• 한방안이비인후피부과학회지
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• 제26권2호
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• pp.10-18
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• 2013

Objectives : We performed a pilot study to investigate inter- and intra-rater reliability of pattern identification using nasal endoscopy for allergic rhinitis(AR). Methods : Eight experts of ophthalmology, otolaryngology and dermatology of Korean medicine evaluated 20 nasal endoscopy photograph cases of AR patients with pattern identification index using nasal endoscopy for AR including the nasal membrane color(pale / hyperemia), nasal membrane humidity(dryness / dampness), rhinorrhea(watery / yellow), and membrane edema (atrophic / edematous) on nasal endoscopy. Results : Intra-rater agreement(%) and Kappa coefficient was generally from 'moderate' to 'good'(% agreement: 73.13-90% / Kappa coefficient: 0.547-0.748). Inter-rater agreement(%) and Kappa coefficient was also from 'moderate' to 'good' (% agreement: 65-85% / Kappa: 0.475-0.778) except 'humidity(dryness / dampness)' item (% agreement: 55.98% / Kappa: 0.340). In findings of subgroup analysis according to affiliation of raters, Inter-rater agreement(%) and Kappa coefficient of raters in same affiliation was higher than inter-rater agreement(%) and Kappa coefficient of raters in different affiliation except 'dryness / dampness' item. Conclusions : It is necessary to improve objectivity and reproducibility of pattern identification using nasal endoscopy for allergic rhinitis(AR) through the development of detail-oriented criteria and enhanced training of clinicians with development of standard operating procedures(SOPs).

• Journal of Genetic Medicine
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• 제14권1호
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• pp.8-17
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• 2017

Purpose: Pulse wave velocity (PWV) is an indicator of arterial stiffness, and is considered a marker of vascular damage. However, a genome-wide association study analyzing single nucleotide polymorphisms (SNPs) associated with brachial-ankle PWV (baPWV) has not been conducted in healthy populations. We performed this study to identify SNPs associated with baPWV in healthy populations in Korea. Materials and Methods: Genomic SNPs data for 2,407 individuals from three sites were analyzed as part of the Korean Genomic Epidemiologic Study. Without replication samples, we performed multivariable analysis as a post hoc analysis to verify the findings in site adjusted analysis. Healthy subjects aged between 40 and 70 years without self-reported history or diagnosis of hypertension, diabetes, hyperlipidemia, heart disease, cerebrovascular disease and cancer were included. We excluded subjects with a creatinine level >1.4 mg/dL (men) and 1.2 mg/dL (women). Results: In the site-adjusted association analysis, significant associations (P<$5{\times}10^{-8}$) with baPWV were detected for only 5 SNPs with low minor allele frequency. In multivariable analysis adjusted by age, sex, height, body mass index, mean arterial pressure, site, smoking, alcohol, and exercise, 11 SNPs were found to be associated (P<$5{\times}10^{-8}$) with baPWV. The 5 SNPs (P<$5{\times}10^{-8}$) linked to three genes (OPCML, PRR35 and RAB40C) were common between site-adjusted analysis and multivariable analysis. However, meta-analysis of the result from three sites for the 11 SNPs showed no significant associations. Conclusion: Using the recent standard for genome-wide association study, we did not find any evidence of significant association signals with baPWV.

• 한국유기농업학회지
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• 제26권1호
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• pp.57-72
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• 2018

Organic agriculture seeks sustainable agriculture. Organic agriculture is based on circulating agriculture of a family farm unit. However, as of the end of 2016, only 33 out of the total organic farming farms were implementing Crop-Livestock cycling organic farming. The reason seems to be a matter of income after all. The optimal size combination refers to the scale by which family farms can maintain their quality of life while engaging in farming activities. In other words. it is a farm scale that maintains optimal income through stable labor costs. In the meantime, there has been no previous study on the optimal economical combination of Crop-Livestock cycling farming. Choi (2016) analyzed whether the economies of scope (EOS) were realized in the combined production by using the management data of the farmers who practiced Crop-Livestock cycling organic farming for four years. As a result, it has been revealed that the EOS measurement value is 0 or more so the economies of scope are being realized. Therefore, the purpose of this empirical analysis is to identify farm incomes under this circumstance. It is assumed that the optimum production is achieved by balancing the total income curve and the total cost curve in the optimal scale production range. The results of the analysis are as follows. First, the income after the conversion to Crop-Livestock cycling farming was 44,789,280 won, the sum of the seedling-livestock sector, which was 17,873,120 won higher when the non-Crop-Livestock cycling farming was assumed. The same is true for 2014 and 2015. The reason for this is that pig droppings were composted from organic seedlings, and the cost of selling pork was 150,000 won/per pig more expensive even though the manufacturing cost of organic feeds was higher than the purchasing cost. Secondly, this study simulated the result that the economic index varies when the farm size combination is changed by the farm size of 100% standard (S100) as of 2014. S130 is the increase in size from 100% of 2014, whereas S30 is the result of 3ha crop and 66 livestock (pigs). As a result of this simulation, Crop-Livestock cycling farming income decreased more than non-Crop-Livestock cycling farming as the farm size decreased, whereas the income decreased as the farm size increased. When the size was reduced below S50, the income tended to decrease. In this situation, EOS changed in the same direction. The results showed that when the farming size was reorganized and reduced to 50% compared to 2014, the income and income difference was the highest. At the same time, economies of scope (EOS) were the highest at 0.12985. In other words, it was found that the income of farm houses in a family farm unit sector was the best in the combination of 1.5ha crop agriculture and 110 livestock (pigs).

