• 제목/요약/키워드: stability period

검색결과 1,554건 처리시간 0.024초

Comparative study of linear and cyclic forms of apoptosis-targeting peptide

  • Ha, Yeong Su;Soni, Nisarg;Huynh, Phuong Tu;Lee, Byung-Heon;An, Gwang Il;Yoo, Jeongsoo
    • 대한방사성의약품학회지
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    • 제2권2호
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    • pp.96-102
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    • 2016
  • Apoptosis, a genetically determined process of programmed cell death, is considered a vital component of various processes including normal cell turnover, animal development, and tissue homeostasis. It has a crucial role in many medical disorders and hence the development of non-invasive imaging tool is highly demanded. Recently, we have developed a peptide-based radioactive probe (ApoPep-1) for apoptosis detection. In that work the potential of probe for apoptosis detection was verified, however in vivo stability of radiolabeled peptide was not enough to monitor apoptosis for extended period. In current study, we prepared cyclic ApoPep-1 peptides to improve the stability of origianl linear ApoPep-1 and carried out direct comparison studies in vitro and in vivo. A targeting efficacy of newly synthesized cyclic ApoPep-1 peptide for apoptosis was confirmed in acute myocardial infarct model.

Effect of Swiss Chard (Beta vulgaris var. cicla) as Nitrite Replacement on Color Stability and Shelf-Life of Cooked Pork Patties during Refrigerated Storage

  • Shin, Dong-Min;Hwang, Ko-Eun;Lee, Cheol-Won;Kim, Tae-Kyung;Park, Yoo-Sun;Han, Sung Gu
    • 한국축산식품학회지
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    • 제37권3호
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    • pp.418-428
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    • 2017
  • In this study, the effects of pre-converted nitrite from Swiss chard powder (PS) on the color stability and shelf-life of cooked pork patties during refrigerated storage for 28 d were investigated. Nitrite was added at a concentration of approximately 120 ppm. Five treatments were formulated as follows: Control (120 ppm nitrite), T1 (2% PS), T2 (2% pre-converted nitrite from celery powder; PC), T3 (1% PS + 60 ppm nitrite), and NC (nitrite-free). The T1 and T3 samples had higher nitrosoheme pigment contents, which were associated with the redness of the samples (p<0.05). T1 resulted in the highest redness value (p<0.05). The redness and yellowness of the cooked pork patties increased with increasing PS levels. The pH of the samples subjected to all treatments decreased with progress of the storage period (p<0.05). The pH of the T1 and T3 samples treated with PS was lower (p<0.05) than that obtained with other treatments, as PS has a lower pH value. The treatments in which PS was added were most effective for reducing the level of thiobarbituric acid reactive substances (TBARS) and the residual nitrite content relative to the control. T1 resulted in the highest flavor, off-flavor, and overall acceptability scores during storage (p<0.05). The total viable bacterial count for all treatments was below 1 Log CFU/g, and E. coli and coliform bacteria were not detected during storage. Therefore, these results suggested that pre-converted nitrite from Swiss chard powder is a potential replacement for nitrite in meat products.

자연 해성점토 위에 건설한 폐기물매립장 기호지반의 침하와 활동 가능성 (Settlement and Sliding Possibility of the Foundation of the Waste Landfill Constructed on Natural Marine Clay)

  • 김수삼;강기민
    • 한국지반공학회지:지반
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    • 제12권5호
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    • pp.41-54
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    • 1996
  • 본 논문은 폐기물의 하중과 침출수위의 변화를 고려할 수 있는 컴퓨터 프로그램 CONSOL을 이용하여 폐기물 매립이 진행되는 동안과 이후의 해안 폐기물 매립장의 압밀침하량을 분석하였다. 또한, 이들 변화된 기초점토지반 강도특성하에서 매립지 기초지반을 포함한 제체사면의 안정성 해석을 수행하였으며, 현장 침하계측자료와 본 논문의 이론적 침하량을 비교 검토하였다. 그 결과, 단계별 폐기물 매립이 실시됨에도 침출수위가 함께 상승할 경우 점토지반의 강도를 향상시키는 유효응력 증가가 거의 없어 매립높이가 증가할수록 안정성이 확보되기 어려운 것으로 나타났으며, 그 결과 매립경사구배를 낮추거나 배수공법에 의한 침출수위를 절감시키는 등의 보완 작업이 필요한 것으로 나타났다. 압밀해석으로부터 구한 침하량은 실측침하량 자료와 비교적 잘 일치하였다.

