle were 29.9 ${\pm}$ 9.3, 34.8 ${\pm}$ 8.2, and 12.7 ${\pm}$ 5.7 respectively. Control groups, the mean degree of lumbar lordosis, sacral inclination and lumbosacral joint angle were 35.3 ${\pm}$ 7.8, 34.9 ${\pm}$ 6.4 and 12.5 ${\pm}$ 4.3 respectively. there were significantly decreaseds in lumbar lordosis in Low back pain group. lumbar lordosis on the working posture had significant differences among groups(sitting position patients 31.4 ${\pm}$ 9.3, standing position patients 29.4 ${\pm}$ 9.3, sitting position control 35.0 ${\pm}$ 6.4, standing position control 35.5 ${\pm}$ 8.8, respectively) (p=0.034). sacral inclination on the working posture had differences among groups(sitting position patients 35.9 ${\pm}$ 8.7.standing position patients 33.6 ${\pm}$ 7.6, sitting position control 33.9 ${\pm}$ 5.9. standing position control 35.6 ${\pm}$ 6.8, respectively). lumbersacral joint angle on the working Posture had differences among groups(sitting position patients 12.0 ${\pm}$ 5.6, standing position patients 13.4 ${\pm}$ 5.9, sitting position control 11.2 ${\pm}$ 3.0. standing position control 13.4$^{\circ}$, respectively).

• Journal of Korean Society of Steel Construction
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• v.14 no.2
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• pp.319-327
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• 2002

Development of high-strength and light-weight structural steel as well as advancement in steel structure analysis enable construction of long span steel arch bridge. In an economic viewpoint, however, the design values of long span steel arch bridge needs to be optimized to reduce construction cost and achieve proper levels of structural safety. This study investigated the girder depth and the rise-span ratio for optimum design values, as well as the spectral analysis for protection against earthquake. The relationship between rise-span ratio and girder depth was derived based on the parametric studies of the basic span lengths of 60, 70, 80, 90, and 100m using a commercial Cis SAP2000. The equation relating the two variables was derived using linear regression.