• 한국산학기술학회논문지
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• 제10권9호
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• pp.2451-2459
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• 2009

통증이 거의 없는 새로운 모세혈액 채혈기법인 진공자동채혈법(vacuum assisted auto-lancing)의 정확도를 분석하고자 전형적인 대체부위인 전완(팔) 부위에서 채혈하여 측정한 혈당값을 표준 채혈부위인 정맥 및 손가락에서 채혈하여 측정한 혈당값과 비교, 분석하는 연구를 수행하였다. C대학교병원을 내원한 531명의 환자들을 대상으로 왼손 집게손가락 끝과 왼쪽 전완 부위에서 말초혈액의 혈당을 측정하였고, 곧바로 정맥 채혈하여 혈당을 측정하였다. 전완 부위 혈당 평균값이 손가락보다 정맥 혈당값에 더욱 가까웠으나 이들 간의 차이는 약 10 mg/dL 범위에 불과하여 임상적으로는 동일한 값들로 볼 수 있었다. 측정값들 간에 상관분석을 수행한 결과 손가락과 정맥 채혈의 혈당값 간의 상관계수는 0.94, 전완 부위와 정맥 혈당값 간의 상관계수는 0.92, 또한 전완 부위와 손가락 채혈 간의 상관계수는 0.94로 모두 매우 유의한 상관관계를 보였다(p<0.001). 따라서 대체부위인 전완 부위 혈당검사의 정확도가 실험적으로 입증되었다. 손가락 혈당검사는 상당한 채혈 통증이 수반되어 당뇨 환자들이 자가 검사를 기피하는 주요 원인이 되지만, 전완 부위에서 진공자동채혈하면 통증이 거의 없으므로 만성 당뇨환자들의 자가 질환관리를 위해 매우 유용하리라 기대된다.

• Journal of Korean Neurosurgical Society
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• 제60권5호
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• pp.604-609
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• 2017

Objective : An adjustable Ghajar guide is presented to improve the accuracy of the original Ghajar guide technique. The accuracy of the adjustable Ghajar guide technique is also investigated. Methods : The coronal adjustment angle from the orthogonal catheter trajectory at Kocher's point is determined based on coronal head images using an electronic picture archiving and communication system. For the adjustable Ghajar guide, a protractor is mounted on a C-shaped basal plate that is placed in contact with the margin of a burrhole, keeping the central $0^{\circ}$ line of the protractor orthogonal to the calvarial surface. A catheter guide, which is moved along the protractor and fixed at the pre-determined adjustment angle, is then used to guide the ventricular catheter into the frontal horn adjacent to the foramen of Monro. The adjustable Ghajar guide technique was applied to 20 patients, while a freehand technique based on the surface anatomy of the head was applied to another 47 patients. The accuracy of the ventricular catheter placement was then evaluated using postoperative computed tomography scans. Results : For the adjustable Ghajar guide technique (AGT) patients, the bicaudate index ranged from 0.23 to 0.33 ($mean{\pm}standard$ deviation [SD] : $0.27{\pm}0.03$) and the adjustment angle ranged from $0^{\circ}$ to $10^{\circ}$ ($mean{\pm}SD:5.2^{\circ}{\pm}3.2^{\circ}$). All the AGT patients experienced successful cerebrospinal fluid diversion with only one pass of the catheter. Optimal placement of the ventricular catheter in the ipsilateral frontal horn approximating the foramen of Monro (grade 1) was achieved in 19 patients (95.0%), while a suboptimal trajectory into a lateral corner of the frontal horn passing along a lateral wall of the frontal horn (grade 3) occurred in 1 patient (5.0%). Thus, the AGT patients experienced a significantly higher incidence of optimal catheter placement than the freehand catheterized patients (95.0% vs. 68.3%, p=0.024). Moreover, none of the AGT patients experienced any tract hemorrhages along the catheter or procedure-related complications. Conclusion : The proposed adjustable Ghajar guide technique, using angular adjustment in the coronal plane from the orthogonal trajectory at Kocher's point, facilitates accurate freehand placement of a ventricular catheter for hydrocephalic patients.

