• Biomolecules & Therapeutics
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• v.19 no.4
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• pp.398-410
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• 2011

Over the past few decades, our understanding of the epidemiology and immunopathogenesis of Hodgkin lymphoma (HL) has made enormous advances. Consequently, the treatment of HL has changed significantly, rendering this disease of the most curable human cancers. To date, about 80% of patients achieve long-term disease-free survival. However, therapeutic challenges still remain, particularly regarding the salvage strategies for relapsed and refractory disease, which need further identification of better prognostic markers and novel therapeutic schemes. Although the precise molecular mechanism by which Epstein-Barr virus (EBV) contributes to the generation of malignant cells present in HL still remains unknown, current increasing data on the role of EBV in the pathobiology of HL have encouraged people to start developing novel and specific therapeutic strategies for EBV-associated HL. This review will provide an overview of therapeutic approaches for acute EBV infection and the classical form of HL (cHL), especially focusing on EBV-associated HL cases.

• Journal of Information Management
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• v.23 no.2
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• pp.57-72
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• 1992

Look for definition and characters of information and data, CDS/ISIS which is one of the total system in information processing are introduced. Explain the main function, characters and advantages of CDS/ISIS and forethermore try to encourage of the function of current ISIS. We need program for Korean language are available.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2009.10a
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• pp.333-336
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• 2009

the equipment increase switching frequency in order to achieve small size, a low noise, and light weight. however, the power switches have high power losses and switching stresses as the switching frequency is increased. In order to solve like this problem point from the present paper it proposed Intese Pulse Light of the half bridge methods which apply the start current circuit which applies the auxiliary equipment. Simulation and experimental result it leads and it brings is more qualitative there is 20% improvement and it confirmed that a possibility of measuring to the patient.

• International Journal of Advanced Culture Technology
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• v.10 no.3
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• pp.377-392
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• 2022

With the development of information and Internet technology, traditional museums have been long followed the trend of integrating innovative technological elements into the changed museums. It is necessary that the museums seize the opportunity of the trend transforming into smart museums, the key is to grasp the characteristics and laws of the Internet era, and use Internet thinking to explore the future development path. However, there are few studies on Internet thinking among the existing results. On the other hand, most of the relevant actual case studies still focus on the micro-level, which has obvious limitations. This paper will start from the current situation and trend, focus on the Palace Museum as a case study object, and discuss the problems and characteristics, so as to put forward the thinking about the development of smart museums in four aspects to explore the optimal path of transformation for smart museums.

• The Transactions of the Korean Institute of Power Electronics
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• v.27 no.1
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• pp.18-25
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• 2022

The cold staring issue of permanent magnet synchronous motors (PMSM) is a chronic problem in the field of PMSM sensorless drives. A traditional starting method, called the I-F method, is widely adopted because of its simple structure. However, when using this method, the pre-defined magnitude and frequency of the starting current should be changed according to the condition of the load and machine inertia. In this paper, a smart and simple algorithm for the cold starting of PMSM is proposed. In the proposed method, an integrated control angle from the estimated electrical rotor speed is used for vector control such as the indirect vector control of the induction machine. Thus, very stable cold starting is performed regardless of the machine load condition or inertia changing.

• The Bulletin of The Korean Astronomical Society
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• v.46 no.2
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• pp.41.2-41.2
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• 2021

I will start with presenting new results on the stellar populations of galaxies at a redshift of z=9-11, when the universe was only a few hundred million years old. By combining Hubble Space Telescope observations with Spitzer imaging data, I will show how challenging it is currently to measure basic physical properties of these objects such as star-formation rates, stellar masses and stellar ages. In particular, the current measurements greatly depend on the assumptions (priors) for the spectral energy distribution modeling. Finally, I will discuss how the James Webb Space Telescope (JWST) will revolutionize this field next year and allow us to probe and characterize the first generation of galaxies in much greater detail. Specifically, I will present an overview of the JWST Advanced Deep Extragalactic Survey (JADES), a joint program of the JWST/NIRCam and NIRSpec Guaranteed Time Observations (GTO) teams involving 950 hours of observation.