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Impacts of Dietary Vitamins and Trace Minerals on Growth and Pork Quality in Finishing Pigs

  • Choi, S.C.;Chae, B.J.;Han, In K.
    • Asian-Australasian Journal of Animal Sciences
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    • 제14권10호
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    • pp.1444-1449
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    • 2001
  • Two feeding trials were conducted to determine the effect of inclusion levels or deletion of vitamin-trace mineral (VM) premixes on growth performance and pork quality in finishing pigs. In exp. 1, a total of ninety-six crossbred pigs $(Landrace\;{\times}\;Yorkshire\;{\times}\;Duroc,\;85.09{\pm}3.12kg)$ were used for a 4-week feeding triaL Treatments were premix supplementation at the level of 50% (Control), 100%, 150%, and 200% of NRC (1998) requirements for vitamins and trace minerals. In exp. 2, a total of one hundred and eight crossbred pigs $(Landrace\;{\times}\;Yorkshire\;{\times}\;Duroc,\;84.76{\pm}0.58kg)$ were used for a 4-week feeding trial. Treatments were premix supplementation at the level of 0% (Control), 200% VM, and 200% vitamin E and Se listed in NRC (1998) requirements. Average daily gain (ADG) and feed/gain (F/G) were the highest at 150% VM addition level (quadratic, p<0.05) among treatments. Dressing percentage and backfat thickness in pigs were not affected by different addition levels of VM premixes. Pork stability in terms of TBARS was linearly (p<0.05) improved as dietary VM premix was increased (exp. 1). ADG, F/G and pork stability (TBARS) were also reduced (p<0.05) when VM premixes were deleted. However, supplementation of vitamin E and Se improved (p<0.05) ADG and pork stability when pigs were fed diets without VM premixes (exp. 2). In conclusion, deleting dietary VM premixes gave negative effects on growth performance and pork quality for the last 4 weeks of finishing period.

자본유출입 급변동과 외환 및 유통시장 안정성에 관한 연구 (A Study on the Sudden Stop in Capital Flows and Foreign Exchange and Distribution Market Stability)

  • 김윤철;이명훈
    • 유통과학연구
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    • 제14권12호
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    • pp.79-87
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    • 2016
  • Purpose - Since 1990, the sudden stop in capital flows has caused the economic crisis. The purpose of this research is to suggest the policy measures to mitigate the risk of the sudden stop in capital flows. To this end, we examine the theoretical framework and analyze the case study for countries which are faced with the sudden stop. Also we examine the structural problems of the foreign exchange market in Korea and derive the policy implications to prevent the sudden stop. Research design, data, and methodology - The criteria of whether the sudden stop in capital flows occurs are based upon Calvo et al. (2008). In case the proxy variable for the balance of capital account decreases from the average by over twice standard deviation, we determine that the sudden stop occurs for that country. The sample period is from January 1990 to December 2008, as in Calvo (2014). The sample countries are 17 developed countries and 19 emerging market countries, which are different from those of the previous papers as Agosin and Huaita (2012), and Calvo (2014). When the exchange market pressure index(EMPI) is deviated from the average by over three times standard deviation, we determine that the foreign exchange market is unstable for that country. Results - We find that the characteristics of the sudden stop in capital flows are the bunching or contagion among countries, the rapid drop in real effective exchange rate, and the huge decrease in foreign exchange reserves. Many countries tried to increase foreign exchange reserves and regulate capital flows. Also the foreign exchange market in Korea are found to be the volatile exchange rate, the vulnerable external debt and careless management of the foreign exchange derivatives transaction risk. Conclusions - To lessen the risk in the sudden stop of capital flows, this research suggests the some useful policy measures. To enhance the foreign exchange and distribution market stability, we should improve the price mechanism of exchange rate, hold the appropriate level of foreign exchange reserves, prevent excessive inflows of foreign exchange and promote sound transactions of foreign exchange derivatives.