• 한국산림과학회지
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• 제90권1호
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• pp.146-154
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• 2001

북한산국립공원(北漢山國立公園) 북동사면(北東斜面) 일대(一帶) 계류수(溪流水)의 이화학적(理化學的) 수질특성(水質特性)을 계절별로 파악함으로써 국립공원내(國立公園內) 계류수질(溪流水質) 보전(保全)을 위한 과학적 기초 자료를 제공하기 위하여 1998년 7월부터 2000년 11월까지 매월 4개 지점의 계류수질을 분석한 결과, 이 지역 계류수의 평균pH는 6.6(6.53~6.74), 평균용존산소량은 11.2(11.0~11.3)$mg/{\ell}$로 하천수질환경기준 상수원수 1급수의 범위 내였다. 이 지역 계류수(溪流水)의 평균전기전도도(平均電氣傳導度)는 106.8(52.3~154.0)${\mu}S/cm$이었으나, 음식점, 사찰 등에 영향받는 하류지역에서는 139.4~154${\mu}S/cm$로 상류지역 (52.3~81.6${\mu}S/cm$)보다 약 1.7~3.0배 높았다. 또한, 북한산국립공원(北漢山國立公園) 북동사면 일대 계류수에서 전기전도도(電氣傳導度)와 용존음이온량($Cl^-$, $NO{_3}^-$, $SO{_4}^{2-}$)은 상류(上流)보다는 하류(下流)에서 높게 나타났으며, 계절별로는 봄이나 여름보다는 가을에 계류수질오염(溪流水質汚染)이 더 심한 것으로 분석(分析)되었다.

• 한국기후변화학회지
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• 제6권4호
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• pp.357-366
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• 2015

This study was conducted to estimate carbon stocks of Quercus serrata with drawing volume of trees in each tree height and DBH applying the suitable stem taper equation and tree specific carbon emission factors, using collected growth data from all over the country. Information on distribution area, tree number per hectare, tree volume and volume stocks were obtained from the $5^{th}$ National Forest Inventory (2006~2010), and method provided in IPCC GPG was applied to estimate carbon storage and removals. Performance in predicting stem diameter at a specific point along a stem in Quercus serrata by applying Kozak's model,$d=a_1DBH^{a_2}a_3^{DBH}X^{b_1Z^2+b_2ln(Z+0.001)+b_3{\sqrt{Z}}+b_4e^Z+b_5({\frac{DBH}{H}})}$, which is well known equation in stem taper estimation, was evaluated with validations statistics, Fitness Index, Bias and Standard Error of Bias. Consequently, Kozak's model turned out to be suitable in all validations statistics. Stem volume tables of Quercus serrata were derived by applying Kozak's model and carbon stock tables in each tree height and DBH were developed with country-specific carbon emission factors ($WD=0.65t/m^3$, BEF=1.55, R=0.43) of Quercus serrata. As a result of carbon stock analysis by age class in Quercus serrata, carbon stocks of IV age class (11,358 ha, 36.5%) and V age class (10,432; 33.5%) which take up the largest area in distribution of age class were 957,000 tC and 1,312,000 tC. Total carbon stocks of Quercus serrata were 3,191,000 tC which is 3% compared with total percentage of broad-leaved forest and carbon sequestration per hectare(ha) was 3.8 tC/ha/yr, $13.9tCO_2/ha/yr$, respectively.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• 제22권6호
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• pp.511-517
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• 2019

Purpose: On the basis of evidence, we aimed to reevaluate the necessity of the empirical proton pump inhibitor (PPI) trial for children with suspected gastroesophageal reflux disease (GERD). Methods: We analyzed the frequency of GERD in 85 school-age children with gastroesophageal reflux (GER) symptoms, who received 24-hour esophageal pH monitoring and/or upper endoscopy. According to the reflux index (RI), the children were classified into normal (RI <5%), intermediate (5%${\leq}$ RI <10%), or abnormal (RI ${\geq}$10%) groups. Results: Fifty six were female and 29 were male. Their mean age was $12.6{\pm}0.5$ (${\pm}$standard deviation) years (range: 6.8-18.6). The RI analysis showed that the normal group included 76 patients (89.4%), the intermediate group included 6 patients (7.1%), and the abnormal group included 3 patients (3.5%). The DeMeester score was $5.93{\pm}4.65$, $14.68{\pm}7.86$ and $40.37{\pm}12.96$ for the normal, intermediate and abnormal group, respectively (p=0.001). The longest reflux time was $5.56{\pm}6.00$ minutes, $9.53{\pm}7.84$ minutes, and $19.46{\pm}8.35$ minutes in the normal, intermediate, and abnormal group, respectively (p=0.031). Endoscopic findings showed reflux esophagitis in 7 patients. On the basis of the Los Angeles Classification of Esophagitis, 5 of these patients were included in group A, 1 patient, in group B and 1 patient, in group C. Conclusion: The incidence of GERD was very low in school-age children with GER symptoms. Therefore, injudicious diagnostic PPI trials would be postponed until the actual prevalence of GERD is verified in future prospective studies.