• Journal of Digital Convergence
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• v.15 no.11
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• pp.425-432
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• 2017

The current recommendation systems have problems including the difficulty of figuring out whether they recommend items that actual users have preference for or have simple interest in, the scarcity of data to recommend proper items due to the extremely small number of users, and the cold-start issue of the dropping system performance to recommend items that can satisfy users according to the influx of new users. In an effort to solve these problems, this study implemented a movie recommendation system to ensure user satisfaction by using the Fuzzy-Analytic Hierarchy Process, which can reflect uncertain situations and problems, and the data partition algorithm to group similar items among the given ones. The data of a survey on movie preference with 61 users was applied to the system, and the results show that it solved the data scarcity problem based on the Fuzzy-AHP and recommended items fit for a user with the data partition algorithm even with the influx of new users. It is thought that research on the density-based clustering will be needed to filter out future noise data or outlier data.

• Journal of the Korean association of regional geographers
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• v.21 no.4
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• pp.631-638
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• 2015

The aim of this article is to analyze problems of the government-led region-based business-university-research institute collaborations(BURIC) in Korea and to present main issues for solving and improving the current 'cul-de-sac' of these collaborations. The main problem of such collaborations is the wider divergence of opinions by actors who implement projects of the BURIC funded by the central and local government. Due to this problem, each region, mainly the non-Seoul metropolitan region, in Korea has problems of the system and people for BURIC. Within this context, main issues of the government-led and region-based BURIC is focused upon BURIC for the start-up of self-employment and the expansion of companies' lifespan. Since 2000, experts and policy-makers have emphasized business- (or company-) centered BURIC rather than University-focused one. This point of view should be improved or corrected. That is to say, policies of BURIC are in need of focusing upon the start-up for self-employment and the expansion of companies' lifespan.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2014.10a
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• pp.565-568
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• 2014

This paper presents a 0.2V DC/DC boost converter with regulated output for thermoelectric energy harvesting. To use low voltages from a thermoelectric device, a start-up circuit consisting of native NMOS transistors and resistors boosts an internal VDD, and the boosted VDD is used to operate the internal control block. When the VDD reaches a predefined value, a detector circuit makes the start-up block turn off to minimize current consumption. The final boosted VSTO is achieved by alternately operating the sub-boost converter for VDD and the main boost converter for VSTO according to the comparator outputs. When the VSTO reaches 2.4V, a buck converter starts to operate to generate a stabilized output VOUT. Simulation results shows that the designed converter generates a regulated 1.8V output from an input voltage of 0.2V, and its maximum power efficiency is 60%. The chip designed using a $0.35{\mu}m$ CMOS process occupies $1.1mm{\times}1.0mm$ including pads.

• Journal of the Korean BIBLIA Society for library and Information Science
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• v.32 no.1
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• pp.361-390
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• 2021

The purpose of this study is to provide basic data for bookstart programs to public libraries and related institutions by investigating and analyzing bookstart preferred programs, user satisfaction and reuse intentions based on the current status of bookstart services and programs for multicultural families nationwide. It is to propose an improvement plan for the multicultural family bookstart program. To this end, user satisfaction and reuse intention were surveyed and hypotheses were verified through a survey of bookstart program participants. For statistical analysis, SPSS 25 was used. As a result of this study, First, there was a significant difference in the bookstart program for multicultural families according to their children's age and average monthly education expenses. Second, in the satisfaction of the multicultural family bookstart program, only the use and service support, and the quality of facilities and environment were found to have a significant positive (+) effect. Third, it was found that the re-use intention of the multicultural family bookstart program had a significant positive (+) effect only on the quality of use and service support. Fourth, it was verified that satisfaction with the book start program for multicultural families had a significant positive (+) effect on the intention to reuse. In addition, it suggested the improvement plan for the multicultural family book start program.