세탁 및 건조과정에 의한 스판덱스 혼방 직물의 변형 비교 (The Effects of Washing and Drying on the Dimensional Stability of Woven Fabrics with and without Spandex)

  • 윤창상;고예린;송경희;신효담;박정희
    • 한국의류학회지
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    • 제41권3호
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    • pp.458-467
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    • 2017
  • There is increased interest in clothes dryers and garments made of spandex-blend woven fabrics; however, there is limited information available for the laundering and drying these clothes. This study investigates the effects of washing and drying on shrinkage, skewness, and wrinkle for woven fabrics with and without spandex. When spandex with good elastic recovery was blended, the deformed shape from washing and drying improved skewness and wrinkle by easily returning to its original shape. However, these properties had a negative effect on shrinkage in terms of length and area change. When the influence of clothes maintenance was classified, the drying process had the biggest influence of 58%, followed by spinning-rinsingwashing. Tumble drying, in which the fabric is exposed to mechanical force and heat for a long period, had more negative effects on the dimensional stability than line drying. The spandex blend had the effect of preventing skewness and wrinkle in garments, but it was also shown to accelerate shrinkage by garment maintenance cycles. It was important to control drying in order to reduce shrinkage during the maintenance process; consequently, this had the greatest influence on the dimensional stability of fabrics. Therefore, line drying was more advantageous for spandex-blend fabrics than tumble drying in terms of management for shrinkage, skewness, and wrinkle.

An Anthropometric and Three-Dimensional Computed Tomographic Evaluation of Two-Point Fixation of Zygomatic Complex Fractures

  • Jo, Taehee;Kim, Junhyung
    • Archives of Plastic Surgery
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    • 제41권5호
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    • pp.493-499
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    • 2014
  • Background Maintaining stability and restoring the aesthetic appearance are the fundamental goals when managing zygomatic fractures. We aimed to evaluate the stability and anthropometric outcomes of zygomatic fracture patients who underwent two-point fixation involving the infraorbital rim and zygomaticomaxillary buttress via the transconjunctival and gingivobuccal approaches without any skin incisions. Methods We examined 15 zygomatic fracture patients who underwent two-point fixation during a 3-year period. Stability was evaluated using three-dimensional facial bone computed tomography. Superoinferior and anteroposterior displacement of the zygoma was quantified. The aesthetic appearance of the periorbital region was evaluated using indirect anthropometry with standardized clinical photographs. The ratios between the eye fissure height and width, and lower iris coverage ratio were used to evaluate aesthetical changes. The bony displacement and aesthetic ratios were analyzed using Wilcoxon or Friedman tests. The correlation between the preoperative zygoma position and anthropometric values was analyzed. Results The positions of the zygoma were similar to those on the contralateral side at the long-term follow-up. The preoperative anthropometric measurements on the fractured side differed from those on the contralateral side, although these values were close to the normal values at the long-term follow-up. Furthermore, we noted that the anteroposterior displacement strongly positively correlated with the lower iris coverage rate (Spearman's coefficient=0.678, P=0.005). Conclusions Two-point fixation of zygomatic fractures achieved stable outcomes on long-term follow-up, and also appeared to be reliable in restoring the aesthetic appearance of the periorbital region.

유용미생물처리 음식물쓰레기와 계분 혼합물 퇴비화 특성 (Composting Characteristics of Food Waste - Poultry Manure Mixture Inoculated with Effective Microorganisms)