• 한국항만경제학회지
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• 제30권1호
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• pp.159-173
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• 2014

본 연구는 항만물류기업의 직업기초능력 평가 요인의 우선순위를 분석하기 위해 고용노동부에서 제공하는 국가직무표준의 직업기초능력 지표를 활용하여 연구모형을 설계하였다. 총 10개의 1계층 요인과 34개의 제 2계층 요인에 해당하는 요소를 AHP 분석기법을 활용하여 우선순위 분석을 실시하였다. 항만물류기업의 직업기초능력에 따른 AHP 분석결과 우선순위로 문서개발능력, 대인관계능력, 의사소통능력, 조직이해능력, 직업윤리, 정보능력, 자원관리능력, 자기개발능력, 기술능력, 수리능력의 순위로 나타났다. 특히 2계층 요인의 최종 순위에서 대인관계 능력의 갈등관리능력(2 순위), 리더십능력(3 순위), 팀 능력(7 순위), 고객서비스능력(9 순위), 협상능력(10 순위) 등의 5개의 능력이 상위 10 순위 안에 들었다. 이러한 결과를 분석하면 다음과 같다. 첫째, 항만물류기업의 특성 상 각 화주와 운송사 등의 고객사와 지속적인 커뮤니케이션이 필요함으로써 갈등관리능력, 리더십능력, 팀워크능력, 고객서비스능력 및 협상능력 등의 대인관계능력을 우선시 여기고 있음을 알 수 있다. 둘째, 항만물류 관련 문제 발생 시 실시간으로 문제를 인식하고 대안을 선택하여 적용하고 평가할 수 있는 문제처리능력이 중요함을 알 수 있었다. 셋째, 의사소통능력에서 조직내부의 문서처리를 위한 기본적으로 문서이해능력이 중요시 여기고 있음을 상대적 평가 분석을 통해 확인할 수 있었다. 넷째, 항만물류기업의 업무의 우선순위 파악하여 업무활동을 계획하고 결과 평가하는 조직이해능력의 업무이해능력 역시 항만물류기업에서는 직무 수행에 필요한 요인으로 판단을 할 수 있었다. 본 연구는 항만물류기업에 직무를 수행하는데 있어서 교육과정을 선정하고 설계하는데 있어 중요한 요소로 활용할 수 있으며, 현장 중심의 직무교육과정 개발의 문제점을 최소화하는 직업기초능력의 프레임워크를 제시하는데 연구의 의의가 있다.

• 사상체질의학회지
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• 제25권3호
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• pp.145-157
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• 2013

Objectives This study was aimed to reveal the characteristics of the body shape, face, voice and temperament in Taeyangin. Methods The subjects were recruited from November 2005 to August 2012. Sasang constitutional specialist in each clinics confirmed the Sasang Constitution. Taeyangin (TY) became a standard guidance to be compared with each other Sasang type. Anova test was used in analyzing continuous variables and factor analysis was conducted in temperament questionnaire in advance. Generalized propensity score with age and body mass index (BMI) was used in adjusted model. Significant level was .05 Results 1. The TY body shape were generally smaller than Taeeumin (TE) (p<0.001) and Soyangin (SY) (p<0.05) in crude. The TY body shape were still smaller than TE (p<0.05) and there was no significant difference between TY and SY except rib circumference in males and forehead circumference (p<0.05) in females in adjusted model. 2. The size of face and nose in TY was smaller than in TE and there was different between males and females' TY and others in the characteristics of eye, nose and forehead variables in crude (p<0.05). Most of differences between TY and TE were disappeared in adjusted model. 3. The vocal height and speed of TY was different other types and there was different between males and females' TY in some of frequency change rate in crude (p<0.05). Most of differences between TY and other types were similar before and after adjusted model. 4. The temperament of TY was different with SE before and after adjusted mode 1 (p<0.05). TY males showed difference in expression factor and TY females showed difference in behavior factor compared with TE respectively (p<0.05). Conclusions This study reveals characteristics of body shape, face, voice and character in the TY males females compared with each other type respectively.