  • 홍지형;박금주
    • 한국축산시설환경학회지
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    • 제15권1호
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    • pp.59-68
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    • 2009
  • 농업은 작물잔사, 가축분뇨, 음식쓰레기 등의 지역자원을 퇴비화하여 이용하는 순환산업이며, 작물 생육은 빛, 물, 공기, 온도 및 양분 등이 필요하며 유해물질이 없어야한다. 유용미생물처리 음식쓰레기와 계분혼합물 횡형 밀폐원통형 교반방식 퇴비화처리시설에서 얻어진 최종퇴비는 발아율, 산소호흡지수 및 염분농도 등의 수치가 작물 생육에 유해하므로 부적합하였다. 생산된 유용미생물처리 음식쓰레기와 계분혼합물 퇴비를 분석한 결과, 퇴비공정규격, 건물기준 유기물 함량 60% 이상, 유기물대 질소비 50 이하, 탄질비 20 이하를 충족하고, 중금속함량이 미량 함유된 것으로 나타났으나, 발아율이 60% 이하, 칼리 성분이 1.2%,dm 이상 및 염분농도가 1.4%, dm 이상 등으로서 부적합한 것으로 판정되었다. 생물계폐기물 자원순환을 위한 유용미생물처리 고속퇴비화시설의 건설은 환경 친화적인 양질퇴비생산으로서 지역자원을 순환 이용하는 사회 구축이 목표이므로, 인근주민과 주변 환경에 악영향을 차단하기 위하여 양질퇴비 생산과 함께, 오폐수, 분진, 소음, 진동, 악취 및 이물질을 분리 배출하는 고효율설비가 부수적으로 반드시 필요하였다.

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자근(紫根)으로부터 분리한 Naphthoquinone류 색소의 당(糖) 및 산(酸)에 대한 안정성 (Stability of Naphthoquinone Pigments Isolated from the Roots of Lithospermum erythrorhizon by Various Sugars and Acids)

  • 정미숙;이미순
    • 한국식품과학회지
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    • 제26권2호
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    • pp.157-161
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    • 1994
  • 우리나라에 자생하는 야생 식용 식물자원 개발의 일환으로 예로부터 사용되어온 천연 착색료인 자근(Lithospermum erythrorhizon)으로부터 acetylshikonin과 isobutylshikonin을 천연착색료로 사용하기 위하여 당 및 산에 대한 안정성 연구를 하였다. Aceyshikonin 색소의 산성용액(pH 5)에서는 0.6 M의 단당류와 0.3 M의 이당류가 첨가되었을 때 유의적인 흡광도의 증가가 있었다. Acetylshikonin pH 9 용액에서는 0.1 M 과당, 0.005 M 맥아당, 0.6 M 단당류 및 0.3 M 이당류가 첨가되었을 때, isobutylshikonin pH 9 용액의 경우 0.1 및 0.6 M 과당을 첨가 하였을 때 저장기간 동안 당을 첨가하지 않은 실험군에 비하여 흡광도, 즉 색소함량이 유의적으로 높게 나타났다. Acetylshikonin 색소용액에 산을 첨가하여 저장하였을 때 1 meq의 citric, fumaric, oxalic, tartaric 및 phosphoric acid 첨가군에서 색소잔존량의 유의적 증가를 보였으며 10 meq ascorbic acid가 첨가되었을 때 육안으로 관찰되어지는 색소의 변색을 일으켰다. 따라서 자근에서 분리된 acetylshikonin과 isobutylshikonin은 당 및 산이 첨가되는 식품에서 비교적 안정하게 사용될 수 있다고 사료된다.

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축육과 유사한 텍스쳐를 가진 어육단백질 농축물의 가공조건 및 저장중의 품질변화 -제 2 보 : 저장중의 품질변화- (Processing Conditions and Quality Stability during Storage of Meaty Textured Fish Protein Concentrate -II. Quality Stability during Storage and Utilization of Meaty Textured Fish Protein Concentrate from Filefish and Sandfish-)

  • 이응호;조덕제;전중균;차용준;김세권
    • 한국식품과학회지
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    • 제14권1호
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    • pp.43-48
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    • 1982
  • 말쥐치 및 도루묵을 보다 효과적으로 이용하기 위하여, 축육과 유사한 텍스쳐를 가진 어육단백질농축물 저장 중의 품질 안정성 및 이용방안에 대하여 검토하였다. 제품은 함기포장하여 상온에 저장하여도 복수성, TBA값 및 갈변도 등에 큰 변화없이 90일간 품질이 안정하게 유지되었다. 햄버어그 및 튀김어단을 만들때 쇠고기 대신에 축육과 유사한 텍스쳐를 가진 어육단백질농축물을 50%까지 섞어도 맛, 냄새 및 텍스쳐 등에 별다른 손색이 없었다.

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